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The map label for this gene is ybdL [H]

Identifier: 121636781

GI number: 121636781

Start: 984232

End: 985425

Strand: Reverse

Name: ybdL [H]

Synonym: BCG_0910c

Alternate gene names: 121636781

Gene position: 985425-984232 (Counterclockwise)

Preceding gene: 121636784

Following gene: 121636776

Centisome position: 22.53

GC content: 67.92

Gene sequence:

>1194_bases
ATGACGGTGTCGCGGCTGCGGCCGTATGCGACCACGGTGTTCGCCGAAATGTCCGCGCTGGCCACCCGTATCGGCGCGGT
CAACCTGGGACAGGGCTTTCCCGACGAGGACGGCCCGCCGAAGATGCTGCAGGCCGCCCAAGACGCCATCGCCGGCGGCG
TCAACCAGTACCCGCCCGGCCCTGGAAGCGCTCCGCTACGGCGGGCCATCGCCGCCCAGCGGCGGCGCCATTTCGGCGTC
GACTACGACCCCGAGACCGAGGTGCTGGTCACGGTCGGAGCCACCGAGGCCATCGCCGCAGCGGTGCTCGGACTGGTCGA
ACCGGGCTCGGAGGTGTTGCTGATCGAGCCGTTCTACGACTCCTACTCGCCGGTGGTGGCGATGGCCGGCGCCCACCGCG
TGACCGTACCGCTGGTGCCCGATGGCCGCGGCTTCGCCCTAGACGCCGACGCGCTGCGACGCGCGGTGACCCCGCGAACT
CGGGCGCTGATCATTAACTCGCCGCACAATCCGACCGGTGCGGTGCTGAGCGCGACGGAACTCGCAGCCATCGCCGAGAT
CGCGGTGGCGGCGAACCTTGTGGTGATCACCGACGAGGTGTACGAGCACCTAGTGTTTGACCACGCCAGACACCTGCCGC
TGGCGGGTTTCGACGGCATGGCCGAGCGCACGATCACCATTTCCAGTGCGGCCAAGATGTTCAACTGCACCGGCTGGAAA
ATCGGATGGGCTTGCGGCCCAGCCGAACTCATCGCCGGGGTGCGCGCCGCAAAACAGTACCTGAGCTATGTGGGCGGCGC
ACCGTTTCAGCCTGCGGTCGCCCTCGCGCTAGACACCGAAGACGCCTGGGTGGCGGCCCTTCGGAACTCGTTGCGGGCCC
GGCGCGACCGGCTGGCAGCGGGCCTGACGGAGATCGGCTTCGCAGTGCACGACAGCTACGGCACGTACTTCCTATGCGCC
GACCCGCGCCCGTTGGGTTATGACGACAGCACCGAATTCTGTGCGGCGCTACCGGAGAAAGTCGGGGTGGCCGCCATCCC
GATGTCGGCGTTCTGCGACCCCGCCGCAGGACAGGCCTCACAACAAGCCGATGTGTGGAACCACCTGGTGCGCTTCACCT
TCTGCAAACGAGACGACACCCTCGACGAGGCAATCAGGCGACTGAGCGTGCTCGCCGAGCGACCCGCTACCTAG

Upstream 100 bases:

>100_bases
TAGGTCCCGTACCGGCACCCTAACAGGGCCCCCGGCCAACCTGTTGGTTGGGCAAGGTATCGCTGCGGCGCGCATCGTCG
CCCGGATAGGCTCGACCGCC

Downstream 100 bases:

>100_bases
CCCGACGTGAACCGTCGGCGCCCCACCACCTGCTTTCGCAGTCCTTCCGTCGCCGCATGGAGGATCTTCTTGCGGGCAAT
GTTGACCCAAAACGCCGGCA

Product: aminotransferase

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MTVSRLRPYATTVFAEMSALATRIGAVNLGQGFPDEDGPPKMLQAAQDAIAGGVNQYPPGPGSAPLRRAIAAQRRRHFGV
DYDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYDSYSPVVAMAGAHRVTVPLVPDGRGFALDADALRRAVTPRT
RALIINSPHNPTGAVLSATELAAIAEIAVAANLVVITDEVYEHLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWK
IGWACGPAELIAGVRAAKQYLSYVGGAPFQPAVALALDTEDAWVAALRNSLRARRDRLAAGLTEIGFAVHDSYGTYFLCA
DPRPLGYDDSTEFCAALPEKVGVAAIPMSAFCDPAAGQASQQADVWNHLVRFTFCKRDDTLDEAIRRLSVLAERPAT

Sequences:

>Translated_397_residues
MTVSRLRPYATTVFAEMSALATRIGAVNLGQGFPDEDGPPKMLQAAQDAIAGGVNQYPPGPGSAPLRRAIAAQRRRHFGV
DYDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYDSYSPVVAMAGAHRVTVPLVPDGRGFALDADALRRAVTPRT
RALIINSPHNPTGAVLSATELAAIAEIAVAANLVVITDEVYEHLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWK
IGWACGPAELIAGVRAAKQYLSYVGGAPFQPAVALALDTEDAWVAALRNSLRARRDRLAAGLTEIGFAVHDSYGTYFLCA
DPRPLGYDDSTEFCAALPEKVGVAAIPMSAFCDPAAGQASQQADVWNHLVRFTFCKRDDTLDEAIRRLSVLAERPAT
>Mature_396_residues
TVSRLRPYATTVFAEMSALATRIGAVNLGQGFPDEDGPPKMLQAAQDAIAGGVNQYPPGPGSAPLRRAIAAQRRRHFGVD
YDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYDSYSPVVAMAGAHRVTVPLVPDGRGFALDADALRRAVTPRTR
ALIINSPHNPTGAVLSATELAAIAEIAVAANLVVITDEVYEHLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWKI
GWACGPAELIAGVRAAKQYLSYVGGAPFQPAVALALDTEDAWVAALRNSLRARRDRLAAGLTEIGFAVHDSYGTYFLCAD
PRPLGYDDSTEFCAALPEKVGVAAIPMSAFCDPAAGQASQQADVWNHLVRFTFCKRDDTLDEAIRRLSVLAERPAT

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=416, Percent_Identity=35.8173076923077, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI56713254, Length=416, Percent_Identity=35.8173076923077, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI95147551, Length=409, Percent_Identity=33.4963325183374, Blast_Score=215, Evalue=5e-56,
Organism=Homo sapiens, GI169881279, Length=409, Percent_Identity=33.4963325183374, Blast_Score=215, Evalue=5e-56,
Organism=Homo sapiens, GI169881281, Length=375, Percent_Identity=30.6666666666667, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI4507369, Length=210, Percent_Identity=27.6190476190476, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1786816, Length=389, Percent_Identity=38.0462724935733, Blast_Score=258, Evalue=6e-70,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=27.2727272727273, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788627, Length=198, Percent_Identity=30.8080808080808, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787710, Length=375, Percent_Identity=26.4, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787909, Length=267, Percent_Identity=26.9662921348315, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=420, Percent_Identity=36.4285714285714, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI71994476, Length=420, Percent_Identity=36.4285714285714, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17567369, Length=408, Percent_Identity=30.3921568627451, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17567663, Length=355, Percent_Identity=23.6619718309859, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=393, Percent_Identity=30.7888040712468, Blast_Score=186, Evalue=8e-48,
Organism=Drosophila melanogaster, GI28573069, Length=414, Percent_Identity=35.5072463768116, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24646114, Length=414, Percent_Identity=35.5072463768116, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI28573067, Length=414, Percent_Identity=35.5072463768116, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI28573065, Length=414, Percent_Identity=35.5072463768116, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI18859735, Length=196, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 42209; Mature: 42078

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSRLRPYATTVFAEMSALATRIGAVNLGQGFPDEDGPPKMLQAAQDAIAGGVNQYPPG
CCCHHHCHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
PGSAPLRRAIAAQRRRHFGVDYDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYD
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEEECCCC
SYSPVVAMAGAHRVTVPLVPDGRGFALDADALRRAVTPRTRALIINSPHNPTGAVLSATE
CCCCCEEECCCCEEEEEECCCCCCCEECHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHH
LAAIAEIAVAANLVVITDEVYEHLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWK
HHHHHHHHHHHCEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCE
IGWACGPAELIAGVRAAKQYLSYVGGAPFQPAVALALDTEDAWVAALRNSLRARRDRLAA
EECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
GLTEIGFAVHDSYGTYFLCADPRPLGYDDSTEFCAALPEKVGVAAIPMSAFCDPAAGQAS
HHHHHHHEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCEEECCHHHCCCCCCCCCC
QQADVWNHLVRFTFCKRDDTLDEAIRRLSVLAERPAT
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TVSRLRPYATTVFAEMSALATRIGAVNLGQGFPDEDGPPKMLQAAQDAIAGGVNQYPPG
CCHHHCHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
PGSAPLRRAIAAQRRRHFGVDYDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYD
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEEECCCC
SYSPVVAMAGAHRVTVPLVPDGRGFALDADALRRAVTPRTRALIINSPHNPTGAVLSATE
CCCCCEEECCCCEEEEEECCCCCCCEECHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHH
LAAIAEIAVAANLVVITDEVYEHLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWK
HHHHHHHHHHHCEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCE
IGWACGPAELIAGVRAAKQYLSYVGGAPFQPAVALALDTEDAWVAALRNSLRARRDRLAA
EECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
GLTEIGFAVHDSYGTYFLCADPRPLGYDDSTEFCAALPEKVGVAAIPMSAFCDPAAGQAS
HHHHHHHEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCEEECCHHHCCCCCCCCCC
QQADVWNHLVRFTFCKRDDTLDEAIRRLSVLAERPAT
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]