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The map label for this gene is lldD2 [H]

Identifier: 121637775

GI number: 121637775

Start: 2122866

End: 2124110

Strand: Reverse

Name: lldD2 [H]

Synonym: BCG_1908c

Alternate gene names: 121637775

Gene position: 2124110-2122866 (Counterclockwise)

Preceding gene: 121637784

Following gene: 121637774

Centisome position: 48.56

GC content: 66.35

Gene sequence:

>1245_bases
ATGGCGGTCAACCGGCGAGTGCCCAGAGTGCGCGATCTGGCACCCCTGCTCCAGTTCAACAGGCCGCAGTTCGACACCTC
CAAGCGCCGCCTGGGCGCCGCGCTGACCATCCAGGACCTGCGACGCATTGCCAAACGGCGTACCCCTAGGGCGGCGTTCG
ACTACGCCGACGGGGCTGCCGAGGACGAACTGTCCATCGCGCGTGCTCGACAAGGGTTCCGCGACATCGAGTTTCACCCG
ACAATCCTGCGTGACGTCACCACCGTGTGCGCCGGCTGGAACGTCCTCGGTCAGCCCACCGTCTTGCCATTCGGGATCGC
GCCAACCGGGTTCACCCGCTTGATGCACACCGAGGGCGAGATCGCCGGCGCGCGGGCGGCGGCCGCGGCTGGGATCCCGT
TTTCGCTATCCACCCTGGCCACCTGTGCCATCGAAGACCTCGTCATCGCTGTGCCGCAGGGCCGCAAATGGTTCCAGCTG
TATATGTGGCGTGATCGAGACCGCTCGATGGCATTGGTGCGGCGCGCCGCCGCCGCGGGATTTGACACCATGCTGGTCAC
GGTCGACGTCCCGGTCGCCGGTGCCCGGCTACGCGATGTCCGCAACGGGATGTCCATCCCGCCGGCGCTGACGCTGCGAA
CCGTTCTCGACGCGATGGGACACCCGCGGTGGTGGTTCGACTTGTTGACCACCGAACCGCTGGCCTTCGCTTCACTGGAT
CGCTGGCCTGGCACCGTCGGCGAGTACTTGAACACCGTGTTCGACCCCAGCCTCACCTTCGACGATTTGGCCTGGATCAA
GTCGCAGTGGCCGGGCAAGCTCGTTGTCAAAGGGATCCAAACACTCGACGACGCCCGCGCCGTGGTGGACCGCGGCGTCG
ACGGCATCGTGTTGTCCAATCACGGCGGCCGCCAGCTTGACCGAGCCCCGGTACCCTTCCACCTGTTGCCCCACGTGGCA
CGCGAACTGGGCAAACACACCGAAATCCTGGTGGACACCGGCATCATGTCGGGCGCCGATATCGTCGCGGCGATCGCGTT
GGGGGCACGGTGCACGCTGATCGGGCGGGCCTACCTTTACGGGCTGATGGCCGGTGGTGAGGCGGGCGTCAACCGCGCGA
TCGAGATCCTTCAGACAGGTGTGATCCGGACCATGCGGCTACTGGGCGTGACCTGCCTTGAGGAGCTGTCACCTCGGCAC
GTGACACAACTGCGGCGGCTCGGCCCTATCGGGGCACCAACGTGA

Upstream 100 bases:

>100_bases
CTCGACGACGCTGCGGTAGACCGGAGCCTGCGCGTACACGAAACGCTTCAGGTCGAACGGGTCGCTTGCTGACTTCATAT
CACACTGGTTAGATAAACGG

Downstream 100 bases:

>100_bases
GGCCGCGGCCAGATCGGTAGCGTTGAATGCAGCTATGAATCTCAAGCGGGAATTCGTCCATCGCGTGCAACGGTTCGTGG
TCAATCCAATCGGCCGGCAA

Product: putative L-lactate dehydrogenase (cytochrome) lldD2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MAVNRRVPRVRDLAPLLQFNRPQFDTSKRRLGAALTIQDLRRIAKRRTPRAAFDYADGAAEDELSIARARQGFRDIEFHP
TILRDVTTVCAGWNVLGQPTVLPFGIAPTGFTRLMHTEGEIAGARAAAAAGIPFSLSTLATCAIEDLVIAVPQGRKWFQL
YMWRDRDRSMALVRRAAAAGFDTMLVTVDVPVAGARLRDVRNGMSIPPALTLRTVLDAMGHPRWWFDLLTTEPLAFASLD
RWPGTVGEYLNTVFDPSLTFDDLAWIKSQWPGKLVVKGIQTLDDARAVVDRGVDGIVLSNHGGRQLDRAPVPFHLLPHVA
RELGKHTEILVDTGIMSGADIVAAIALGARCTLIGRAYLYGLMAGGEAGVNRAIEILQTGVIRTMRLLGVTCLEELSPRH
VTQLRRLGPIGAPT

Sequences:

>Translated_414_residues
MAVNRRVPRVRDLAPLLQFNRPQFDTSKRRLGAALTIQDLRRIAKRRTPRAAFDYADGAAEDELSIARARQGFRDIEFHP
TILRDVTTVCAGWNVLGQPTVLPFGIAPTGFTRLMHTEGEIAGARAAAAAGIPFSLSTLATCAIEDLVIAVPQGRKWFQL
YMWRDRDRSMALVRRAAAAGFDTMLVTVDVPVAGARLRDVRNGMSIPPALTLRTVLDAMGHPRWWFDLLTTEPLAFASLD
RWPGTVGEYLNTVFDPSLTFDDLAWIKSQWPGKLVVKGIQTLDDARAVVDRGVDGIVLSNHGGRQLDRAPVPFHLLPHVA
RELGKHTEILVDTGIMSGADIVAAIALGARCTLIGRAYLYGLMAGGEAGVNRAIEILQTGVIRTMRLLGVTCLEELSPRH
VTQLRRLGPIGAPT
>Mature_413_residues
AVNRRVPRVRDLAPLLQFNRPQFDTSKRRLGAALTIQDLRRIAKRRTPRAAFDYADGAAEDELSIARARQGFRDIEFHPT
ILRDVTTVCAGWNVLGQPTVLPFGIAPTGFTRLMHTEGEIAGARAAAAAGIPFSLSTLATCAIEDLVIAVPQGRKWFQLY
MWRDRDRSMALVRRAAAAGFDTMLVTVDVPVAGARLRDVRNGMSIPPALTLRTVLDAMGHPRWWFDLLTTEPLAFASLDR
WPGTVGEYLNTVFDPSLTFDDLAWIKSQWPGKLVVKGIQTLDDARAVVDRGVDGIVLSNHGGRQLDRAPVPFHLLPHVAR
ELGKHTEILVDTGIMSGADIVAAIALGARCTLIGRAYLYGLMAGGEAGVNRAIEILQTGVIRTMRLLGVTCLEELSPRHV
TQLRRLGPIGAPT

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=357, Percent_Identity=33.8935574229692, Blast_Score=225, Evalue=7e-59,
Organism=Homo sapiens, GI54234014, Length=374, Percent_Identity=33.9572192513369, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI7705393, Length=374, Percent_Identity=33.9572192513369, Blast_Score=215, Evalue=6e-56,
Organism=Escherichia coli, GI1790033, Length=373, Percent_Identity=37.2654155495979, Blast_Score=240, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI193208036, Length=372, Percent_Identity=34.1397849462366, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI32566217, Length=283, Percent_Identity=34.2756183745583, Blast_Score=165, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6323587, Length=382, Percent_Identity=31.151832460733, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI78707188, Length=378, Percent_Identity=34.1269841269841, Blast_Score=231, Evalue=6e-61,
Organism=Drosophila melanogaster, GI281363140, Length=378, Percent_Identity=34.1269841269841, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI78707190, Length=378, Percent_Identity=34.1269841269841, Blast_Score=231, Evalue=8e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 45328; Mature: 45197

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVNRRVPRVRDLAPLLQFNRPQFDTSKRRLGAALTIQDLRRIAKRRTPRAAFDYADGAA
CCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHEEHHHHHHHHHHCCCCCHHCCCCCCC
EDELSIARARQGFRDIEFHPTILRDVTTVCAGWNVLGQPTVLPFGIAPTGFTRLMHTEGE
CHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHCCCC
IAGARAAAAAGIPFSLSTLATCAIEDLVIAVPQGRKWFQLYMWRDRDRSMALVRRAAAAG
HHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCCEEEEEEEECCCHHHHHHHHHHHCC
FDTMLVTVDVPVAGARLRDVRNGMSIPPALTLRTVLDAMGHPRWWFDLLTTEPLAFASLD
CCEEEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEHHHHHCCCHHHHHHH
RWPGTVGEYLNTVFDPSLTFDDLAWIKSQWPGKLVVKGIQTLDDARAVVDRGVDGIVLSN
CCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
HGGRQLDRAPVPFHLLPHVARELGKHTEILVDTGIMSGADIVAAIALGARCTLIGRAYLY
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHH
GLMAGGEAGVNRAIEILQTGVIRTMRLLGVTCLEELSPRHVTQLRRLGPIGAPT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AVNRRVPRVRDLAPLLQFNRPQFDTSKRRLGAALTIQDLRRIAKRRTPRAAFDYADGAA
CCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHEEHHHHHHHHHHCCCCCHHCCCCCCC
EDELSIARARQGFRDIEFHPTILRDVTTVCAGWNVLGQPTVLPFGIAPTGFTRLMHTEGE
CHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHCCCC
IAGARAAAAAGIPFSLSTLATCAIEDLVIAVPQGRKWFQLYMWRDRDRSMALVRRAAAAG
HHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCCEEEEEEEECCCHHHHHHHHHHHCC
FDTMLVTVDVPVAGARLRDVRNGMSIPPALTLRTVLDAMGHPRWWFDLLTTEPLAFASLD
CCEEEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEHHHHHCCCHHHHHHH
RWPGTVGEYLNTVFDPSLTFDDLAWIKSQWPGKLVVKGIQTLDDARAVVDRGVDGIVLSN
CCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
HGGRQLDRAPVPFHLLPHVARELGKHTEILVDTGIMSGADIVAAIALGARCTLIGRAYLY
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHH
GLMAGGEAGVNRAIEILQTGVIRTMRLLGVTCLEELSPRHVTQLRRLGPIGAPT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]