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The map label for this gene is PE_PGRS18 [H]

Identifier: 121636907

GI number: 121636907

Start: 1125567

End: 1126940

Strand: Reverse

Name: PE_PGRS18 [H]

Synonym: BCG_1035c

Alternate gene names: 121636907

Gene position: 1126940-1125567 (Counterclockwise)

Preceding gene: 121636912

Following gene: 121636905

Centisome position: 25.76

GC content: 71.25

Gene sequence:

>1374_bases
ATGTCGTTTGTCAACGTGGCCCCACAGTTAGTGTCCACAGCCGCGGCCGATGCGGCGCGGATCGGCTCGGCGATCAACAC
CGCCAACACCGCGGCGGCGGCGACCACCCAGGTGTTGGCCGCCGCCCAAGACGAGGTGTCAACGGCGATCGCGGCGCTGT
TCGGCAGCCACGGCCAGCACTATCAAGCGATCAGCGCGCAGGTCGCGGCCTACCAGGAACGGTTCGTGCTGGCCTTAAGC
CAAGCTAGCAGCACCTACGCGGTCGCCGAAGCGGCCAGCGCAACACCGCTGCAGAACGTGCTCGATGCGATCAACGCACC
CGTTCAGTCGCTGACCGGGCGCCCATTGATCGGCGACGGCGCGAACGGGATCGACGGGACCGGGCAAGCCGGCGGTAACG
GCGGGTGGCTGTGGGGCAACGGCGGCAACGGCGGGTCGGGGGCACCCGGGCAGGCCGGCGGGGCCGGCGGTGCGGCCGGG
TTGATCGGCAACGGTGGGGCCGGCGGAGCTGGCGGCCAGGGCCTACCCTTTGAGGCCGGCGCGAACGGCGGAGCCGGCGG
CGCCGGTGGATGGCTGTTCGGCAACGGCGGGGCCGGTGGTGTCGGCGGGGCCGGCGGAGCCGGCACAACCTTCGGTGTGG
CCGGCGGTGACGGTGGCACCGGCGGGGTTGGTGGTCACGGCGGGTTAATCGGTGTGGGTGGACACGGCGGGGACGGCGGG
ACCGGCGGCACCGGCGGCGCGGTCAGCCTCGCCCGCGCCGGCACCGCCGGCGGCGCCGGCGGCGGCCCGGCCGGCGGTAT
CGGCGGTGCGGGTGGGGTCGGCGGTGCCGGTGGGGCCGCCGGCGCCGTCACCACCATCACCCACGCCAGCTTCAACGATC
CGCACGGGGTGGCGGTCAACCCGGGCGGCAACATCTACGTCACCAACCAGGGCAGCAACACGGTGTCGGTGATCGACCCG
GTCACCAACACCGTCACCGGCTCCATCACCGACGGCAACGGTCCAAGCGGGGTGGCGGTCAGCCCCGTCACCGGCCTGGT
CTTCGTGACCAACTTCGACAGCAACACGGTGTCGGTGATCGACCCGAACACCAACACCGTCACCGGCTCCATCCCCGTCG
GTACCGGTGCGTATGGGGTGGCGGTCAACCCAGGCGGCAACATCTACGTCACCAACCAGTTCAGCAACACGGTGTCGGTG
ATCGACCCGGCCACCAACACCGTCACCGGCTCCCCCATCCCCGTCGGACTCGACCCGACAGGGGTGGCGGTCAACCCCGT
CACCGGCGTGGTCTACGTCACTAACTCTCTCGACGACACGGTGTCGGTGATCACCGGAGAGCCGGCGCGCTCGGTGTGTT
CGGCGGCCATATGA

Upstream 100 bases:

>100_bases
TGGAACGGCAGGGATCGTCCGAATAAACGGTTACCCACCGCAGGGGTAACAGGCGGTGGGCCGCCCGCATCTCAACATCG
TCGCGGTCAGGAGGATTTCG

Downstream 100 bases:

