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The map label for this gene is nadD

Identifier: 121638302

GI number: 121638302

Start: 2683365

End: 2684000

Strand: Reverse

Name: nadD

Synonym: BCG_2437c

Alternate gene names: 121638302

Gene position: 2684000-2683365 (Counterclockwise)

Preceding gene: 121638305

Following gene: 121638301

Centisome position: 61.36

GC content: 64.62

Gene sequence:

>636_bases
ATGGGTGGGACGTTCGACCCCATCCACTACGGCCACCTGGTTGCCGCCAGCGAGGTGGCCGACCTGTTCGATCTCGACGA
AGTGGTATTCGTGCCCAGCGGGCAACCCTGGCAAAAGGGTCGACAGGTCTCCGCCGCCGAGCACCGCTACCTAATGACGG
TGATCGCCACCGCCTCCAATCCCCGATTCTCTGTGAGCCGGGTCGACATCGACCGCGGCGGACCCACCTACACCAAGGAC
ACGCTGGCCGATCTGCATGCTTTGCACCCGGACTCTGAGCTGTACTTCACCACCGGCGCCGATGCGCTAGCTTCCATAAT
GTCCTGGCAGGGCTGGGAGGAGCTGTTCGAATTGGCGCGGTTCGTGGGGGTCAGCCGGCCCGGCTACGAGTTGCGCAACG
AACACATCACTAGCCTGCTGGGTCAGCTGGCCAAGGATGCGTTGACTCTGGTCGAGATCCCGGCGCTGGCCATTTCGTCG
ACCGACTGCCGTCAGCGCGCCGAGCAGTCCCGGCCGCTGTGGTACCTGATGCCCGACAGCGTCGTGCAGTATGTCTCCAA
GTGCCGGCTCTACTGTGGCGCCTGCGACGCGGGCGCGCGTTCAACGACCAGCCTGGCCGCTGGGAATGGCCTATGA

Upstream 100 bases:

>100_bases
ATGGCTGCTCGCTTAGGCTGGCTGGCAGTTGCCGCGAACGGAACTGCGGCAAGATACTCCAGTAAGCTGGCCAATCGTGC
ATGGGCGTCGATTGGGAGTC

Downstream 100 bases:

>100_bases
CCGCCAACCGGGAAGCCATCGACATGGCGAGGGTGGCCGCCGGCGCGGCCGCCGCCAAGCTCGCCGATGACGTCGTGGTC
ATCGATGTCTCCGGGCAGCT

Product: nicotinic acid mononucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MGGTFDPIHYGHLVAASEVADLFDLDEVVFVPSGQPWQKGRQVSAAEHRYLMTVIATASNPRFSVSRVDIDRGGPTYTKD
TLADLHALHPDSELYFTTGADALASIMSWQGWEELFELARFVGVSRPGYELRNEHITSLLGQLAKDALTLVEIPALAISS
TDCRQRAEQSRPLWYLMPDSVVQYVSKCRLYCGACDAGARSTTSLAAGNGL

Sequences:

>Translated_211_residues
MGGTFDPIHYGHLVAASEVADLFDLDEVVFVPSGQPWQKGRQVSAAEHRYLMTVIATASNPRFSVSRVDIDRGGPTYTKD
TLADLHALHPDSELYFTTGADALASIMSWQGWEELFELARFVGVSRPGYELRNEHITSLLGQLAKDALTLVEIPALAISS
TDCRQRAEQSRPLWYLMPDSVVQYVSKCRLYCGACDAGARSTTSLAAGNGL
>Mature_210_residues
GGTFDPIHYGHLVAASEVADLFDLDEVVFVPSGQPWQKGRQVSAAEHRYLMTVIATASNPRFSVSRVDIDRGGPTYTKDT
LADLHALHPDSELYFTTGADALASIMSWQGWEELFELARFVGVSRPGYELRNEHITSLLGQLAKDALTLVEIPALAISST
DCRQRAEQSRPLWYLMPDSVVQYVSKCRLYCGACDAGARSTTSLAAGNGL

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=207, Percent_Identity=30.4347826086957, Blast_Score=102, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_MYCBO (Q7TYM1)

Other databases:

- EMBL:   BX248342
- RefSeq:   NP_856093.1
- ProteinModelPortal:   Q7TYM1
- SMR:   Q7TYM1
- EnsemblBacteria:   EBMYCT00000017423
- GeneID:   1094273
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2444c
- GeneTree:   EBGT00050000016650
- HOGENOM:   HBG739448
- OMA:   IFMPAGN
- ProtClustDB:   PRK00071
- BioCyc:   MBOV233413:MB2444C-MONOMER
- BRENDA:   2.7.7.18
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.18

Molecular weight: Translated: 23083; Mature: 22952

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGTFDPIHYGHLVAASEVADLFDLDEVVFVPSGQPWQKGRQVSAAEHRYLMTVIATASN
CCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHCCCCCHHHHHEEEEEEEECCC
PRFSVSRVDIDRGGPTYTKDTLADLHALHPDSELYFTTGADALASIMSWQGWEELFELAR
CCEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHCCCCHHHHHHHHH
FVGVSRPGYELRNEHITSLLGQLAKDALTLVEIPALAISSTDCRQRAEQSRPLWYLMPDS
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCHH
VVQYVSKCRLYCGACDAGARSTTSLAAGNGL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GGTFDPIHYGHLVAASEVADLFDLDEVVFVPSGQPWQKGRQVSAAEHRYLMTVIATASN
CCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHCCCCCHHHHHEEEEEEEECCC
PRFSVSRVDIDRGGPTYTKDTLADLHALHPDSELYFTTGADALASIMSWQGWEELFELAR
CCEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHCCCCHHHHHHHHH
FVGVSRPGYELRNEHITSLLGQLAKDALTLVEIPALAISSTDCRQRAEQSRPLWYLMPDS
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCHH
VVQYVSKCRLYCGACDAGARSTTSLAAGNGL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972