Click here to switch to the map view.

The map label for this gene is PPE35a [H]

Identifier: 121637823

GI number: 121637823

Start: 2170895

End: 2172772

Strand: Reverse

Name: PPE35a [H]

Synonym: BCG_1957c

Alternate gene names: 121637823

Gene position: 2172772-2170895 (Counterclockwise)

Preceding gene: 121637824

Following gene: 121637822

Centisome position: 49.67

GC content: 61.4

Gene sequence:

>1878_bases
ATGCATTACTCAGTGTTGCCGCCGGAGATCAACTCGGCCTTGATCTTCGCCGGGGCGGGCTCCGGACCGATGCTGGCGGC
GGCGTCGGCCTGGGACGGGCTGGCAACCGAATTAGCCTCGGCTGCTGTCTCTTTCGGCTCGGTGACAGCCGGGCTGGTCG
GCGGGTCGTGGCAGGGTCGGTCATCGGTGGCGATGGCAGCGGCGGCAGCCCCGTATGCGGGGTGGCTGGCCGCGGCGGCG
ACCCAGGCCGAGCAGGCGGCCACCCAGGCCCAGGTGATGGTGGCCGAGTTCGAGGCTGTGCGGCTGGCGATGGTACAACC
GGCGCTGGTGGCCGCCAACCGTTCCGGCCTCATATCGCTGGTGATATCGAACCTTTTTGGTCAAAACGCTCCCGCGATCG
CGGCCGCCGAAGCCGCATACGAGGAGATGTGGGCTCTGGATGTATCGGCGATGGCGGCCTACCATTCCGGGGCGTCGGCG
GTCGCTGTGGCGCTACCGGCATTCGCCCTCCCGCTGCGGCTTCCGGCGGGTCTGGCGGCCGGGCCCGCGGCCGTGGTGAC
CGCGCTCACCACGGCCGTGGGCATGCCGACTTTTGCCGGCCGGGCGATCGCCGCTAGCCTCGGCTTGGCCAACGTCGGTG
GTGGCAACCTCGGCAATGCCAACAATGGGCTCGGCAACATCGGCAACGCCAACCTTGGCAACAACAATCTGGGGTCCGGC
AACTTCGGTAGCTTCAATATCGGCTCGGCCAACCTAGGTGGCAACAACATCGGCATAGGAAACGCGGGCGCCAACAACTT
CGGACTTGCAAACCTGGGCAATTTGAACACGGGATTCGCCAATGCAGGCATCGGCAACTTCGGAATTGCGAACACCGGCA
ACAACAATATCGGCAACGGCCTGACTGGAAACAACCAAATCGGCATTGGCGGACTCAATTCCGGCAACGGTAACGTCGGA
TTATTCAACGCGGGTAGCGCCAATATCGGTTTCTTCAACTCCGGCAATGGCAACTTTGGCATCGGGAACTCCGGTAACTT
CAGCACTGGCCTGTTCAACCCCGGACACGGCAACACCGGATTCCTGAATGCGGGCTCTTTCAATACGGGCATGTTCGACG
TTGGGAACGCGAACACCGGCAGCTTCAACGTCGGCCACTACAACTTCGGTGCCTTCAACCCGGGCCCGTCGAACACGGGT
ACCTTCAACACGGGCGGCGCCAACACCGGCTGGTTCAACACAGGAAGCATCAACACCGGCGCCTTCAACATAGGCGACAT
GAATAACGGCTTGTTCAACACGGGCGACATGAACAATGGTGTCTTTTACCGTGGTGTGGGCCAAGGCAGCCTGCAGTTCG
CCATCACCAGCCCTGATTTGACGCTTCCGTCTCTGGAAATACCCGGAATCTCGGTTCCCGCGTTCAGCCTGCCCGCGATA
ACCTTGCCGTCGTTGACGATTCCGGCGGTGACGACGCCGGCCAACGTTACCGTGGGTGCGTTTGATTTGCCGGGGTTGAC
GGTGCCGTCGTTGACGATTCCAGCGGCGATGACGCCAGCTAACATCACGGTGGGTGCGTTTGATTTGCCGGGGTTGACGG
TGCCGTCGTTGACGATTCCAGCTACAACGACACCAGCCAACATCACGGTAGGTGCGTTTAACTTGCCTCAGTTGAGTATT
CCGTCGGTGACGTTTCCGCCGATCACGATTCCGGCTGGCACAGCGCTAGGTGCGTTCAATCTGCCGACGCTGAGTATTCC
GTCGGTGACGGTTCCGCCGATCACGATTCCGGCTGGCAACCACTGTCGGCGGATTTACGCTACCCACGATACACACCCCG
TTAATAAGTACACCCCAAATAAGTATAGGCGGCTTTAG

Upstream 100 bases:

>100_bases
TTCAAGATCTCCGCGTACTCTCATGCGCTACGAACGAGTCAGCGACGACGGGCGTGTGACCTTTCATCAGCACCAGGCTC
ACCCCGGAAGGTGGGGAGCG

Downstream 100 bases:

>100_bases
CACTCCCGGCATAGCCACGCAAGCAAATTCTGGTGTCATCAATCTTCCCACCTTTAGCCTTAACGGCATTACGATAACTA
ATTTGGTGGTGTTCATTCCG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MHYSVLPPEINSALIFAGAGSGPMLAAASAWDGLATELASAAVSFGSVTAGLVGGSWQGRSSVAMAAAAAPYAGWLAAAA
TQAEQAATQAQVMVAEFEAVRLAMVQPALVAANRSGLISLVISNLFGQNAPAIAAAEAAYEEMWALDVSAMAAYHSGASA
VAVALPAFALPLRLPAGLAAGPAAVVTALTTAVGMPTFAGRAIAASLGLANVGGGNLGNANNGLGNIGNANLGNNNLGSG
NFGSFNIGSANLGGNNIGIGNAGANNFGLANLGNLNTGFANAGIGNFGIANTGNNNIGNGLTGNNQIGIGGLNSGNGNVG
LFNAGSANIGFFNSGNGNFGIGNSGNFSTGLFNPGHGNTGFLNAGSFNTGMFDVGNANTGSFNVGHYNFGAFNPGPSNTG
TFNTGGANTGWFNTGSINTGAFNIGDMNNGLFNTGDMNNGVFYRGVGQGSLQFAITSPDLTLPSLEIPGISVPAFSLPAI
TLPSLTIPAVTTPANVTVGAFDLPGLTVPSLTIPAAMTPANITVGAFDLPGLTVPSLTIPATTTPANITVGAFNLPQLSI
PSVTFPPITIPAGTALGAFNLPTLSIPSVTVPPITIPAGNHCRRIYATHDTHPVNKYTPNKYRRL

Sequences:

>Translated_625_residues
MHYSVLPPEINSALIFAGAGSGPMLAAASAWDGLATELASAAVSFGSVTAGLVGGSWQGRSSVAMAAAAAPYAGWLAAAA
TQAEQAATQAQVMVAEFEAVRLAMVQPALVAANRSGLISLVISNLFGQNAPAIAAAEAAYEEMWALDVSAMAAYHSGASA
VAVALPAFALPLRLPAGLAAGPAAVVTALTTAVGMPTFAGRAIAASLGLANVGGGNLGNANNGLGNIGNANLGNNNLGSG
NFGSFNIGSANLGGNNIGIGNAGANNFGLANLGNLNTGFANAGIGNFGIANTGNNNIGNGLTGNNQIGIGGLNSGNGNVG
LFNAGSANIGFFNSGNGNFGIGNSGNFSTGLFNPGHGNTGFLNAGSFNTGMFDVGNANTGSFNVGHYNFGAFNPGPSNTG
TFNTGGANTGWFNTGSINTGAFNIGDMNNGLFNTGDMNNGVFYRGVGQGSLQFAITSPDLTLPSLEIPGISVPAFSLPAI
TLPSLTIPAVTTPANVTVGAFDLPGLTVPSLTIPAAMTPANITVGAFDLPGLTVPSLTIPATTTPANITVGAFNLPQLSI
PSVTFPPITIPAGTALGAFNLPTLSIPSVTVPPITIPAGNHCRRIYATHDTHPVNKYTPNKYRRL
>Mature_625_residues
MHYSVLPPEINSALIFAGAGSGPMLAAASAWDGLATELASAAVSFGSVTAGLVGGSWQGRSSVAMAAAAAPYAGWLAAAA
TQAEQAATQAQVMVAEFEAVRLAMVQPALVAANRSGLISLVISNLFGQNAPAIAAAEAAYEEMWALDVSAMAAYHSGASA
VAVALPAFALPLRLPAGLAAGPAAVVTALTTAVGMPTFAGRAIAASLGLANVGGGNLGNANNGLGNIGNANLGNNNLGSG
NFGSFNIGSANLGGNNIGIGNAGANNFGLANLGNLNTGFANAGIGNFGIANTGNNNIGNGLTGNNQIGIGGLNSGNGNVG
LFNAGSANIGFFNSGNGNFGIGNSGNFSTGLFNPGHGNTGFLNAGSFNTGMFDVGNANTGSFNVGHYNFGAFNPGPSNTG
TFNTGGANTGWFNTGSINTGAFNIGDMNNGLFNTGDMNNGVFYRGVGQGSLQFAITSPDLTLPSLEIPGISVPAFSLPAI
TLPSLTIPAVTTPANVTVGAFDLPGLTVPSLTIPAAMTPANITVGAFDLPGLTVPSLTIPATTTPANITVGAFNLPQLSI
PSVTFPPITIPAGTALGAFNLPTLSIPSVTVPPITIPAGNHCRRIYATHDTHPVNKYTPNKYRRL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002989
- InterPro:   IPR000030 [H]

Pfam domain/function: PF01469 Pentapeptide_2; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 62020; Mature: 62020

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYSVLPPEINSALIFAGAGSGPMLAAASAWDGLATELASAAVSFGSVTAGLVGGSWQGR
CCCCCCCCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCC
SSVAMAAAAAPYAGWLAAAATQAEQAATQAQVMVAEFEAVRLAMVQPALVAANRSGLISL
CCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHCCEEEECCCCCHHHH
VISNLFGQNAPAIAAAEAAYEEMWALDVSAMAAYHSGASAVAVALPAFALPLRLPAGLAA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCC
GPAAVVTALTTAVGMPTFAGRAIAASLGLANVGGGNLGNANNGLGNIGNANLGNNNLGSG
CHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NFGSFNIGSANLGGNNIGIGNAGANNFGLANLGNLNTGFANAGIGNFGIANTGNNNIGNG
CCCCEECCCCCCCCCEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LTGNNQIGIGGLNSGNGNVGLFNAGSANIGFFNSGNGNFGIGNSGNFSTGLFNPGHGNTG
CCCCCEEEECCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
FLNAGSFNTGMFDVGNANTGSFNVGHYNFGAFNPGPSNTGTFNTGGANTGWFNTGSINTG
EEECCCCCCCEEECCCCCCCCEECCEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCC
AFNIGDMNNGLFNTGDMNNGVFYRGVGQGSLQFAITSPDLTLPSLEIPGISVPAFSLPAI
EEECCCCCCCCEECCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCE
TLPSLTIPAVTTPANVTVGAFDLPGLTVPSLTIPAAMTPANITVGAFDLPGLTVPSLTIP
ECCCEEECEECCCCCEEEEEEECCCCCCCCEECCCCCCCCCEEEEEECCCCCCCCCEEEC
ATTTPANITVGAFNLPQLSIPSVTFPPITIPAGTALGAFNLPTLSIPSVTVPPITIPAGN
CCCCCCEEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCC
HCRRIYATHDTHPVNKYTPNKYRRL
CEEEEEEECCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MHYSVLPPEINSALIFAGAGSGPMLAAASAWDGLATELASAAVSFGSVTAGLVGGSWQGR
CCCCCCCCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCC
SSVAMAAAAAPYAGWLAAAATQAEQAATQAQVMVAEFEAVRLAMVQPALVAANRSGLISL
CCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHCCEEEECCCCCHHHH
VISNLFGQNAPAIAAAEAAYEEMWALDVSAMAAYHSGASAVAVALPAFALPLRLPAGLAA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCC
GPAAVVTALTTAVGMPTFAGRAIAASLGLANVGGGNLGNANNGLGNIGNANLGNNNLGSG
CHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NFGSFNIGSANLGGNNIGIGNAGANNFGLANLGNLNTGFANAGIGNFGIANTGNNNIGNG
CCCCEECCCCCCCCCEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LTGNNQIGIGGLNSGNGNVGLFNAGSANIGFFNSGNGNFGIGNSGNFSTGLFNPGHGNTG
CCCCCEEEECCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
FLNAGSFNTGMFDVGNANTGSFNVGHYNFGAFNPGPSNTGTFNTGGANTGWFNTGSINTG
EEECCCCCCCEEECCCCCCCCEECCEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCC
AFNIGDMNNGLFNTGDMNNGVFYRGVGQGSLQFAITSPDLTLPSLEIPGISVPAFSLPAI
EEECCCCCCCCEECCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCE
TLPSLTIPAVTTPANVTVGAFDLPGLTVPSLTIPAAMTPANITVGAFDLPGLTVPSLTIP
ECCCEEECEECCCCCEEEEEEECCCCCCCCEECCCCCCCCCEEEEEECCCCCCCCCEEEC
ATTTPANITVGAFNLPQLSIPSVTFPPITIPAGTALGAFNLPTLSIPSVTVPPITIPAGN
CCCCCCEEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCC
HCRRIYATHDTHPVNKYTPNKYRRL
CEEEEEEECCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]