Click here to switch to the map view.

The map label for this gene is ychM [C]

Identifier: 121637647

GI number: 121637647

Start: 1971114

End: 1972796

Strand: Reverse

Name: ychM [C]

Synonym: BCG_1778c

Alternate gene names: 121637647

Gene position: 1972796-1971114 (Counterclockwise)

Preceding gene: 121637652

Following gene: 121637645

Centisome position: 45.1

GC content: 62.8

Gene sequence:

>1683_bases
ATGATTCCCACGATGACATCGGCCGGCTGGGCACCAGGGGTGGTGCAGTTCCGCGAATACCAACGGCGTTGGCTGCGCGG
CGATGTCCTCGCCGGCCTGACCGTGGCCGCCTATCTGATCCCGCAAGCGATGGCGTATGCGACCGTGGCGGGCCTACCGC
CGGCAGCCGGGCTGTGGGCGTCGATCGCGCCGCTTGCCATTTACGCACTGCTCGGATCGTCCCGGCAGCTTTCAATCGGC
CCGGAATCCGCCACCGCCTTGATGACGGCGGCCGTGCTCGCTCCGATGGCCGCCGGGGATCTTCGACGCTATGCCGTTCT
GGCGGCAACCCTCGGATTGCTAGTCGGCCTTATCTGCCTACTCGCTGGCACGGCGCGACTAGGTTTCCTCGCCAGCCTGC
TATCGCGGCCGGTGCTCGTCGGATACATGGCCGGCATCGCGCTTGTCATGATCTCCAGCCAACTCGGCACTATCACCGGC
ACCTCGGTCGAAGGCAACGAATTCTTCAGCGAAGTACACTCTTTCGCGACTAGCGTCACGCGAGTTCACTGGCCGACTTT
TGTGTTAGCCATGTCTGTCCTAGCGCTGCTAACTATGCTCACGCGGTGGGCGCCGCGCGCCCCCGGACCGATCATCGCGG
TTCTTGCGGCCACGATGCTAGTGGCCGTTATGTCCTTGGATGCCAAAGGTATTGCGATTGTGGGTCGGATACCTTCCGGT
CTGCCGACGCCGGGTGTGCCGCCCGTTTCGGTGGAAGACTTGCGGGCACTGATCATTCCGGCTGCCGGGATCGCGATTGT
TACCTTCACCGACGGTGTGTTGACCGCACGCGCCTTCGCCGCTCGTCGAGGTCAGGAAGTCAATGCCAACGCCGAGCTGC
GCGCGGTCGGGGCCTGCAACATCGCCGCCGGGCTGACACACGGTTTTCCGGTGAGTTCCAGCAGCAGCCGTACCGCCCTC
GCCGACGTCGTCGGTGGCCGCACCCAGCTGTACTCGCTGATCGCGTTGGGGCTTGTTGTCATCGTGATGGTTTTCGCGAG
TGGGCTGCTGGCCATGTTTCCGATCGCCGCTCTGGGCGCTTTGGTGGTATATGCCGCGCTACGCTTGATCGACTTGTCAG
AATTCCGGCGACTGGCGCGGTTTCGGCGCAGCGAACTCATGCTGGCACTAGCCACCACAGCAGCCGTGTTAGGCCTAGGA
GTGTTCTATGGAGTCCTCGCCGCGGTTGCCCTGTCCATCCTCGAACTGCTTCGTCGGGTCGCACATCCGCATGACAGCGT
TCTCGGGTTCGTGCCGGGCATTGCCGGCATGCACGACATCGATGACTATCCGCAGGCCAAGCGCGTGCCCGGGCTGGTGG
TGTATCGCTATGACGCGCCGTTGTGCTTCGCCAATGCCGAAGACTTCCGCAGGCGAGCACTGACCGTGGTCGATCAGGAT
CCGGGGCAAGTCGAGTGGTTCGTACTCAACGCCGAATCCAATGTGGAGGTCGACCTGACTGCGCTGGATGCGCTCGACCA
ACTCCGCACCGAGCTGCTGCGTCGGGGAATAGTGTTCGCCATGGCCCGGGTCAAACAAGACTTGCGTGAATCACTCAGGG
CCGCCAGTCTTCTCGATAAGATTGGCGAAGACCATATCTTTATGACATTGCCTACCGCAGTGCAGGCGTTCCGTCGGCGC
TAA

Upstream 100 bases:

>100_bases
CAAAGTCTCGCCCATTCGAGCCGCCAATTCCATGGTCAGGATTCTATAAAGATTGGGCGGGTTCTAGACCGACTCTAGCT
AAGCGGCCAGCCGTCGGACA

Downstream 100 bases:

>100_bases
CGCGCCGGCACCCTCAATACAACAATCGCGCCGGCTGATGGGTAACAGCTTCGATGTCGTGGGTCGACACCTTCAACATT
CGCTTCCCCAAGTCGGACAA

Product: putative sulphate-transport transmembrane protein ABC transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MIPTMTSAGWAPGVVQFREYQRRWLRGDVLAGLTVAAYLIPQAMAYATVAGLPPAAGLWASIAPLAIYALLGSSRQLSIG
PESATALMTAAVLAPMAAGDLRRYAVLAATLGLLVGLICLLAGTARLGFLASLLSRPVLVGYMAGIALVMISSQLGTITG
TSVEGNEFFSEVHSFATSVTRVHWPTFVLAMSVLALLTMLTRWAPRAPGPIIAVLAATMLVAVMSLDAKGIAIVGRIPSG
LPTPGVPPVSVEDLRALIIPAAGIAIVTFTDGVLTARAFAARRGQEVNANAELRAVGACNIAAGLTHGFPVSSSSSRTAL
ADVVGGRTQLYSLIALGLVVIVMVFASGLLAMFPIAALGALVVYAALRLIDLSEFRRLARFRRSELMLALATTAAVLGLG
VFYGVLAAVALSILELLRRVAHPHDSVLGFVPGIAGMHDIDDYPQAKRVPGLVVYRYDAPLCFANAEDFRRRALTVVDQD
PGQVEWFVLNAESNVEVDLTALDALDQLRTELLRRGIVFAMARVKQDLRESLRAASLLDKIGEDHIFMTLPTAVQAFRRR

Sequences:

>Translated_560_residues
MIPTMTSAGWAPGVVQFREYQRRWLRGDVLAGLTVAAYLIPQAMAYATVAGLPPAAGLWASIAPLAIYALLGSSRQLSIG
PESATALMTAAVLAPMAAGDLRRYAVLAATLGLLVGLICLLAGTARLGFLASLLSRPVLVGYMAGIALVMISSQLGTITG
TSVEGNEFFSEVHSFATSVTRVHWPTFVLAMSVLALLTMLTRWAPRAPGPIIAVLAATMLVAVMSLDAKGIAIVGRIPSG
LPTPGVPPVSVEDLRALIIPAAGIAIVTFTDGVLTARAFAARRGQEVNANAELRAVGACNIAAGLTHGFPVSSSSSRTAL
ADVVGGRTQLYSLIALGLVVIVMVFASGLLAMFPIAALGALVVYAALRLIDLSEFRRLARFRRSELMLALATTAAVLGLG
VFYGVLAAVALSILELLRRVAHPHDSVLGFVPGIAGMHDIDDYPQAKRVPGLVVYRYDAPLCFANAEDFRRRALTVVDQD
PGQVEWFVLNAESNVEVDLTALDALDQLRTELLRRGIVFAMARVKQDLRESLRAASLLDKIGEDHIFMTLPTAVQAFRRR
>Mature_560_residues
MIPTMTSAGWAPGVVQFREYQRRWLRGDVLAGLTVAAYLIPQAMAYATVAGLPPAAGLWASIAPLAIYALLGSSRQLSIG
PESATALMTAAVLAPMAAGDLRRYAVLAATLGLLVGLICLLAGTARLGFLASLLSRPVLVGYMAGIALVMISSQLGTITG
TSVEGNEFFSEVHSFATSVTRVHWPTFVLAMSVLALLTMLTRWAPRAPGPIIAVLAATMLVAVMSLDAKGIAIVGRIPSG
LPTPGVPPVSVEDLRALIIPAAGIAIVTFTDGVLTARAFAARRGQEVNANAELRAVGACNIAAGLTHGFPVSSSSSRTAL
ADVVGGRTQLYSLIALGLVVIVMVFASGLLAMFPIAALGALVVYAALRLIDLSEFRRLARFRRSELMLALATTAAVLGLG
VFYGVLAAVALSILELLRRVAHPHDSVLGFVPGIAGMHDIDDYPQAKRVPGLVVYRYDAPLCFANAEDFRRRALTVVDQD
PGQVEWFVLNAESNVEVDLTALDALDQLRTELLRRGIVFAMARVKQDLRESLRAASLLDKIGEDHIFMTLPTAVQAFRRR

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=492, Percent_Identity=30.0813008130081, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI39752683, Length=492, Percent_Identity=30.0813008130081, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI94721255, Length=477, Percent_Identity=33.7526205450734, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI94721259, Length=477, Percent_Identity=33.7526205450734, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI94721253, Length=477, Percent_Identity=33.7526205450734, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI94721257, Length=477, Percent_Identity=33.7526205450734, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI269784651, Length=487, Percent_Identity=28.5420944558522, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI45827802, Length=449, Percent_Identity=29.6213808463252, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI4557535, Length=513, Percent_Identity=26.9005847953216, Blast_Score=159, Evalue=9e-39,
Organism=Homo sapiens, GI262206105, Length=586, Percent_Identity=27.8156996587031, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI262206075, Length=586, Percent_Identity=27.8156996587031, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI262206069, Length=586, Percent_Identity=27.8156996587031, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI262206063, Length=586, Percent_Identity=27.8156996587031, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI4505697, Length=500, Percent_Identity=25.8, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI47131207, Length=517, Percent_Identity=29.0135396518375, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI20336272, Length=517, Percent_Identity=29.0135396518375, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI100913030, Length=620, Percent_Identity=23.5483870967742, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI16418413, Length=545, Percent_Identity=25.3211009174312, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI217272867, Length=545, Percent_Identity=25.5045871559633, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI16418457, Length=493, Percent_Identity=22.5152129817444, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI301601599, Length=493, Percent_Identity=22.5152129817444, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI20336282, Length=510, Percent_Identity=22.156862745098, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI16306483, Length=510, Percent_Identity=22.156862745098, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI65506789, Length=386, Percent_Identity=27.979274611399, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI45827804, Length=263, Percent_Identity=27.7566539923954, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI301601602, Length=291, Percent_Identity=22.680412371134, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI87081859, Length=512, Percent_Identity=23.6328125, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17551690, Length=582, Percent_Identity=25.4295532646048, Blast_Score=161, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17566848, Length=556, Percent_Identity=25.7194244604317, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17562578, Length=634, Percent_Identity=23.9747634069401, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI86564196, Length=631, Percent_Identity=24.0887480190174, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI193203292, Length=486, Percent_Identity=27.1604938271605, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI86565215, Length=557, Percent_Identity=24.7755834829443, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI86564876, Length=648, Percent_Identity=22.2222222222222, Blast_Score=125, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI86565213, Length=246, Percent_Identity=25.609756097561, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI86565209, Length=240, Percent_Identity=23.75, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI86565211, Length=240, Percent_Identity=23.75, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325260, Length=584, Percent_Identity=22.7739726027397, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6319771, Length=470, Percent_Identity=26.1702127659574, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323121, Length=479, Percent_Identity=27.1398747390397, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24649801, Length=457, Percent_Identity=27.3522975929978, Blast_Score=168, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24666186, Length=529, Percent_Identity=26.0869565217391, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI19922482, Length=567, Percent_Identity=24.5149911816578, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24651449, Length=461, Percent_Identity=27.5488069414317, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI21358229, Length=457, Percent_Identity=26.6958424507659, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI85815873, Length=440, Percent_Identity=27.2727272727273, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24647160, Length=440, Percent_Identity=25.9090909090909, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI21355087, Length=440, Percent_Identity=25.9090909090909, Blast_Score=122, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24663084, Length=544, Percent_Identity=25.9191176470588, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357695, Length=544, Percent_Identity=25.9191176470588, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21358633, Length=531, Percent_Identity=22.7871939736347, Blast_Score=108, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 59325; Mature: 59325

