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The map label for this gene is 121638339

Identifier: 121638339

GI number: 121638339

Start: 2722106

End: 2723362

Strand: Reverse

Name: 121638339

Synonym: BCG_2476c

Alternate gene names: NA

Gene position: 2723362-2722106 (Counterclockwise)

Preceding gene: 121638340

Following gene: 121638338

Centisome position: 62.26

GC content: 65.47

Gene sequence:

>1257_bases
ATGTCGGGCACCGTTGTGGCAGTGCCGCCACGGGTGGCGCGTGCGCTGGACCTGCTGAATTTCTCGTTGGCTGATGTTCG
CGACGGTCTGGGCCCCTATCTGTCGATATACCTCCTGTTGATCCACGATTGGGATCAAGCCTCGATCGGGTTCGTCATGG
CGGTCGGCGGCATTGCGGCCATCGTGGCCCAGACGCCGATTGGCGCCCTGGTGGACCGGACCACGGCCAAGCGGGCGCTG
GTCGTCGCCGGCGCGGTGCTGGTCACCGCCGCCGCAGTGGCGATGCCGCTGTTTGCGGGCTTGTATTCCATCTCGGTGCT
GCAGGCCGTCACCGGGATCGCCAGCTCGGTTTTCGCTCCGGCGTTGGCGGCGATCACGTTGGGTGCTGTCGGTCCTCAGT
TTTTCGCCAGACGGATTGGGCGTAACGAAGCGTTCAACCACGCCGGTAACGCGTCGGCGGCTGGGGCGACCGGCGCGCTG
GCGTACTTCTTCGGGCCGGTGGTGGTGTTCTGGGTGCTGGCCGGCATGGCGTTGATCAGCGTGCTGGCGACACTGCGGAT
CCCGCCGGACGCGGTCGACCACGATTTAGCGCGTGGTATGGACCATGCGCCCGGCGAGCCGCATCCGCAGCCGTCGCGGT
TCACCGTGTTGGCGCACAACCGCGAACTGGTGATCTTCGGGGCGGCGGTTGTCGCGTTCCACTTCGCCAACGCGGCGATG
CTGCCGCTGGTCGGCGAGCTGTTGGCGTTGCACAATCGAGACGAAGGAACGGCGCTGATGTCGTCGTGCATCGTCGCGGC
GCAGGTCGTGATGGTGCCGGTGGCGTATGTGGTCGGGACCAGGGCCGACGCGTGGGGGCGAAAGCCGATCTTTTTGGTGG
GGTTCGCTGTCTTGACCGCTCGCGGGTTCCTCTACACGTTGTCGGATAACTCCTACTGGCTGGTGGGCGTGCAGTTGCTC
GACGGTATCGGAGCCGGCATTTTCGGGGCGTTGTTTCCCCTTGTCGTACAGGACGTCACACACGGAACGGGACATTTCAA
TATCAGCCTCGGGGCGGTAACCACGGCAACGGGCATTGGTGCCGCGCTGTCTAATCTTGTTGCCGGCTGGATCGTGGTCG
TCGCGGGCTATGACGCGGCATTCATGTCGCTGGGTGCGCTCGCCGGGGCCGGCTTCCTCCTGTACCTGGTCGCGATGCCG
GAAACCGTGGATTCGGATGTCCGGGTGCGGTCGCGGCCAACCCTCGGGGGGAAGTGA

Upstream 100 bases:

>100_bases
CAAGGAGACCGTGCAGGACAACGTGTTGCCGACAATCGTGCCACGCAAGCCGTCCCGTTCGGAGCGCCGCGACAAGAGCG
CGTAGCCCCGCGACGACTGC

Downstream 100 bases:

>100_bases
CCAATACCACAGTTCTGTGTCGTCGCTACCGCCAGCCCTCGCTGACTTCGCCTTTTGGTCGGTTACCGGCCGCATATATG
GCATCGGAGACCGCCTTACA

Product: putative integral membrane transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSGTVVAVPPRVARALDLLNFSLADVRDGLGPYLSIYLLLIHDWDQASIGFVMAVGGIAAIVAQTPIGALVDRTTAKRAL
VVAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAPALAAITLGAVGPQFFARRIGRNEAFNHAGNASAAGATGAL
AYFFGPVVVFWVLAGMALISVLATLRIPPDAVDHDLARGMDHAPGEPHPQPSRFTVLAHNRELVIFGAAVVAFHFANAAM
LPLVGELLALHNRDEGTALMSSCIVAAQVVMVPVAYVVGTRADAWGRKPIFLVGFAVLTARGFLYTLSDNSYWLVGVQLL
DGIGAGIFGALFPLVVQDVTHGTGHFNISLGAVTTATGIGAALSNLVAGWIVVVAGYDAAFMSLGALAGAGFLLYLVAMP
ETVDSDVRVRSRPTLGGK

Sequences:

>Translated_418_residues
MSGTVVAVPPRVARALDLLNFSLADVRDGLGPYLSIYLLLIHDWDQASIGFVMAVGGIAAIVAQTPIGALVDRTTAKRAL
VVAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAPALAAITLGAVGPQFFARRIGRNEAFNHAGNASAAGATGAL
AYFFGPVVVFWVLAGMALISVLATLRIPPDAVDHDLARGMDHAPGEPHPQPSRFTVLAHNRELVIFGAAVVAFHFANAAM
LPLVGELLALHNRDEGTALMSSCIVAAQVVMVPVAYVVGTRADAWGRKPIFLVGFAVLTARGFLYTLSDNSYWLVGVQLL
DGIGAGIFGALFPLVVQDVTHGTGHFNISLGAVTTATGIGAALSNLVAGWIVVVAGYDAAFMSLGALAGAGFLLYLVAMP
ETVDSDVRVRSRPTLGGK
>Mature_417_residues
SGTVVAVPPRVARALDLLNFSLADVRDGLGPYLSIYLLLIHDWDQASIGFVMAVGGIAAIVAQTPIGALVDRTTAKRALV
VAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAPALAAITLGAVGPQFFARRIGRNEAFNHAGNASAAGATGALA
YFFGPVVVFWVLAGMALISVLATLRIPPDAVDHDLARGMDHAPGEPHPQPSRFTVLAHNRELVIFGAAVVAFHFANAAML
PLVGELLALHNRDEGTALMSSCIVAAQVVMVPVAYVVGTRADAWGRKPIFLVGFAVLTARGFLYTLSDNSYWLVGVQLLD
GIGAGIFGALFPLVVQDVTHGTGHFNISLGAVTTATGIGAALSNLVAGWIVVVAGYDAAFMSLGALAGAGFLLYLVAMPE
TVDSDVRVRSRPTLGGK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2456_MYCTU (O53183)

Other databases:

- EMBL:   AE000516
- EMBL:   BX842579
- PIR:   G70864
- RefSeq:   NP_216972.1
- RefSeq:   NP_337017.1
- ProteinModelPortal:   O53183
- EnsemblBacteria:   EBMYCT00000003637
- EnsemblBacteria:   EBMYCT00000069096
- GeneID:   887340
- GeneID:   925793
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2531
- KEGG:   mtu:Rv2456c
- TIGR:   MT2531
- TubercuList:   Rv2456c
- GeneTree:   EBGT00050000014800
- HOGENOM:   HBG334587
- OMA:   NHAGNAV
- ProtClustDB:   CLSK872067
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 43134; Mature: 43003

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16cf3ccc)-; HASH(0x1791ed5c)-; HASH(0x1799d71c)-; HASH(0x17959238)-; HASH(0x17770ca8)-; HASH(0x177c7628)-; HASH(0x178f14e4)-; HASH(0x1760c87c)-; HASH(0x16e131ac)-; HASH(0x16745c5c)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTVVAVPPRVARALDLLNFSLADVRDGLGPYLSIYLLLIHDWDQASIGFVMAVGGIAA
CCCCEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHH
IVAQTPIGALVDRTTAKRALVVAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAAITLGAVGPQFFARRIGRNEAFNHAGNASAAGATGALAYFFGPVVVFWVLAGMALIS
HHHHHHHHCCCHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLATLRIPPDAVDHDLARGMDHAPGEPHPQPSRFTVLAHNRELVIFGAAVVAFHFANAAM
HHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCEEEEEHHHHHHHHHHCHHH
LPLVGELLALHNRDEGTALMSSCIVAAQVVMVPVAYVVGTRADAWGRKPIFLVGFAVLTA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RGFLYTLSDNSYWLVGVQLLDGIGAGIFGALFPLVVQDVTHGTGHFNISLGAVTTATGIG
CCEEEEECCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHH
AALSNLVAGWIVVVAGYDAAFMSLGALAGAGFLLYLVAMPETVDSDVRVRSRPTLGGK
HHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCH
>Mature Secondary Structure 
SGTVVAVPPRVARALDLLNFSLADVRDGLGPYLSIYLLLIHDWDQASIGFVMAVGGIAA
CCCEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHH
IVAQTPIGALVDRTTAKRALVVAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAAITLGAVGPQFFARRIGRNEAFNHAGNASAAGATGALAYFFGPVVVFWVLAGMALIS
HHHHHHHHCCCHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLATLRIPPDAVDHDLARGMDHAPGEPHPQPSRFTVLAHNRELVIFGAAVVAFHFANAAM
HHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCEEEEEHHHHHHHHHHCHHH
LPLVGELLALHNRDEGTALMSSCIVAAQVVMVPVAYVVGTRADAWGRKPIFLVGFAVLTA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RGFLYTLSDNSYWLVGVQLLDGIGAGIFGALFPLVVQDVTHGTGHFNISLGAVTTATGIG
CCEEEEECCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHH
AALSNLVAGWIVVVAGYDAAFMSLGALAGAGFLLYLVAMPETVDSDVRVRSRPTLGGK
HHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036