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The map label for this gene is PPE18 [H]

Identifier: 121637125

GI number: 121637125

Start: 1369071

End: 1370243

Strand: Direct

Name: PPE18 [H]

Synonym: BCG_1256

Alternate gene names: 121637125

Gene position: 1369071-1370243 (Clockwise)

Preceding gene: 121637124

Following gene: 121637126

Centisome position: 31.3

GC content: 68.37

Gene sequence:

>1173_bases
ATGGTGGATTTCGGGGCGTTACCACCGGAGATCAACTCCGCGAGGATGTACGCCGGCCCGGGTTCGGCCTCGCTGGTGGC
CGCCGCGAAGATGTGGGACAGCGTGGCGAGTGACCTGTTTTCGGCCGCGTCGGCGTTTCAGTCGGTGGTCTGGGGTCTGA
CGGTGGGGTCGTGGATAGGTTCGTCGGCGGGTCTGATGGTGGCGGCGGCCTCGCCGTATGTGGCGTGGATGAGCGTCACC
GCGGGGCAGGCCGAGCTGACCGCCGCCCAGGTCCGGGTTGCTGCGGCGGCCTACGAGACGGCGTATGGGCTGACGGTGCC
CCCGCCGGTGATCGCCGAGAACCGTGCTGAACTGATGATTCTGACCGCGACCAACCTCTTGGGGCAAAACACCCCGGCGA
TCGCGGTCAACGAGGCCGAATACGGCGAGATGTGGGCCCAAGACGCCGCCGCGATGTTTGGCTACGCCGCGGCGACGGCG
ACGGCGACGGCGACGTTGCTGCCGTTCGAGGAGGCGCCGGAGATGACCAGCGCGGGTGGGCTCCTTGAGCAGGCCGTCGC
GGTCGAGGAGGCCTCCGACACCGCCGCGGCGAACCAGTTGATGAACAATGTGCCCCAGGCGCTGCAACAACTGGCCCAGC
CCACGAAAAGCATCTGGCCGTTCGACCAACTGAGTGAACTCTGGAAAGCCATCTCGCCGCATCTGTCGCCGCTCAGCAAC
ATCGTGTCGATGCTCAACAACCACGTGTCGATGACCAACTCGGGTGTGTCGATGGCCAGCACCTTGAGCTCGATGTTGAA
GGGCTTTGCTCCGGCGGCGGCTCAGGCCGTGGAAACCGCGGCGCAAAACGGGGTCCGGGCGATGAGCTCGCTGGGCAGCT
CGCTGGGTTCTTCGGGTCTGGGCGGTGGGGTGGCCGCCAACTTGGGTCGGGCGGCCTCGGTCGGTTCGTTGTCGGTGCCG
CCAGCATGGGCCGCGGCCAACCAGGCAGTCACCCCGGCGGCGCGGGCGCTGCCGCTGACCAGCCTGACCAGCGCCGCGGA
AAGAGGGCCCGGGCAGATGCTGGGCGGGCTGCCGGTGGGGCAGATGGGCGCCAGGGCCGGTGGTGGGCTCAGTGGTGTGC
TGCGTGTTCCGCCGCGACCCTATGTGATGCCGCATTCTCCGGCGGCCGGCTAG

Upstream 100 bases:

>100_bases
AGCGCCAGCTCGTATGCGGCCACTGAAGTCGCCAATGCGGCGGCGGCCAGCTAAGCCAGGAACAGTCGGCACGAGAAACC
ACGAGAAATAGGGACACGTA

Downstream 100 bases:

>100_bases
GAGAGGGGGCGCAGACTGTCGTTATTTGACCAGTGATCGGCGGTCTCGGTGTTTCCGCGGCCGGCTATGACAACAGTCAA
TGTGCATGACAAGTTACAGG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MVDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTVGSWIGSSAGLMVAAASPYVAWMSVT
AGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMILTATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAAATA
TATATLLPFEEAPEMTSAGGLLEQAVAVEEASDTAAANQLMNNVPQALQQLAQPTKSIWPFDQLSELWKAISPHLSPLSN
IVSMLNNHVSMTNSGVSMASTLSSMLKGFAPAAAQAVETAAQNGVRAMSSLGSSLGSSGLGGGVAANLGRAASVGSLSVP
PAWAAANQAVTPAARALPLTSLTSAAERGPGQMLGGLPVGQMGARAGGGLSGVLRVPPRPYVMPHSPAAG

Sequences:

>Translated_390_residues
MVDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTVGSWIGSSAGLMVAAASPYVAWMSVT
AGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMILTATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAAATA
TATATLLPFEEAPEMTSAGGLLEQAVAVEEASDTAAANQLMNNVPQALQQLAQPTKSIWPFDQLSELWKAISPHLSPLSN
IVSMLNNHVSMTNSGVSMASTLSSMLKGFAPAAAQAVETAAQNGVRAMSSLGSSLGSSGLGGGVAANLGRAASVGSLSVP
PAWAAANQAVTPAARALPLTSLTSAAERGPGQMLGGLPVGQMGARAGGGLSGVLRVPPRPYVMPHSPAAG
>Mature_390_residues
MVDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTVGSWIGSSAGLMVAAASPYVAWMSVT
AGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMILTATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAAATA
TATATLLPFEEAPEMTSAGGLLEQAVAVEEASDTAAANQLMNNVPQALQQLAQPTKSIWPFDQLSELWKAISPHLSPLSN
IVSMLNNHVSMTNSGVSMASTLSSMLKGFAPAAAQAVETAAQNGVRAMSSLGSSLGSSGLGGGVAANLGRAASVGSLSVP
PAWAAANQAVTPAARALPLTSLTSAAERGPGQMLGGLPVGQMGARAGGGLSGVLRVPPRPYVMPHSPAAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022171
- InterPro:   IPR000030 [H]

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 39267; Mature: 39267

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00501 SPASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTVGSWIG
CCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSAGLMVAAASPYVAWMSVTAGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMI
CCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
LTATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAAATATATATLLPFEEAPEMTSAGG
EEEHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHCCCHHHHHH
LLEQAVAVEEASDTAAANQLMNNVPQALQQLAQPTKSIWPFDQLSELWKAISPHLSPLSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
IVSMLNNHVSMTNSGVSMASTLSSMLKGFAPAAAQAVETAAQNGVRAMSSLGSSLGSSGL
HHHHHHCCHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GGGVAANLGRAASVGSLSVPPAWAAANQAVTPAARALPLTSLTSAAERGPGQMLGGLPVG
CCHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCHHHHCCHHHHHHHHHCCCCHHHCCCCHH
QMGARAGGGLSGVLRVPPRPYVMPHSPAAG
HHCCCCCCCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MVDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTVGSWIG
CCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSAGLMVAAASPYVAWMSVTAGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMI
CCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
LTATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAAATATATATLLPFEEAPEMTSAGG
EEEHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHCCCHHHHHH
LLEQAVAVEEASDTAAANQLMNNVPQALQQLAQPTKSIWPFDQLSELWKAISPHLSPLSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
IVSMLNNHVSMTNSGVSMASTLSSMLKGFAPAAAQAVETAAQNGVRAMSSLGSSLGSSGL
HHHHHHCCHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GGGVAANLGRAASVGSLSVPPAWAAANQAVTPAARALPLTSLTSAAERGPGQMLGGLPVG
CCHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCHHHHCCHHHHHHHHHCCCCHHHCCCCHH
QMGARAGGGLSGVLRVPPRPYVMPHSPAAG
HHCCCCCCCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]