>100_bases
TCGTCGGCCGCCGGCGCGTCAGCGCTTATCGAAATCGATGAGGCCGAGCCGGGCGGCCTTGAGCAAGCGCCGAGGCACCT
TGTGGGCGTGACCGGCGACG

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQERFVLALS
QASSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAG
LIGNGGAGGAGGQGLPFEAGANGGAGGAGGWLFGNGGAGGVGGAGGAGTTFGVAGGDGGTGGVGGHGGLIGVGGHGGDGG
TGGTGGAVSLARAGTAGGAGGGPAGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNIYVTNQGSNTVSVIDP
VTNTVTGSITDGNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSV
IDPATNTVTGSPIPVGLDPTGVAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI

Sequences:

>Translated_457_residues
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQERFVLALS
QASSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAG
LIGNGGAGGAGGQGLPFEAGANGGAGGAGGWLFGNGGAGGVGGAGGAGTTFGVAGGDGGTGGVGGHGGLIGVGGHGGDGG
TGGTGGAVSLARAGTAGGAGGGPAGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNIYVTNQGSNTVSVIDP
VTNTVTGSITDGNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSV
IDPATNTVTGSPIPVGLDPTGVAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI
>Mature_456_residues
SFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQERFVLALSQ
ASSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAGL
IGNGGAGGAGGQGLPFEAGANGGAGGAGGWLFGNGGAGGVGGAGGAGTTFGVAGGDGGTGGVGGHGGLIGVGGHGGDGGT
GGTGGAVSLARAGTAGGAGGGPAGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNIYVTNQGSNTVSVIDPV
TNTVTGSITDGNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSVI
DPATNTVTGSPIPVGLDPTGVAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI

Specific function: Unknown

COG id: COG3391

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 42066; Mature: 41935

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: PS51125 NHL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQH
CCHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
YQAISAQVAAYQERFVLALSQASSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDG
HHHHHHHHHHHHHHEEEEEECCCCEEEEHHCCCCCHHHHHHHHHCCCHHHHCCCCEECCC
ANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAGLIGNGGAGGAGGQGLPFEAG
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCC
ANGGAGGAGGWLFGNGGAGGVGGAGGAGTTFGVAGGDGGTGGVGGHGGLIGVGGHGGDGG
CCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCC
TGGTGGAVSLARAGTAGGAGGGPAGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVN
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEC
PGGNIYVTNQGSNTVSVIDPVTNTVTGSITDGNGPSGVAVSPVTGLVFVTNFDSNTVSVI
CCCCEEEECCCCCEEEEECCCCCCEEEEEECCCCCCCEEECCCEEEEEEEECCCCEEEEE
DPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSVIDPATNTVTGSPIPVGLDPT
CCCCCEEEEECCCCCCCEEEEECCCCCEEEEECCCCEEEEECCCCCCCCCCCEEECCCCC
GVAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI
CEEECCCEEEEEEECCCCCEEEEEECCCHHHHHHHCC
>Mature Secondary Structure 
SFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQH
CHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
YQAISAQVAAYQERFVLALSQASSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDG
HHHHHHHHHHHHHHEEEEEECCCCEEEEHHCCCCCHHHHHHHHHCCCHHHHCCCCEECCC
ANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAGLIGNGGAGGAGGQGLPFEAG
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCC
ANGGAGGAGGWLFGNGGAGGVGGAGGAGTTFGVAGGDGGTGGVGGHGGLIGVGGHGGDGG
CCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCC
TGGTGGAVSLARAGTAGGAGGGPAGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVN
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEC
PGGNIYVTNQGSNTVSVIDPVTNTVTGSITDGNGPSGVAVSPVTGLVFVTNFDSNTVSVI
CCCCEEEECCCCCEEEEECCCCCCEEEEEECCCCCCCEEECCCEEEEEEEECCCCEEEEE
DPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSVIDPATNTVTGSPIPVGLDPT
CCCCCEEEEECCCCCCCEEEEECCCCCEEEEECCCCEEEEECCCCCCCCCCCEEECCCCC
GVAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI
CEEECCCEEEEEEECCCCCEEEEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]