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The map label for this gene is rbsK [H]

Identifier: 121638318

GI number: 121638318

Start: 2698400

End: 2699314

Strand: Direct

Name: rbsK [H]

Synonym: BCG_2455

Alternate gene names: 121638318

Gene position: 2698400-2699314 (Clockwise)

Preceding gene: 121638311

Following gene: 121638319

Centisome position: 61.68

GC content: 68.74

Gene sequence:

>915_bases
ATGGCAAACGCCAGTGAGACTAACGTCGGCCCCATGGCGCCCCGGGTGTGCGTGGTAGGCAGCGTGAACATGGACCTGAC
GTTCGTGGTGGACGCGCTTCCGCGCCCCGGCGAGACGGTGCTTGCGGCGTCGTTGACCCGAACGCCAGGCGGGAAGGGCG
CCAACCAGGCGGTGGCCGCAGCGCGCGCAGGCGCGCAGGTACAGTTCTCCGGTGCATTCGGCGACGATCCAGCCGCCGCC
CAGCTGCGGGCCCACCTGCGCGCCAACGCCGTTGGACTGGACAGGACCGTCACGGTGCCCGGACCGAGCGGGACGGCGAT
TATCGTGGTCGATGCCAGCGCCGAGAACACCGTGCTGGTGGCGCCGGGTGCCAATGCACATCTGACTCCGGTACCCTCGG
CCGTCGCCAACTGCGATGTACTGTTGACCCAGTTGGAGATTCCTGTTGCAACCGCGCTGGCAGCCGCGCGGGCAGCCCAG
TCGGCCGATGCGGTTGTCATGGTCAACGCCTCCCCAGCCGGCCAGGATCGAAGCTCCTTGCAGGACTTGGCCGCTATCGC
CGACGTGGTGATCGCCAACGAGCATGAGGCAAACGACTGGCCGTCGCCACCAACACATTTCGTGATCACCCTGGGTGTGC
GCGGTGCCCGGTACGTCGGCGCGGACGGGGTGTTCGAGGTACCCGCCCCAACGGTAACGCCAGTGGATACCGCCGGCGCC
GGCGACGTATTTGCCGGGGTCCTTGCTGCGAATTGGCCGCGCAACCCAGGTTCGCCGGCCGAGCGACTGCGCGCATTGCG
GCGGGCCTGCGCTGCGGGTGTGCTGGCAACTTTGGTGTCCGGTGCCGGCGACTGCGCACCGGCCGCCGCCGCGATCGATG
CGGCCCTGCGAGCCAACCGCCACAACGGTTCATGA

Upstream 100 bases:

>100_bases
ATCCGCAAGCATGTTCGAATACTGGGACGCGCCACCGACAGGACACCCACTGATACCCTTGGGACAAAAGTGACACAAGT
GATTTCAGCCAACAGCAAGC

Downstream 100 bases:

>100_bases
CCACTGCTACGCACCGAAGGAGACCCGCTGATGCGAACGACCACCGCGGCCGACTTAGCGCTGGCACTCTTCGCGGTTTT
CAGTGTGGTCGGATTCGGCT

Product: ribokinase rbsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MANASETNVGPMAPRVCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAAARAGAQVQFSGAFGDDPAAA
QLRAHLRANAVGLDRTVTVPGPSGTAIIVVDASAENTVLVAPGANAHLTPVPSAVANCDVLLTQLEIPVATALAAARAAQ
SADAVVMVNASPAGQDRSSLQDLAAIADVVIANEHEANDWPSPPTHFVITLGVRGARYVGADGVFEVPAPTVTPVDTAGA
GDVFAGVLAANWPRNPGSPAERLRALRRACAAGVLATLVSGAGDCAPAAAAIDAALRANRHNGS

Sequences:

>Translated_304_residues
MANASETNVGPMAPRVCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAAARAGAQVQFSGAFGDDPAAA
QLRAHLRANAVGLDRTVTVPGPSGTAIIVVDASAENTVLVAPGANAHLTPVPSAVANCDVLLTQLEIPVATALAAARAAQ
SADAVVMVNASPAGQDRSSLQDLAAIADVVIANEHEANDWPSPPTHFVITLGVRGARYVGADGVFEVPAPTVTPVDTAGA
GDVFAGVLAANWPRNPGSPAERLRALRRACAAGVLATLVSGAGDCAPAAAAIDAALRANRHNGS
>Mature_303_residues
ANASETNVGPMAPRVCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAAARAGAQVQFSGAFGDDPAAAQ
LRAHLRANAVGLDRTVTVPGPSGTAIIVVDASAENTVLVAPGANAHLTPVPSAVANCDVLLTQLEIPVATALAAARAAQS
ADAVVMVNASPAGQDRSSLQDLAAIADVVIANEHEANDWPSPPTHFVITLGVRGARYVGADGVFEVPAPTVTPVDTAGAG
DVFAGVLAANWPRNPGSPAERLRALRRACAAGVLATLVSGAGDCAPAAAAIDAALRANRHNGS

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=271, Percent_Identity=29.520295202952, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1790193, Length=259, Percent_Identity=35.1351351351351, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI87082343, Length=253, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=268, Percent_Identity=31.7164179104478, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI20128807, Length=280, Percent_Identity=35, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24583886, Length=287, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30280; Mature: 30149

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANASETNVGPMAPRVCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAA
CCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCHHHHHH
ARAGAQVQFSGAFGDDPAAAQLRAHLRANAVGLDRTVTVPGPSGTAIIVVDASAENTVLV
HHCCCEEEECCCCCCCHHHHHHHHHHHHCEECCCCEEECCCCCCCEEEEEECCCCCEEEE
APGANAHLTPVPSAVANCDVLLTQLEIPVATALAAARAAQSADAVVMVNASPAGQDRSSL
ECCCCCCCCCCCHHHHHHHEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHH
QDLAAIADVVIANEHEANDWPSPPTHFVITLGVRGARYVGADGVFEVPAPTVTPVDTAGA
HHHHHHHHHHEECCCCCCCCCCCCCEEEEEEECCCCEEECCCCEEECCCCCCCCCCCCCC
GDVFAGVLAANWPRNPGSPAERLRALRRACAAGVLATLVSGAGDCAPAAAAIDAALRANR
CHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
HNGS
CCCC
>Mature Secondary Structure 
ANASETNVGPMAPRVCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAA
CCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCHHHHHH
ARAGAQVQFSGAFGDDPAAAQLRAHLRANAVGLDRTVTVPGPSGTAIIVVDASAENTVLV
HHCCCEEEECCCCCCCHHHHHHHHHHHHCEECCCCEEECCCCCCCEEEEEECCCCCEEEE
APGANAHLTPVPSAVANCDVLLTQLEIPVATALAAARAAQSADAVVMVNASPAGQDRSSL
ECCCCCCCCCCCHHHHHHHEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHH
QDLAAIADVVIANEHEANDWPSPPTHFVITLGVRGARYVGADGVFEVPAPTVTPVDTAGA
HHHHHHHHHHEECCCCCCCCCCCCCEEEEEEECCCCEEECCCCEEECCCCCCCCCCCCCC
GDVFAGVLAANWPRNPGSPAERLRALRRACAAGVLATLVSGAGDCAPAAAAIDAALRANR
CHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
HNGS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]