Click here to switch to the map view.

The map label for this gene is fadE13 [H]

Identifier: 121636901

GI number: 121636901

Start: 1117824

End: 1118972

Strand: Reverse

Name: fadE13 [H]

Synonym: BCG_1029c

Alternate gene names: 121636901

Gene position: 1118972-1117824 (Counterclockwise)

Preceding gene: 121636902

Following gene: 121636900

Centisome position: 25.58

GC content: 67.8

Gene sequence:

>1149_bases
GTGAACATCTGGACCACACCGGAGCGCCAACAGCTGCGAAAAACGGTGCGCGCCTTTGCCGAGCGCGAGATCCTGCCGCA
CGTCGACGAGTGGGAAAGGATCGGCGAGTTGCCCCGCGGCCTGCACCGGCTCGCCGGGGCCGCCGGGCTGCTGGGCGCCG
GCTTTCCCGAGGCGGTCGGTGGTGGCGGCGGTGACGGCGCCGACCCCGTCATCATCTGCGAGGAGATGCACCAGGCCGGC
GCCCCGGGCGGGGTGTATGCGTCCCTGTTCACCTGCGGTATCGCCGTACCGCACATGGTCGCATCCGGCGACGAACGGCT
GATCGCCACGTACGTGCGGCCCACCTTGGCCGGGGAGAAGATCGGCGCGCTGGCCATCACCGAACCCGGCGGCGGCTCCG
ACGTCGGGCATCTACGGACCAGCGCGGTACGGGACGGCGACCATTACGTGATCAACGGCGCCAAGACCTACATCACCTCC
GGCGTGCGGGCCGACTACGTGGTCACCGCGGTGCGAACCGGTGGACCCGGTGCCGCCGGGGTTTCGCTGCTGGTGGTGGA
AAAGGACACCCCCGGCTTTGAGGTGACCCGCAAGCTGGACAAGATGGGCTGGCGTTCCTCGGATACCGCCGAGCTGTGCT
ACACCGACGTGGCCGTGCCGGCGACTAACCTCGTGGGCGCCGAGAACAGCGGCTTCACCCAGATCGCCCGGGCATTTGTT
TCCGAGCGCATCGGCCTTGCCGCCCAGGCGTATTCGAGCGCCCAGCGGTGCCTGGACCTCACCGCGCAGTGGTGCCGGGA
CCGCGAGACGTTCGGTCGGCCGCTGATTTCACGCCAGTCGGTGCAGAACACGCTGGCCGAGATGGCCCGCCGCATCGACG
TCGCCCGGGTCTATGCGCACCATGTGGTGGAACGCCAGCTCGCCGGCGAGACCGACCTGATCGCGCAGGTGTGTTTCGCC
AAGAACACCGCCGTGCAGGCCGGGGAGTGGGTTGCCAACCAGGCCGTACAGCTGTTCGGCGGCATGGGTTACATGGCCGA
ATCCGAAGTCGAACGCCAATACCGGGACATGCGAATCCTCGGTATCGGAGGCGGCACCACCGAAATACTGACCGCTTTGG
CCGCCAAAACCCTGGGGTATCAATCGTGA

Upstream 100 bases:

>100_bases
TCGGCCAGGGCGTCGCCTACCAGGCCCGCTTCGACCCGCAGGCCAAGGGACTGGGTGAGTGGCTGCGCAGCCGCCACGTC
GAGATCCCGGAGACCCTGTT

Downstream 100 bases:

>100_bases
CCGTGCTGCAATCCACACTGGACCCGAACGCTTCCGCCTACGACGAGGCGGCCGCGACGATGAGCGGCAAGCTCGACGAG
ATCAACGCCGAACTGGCCAA

Product: putative acyl-coa dehydrogenase fadE13

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MNIWTTPERQQLRKTVRAFAEREILPHVDEWERIGELPRGLHRLAGAAGLLGAGFPEAVGGGGGDGADPVIICEEMHQAG
APGGVYASLFTCGIAVPHMVASGDERLIATYVRPTLAGEKIGALAITEPGGGSDVGHLRTSAVRDGDHYVINGAKTYITS
GVRADYVVTAVRTGGPGAAGVSLLVVEKDTPGFEVTRKLDKMGWRSSDTAELCYTDVAVPATNLVGAENSGFTQIARAFV
SERIGLAAQAYSSAQRCLDLTAQWCRDRETFGRPLISRQSVQNTLAEMARRIDVARVYAHHVVERQLAGETDLIAQVCFA
KNTAVQAGEWVANQAVQLFGGMGYMAESEVERQYRDMRILGIGGGTTEILTALAAKTLGYQS

Sequences:

