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The map label for this gene is gltA1 [H]

Identifier: 121637063

GI number: 121637063

Start: 1287547

End: 1288728

Strand: Direct

Name: gltA1 [H]

Synonym: BCG_1192

Alternate gene names: 121637063

Gene position: 1287547-1288728 (Clockwise)

Preceding gene: 121637062

Following gene: 121637064

Centisome position: 29.43

GC content: 66.16

Gene sequence:

>1182_bases
ATGACCGGGCCGCTCGCGGCGGCCAGGTCCGTCGCTGCCACGAAATCGATGACCGCGCCCACCGTTGATGAGCGGCCCGA
CATCAAAAAGGGCCTCGCCGGCGTGGTGGTGGACACCACCGCCATCTCCAAGGTGGTGCCGCAGACCAATTCGTTGACCT
ACCGGGGATATCCGGTCCAGGATCTGGCAGCCCGCTGCAGTTTCGAGCAGGTCGCCTTCCTGCTGTGGCGTGGTGAGTTG
CCCACCGATGCCGAGCTGGCGTTGTTCAGCCAGCGCGAACGAGCCAGCCGTCGGGTGGACCGCTCGATGCTGTCATTGCT
GGCCAAGCTGCCGGACAACTGCCACCCGATGGACGTGGTGCGCACCGCGATCAGCTATCTCGGTGCCGAGGACCCGGACG
AGGACGACGCCGCGGCCAACCGGGCCAAGGCGATGCGCATGATGGCGGTGTTGCCGACGATCGTGGCGATCGACATGCGG
CGCCGACGCGGGTTGCCCCCGATCGCACCGCACAGCGGGCTCGGTTATGCGCAGAACTTCCTGCACATGTGCTTCGGGGA
GGTACCCGAAACCGCCGTCGTGTCGGCGTTCGAGCAGTCGATGATCCTCTACGCCGAGCACGGATTCAACGCGTCGACGT
TCGCCGCCCGGGTGGTGACCTCGACCCAATCCGACATCTACAGCGCGGTGACCGGCGCGATCGGCGCCCTCAAGGGGCGG
CTACACGGCGGCGCCAACGAAGCCGTCATGCACGACATGATCGAGATCGGCGATCCGGCCAACGCGCGGGAGTGGTTGCG
CGCCAAGCTCGCCCGCAAGGAAAAGATCATGGGCTTCGGGCATCGGGTGTACCGGCACGGCGACTCCCGGGTGCCGACCA
TGAAACGGGCGCTGGAGCGCGTGGGGACCGTTCGCGACGGCCAGCGATGGCTGGACATCTACCAGGTGTTAGCGGCCGAG
ATGGCGTCGGCCACCGGGATCTTGCCCAACCTCGATTTTCCGACCGGGCCCGCGTACTACCTGATGGGATTCGACATCGC
CAGCTTCACCCCGATCTTCGTGATGAGTAGGATCACCGGCTGGACCGCACACATCATGGAACAGGCCACGGCCAACGCGC
TGATCCGGCCGCTGAGCGCATATTGCGGGCACGAGCAGCGGGTGTTACCGGGCACCTTCTAG

Upstream 100 bases:

>100_bases
GTCTCGCCGATCTCGAGAGCGGTGCCGTGGGTGGGCTGAACGTGTTGGTCGATCCGCGGGTGCTGGACAAAGCGCCGGTG
ATTCCACCAGGAATCTTTCG

Downstream 100 bases:

>100_bases
TCTTATGGGCCATGGGATTTCTCCAGCCCCGACTTCCCGACATCGACCTGGCCGAATGGAGCCAGGGCTCCCGCAGCCAG
AAGATCCGGCCGATGGCCCA

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTGPLAAARSVAATKSMTAPTVDERPDIKKGLAGVVVDTTAISKVVPQTNSLTYRGYPVQDLAARCSFEQVAFLLWRGEL
PTDAELALFSQRERASRRVDRSMLSLLAKLPDNCHPMDVVRTAISYLGAEDPDEDDAAANRAKAMRMMAVLPTIVAIDMR
RRRGLPPIAPHSGLGYAQNFLHMCFGEVPETAVVSAFEQSMILYAEHGFNASTFAARVVTSTQSDIYSAVTGAIGALKGR
LHGGANEAVMHDMIEIGDPANAREWLRAKLARKEKIMGFGHRVYRHGDSRVPTMKRALERVGTVRDGQRWLDIYQVLAAE
MASATGILPNLDFPTGPAYYLMGFDIASFTPIFVMSRITGWTAHIMEQATANALIRPLSAYCGHEQRVLPGTF

Sequences:

>Translated_393_residues
MTGPLAAARSVAATKSMTAPTVDERPDIKKGLAGVVVDTTAISKVVPQTNSLTYRGYPVQDLAARCSFEQVAFLLWRGEL
PTDAELALFSQRERASRRVDRSMLSLLAKLPDNCHPMDVVRTAISYLGAEDPDEDDAAANRAKAMRMMAVLPTIVAIDMR
RRRGLPPIAPHSGLGYAQNFLHMCFGEVPETAVVSAFEQSMILYAEHGFNASTFAARVVTSTQSDIYSAVTGAIGALKGR
LHGGANEAVMHDMIEIGDPANAREWLRAKLARKEKIMGFGHRVYRHGDSRVPTMKRALERVGTVRDGQRWLDIYQVLAAE
MASATGILPNLDFPTGPAYYLMGFDIASFTPIFVMSRITGWTAHIMEQATANALIRPLSAYCGHEQRVLPGTF
>Mature_392_residues
TGPLAAARSVAATKSMTAPTVDERPDIKKGLAGVVVDTTAISKVVPQTNSLTYRGYPVQDLAARCSFEQVAFLLWRGELP
TDAELALFSQRERASRRVDRSMLSLLAKLPDNCHPMDVVRTAISYLGAEDPDEDDAAANRAKAMRMMAVLPTIVAIDMRR
RRGLPPIAPHSGLGYAQNFLHMCFGEVPETAVVSAFEQSMILYAEHGFNASTFAARVVTSTQSDIYSAVTGAIGALKGRL
HGGANEAVMHDMIEIGDPANAREWLRAKLARKEKIMGFGHRVYRHGDSRVPTMKRALERVGTVRDGQRWLDIYQVLAAEM
ASATGILPNLDFPTGPAYYLMGFDIASFTPIFVMSRITGWTAHIMEQATANALIRPLSAYCGHEQRVLPGTF

Specific function: Catalyzes The Synthesis Of 2-Methylcitrate From Propionyl-CoA And Oxaloacetate. Also Catalyzes The Condensation Of Oxaloacetate With Acetyl-CoA But With A Lower Specificity. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=396, Percent_Identity=25, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1786527, Length=366, Percent_Identity=38.2513661202186, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1786939, Length=353, Percent_Identity=30.3116147308782, Blast_Score=152, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17555174, Length=371, Percent_Identity=25.6064690026954, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6319850, Length=338, Percent_Identity=23.6686390532544, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640124, Length=409, Percent_Identity=24.9388753056235, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24640126, Length=409, Percent_Identity=24.9388753056235, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 42970; Mature: 42839

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGPLAAARSVAATKSMTAPTVDERPDIKKGLAGVVVDTTAISKVVPQTNSLTYRGYPVQ
CCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHEEHHHHHHHHCCCCCCEEECCCCHH
DLAARCSFEQVAFLLWRGELPTDAELALFSQRERASRRVDRSMLSLLAKLPDNCHPMDVV
HHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
RTAISYLGAEDPDEDDAAANRAKAMRMMAVLPTIVAIDMRRRRGLPPIAPHSGLGYAQNF
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
LHMCFGEVPETAVVSAFEQSMILYAEHGFNASTFAARVVTSTQSDIYSAVTGAIGALKGR
HHHHHCCCCHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHGGANEAVMHDMIEIGDPANAREWLRAKLARKEKIMGFGHRVYRHGDSRVPTMKRALER
HCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VGTVRDGQRWLDIYQVLAAEMASATGILPNLDFPTGPAYYLMGFDIASFTPIFVMSRITG
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
WTAHIMEQATANALIRPLSAYCGHEQRVLPGTF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TGPLAAARSVAATKSMTAPTVDERPDIKKGLAGVVVDTTAISKVVPQTNSLTYRGYPVQ
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHEEHHHHHHHHCCCCCCEEECCCCHH
DLAARCSFEQVAFLLWRGELPTDAELALFSQRERASRRVDRSMLSLLAKLPDNCHPMDVV
HHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
RTAISYLGAEDPDEDDAAANRAKAMRMMAVLPTIVAIDMRRRRGLPPIAPHSGLGYAQNF
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
LHMCFGEVPETAVVSAFEQSMILYAEHGFNASTFAARVVTSTQSDIYSAVTGAIGALKGR
HHHHHCCCCHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHGGANEAVMHDMIEIGDPANAREWLRAKLARKEKIMGFGHRVYRHGDSRVPTMKRALER
HCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VGTVRDGQRWLDIYQVLAAEMASATGILPNLDFPTGPAYYLMGFDIASFTPIFVMSRITG
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
WTAHIMEQATANALIRPLSAYCGHEQRVLPGTF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1883331 [H]