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The map label for this gene is PPE14

Identifier: 121636838

GI number: 121636838

Start: 1050533

End: 1051804

Strand: Reverse

Name: PPE14

Synonym: BCG_0967c

Alternate gene names: 121636838

Gene position: 1051804-1050533 (Counterclockwise)

Preceding gene: 121636839

Following gene: 121636837

Centisome position: 24.04

GC content: 69.5

Gene sequence:

>1272_bases
ATGGATTTCGGGCTTTTACCTCCGGAAGTGAATTCAAGCCGAATGTATTCCGGTCCGGGGCCGGAGTCGATGCTAGCCGC
CGCGGCCGCCTGGGACGGTGTGGCCGCGGAGTTGACTTCCGCCGCGGTCTCGTATGGATCGGTGGTGTCGACGCTGATCG
TTGAGCCGTGGATGGGGCCGGCGGCGGCCGCGATGGCGGCCGCGGCAACGCCGTATGTGGGGTGGCTGGCCGCCACGGCG
GCGCTGGCGAAGGAGACGGCCACACAGGCGAGGGCAGCGGCGGAAGCGTTTGGGACGGCGTTCGCGATGACGGTGCCACC
ATCCCTCGTCGCGGCCAACCGCAGCCGGTTGATGTCGCTGGTCGCGGCGAACATTCTGGGGCAAAACAGTGCGGCGATCG
CGGCTACCCAGGCCGAGTATGCCGAAATGTGGGCCCAAGACGCTGCCGTGATGTACAGCTATGAGGGGGCATCTGCGGCC
GCGTCGGCGTTGCCGCCGTTCACTCCACCCGTGCAAGGCACCGGCCCGGCCGGGCCCGCGGCCGCAGCCGCGGCGACCCA
AGCCGCCGGTGCGGGCGCCGTTGCGGATGCACAGGCGACACTGGCCCAGCTGCCCCCGGGGATCCTGAGCGACATTCTGT
CCGCATTGGCCGCCAACGCTGATCCGCTGACATCGGGACTGTTGGGGATCGCGTCGACCCTCAACCCGCAAGTCGGATCC
GCTCAGCCGATAGTGATCCCCACCCCGATAGGGGAATTGGACGTGATCGCGCTCTACATTGCATCCATCGCGACCGGCAG
CATTGCGCTCGCGATCACGAACACGGCCAGACCCTGGCACATCGGCCTATACGGGAACGCCGGCGGGCTGGGACCGACGC
AGGGCCATCCACTGAGTTCGGCGACCGACGAGCCGGAGCCGCACTGGGGCCCCTTCGGGGGCGCGGCGCCGGTGTCCGCG
GGCGTCGGCCACGCAGCATTAGTCGGAGCGTTGTCGGTGCCGCACAGCTGGACCACGGCCGCCCCGGAGATCCAGCTCGC
CGTTCAGGCAACACCCACCTTCAGCTCCAGCGCCGGCGCCGACCCGACGGCCCTAAACGGGATGCCGGCAGGCCTGCTCA
GCGGGATGGCTTTGGCGAGCCTGGCCGCACGCGGCACGACGGGCGGTGGCGGCACCCGTAGCGGCACCAGCACTGACGGC
CAAGAGGACGGCCGCAAACCCCCGGTAGTTGTGATTAGAGAGCAGCCGCCGCCCGGAAACCCCCCGCGGTAA

Upstream 100 bases:

>100_bases
TCCATGGCATGTTCGTGGCCCTCCCGGCGGCCACCGCCGATGCGTATGCGACCACCGAGGCCGTCAATGTGGTCGCGACC
GGTTAAGGAGGTTGCTGGCA

Downstream 100 bases:

>100_bases
AAGTCCGGCAACCGTTCGTCGCCGCGCGGAAAATGCCTGGTGAGCGTGGCTATCCGACGGGCCGTTCACACCGCTTGTAG
TAGCGTACGGCTATGGACGA

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGPAAAAMAAAATPYVGWLAATA
ALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSLVAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAA
ASALPPFTPPVQGTGPAGPAAAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS
AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSA
GVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDG
QEDGRKPPVVVIREQPPPGNPPR

Sequences:

>Translated_423_residues
MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGPAAAAMAAAATPYVGWLAATA
ALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSLVAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAA
ASALPPFTPPVQGTGPAGPAAAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS
AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSA
GVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDG
QEDGRKPPVVVIREQPPPGNPPR
>Mature_423_residues
MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGPAAAAMAAAATPYVGWLAATA
ALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSLVAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAA
ASALPPFTPPVQGTGPAGPAAAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS
AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSA
GVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDG
QEDGRKPPVVVIREQPPPGNPPR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE14_MYCTU (Q79FV1)

Other databases:

- EMBL:   BX842574
- EMBL:   AE000516
- PIR:   C70582
- RefSeq:   NP_335373.1
- RefSeq:   YP_177765.1
- HSSP:   Q79FE1
- ProteinModelPortal:   Q79FV1
- SMR:   Q79FV1
- EnsemblBacteria:   EBMYCT00000003563
- EnsemblBacteria:   EBMYCT00000071043
- GeneID:   885069
- GeneID:   926255
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0940
- KEGG:   mtu:Rv0915c
- TIGR:   MT0940
- TubercuList:   Rv0915c
- GeneTree:   EBGT00050000014887
- HOGENOM:   HBG572308
- OMA:   PPRIAAN
- ProtClustDB:   CLSK799755
- InterPro:   IPR022171
- InterPro:   IPR000030

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE

EC number: NA

Molecular weight: Translated: 41440; Mature: 41440

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP
CCCCCCCCCCCCCCEECCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHH
VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA
HHHHHHCCCCCEEEEHHHHHHHHHHHCCEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCH
AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS
HHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS
CCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCC
ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCC
DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCC
PPR
CCC
>Mature Secondary Structure
MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP
CCCCCCCCCCCCCCEECCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHH
VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA
HHHHHHCCCCCEEEEHHHHHHHHHHHCCEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCH
AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS
HHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS
CCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCC
ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCC
DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCC
PPR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036