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50801 STAS ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPTMTSAGWAPGVVQFREYQRRWLRGDVLAGLTVAAYLIPQAMAYATVAGLPPAAGLWA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SIAPLAIYALLGSSRQLSIGPESATALMTAAVLAPMAAGDLRRYAVLAATLGLLVGLICL
HHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGTARLGFLASLLSRPVLVGYMAGIALVMISSQLGTITGTSVEGNEFFSEVHSFATSVT
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHH
RVHWPTFVLAMSVLALLTMLTRWAPRAPGPIIAVLAATMLVAVMSLDAKGIAIVGRIPSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
LPTPGVPPVSVEDLRALIIPAAGIAIVTFTDGVLTARAFAARRGQEVNANAELRAVGACN
CCCCCCCCCCHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCEEEEECCH
IAAGLTHGFPVSSSSSRTALADVVGGRTQLYSLIALGLVVIVMVFASGLLAMFPIAALGA
HHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVVYAALRLIDLSEFRRLARFRRSELMLALATTAAVLGLGVFYGVLAAVALSILELLRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHPHDSVLGFVPGIAGMHDIDDYPQAKRVPGLVVYRYDAPLCFANAEDFRRRALTVVDQD
CCCCHHHHHHHCCCCCCCCCCCCCCHHCCCCEEEEEECCCEEECCHHHHHHHHHEEEECC
PGQVEWFVLNAESNVEVDLTALDALDQLRTELLRRGIVFAMARVKQDLRESLRAASLLDK
CCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGEDHIFMTLPTAVQAFRRR
HCCCCEEEECHHHHHHHHCC
>Mature Secondary Structure
MIPTMTSAGWAPGVVQFREYQRRWLRGDVLAGLTVAAYLIPQAMAYATVAGLPPAAGLWA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SIAPLAIYALLGSSRQLSIGPESATALMTAAVLAPMAAGDLRRYAVLAATLGLLVGLICL
HHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGTARLGFLASLLSRPVLVGYMAGIALVMISSQLGTITGTSVEGNEFFSEVHSFATSVT
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHH
RVHWPTFVLAMSVLALLTMLTRWAPRAPGPIIAVLAATMLVAVMSLDAKGIAIVGRIPSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
LPTPGVPPVSVEDLRALIIPAAGIAIVTFTDGVLTARAFAARRGQEVNANAELRAVGACN
CCCCCCCCCCHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCEEEEECCH
IAAGLTHGFPVSSSSSRTALADVVGGRTQLYSLIALGLVVIVMVFASGLLAMFPIAALGA
HHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVVYAALRLIDLSEFRRLARFRRSELMLALATTAAVLGLGVFYGVLAAVALSILELLRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHPHDSVLGFVPGIAGMHDIDDYPQAKRVPGLVVYRYDAPLCFANAEDFRRRALTVVDQD
CCCCHHHHHHHCCCCCCCCCCCCCCHHCCCCEEEEEECCCEEECCHHHHHHHHHEEEECC
PGQVEWFVLNAESNVEVDLTALDALDQLRTELLRRGIVFAMARVKQDLRESLRAASLLDK
CCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGEDHIFMTLPTAVQAFRRR
HCCCCEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]