>Translated_382_residues
MNIWTTPERQQLRKTVRAFAEREILPHVDEWERIGELPRGLHRLAGAAGLLGAGFPEAVGGGGGDGADPVIICEEMHQAG
APGGVYASLFTCGIAVPHMVASGDERLIATYVRPTLAGEKIGALAITEPGGGSDVGHLRTSAVRDGDHYVINGAKTYITS
GVRADYVVTAVRTGGPGAAGVSLLVVEKDTPGFEVTRKLDKMGWRSSDTAELCYTDVAVPATNLVGAENSGFTQIARAFV
SERIGLAAQAYSSAQRCLDLTAQWCRDRETFGRPLISRQSVQNTLAEMARRIDVARVYAHHVVERQLAGETDLIAQVCFA
KNTAVQAGEWVANQAVQLFGGMGYMAESEVERQYRDMRILGIGGGTTEILTALAAKTLGYQS
>Mature_382_residues
MNIWTTPERQQLRKTVRAFAEREILPHVDEWERIGELPRGLHRLAGAAGLLGAGFPEAVGGGGGDGADPVIICEEMHQAG
APGGVYASLFTCGIAVPHMVASGDERLIATYVRPTLAGEKIGALAITEPGGGSDVGHLRTSAVRDGDHYVINGAKTYITS
GVRADYVVTAVRTGGPGAAGVSLLVVEKDTPGFEVTRKLDKMGWRSSDTAELCYTDVAVPATNLVGAENSGFTQIARAFV
SERIGLAAQAYSSAQRCLDLTAQWCRDRETFGRPLISRQSVQNTLAEMARRIDVARVYAHHVVERQLAGETDLIAQVCFA
KNTAVQAGEWVANQAVQLFGGMGYMAESEVERQYRDMRILGIGGGTTEILTALAAKTLGYQS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=36.7724867724868, Blast_Score=245, Evalue=6e-65,
Organism=Homo sapiens, GI7656849, Length=372, Percent_Identity=33.6021505376344, Blast_Score=211, Evalue=9e-55,
Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=32.9758713136729, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI4557233, Length=365, Percent_Identity=34.7945205479452, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=32.5333333333333, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=32.5333333333333, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI226958414, Length=346, Percent_Identity=32.9479768786127, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=29.4117647058824, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI21361497, Length=351, Percent_Identity=27.3504273504274, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI4557235, Length=273, Percent_Identity=31.8681318681319, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI76496475, Length=273, Percent_Identity=31.8681318681319, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI4503943, Length=369, Percent_Identity=26.5582655826558, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI38505218, Length=409, Percent_Identity=25.6723716381418, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI211971008, Length=402, Percent_Identity=25.6218905472637, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI48976061, Length=402, Percent_Identity=25.6218905472637, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI7669494, Length=357, Percent_Identity=26.6106442577031, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI87081958, Length=353, Percent_Identity=31.4447592067989, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1786223, Length=347, Percent_Identity=27.0893371757925, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082384, Length=279, Percent_Identity=26.5232974910394, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=386, Percent_Identity=33.9378238341969, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17505929, Length=368, Percent_Identity=31.7934782608696, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17534899, Length=385, Percent_Identity=31.4285714285714, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17569725, Length=377, Percent_Identity=31.5649867374005, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17533517, Length=362, Percent_Identity=31.2154696132597, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17551932, Length=369, Percent_Identity=30.0813008130081, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17538396, Length=382, Percent_Identity=29.8429319371728, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17508101, Length=372, Percent_Identity=30.1075268817204, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17506239, Length=369, Percent_Identity=29.5392953929539, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI71990804, Length=258, Percent_Identity=32.5581395348837, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71985184, Length=277, Percent_Identity=31.4079422382672, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71982178, Length=268, Percent_Identity=29.1044776119403, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32563615, Length=236, Percent_Identity=30.9322033898305, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=366, Percent_Identity=25.9562841530055, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71985192, Length=207, Percent_Identity=31.4009661835749, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562446, Length=374, Percent_Identity=24.5989304812834, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356377, Length=363, Percent_Identity=33.3333333333333, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI21355753, Length=380, Percent_Identity=32.6315789473684, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24660351, Length=381, Percent_Identity=32.2834645669291, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24666513, Length=377, Percent_Identity=29.973474801061, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24646207, Length=363, Percent_Identity=32.2314049586777, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI281363737, Length=273, Percent_Identity=32.2344322344322, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI19920834, Length=372, Percent_Identity=26.0752688172043, Blast_Score=98, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 40748; Mature: 40748

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIWTTPERQQLRKTVRAFAEREILPHVDEWERIGELPRGLHRLAGAAGLLGAGFPEAVG
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCC
GGGGDGADPVIICEEMHQAGAPGGVYASLFTCGIAVPHMVASGDERLIATYVRPTLAGEK
CCCCCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCC
IGALAITEPGGGSDVGHLRTSAVRDGDHYVINGAKTYITSGVRADYVVTAVRTGGPGAAG
CCEEEEECCCCCCCHHHHHHHHCCCCCEEEECCHHHHHHCCCCCCEEEEEEECCCCCCCC
VSLLVVEKDTPGFEVTRKLDKMGWRSSDTAELCYTDVAVPATNLVGAENSGFTQIARAFV
EEEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHH
SERIGLAAQAYSSAQRCLDLTAQWCRDRETFGRPLISRQSVQNTLAEMARRIDVARVYAH
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HVVERQLAGETDLIAQVCFAKNTAVQAGEWVANQAVQLFGGMGYMAESEVERQYRDMRIL
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCEEEE
GIGGGTTEILTALAAKTLGYQS
EECCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNIWTTPERQQLRKTVRAFAEREILPHVDEWERIGELPRGLHRLAGAAGLLGAGFPEAVG
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCC
GGGGDGADPVIICEEMHQAGAPGGVYASLFTCGIAVPHMVASGDERLIATYVRPTLAGEK
CCCCCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCC
IGALAITEPGGGSDVGHLRTSAVRDGDHYVINGAKTYITSGVRADYVVTAVRTGGPGAAG
CCEEEEECCCCCCCHHHHHHHHCCCCCEEEECCHHHHHHCCCCCCEEEEEEECCCCCCCC
VSLLVVEKDTPGFEVTRKLDKMGWRSSDTAELCYTDVAVPATNLVGAENSGFTQIARAFV
EEEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHH
SERIGLAAQAYSSAQRCLDLTAQWCRDRETFGRPLISRQSVQNTLAEMARRIDVARVYAH
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HVVERQLAGETDLIAQVCFAKNTAVQAGEWVANQAVQLFGGMGYMAESEVERQYRDMRIL
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCEEEE
GIGGGTTEILTALAAKTLGYQS
EECCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]