Click here to switch to the map view.

The map label for this gene is hrcA [H]

Identifier: 121638253

GI number: 121638253

Start: 2619084

End: 2620115

Strand: Reverse

Name: hrcA [H]

Synonym: BCG_2388c

Alternate gene names: 121638253

Gene position: 2620115-2619084 (Counterclockwise)

Preceding gene: 121638255

Following gene: 121638252

Centisome position: 59.89

GC content: 64.05

Gene sequence:

>1032_bases
ATGGGAAGCGCCGACGAGCGTCGCTTTGAGGTGCTGCGTGCCATCGTCGCCGACTTCGTTGCAACCCAGGAACCGATCGG
CTCCAAATCCCTGGTGGAACGCCATAACCTGGGAGTCTCGTCGGCCACAGTCCGCAATGACATGGCGGTGCTGGAAGCCG
AAGGCTATATCACTCAGCCACACACCAGTTCCGGACGCGTGCCCACGGAGAAGGGCTACCGCGAGTTCGTCGACCAGCTC
GAGGACGTCAAACCCCTATCGTCGGCCGAGCGCCGGGCGATCCAGAGCTTCCTTGAATCCGGTGTCGATCTCGACGACGT
GCTGCGCCGTGCCGTGCGATTGCTGGCGCAGCTGACCCGCCAGGTGGCCGTCGTGCAGTACCCGACGTTGTCAACGTCGA
CCGTTCGCCACTTGGAGGTGATCGCGCTGACACCGGCCCGGCTGCTGATGGTGGTCATCACCGACTCCGGCCGGGTTGAT
CAGCGCATCGTCGAACTCGGCGATGTCATCGACGATCACCAGCTAGCCCAGCTGCGTGAAATACTCGGCCAGGCGCTGGA
AGGCAAGAAGCTTTCAGCGGCTTCGGTGGCGGTCGCCGACCTCGCCAGCCAGCTGGGCGGCGCCGGCGGATTGGGCGACG
CCGTGGGCCGCGCGGCGACCGTATTGCTGGAGTCGCTAGTGGAGCACACCGAGGAACGCCTTTTGCTGGGCGGTACCGCC
AACCTAACCCGCAACGCTGCGGACTTCGGTGGTTCACTGCGGTCAATATTGGAAGCACTTGAGGAGCAGGTGGTGGTGTT
GCGGCTGCTGGCGGCTCAGCAGGAAGCCGGCAAGGTGACGGTTCGCATAGGTCATGAGACGGCGTCTGAGCAGATGGTGG
GCACCTCGATGGTGTCGACGGCCTACGGTACCGCCCATACCGTCTACGGCGGTATGGGTGTGGTGGGCCCCACCCGGATG
GACTATCCGGGAACTATCGCCAGCGTGGCTGCGGTTGCTCTTTATATCGGCGACGTCCTGGGTGCTCGATGA

Upstream 100 bases:

>100_bases
CCCCTGACCATCGGCAGACGCCTGCTAGATGACGGTCAGTGGCCGCCGAGAACGTAAAATGAAGCCGGTCAGGCAGCGTA
AGAAGTGAGGTGAGCAGTCG

Downstream 100 bases:

>100_bases
ACGCGCACCTGCTGCAGGGTTTGTGGATAGCCGCTTGAGAAGCGGCATAAAGACGCGGCATAGGAGAATCAAGCGTGGCA
CGCGATTATTACGGGCTGCT

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MGSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDQL
EDVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTRQVAVVQYPTLSTSTVRHLEVIALTPARLLMVVITDSGRVD
QRIVELGDVIDDHQLAQLREILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTA
NLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVSTAYGTAHTVYGGMGVVGPTRM
DYPGTIASVAAVALYIGDVLGAR

Sequences:

>Translated_343_residues
MGSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDQL
EDVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTRQVAVVQYPTLSTSTVRHLEVIALTPARLLMVVITDSGRVD
QRIVELGDVIDDHQLAQLREILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTA
NLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVSTAYGTAHTVYGGMGVVGPTRM
DYPGTIASVAAVALYIGDVLGAR
>Mature_342_residues
GSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDQLE
DVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTRQVAVVQYPTLSTSTVRHLEVIALTPARLLMVVITDSGRVDQ
RIVELGDVIDDHQLAQLREILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTAN
LTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVSTAYGTAHTVYGGMGVVGPTRMD
YPGTIASVAAVALYIGDVLGAR

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 36447; Mature: 36316

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQP
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHCHHEEECCCCEECC
HTSSGRVPTEKGYREFVDQLEDVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTR
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QVAVVQYPTLSTSTVRHLEVIALTPARLLMVVITDSGRVDQRIVELGDVIDDHQLAQLRE
HHHHHCCCCCCHHHHHHHHHEEECHHHEEEEEEECCCCHHHHHHHHHHHHCHHHHHHHHH
ILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTA
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCC
NLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVST
HHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHH
AYGTAHTVYGGMGVVGPTRMDYPGTIASVAAVALYIGDVLGAR
HHCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQP
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHCHHEEECCCCEECC
HTSSGRVPTEKGYREFVDQLEDVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTR
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QVAVVQYPTLSTSTVRHLEVIALTPARLLMVVITDSGRVDQRIVELGDVIDDHQLAQLRE
HHHHHCCCCCCHHHHHHHHHEEECHHHEEEEEEECCCCHHHHHHHHHHHHCHHHHHHHHH
ILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTA
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCC
NLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVST
HHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHH
AYGTAHTVYGGMGVVGPTRMDYPGTIASVAAVALYIGDVLGAR
HHCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA