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The map label for this gene is tal

Identifier: 121637378

GI number: 121637378

Start: 1651771

End: 1652892

Strand: Reverse

Name: tal

Synonym: BCG_1509c

Alternate gene names: 121637378

Gene position: 1652892-1651771 (Counterclockwise)

Preceding gene: 121637379

Following gene: 121637377

Centisome position: 37.78

GC content: 64.26

Gene sequence:

>1122_bases
ATGACCGCTCAGAACCCCAACCTGGCCGCATTGAGCGCCGCGGGGGTATCGGTGTGGCTGGATGACCTGTCGCGGGACCG
GCTGCGCTCGGGCAATCTGCAGGAGCTGATCGACACCAAGAGCGTCGTCGGGGTGACCACCAACCCGTCGATCTTTCAGA
AGGCGCTGTCGGAGGGCCACACCTACGACGCCCAGATCGCCGAGCTGGCCGCGCGCGGCGCCGACGTGGATGCCACCATC
CGCACCGTCACCACTGACGACGTGCGCAGCGCGTGCGACGTGCTGGTCCCCCAGTGGGAGGACTCCGACGGGGTCGACGG
CCGGGTGTCGATCGAGGTCGACCCGCGGCTGGCACACGAAACCGAAAAAACGATCCAACAGGCAATCGAGCTGTGGAAGA
TCGTCGACCGGCCGAACCTTTTCATCAAGATCCCGGCCACTAAGGCCGGTCTGCCCGCCATCAGTGCCGTTCTGGCGGAA
GGGATTTCGGTCAACGTTACGCTGATCTTCTCCGTGCAGCGGTACCGCGAGGTGATGGACGCCTACCTGACCGGGATGGA
AAAGGCCCGGCAAGCCGGACACAGCCTGTCCAAGATCCATTCGGTGGCATCGTTTTTCGTCTCCCGGGTGGACACCGAAA
TCGACAAGCGGCTGGACAGAATCGGCTCGCGGCAAGCGCTCGAACTGCGCGGCCAGGCCGGTGTCGCCAATGCCCGCCTG
GCCTATGCCGCCTACCGGGAGGTCTTCGAAGACAGCGATCGTTATCGGTCCCTCAAGGTCGACGGCGCCCGGGTCCAGCG
CCCGTTGTGGGCTTCCACCGGCGTGAAGAACCCCGATTACTCGGACACCCTCTACGTCACCGAGTTGGTCGCCCCACACA
CCGTGAACACTATGCCGGAAAAGACAATTGACGCCGTCGCTGATCATGGCGTGATCCAAGGCGACACGGTCACCGGAACT
GCATCCGATGCCCAGGCGGTGTTCGACCAGCTGGGGGCGATCGGCATCGACCTCACCGACGTGTTTGCCGTCCTCGAGGA
GGAAGGCGTGCGGAAGTTCGAGGCCTCCTGGAACGAGCTACTCCAGGAAACCCGGGCGCATCTCGACACCGCTGCCCAAT
GA

Upstream 100 bases:

>100_bases
GCGGACCACAAGACCTTGTTCCGCGAGTACGGCTTCACTGCCGAGGCCGTGGCCGCCGCCGCCGAACGAGCGCTGGATAA
CTGAGGAAGGGTGATTACCG

Downstream 100 bases:

>100_bases
AACCGGCCCACGCCGCGGCGTCGTGGCGCAACCCGCTACGAGACAAGCGGGACAAGCGATTACCCAGAATCGCCGGCCCG
TGCGGCATGGTGATTTTCGG

Product: transaldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MTAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTNPSIFQKALSEGHTYDAQIAELAARGADVDATI
RTVTTDDVRSACDVLVPQWEDSDGVDGRVSIEVDPRLAHETEKTIQQAIELWKIVDRPNLFIKIPATKAGLPAISAVLAE
GISVNVTLIFSVQRYREVMDAYLTGMEKARQAGHSLSKIHSVASFFVSRVDTEIDKRLDRIGSRQALELRGQAGVANARL
AYAAYREVFEDSDRYRSLKVDGARVQRPLWASTGVKNPDYSDTLYVTELVAPHTVNTMPEKTIDAVADHGVIQGDTVTGT
ASDAQAVFDQLGAIGIDLTDVFAVLEEEGVRKFEASWNELLQETRAHLDTAAQ

Sequences:

>Translated_373_residues
MTAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTNPSIFQKALSEGHTYDAQIAELAARGADVDATI
RTVTTDDVRSACDVLVPQWEDSDGVDGRVSIEVDPRLAHETEKTIQQAIELWKIVDRPNLFIKIPATKAGLPAISAVLAE
GISVNVTLIFSVQRYREVMDAYLTGMEKARQAGHSLSKIHSVASFFVSRVDTEIDKRLDRIGSRQALELRGQAGVANARL
AYAAYREVFEDSDRYRSLKVDGARVQRPLWASTGVKNPDYSDTLYVTELVAPHTVNTMPEKTIDAVADHGVIQGDTVTGT
ASDAQAVFDQLGAIGIDLTDVFAVLEEEGVRKFEASWNELLQETRAHLDTAAQ
>Mature_372_residues
TAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTNPSIFQKALSEGHTYDAQIAELAARGADVDATIR
TVTTDDVRSACDVLVPQWEDSDGVDGRVSIEVDPRLAHETEKTIQQAIELWKIVDRPNLFIKIPATKAGLPAISAVLAEG
ISVNVTLIFSVQRYREVMDAYLTGMEKARQAGHSLSKIHSVASFFVSRVDTEIDKRLDRIGSRQALELRGQAGVANARLA
YAAYREVFEDSDRYRSLKVDGARVQRPLWASTGVKNPDYSDTLYVTELVAPHTVNTMPEKTIDAVADHGVIQGDTVTGTA
SDAQAVFDQLGAIGIDLTDVFAVLEEEGVRKFEASWNELLQETRAHLDTAAQ

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 2 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_MYCBO (P59955)

Other databases:

- EMBL:   BX248339
- RefSeq:   NP_855135.1
- ProteinModelPortal:   P59955
- SMR:   P59955
- EnsemblBacteria:   EBMYCT00000014341
- GeneID:   1092340
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1483c
- GeneTree:   EBGT00050000017406
- HOGENOM:   HBG321149
- OMA:   MPEKTLD
- ProtClustDB:   PRK03343
- BioCyc:   MBOV233413:MB1483C-MONOMER
- BRENDA:   2.2.1.2
- GO:   GO:0005737
- HAMAP:   MF_00493
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004732
- InterPro:   IPR018225
- InterPro:   IPR014634
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- PIRSF:   PIRSF036915
- TIGRFAMs:   TIGR00876

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 40691; Mature: 40560

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 143-143

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTNPSIFQKALSEGH
CCCCCCCEEEEHHCCHHHHHHHHHHHHHCCCCHHHHHCCHHEEEECCCHHHHHHHHHCCC
TYDAQIAELAARGADVDATIRTVTTDDVRSACDVLVPQWEDSDGVDGRVSIEVDPRLAHE
CCHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHH
TEKTIQQAIELWKIVDRPNLFIKIPATKAGLPAISAVLAEGISVNVTLIFSVQRYREVMD
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEEEEEHHHHHHHHH
AYLTGMEKARQAGHSLSKIHSVASFFVSRVDTEIDKRLDRIGSRQALELRGQAGVANARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHH
AYAAYREVFEDSDRYRSLKVDGARVQRPLWASTGVKNPDYSDTLYVTELVAPHTVNTMPE
HHHHHHHHHHCCHHHEEEECCHHHHCCCCHHCCCCCCCCCCCCEEEEHHHCCCCCCCCCH
KTIDAVADHGVIQGDTVTGTASDAQAVFDQLGAIGIDLTDVFAVLEEEGVRKFEASWNEL
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LQETRAHLDTAAQ
HHHHHHHHHHCCC
>Mature Secondary Structure 
TAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTNPSIFQKALSEGH
CCCCCCEEEEHHCCHHHHHHHHHHHHHCCCCHHHHHCCHHEEEECCCHHHHHHHHHCCC
TYDAQIAELAARGADVDATIRTVTTDDVRSACDVLVPQWEDSDGVDGRVSIEVDPRLAHE
CCHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHH
TEKTIQQAIELWKIVDRPNLFIKIPATKAGLPAISAVLAEGISVNVTLIFSVQRYREVMD
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEEEEEHHHHHHHHH
AYLTGMEKARQAGHSLSKIHSVASFFVSRVDTEIDKRLDRIGSRQALELRGQAGVANARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHH
AYAAYREVFEDSDRYRSLKVDGARVQRPLWASTGVKNPDYSDTLYVTELVAPHTVNTMPE
HHHHHHHHHHCCHHHEEEECCHHHHCCCCHHCCCCCCCCCCCCEEEEHHHCCCCCCCCCH
KTIDAVADHGVIQGDTVTGTASDAQAVFDQLGAIGIDLTDVFAVLEEEGVRKFEASWNEL
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LQETRAHLDTAAQ
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972