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The map label for this gene is PE_PGRS42ab [H]

Identifier: 121638368

GI number: 121638368

Start: 2759609

End: 2761192

Strand: Reverse

Name: PE_PGRS42ab [H]

Synonym: BCG_2506c

Alternate gene names: 121638368

Gene position: 2761192-2759609 (Counterclockwise)

Preceding gene: 121638369

Following gene: 121638366

Centisome position: 63.12

GC content: 73.8

Gene sequence:

>1584_bases
GTGTCGTTGGTGATCGCGACGCCGCAGCTGCTGGCAACTGCGGCTTTGGATTTAGCGAGTATTGGTTCGCAGGTGAGCGC
GGCTAATGCGGCCGCGGCGATGCCGACGACGGAAGTGGTGGCTGCGGCTGCCGATGAAGTGTCGGCGGCGATTGCGGGGT
TGTTCGGGGCCCATGCTCGGCAGTATCAGGCGCTCAGCGTACAGGTGGCAGCGTTTCACGAGCAGTTTGTGCAGGCGTTG
ACTGCGGCCGCGGGTCGGTATGCCAGCACTGAGGCCGCTGTTGAGCGGAGTCTGCTGGGTGCGGTGAATGCGCCCACCGA
GGCGCTTTTGGGGCGCCCGTTGATCGGAAACGGCGCCGACGGGACGGCACCCGGGCAGCCTGGCGCGGCCGGCGGGTTGC
TGTTTGGCAACGGTGGCAACGGCGCGGCTGGCGGGTTCGGTCAAACCGGCGGCAGCGGAGGCGCGGCCGGGTTGATCGGC
AACGGCGGCAACGGCGGGGCCGGTGGTACCGGCGCGGCCGGCGGTGCCGGTGGGAACGGGGGGTGGTTGTGGGGCAACGG
CGGCAACGGCGGTGTCGGCGGCACCAGCGTGGCCGCAGGCATCGGGGGTGCGGGCGGTAACGGCGGCAACGCCGGGCTGT
TCGGCCATGGCGGCGCCGGTGGTACCGGCGGCGCCGGCCTCGCCGGGGCAAACGGGGTCAATCCCACGCCCGGCCCCGCG
GCCAGCACCGGGGACAGCCCGGCAGATGTGTCCGGCATCGGTGATCAAACCGGCGGCGACGGCGGCACGGGCGGCCATGG
CACTGCCGGCACGCCGACCGGTGGCACCGGCGGCGACGGTGCCACCGCGACGGCAGGCTCGGGCAAGGCCACCGGCGGTG
CCGGTGGTGACGGCGGTACCGCCGCTGCCGGTGGCGGCGGCGGCAACGGCGGCGACGGCGGAGTCGCGCAGGGCGACATT
GCGAGCGCCTTTGGCGGTGATGGTGGCAACGGGTCCGACGGTGTAGCCGCCGGCAGTGGGGGTGGTAGCGGCGGCGCCGG
AGGCGGCGCTTTCGTACACATCGCCACTGCCACCTCTACCGGTGGTAGCGGCGGTTTCGGTGGTAACGGGGCTGCCAGTG
CCGCCTCCGGCGCCGACGGTGGCGCAGGGGGAGCTGGCGGCAATGGTGGCGCCGGCGGGTTGCTATTCGGTGATGGCGGC
AACGGTGGCGCCGGTGGCGCGGGTGGTATCGGTGGTGACGGCGCCACGGGGGGCCCGGGGGAAGCGGCGGCAACGCTGGC
ATCGCGAGGTTTGACAGCCCAGACCCCGAGGCAGAACCCGATGTGGTCGGCGGCAAGGGTGGTGATGGCGGCAAGGGCGG
CAGCGGCCTTGGCGTCGGCGGCGCCGGCGGGACCGGCGGCGCGGGCGGCAACGGCGGCGCCGGCGGGTTGTTGTTCGGCA
ACGGCGGCAACGGCGGCAACGCCGGGGCCGGCGGGGATGGCGGCGCCGGCGTTGCCGGTGGGGTTGGCGGTAACGGCGGC
GGTGGTGGCACCGCGACGTTTCACGAAGACCCGGTCGCTGGTGTCTGGGCGGTCGGTGGCGTAG

Upstream 100 bases:

>100_bases
AGGGCCGTCGCGGCCATAGTCAGGGCCGCCAGCCAGCGACCAAAGGTCACGTGGCCGCTGGGGACACGGTGCGGCGATAT
GGGGTATCGGGAGGTGCGAG

Downstream 100 bases:

>100_bases
GTGGTGATGGTGGCTCCGGCGGCAGCTCGCTTGGTGTCGGCGGGGTGGGCGGAGCCGGTGGCGTGGGTGGCAAGGGTGGC
GCCAGCGGCATGTTGATCGG

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MSLVIATPQLLATAALDLASIGSQVSAANAAAAMPTTEVVAAAADEVSAAIAGLFGAHARQYQALSVQVAAFHEQFVQAL
TAAAGRYASTEAAVERSLLGAVNAPTEALLGRPLIGNGADGTAPGQPGAAGGLLFGNGGNGAAGGFGQTGGSGGAAGLIG
NGGNGGAGGTGAAGGAGGNGGWLWGNGGNGGVGGTSVAAGIGGAGGNGGNAGLFGHGGAGGTGGAGLAGANGVNPTPGPA
ASTGDSPADVSGIGDQTGGDGGTGGHGTAGTPTGGTGGDGATATAGSGKATGGAGGDGGTAAAGGGGGNGGDGGVAQGDI
ASAFGGDGGNGSDGVAAGSGGGSGGAGGGAFVHIATATSTGGSGGFGGNGAASAASGADGGAGGAGGNGGAGGLLFGDGG
NGGAGGAGGIGGDGATGGPGEAAATLASRGLTAQTPRQNPMWSAARVVMAARAAAALASAAPAGPAARAATAAPAGCCSA
TAATAATPGPAGMAAPALPVGLAVTAAVVAPRRFTKTRSLVSGRSVA

Sequences:

>Translated_527_residues
MSLVIATPQLLATAALDLASIGSQVSAANAAAAMPTTEVVAAAADEVSAAIAGLFGAHARQYQALSVQVAAFHEQFVQAL
TAAAGRYASTEAAVERSLLGAVNAPTEALLGRPLIGNGADGTAPGQPGAAGGLLFGNGGNGAAGGFGQTGGSGGAAGLIG
NGGNGGAGGTGAAGGAGGNGGWLWGNGGNGGVGGTSVAAGIGGAGGNGGNAGLFGHGGAGGTGGAGLAGANGVNPTPGPA
ASTGDSPADVSGIGDQTGGDGGTGGHGTAGTPTGGTGGDGATATAGSGKATGGAGGDGGTAAAGGGGGNGGDGGVAQGDI
ASAFGGDGGNGSDGVAAGSGGGSGGAGGGAFVHIATATSTGGSGGFGGNGAASAASGADGGAGGAGGNGGAGGLLFGDGG
NGGAGGAGGIGGDGATGGPGEAAATLASRGLTAQTPRQNPMWSAARVVMAARAAAALASAAPAGPAARAATAAPAGCCSA
TAATAATPGPAGMAAPALPVGLAVTAAVVAPRRFTKTRSLVSGRSVA
>Mature_526_residues
SLVIATPQLLATAALDLASIGSQVSAANAAAAMPTTEVVAAAADEVSAAIAGLFGAHARQYQALSVQVAAFHEQFVQALT
AAAGRYASTEAAVERSLLGAVNAPTEALLGRPLIGNGADGTAPGQPGAAGGLLFGNGGNGAAGGFGQTGGSGGAAGLIGN
GGNGGAGGTGAAGGAGGNGGWLWGNGGNGGVGGTSVAAGIGGAGGNGGNAGLFGHGGAGGTGGAGLAGANGVNPTPGPAA
STGDSPADVSGIGDQTGGDGGTGGHGTAGTPTGGTGGDGATATAGSGKATGGAGGDGGTAAAGGGGGNGGDGGVAQGDIA
SAFGGDGGNGSDGVAAGSGGGSGGAGGGAFVHIATATSTGGSGGFGGNGAASAASGADGGAGGAGGNGGAGGLLFGDGGN
GGAGGAGGIGGDGATGGPGEAAATLASRGLTAQTPRQNPMWSAARVVMAARAAAALASAAPAGPAARAATAAPAGCCSAT
AATAATPGPAGMAAPALPVGLAVTAAVVAPRRFTKTRSLVSGRSVA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 45748; Mature: 45616

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVIATPQLLATAALDLASIGSQVSAANAAAAMPTTEVVAAAADEVSAAIAGLFGAHAR
CEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
QYQALSVQVAAFHEQFVQALTAAAGRYASTEAAVERSLLGAVNAPTEALLGRPLIGNGAD
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCC
GTAPGQPGAAGGLLFGNGGNGAAGGFGQTGGSGGAAGLIGNGGNGGAGGTGAAGGAGGNG
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
GWLWGNGGNGGVGGTSVAAGIGGAGGNGGNAGLFGHGGAGGTGGAGLAGANGVNPTPGPA
CEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
ASTGDSPADVSGIGDQTGGDGGTGGHGTAGTPTGGTGGDGATATAGSGKATGGAGGDGGT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
AAAGGGGGNGGDGGVAQGDIASAFGGDGGNGSDGVAAGSGGGSGGAGGGAFVHIATATST
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCC
GGSGGFGGNGAASAASGADGGAGGAGGNGGAGGLLFGDGGNGGAGGAGGIGGDGATGGPG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC
EAAATLASRGLTAQTPRQNPMWSAARVVMAARAAAALASAAPAGPAARAATAAPAGCCSA
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHH
TAATAATPGPAGMAAPALPVGLAVTAAVVAPRRFTKTRSLVSGRSVA
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SLVIATPQLLATAALDLASIGSQVSAANAAAAMPTTEVVAAAADEVSAAIAGLFGAHAR
EEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
QYQALSVQVAAFHEQFVQALTAAAGRYASTEAAVERSLLGAVNAPTEALLGRPLIGNGAD
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCC
GTAPGQPGAAGGLLFGNGGNGAAGGFGQTGGSGGAAGLIGNGGNGGAGGTGAAGGAGGNG
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
GWLWGNGGNGGVGGTSVAAGIGGAGGNGGNAGLFGHGGAGGTGGAGLAGANGVNPTPGPA
CEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
ASTGDSPADVSGIGDQTGGDGGTGGHGTAGTPTGGTGGDGATATAGSGKATGGAGGDGGT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
AAAGGGGGNGGDGGVAQGDIASAFGGDGGNGSDGVAAGSGGGSGGAGGGAFVHIATATST
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCC
GGSGGFGGNGAASAASGADGGAGGAGGNGGAGGLLFGDGGNGGAGGAGGIGGDGATGGPG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC
EAAATLASRGLTAQTPRQNPMWSAARVVMAARAAAALASAAPAGPAARAATAAPAGCCSA
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHH
TAATAATPGPAGMAAPALPVGLAVTAAVVAPRRFTKTRSLVSGRSVA
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]