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The map label for this gene is pgi [H]

Identifier: 121636871

GI number: 121636871

Start: 1085501

End: 1087162

Strand: Reverse

Name: pgi [H]

Synonym: BCG_1000c

Alternate gene names: 121636871

Gene position: 1087162-1085501 (Counterclockwise)

Preceding gene: 121636872

Following gene: 121636868

Centisome position: 24.85

GC content: 64.32

Gene sequence:

>1662_bases
ATGACCTCCGCGCCAATCCCCGACATCACCGCTACCCCGGCATGGGACGCCCTGCGCAGACATCACGATCAGATCGGAAA
CACCCATCTTCGCCAGTTCTTCGCCGACGATCCGGGTCGCGGCCGGGAGCTCACCGTCAGCGTCGGCGATCTCTACATCG
ACTACAGCAAACACCGCGTCACCCGCGAGACGCTGGCGCTGCTGATCGATCTGGCCCGGACGGCCCACCTCGAAGAGCGT
CGCGACCAGATGTTCGCCGGTGTGCATATCAACACCTCTGAGGATCGAGCGGTGTTGCACACCGCGCTGCGGCTGCCCCG
AGACGCCGAACTCGTCGTCGACGGCCAAGACGTCGTCACCGACGTACATGCCGTGCTCGACGCGATGGGCGCCTTCACCG
ACCGCCTGCGCAGCGGCGAGTGGACCGGAGCAACTGGAAAGCGGATCAGCACCGTCGTCAACATCGGCATCGGTGGTTCG
GATTTGGGTCCGGTGATGGTGTACCAAGCGTTGCGCCACTATGCCGACGCGGGCATTTCCGCGCGCTTCGTGTCCAACGT
CGATCCCGCCGACCTGATCGCCACGCTCGCCGATCTAGACCCCGCCACAACGCTTTTCATCGTCGCGTCGAAGACGTTCT
CGACGCTGGAGACATTGACCAATGCGACCGCGGCGCGTCGCTGGCTGACCGATGCGCTGGGCGACGCCGCGGTGTCGCGG
CATTTTGTCGCGGTGTCCACCAACAAGCGCCTGGTCGACGACTTCGGCATCAACACCGACAACATGTTCGGTTTTTGGGA
TTGGGTCGGCGGGCGTTATTCGGTGGATTCGGCGATCGGGCTGTCGTTGATGACGGTGATCGGCCGCGACGCCTTCGCCG
ATTTCTTGGCCGGATTCCACATCATCGACCGCCATTTCGCGACCGCTCCGCTGGAATCCAACGCGCCGGTGCTGCTTGGC
CTGATCGGACTGTGGTACTCCAATTTCTTCGGTGCGCAATCACGCACCGTGCTGCCGTATTCCAATGACTTGTCGCGTTT
TCCGGCCTACCTTCAGCAGTTGACCATGGAATCCAACGGCAAGTCCACGCGCGCCGACGGCAGCCCGGTCAGCGCCGACA
CCGGTGAAATCTTTTGGGGTGAACCGGGAACCAACGGCCAGCACGCCTTCTACCAGTTGCTGCACCAGGGCACCCGGCTG
GTGCCAGCCGATTTCATCGGCTTTGCTCAACCCCTCGACGACCTGCCGACCGCCGAGGGCACCGGCAGCATGCATGATCT
GCTGATGAGCAACTTCTTCGCCCAAACCCAGGTGCTGGCGTTCGGCAAGACCGCCGAGGAGATCGCCGCCGACGGCACCC
CCGCCCACGTGGTAGCGCATAAGGTGATGCCCGGCAACCGGCCGTCCACCTCAATTCTGGCCAGTCGGCTCACGCCGTCG
GTGCTGGGGCAGTTGATCGCGCTCTACGAGCATCAGGTGTTCACCGAGGGTGTGGTGTGGGGTATCGACTCGTTCGACCA
GTGGGGGGTGGAGCTGGGCAAGACGCAGGCCAAGGCGCTGCTTCCGGTAATCACCGGCGCCGGTTCACCGCCACCGCAGT
CGGACAGCTCGACCGACGGGCTGGTGCGCCGCTACCGCACCGAACGTGGCCGCGCGGGCTAG

Upstream 100 bases:

>100_bases
ATACCGCGACAAACGGCGAGTGCCGCCGAGCACGATAACTAAAGGCTCGGCGAAGACAGCGGCTCTGATCGACGCCACTC
CACGGCATTAGGGTCGAACC

Downstream 100 bases:

>100_bases
GTGGCCGAGCGCCCGCTAGGCGAAGCGTCTGGTCAGCCGCGGCGGCAGCACCCACATCAGCCGCACCAGTGGCGCCCATG
GCCACCAGGGGACCGCGGCG

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MTSAPIPDITATPAWDALRRHHDQIGNTHLRQFFADDPGRGRELTVSVGDLYIDYSKHRVTRETLALLIDLARTAHLEER
RDQMFAGVHINTSEDRAVLHTALRLPRDAELVVDGQDVVTDVHAVLDAMGAFTDRLRSGEWTGATGKRISTVVNIGIGGS
DLGPVMVYQALRHYADAGISARFVSNVDPADLIATLADLDPATTLFIVASKTFSTLETLTNATAARRWLTDALGDAAVSR
HFVAVSTNKRLVDDFGINTDNMFGFWDWVGGRYSVDSAIGLSLMTVIGRDAFADFLAGFHIIDRHFATAPLESNAPVLLG
LIGLWYSNFFGAQSRTVLPYSNDLSRFPAYLQQLTMESNGKSTRADGSPVSADTGEIFWGEPGTNGQHAFYQLLHQGTRL
VPADFIGFAQPLDDLPTAEGTGSMHDLLMSNFFAQTQVLAFGKTAEEIAADGTPAHVVAHKVMPGNRPSTSILASRLTPS
VLGQLIALYEHQVFTEGVVWGIDSFDQWGVELGKTQAKALLPVITGAGSPPPQSDSSTDGLVRRYRTERGRAG

Sequences:

>Translated_553_residues
MTSAPIPDITATPAWDALRRHHDQIGNTHLRQFFADDPGRGRELTVSVGDLYIDYSKHRVTRETLALLIDLARTAHLEER
RDQMFAGVHINTSEDRAVLHTALRLPRDAELVVDGQDVVTDVHAVLDAMGAFTDRLRSGEWTGATGKRISTVVNIGIGGS
DLGPVMVYQALRHYADAGISARFVSNVDPADLIATLADLDPATTLFIVASKTFSTLETLTNATAARRWLTDALGDAAVSR
HFVAVSTNKRLVDDFGINTDNMFGFWDWVGGRYSVDSAIGLSLMTVIGRDAFADFLAGFHIIDRHFATAPLESNAPVLLG
LIGLWYSNFFGAQSRTVLPYSNDLSRFPAYLQQLTMESNGKSTRADGSPVSADTGEIFWGEPGTNGQHAFYQLLHQGTRL
VPADFIGFAQPLDDLPTAEGTGSMHDLLMSNFFAQTQVLAFGKTAEEIAADGTPAHVVAHKVMPGNRPSTSILASRLTPS
VLGQLIALYEHQVFTEGVVWGIDSFDQWGVELGKTQAKALLPVITGAGSPPPQSDSSTDGLVRRYRTERGRAG
>Mature_552_residues
TSAPIPDITATPAWDALRRHHDQIGNTHLRQFFADDPGRGRELTVSVGDLYIDYSKHRVTRETLALLIDLARTAHLEERR
DQMFAGVHINTSEDRAVLHTALRLPRDAELVVDGQDVVTDVHAVLDAMGAFTDRLRSGEWTGATGKRISTVVNIGIGGSD
LGPVMVYQALRHYADAGISARFVSNVDPADLIATLADLDPATTLFIVASKTFSTLETLTNATAARRWLTDALGDAAVSRH
FVAVSTNKRLVDDFGINTDNMFGFWDWVGGRYSVDSAIGLSLMTVIGRDAFADFLAGFHIIDRHFATAPLESNAPVLLGL
IGLWYSNFFGAQSRTVLPYSNDLSRFPAYLQQLTMESNGKSTRADGSPVSADTGEIFWGEPGTNGQHAFYQLLHQGTRLV
PADFIGFAQPLDDLPTAEGTGSMHDLLMSNFFAQTQVLAFGKTAEEIAADGTPAHVVAHKVMPGNRPSTSILASRLTPSV
LGQLIALYEHQVFTEGVVWGIDSFDQWGVELGKTQAKALLPVITGAGSPPPQSDSSTDGLVRRYRTERGRAG

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=555, Percent_Identity=47.2072072072072, Blast_Score=521, Evalue=1e-148,
Organism=Homo sapiens, GI296080693, Length=555, Percent_Identity=43.6036036036036, Blast_Score=465, Evalue=1e-131,
Organism=Escherichia coli, GI1790457, Length=554, Percent_Identity=51.2635379061372, Blast_Score=548, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI71996708, Length=539, Percent_Identity=48.60853432282, Blast_Score=498, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI71996703, Length=539, Percent_Identity=48.60853432282, Blast_Score=497, Evalue=1e-141,
Organism=Saccharomyces cerevisiae, GI6319673, Length=546, Percent_Identity=49.2673992673993, Blast_Score=526, Evalue=1e-150,
Organism=Drosophila melanogaster, GI24651916, Length=556, Percent_Identity=49.1007194244604, Blast_Score=530, Evalue=1e-150,
Organism=Drosophila melanogaster, GI24651914, Length=556, Percent_Identity=49.1007194244604, Blast_Score=530, Evalue=1e-150,
Organism=Drosophila melanogaster, GI17737445, Length=556, Percent_Identity=49.1007194244604, Blast_Score=530, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 59975; Mature: 59844

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAPIPDITATPAWDALRRHHDQIGNTHLRQFFADDPGRGRELTVSVGDLYIDYSKHRV
CCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCEEEEEECCEEEECHHHHH
TRETLALLIDLARTAHLEERRDQMFAGVHINTSEDRAVLHTALRLPRDAELVVDGQDVVT
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHCCCCCEEEECCHHHHH
DVHAVLDAMGAFTDRLRSGEWTGATGKRISTVVNIGIGGSDLGPVMVYQALRHYADAGIS
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCC
ARFVSNVDPADLIATLADLDPATTLFIVASKTFSTLETLTNATAARRWLTDALGDAAVSR
EEHHCCCCHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HFVAVSTNKRLVDDFGINTDNMFGFWDWVGGRYSVDSAIGLSLMTVIGRDAFADFLAGFH
EEEEEECCCEEHHHCCCCCCCCCEEHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHH
IIDRHFATAPLESNAPVLLGLIGLWYSNFFGAQSRTVLPYSNDLSRFPAYLQQLTMESNG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHCCCC
KSTRADGSPVSADTGEIFWGEPGTNGQHAFYQLLHQGTRLVPADFIGFAQPLDDLPTAEG
CCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCHHHCCCCCC
TGSMHDLLMSNFFAQTQVLAFGKTAEEIAADGTPAHVVAHKVMPGNRPSTSILASRLTPS
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHEECCCCCCCCHHHHHHHHCCHH
VLGQLIALYEHQVFTEGVVWGIDSFDQWGVELGKTQAKALLPVITGAGSPPPQSDSSTDG
HHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHH
LVRRYRTERGRAG
HHHHHHHHCCCCC
>Mature Secondary Structure 
TSAPIPDITATPAWDALRRHHDQIGNTHLRQFFADDPGRGRELTVSVGDLYIDYSKHRV
CCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCEEEEEECCEEEECHHHHH
TRETLALLIDLARTAHLEERRDQMFAGVHINTSEDRAVLHTALRLPRDAELVVDGQDVVT
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHCCCCCEEEECCHHHHH
DVHAVLDAMGAFTDRLRSGEWTGATGKRISTVVNIGIGGSDLGPVMVYQALRHYADAGIS
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCC
ARFVSNVDPADLIATLADLDPATTLFIVASKTFSTLETLTNATAARRWLTDALGDAAVSR
EEHHCCCCHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HFVAVSTNKRLVDDFGINTDNMFGFWDWVGGRYSVDSAIGLSLMTVIGRDAFADFLAGFH
EEEEEECCCEEHHHCCCCCCCCCEEHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHH
IIDRHFATAPLESNAPVLLGLIGLWYSNFFGAQSRTVLPYSNDLSRFPAYLQQLTMESNG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHCCCC
KSTRADGSPVSADTGEIFWGEPGTNGQHAFYQLLHQGTRLVPADFIGFAQPLDDLPTAEG
CCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCHHHCCCCCC
TGSMHDLLMSNFFAQTQVLAFGKTAEEIAADGTPAHVVAHKVMPGNRPSTSILASRLTPS
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHEECCCCCCCCHHHHHHHHCCHH
VLGQLIALYEHQVFTEGVVWGIDSFDQWGVELGKTQAKALLPVITGAGSPPPQSDSSTDG
HHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHH
LVRRYRTERGRAG
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA