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The map label for this gene is fabG [H]

Identifier: 121637077

GI number: 121637077

Start: 1302571

End: 1303323

Strand: Direct

Name: fabG [H]

Synonym: BCG_1206

Alternate gene names: 121637077

Gene position: 1302571-1303323 (Clockwise)

Preceding gene: 121637076

Following gene: 121637078

Centisome position: 29.78

GC content: 66.8

Gene sequence:

>753_bases
ATGAAGACCAAAGACGCCGTAGCCGTTGTCACCGGTGGCGCCTCAGGCCTGGGTCTGGCCACCACCAAGCGGCTATTGGA
CGCTGGGGCACAGGTGGTCGTCGTGGACCTCCGCGGCGACGACGTGGTTGGCGGGCTCGGCGATCGCGCGCGTTTTGCGC
AAGCCGACGTCACCGACGAAGCCGCCGTCAGCAACGCGCTAGAGCTGGCGGATTCGCTCGGCCCGGTGCGGGTCGTCGTC
AACTGCGCCGGCACCGGCAACGCGATTCGCGTACTGAGTCGCGACGGCGTGTTCCCGCTGGCCGCGTTCCGCAAGATCGT
GGACATCAACCTAGTCGGCACCTTCAACGTGCTGCGACTGGGCGCCGAGCGGATCGCCAAGACCGAACCGATTGGGGAAG
AGCGCGGCGTCATCATTAACACCGCCTCGGTGGCGGCATTCGACGGTCAGATCGGCCAGGCCGCCTACTCGGCGTCCAAG
GGCGGCGTAGTTGGCATGACCCTGCCGATCGCCCGCGATCTGGCCAGCAAGCTGATCCGGGTGGTCACCATTGCGCCGGG
TCTGTTCGACACCCCGCTGCTGGCTTCATTGCCGGCGGAGGCCAAGGCCTCACTGGGCCAACAGGTGCCGCATCCCTCGC
GGCTGGGCAACCCCGACGAGTACGGGGCGCTAGTTCTGCACATCATCGAAAACCCGATGCTTAACGGCGAGGTCATCCGT
CTGGACGGCGCCATCCGCATGGCGCCGCGCTAA

Upstream 100 bases:

>100_bases
CGCGGTTCTCCCGCACCGCTTCGAGCCAGCCACGCCCGCCGGCCGCCACGATCGACATCGAGGCAGTGCTCACCGACTGG
GACGGATAGGAAGGATTCGT

Downstream 100 bases:

>100_bases
GCCGCACCAAAAGAAAGACCCCCGCGTTGCGGGGGACCGGAATCGGGAACAAGAACTTACCGACGAAACCATCGGCTGAC
GGCTGGTTCGGCCATGAGGA

Product: putative short-chain type dehydrogenase/reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVVVDLRGDDVVGGLGDRARFAQADVTDEAAVSNALELADSLGPVRVVV
NCAGTGNAIRVLSRDGVFPLAAFRKIVDINLVGTFNVLRLGAERIAKTEPIGEERGVIINTASVAAFDGQIGQAAYSASK
GGVVGMTLPIARDLASKLIRVVTIAPGLFDTPLLASLPAEAKASLGQQVPHPSRLGNPDEYGALVLHIIENPMLNGEVIR
LDGAIRMAPR

Sequences:

>Translated_250_residues
MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVVVDLRGDDVVGGLGDRARFAQADVTDEAAVSNALELADSLGPVRVVV
NCAGTGNAIRVLSRDGVFPLAAFRKIVDINLVGTFNVLRLGAERIAKTEPIGEERGVIINTASVAAFDGQIGQAAYSASK
GGVVGMTLPIARDLASKLIRVVTIAPGLFDTPLLASLPAEAKASLGQQVPHPSRLGNPDEYGALVLHIIENPMLNGEVIR
LDGAIRMAPR
>Mature_250_residues
MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVVVDLRGDDVVGGLGDRARFAQADVTDEAAVSNALELADSLGPVRVVV
NCAGTGNAIRVLSRDGVFPLAAFRKIVDINLVGTFNVLRLGAERIAKTEPIGEERGVIINTASVAAFDGQIGQAAYSASK
GGVVGMTLPIARDLASKLIRVVTIAPGLFDTPLLASLPAEAKASLGQQVPHPSRLGNPDEYGALVLHIIENPMLNGEVIR
LDGAIRMAPR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=60.0790513833992, Blast_Score=263, Evalue=8e-71,
Organism=Homo sapiens, GI83715985, Length=253, Percent_Identity=57.3122529644269, Blast_Score=244, Evalue=6e-65,
Organism=Homo sapiens, GI40254992, Length=251, Percent_Identity=31.4741035856574, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI15277342, Length=266, Percent_Identity=30.0751879699248, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI31542939, Length=261, Percent_Identity=28.3524904214559, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=30.3149606299213, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI224922801, Length=188, Percent_Identity=30.8510638297872, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI59889578, Length=212, Percent_Identity=30.6603773584906, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=256, Percent_Identity=28.515625, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=28.8, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=28.968253968254, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=27.734375, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI2367175, Length=204, Percent_Identity=32.3529411764706, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=52.7777777777778, Blast_Score=235, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=29.9212598425197, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=30.5220883534137, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=29.9610894941634, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=267, Percent_Identity=28.0898876404494, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=203, Percent_Identity=33.0049261083744, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6320089, Length=222, Percent_Identity=26.1261261261261, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=55.3359683794466, Blast_Score=266, Evalue=8e-72,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=31.7460317460317, Blast_Score=100, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25788; Mature: 25788

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVVVDLRGDDVVGGLGDRARFAQADVTDE
CCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCEECCCCCCHHHHHCCCCHH
AAVSNALELADSLGPVRVVVNCAGTGNAIRVLSRDGVFPLAAFRKIVDINLVGTFNVLRL
HHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHEEEEECHHHHHHH
GAERIAKTEPIGEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIARDLASKLIR
HHHHHHCCCCCCCCCCEEEEECEEEEECCCCCHHHHCCCCCCEEEEEHHHHHHHHHHHHH
VVTIAPGLFDTPLLASLPAEAKASLGQQVPHPSRLGNPDEYGALVLHIIENPMLNGEVIR
HHHCCCCCCCCCHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHEEEEECCCCCCCCEEEE
LDGAIRMAPR
ECCEEEECCC
>Mature Secondary Structure
MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVVVDLRGDDVVGGLGDRARFAQADVTDE
CCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCEECCCCCCHHHHHCCCCHH
AAVSNALELADSLGPVRVVVNCAGTGNAIRVLSRDGVFPLAAFRKIVDINLVGTFNVLRL
HHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHEEEEECHHHHHHH
GAERIAKTEPIGEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIARDLASKLIR
HHHHHHCCCCCCCCCCEEEEECEEEEECCCCCHHHHCCCCCCEEEEEHHHHHHHHHHHHH
VVTIAPGLFDTPLLASLPAEAKASLGQQVPHPSRLGNPDEYGALVLHIIENPMLNGEVIR
HHHCCCCCCCCCHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHEEEEECCCCCCCCEEEE
LDGAIRMAPR
ECCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]