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The map label for this gene is ptrB [H]

Identifier: 121636705

GI number: 121636705

Start: 906014

End: 908173

Strand: Direct

Name: ptrB [H]

Synonym: BCG_0833

Alternate gene names: 121636705

Gene position: 906014-908173 (Clockwise)

Preceding gene: 121636704

Following gene: 121636707

Centisome position: 20.71

GC content: 61.9

Gene sequence:

>2160_bases
ATGATGCACCGAACCGCACTACCCTCACCGCCCGTGGCCAAGCGGGTGCAGACCCGCCGGGAGCACCACGGCGACGTCTT
TGTCGACCCATATGAATGGTTGCGCGACAAGGACAGCCCTGAAGTAATCGCCTACCTCGAAGCTGAAAACGACTACACCG
AACGGACCACCGCGCACCTTGAGCCATTGCGGCAAAAGATCTTCCACGAAATCAAAGCGCGTACCAAGGAAACCGACTTA
TCGGTGCCGACGCGACGTGGCAACTGGTGGTACTACGCGCGGACCTTTGAGGGAAAGCAGTATGGCGTACACTGTCGTTG
CCCGGTAACCGATCCCGACGACTGGAACCCACCAGAGTTCGACGAGCGCACCGAAATACCCGGTGAACAGCTTCTGCTCG
ACGAGAACGTGGAAGCTGACGGCCACGACTTCTTCGCACTGGGCGCGGCCAGCGTCAGCCTGGACGATAACCTCTTAGCG
TATTCCGTTGATGTCGTAGGTGACGAACGATATACCTTGCGGTTCAAGGATTTACGCACCGGAGAACAGTACCCGGACGA
GATCGCCGGGATCGGAGCGGGAGTCACCTGGGCAGCTGACAACCGCACTGTCTACTACACCACCGTGGACGCGGCCTGGC
GTCCGGACACAGTGTGGCGATACCGACTAGGGTCCGGCGAATCGTCGGAGCGGGTTTACCACGAAGCCGATGATCGGTTC
TGGCTCGCGGTGGGGCGTACTCGCAGCAACGCCTATCTGCTGATTGCGGCGGGGTCGTCCATCACTTCGGAGGTCCGTTA
CGCGCACGCGGCAGATCCGACAGCGCAGTTCAGCGTGGTGCTGCCGCGCCGCGACGGCGTCGAGTACTCGGTGGAGCATG
CGGTCATAGCTGGCCAGGACCGGTTTCTGATCCTGCACAACGACGGCGCGGTGAACTTCACACTGGTAGAGGCCCCGGTC
GAGGATCCTGCGCGGCAACGCACCCTCATCGCCCACCGCGACGACGTCCGACTCGACGCGGTGGATGCCTTGGCCGGCCA
TCTGGTAGTCAGCTATCGGCGCGAGGCGCTGCCGCGGGTTCAACTGTGGCCGATCGGGCCTGACGGAAACTATGGTGAGC
CCGAAGAGATCTCGTTCGACTCCGAGCTGATGTCGGCCGGACTGGGGCCCAACCCCAACTGGGATTCGCCCAAACTGCGG
GTCGGTGCCGGATCTTTCGTCACCCCGGTGCGGATCTACGACATCGACCTGGTCACTGGCGAGCGTACCTTGCTGAAAGA
ACAGCCCGTACTGGGCGGCTACCGCCGCGAAGACTATGTGGAGCGGCGTGACTGGGCGTACGGAGACGACGGCACCCGGA
TCCCGGTCTCGATAGTGCACCGAGCCGATATCGAATTCCCGGCACCTGCGTTGATCTATGGCTACGGCGCCTACGAGATC
TGTGAGGATCCGCGGTTTTCCATCGCTCGGTTGTCGCTGCTGGATCGCGGGATGGTGTTCGTCGTCGCCCACGTTCGCGG
CGGCGGTGAGATGGGCAGGCTGTGGTATGAAAACGGCAAGCTACTGGACAAGAAGAACACGTTCACCGACTTCATCGCGG
TGGCAAGACATCTGGTGGACACGGGACTTACTTCCCAGCAGCAGCTGGTGGCATTGGGGGGTAGCGCGGGCGGTCTGCTG
ATGGGCGCGGTGGCCAACATGGCACCGGATCTCTTCGCCGGAATCCTTGCGCAGGTGCCGTTCGTGGACCCGCTGACCAC
CATCTTGGATCCATCGTTGCCGCTGACCGTCACCGAGTGGGACGAATGGGGAAATCCGTTGAACGACAGCGATGTCTATG
CCTATGTGAAATCGTATTCGCCGTACGAGAACGTCACGGCCCAAAAGTACCCGGCCATCCTGGCAATGACGTCGCTGAAC
GACACCAGGGTCTATTACGTGGAGCCGGCCAAGTGGGTGGCCGCGTTGCGGCACGCCAAGACCGACGGCAATTCCGTGCT
GTTGAAGACCCAGATGCACGCCGGTCATGGTGGGATCAGTGGCCGCTACGAGCGCTGGAAGGAGACCGCGTTTCAATACG
GGTGGTTGCTAGCTACTGCCGACAGCGACCGTTACGGCGGCGGCCAGGGAAACGACCTCGATGGCGCTGCGCCAGCATAG

Upstream 100 bases:

>100_bases
CGCTCCCCGAGCATATCGTCGAGGCCACGCGTGCCCGTTATATTAATGCATACGAACGGATTTCCGAACTAAAATTCGAC
GACTGGATCGGCCCTGGCGC

Downstream 100 bases:

>100_bases
CCGGTGGGATCGGCCATTCGGGATGCGTAGACATTGGCTCCGAACATGGCCAGCATCAGCGCCAGCGAGCATACCGCCGC
TGCCATGCGGGTGTCGGGCA

Product: putative protease II ptrB (oligopeptidase B)

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 719; Mature: 719

Protein sequence:

>719_residues
MMHRTALPSPPVAKRVQTRREHHGDVFVDPYEWLRDKDSPEVIAYLEAENDYTERTTAHLEPLRQKIFHEIKARTKETDL
SVPTRRGNWWYYARTFEGKQYGVHCRCPVTDPDDWNPPEFDERTEIPGEQLLLDENVEADGHDFFALGAASVSLDDNLLA
YSVDVVGDERYTLRFKDLRTGEQYPDEIAGIGAGVTWAADNRTVYYTTVDAAWRPDTVWRYRLGSGESSERVYHEADDRF
WLAVGRTRSNAYLLIAAGSSITSEVRYAHAADPTAQFSVVLPRRDGVEYSVEHAVIAGQDRFLILHNDGAVNFTLVEAPV
EDPARQRTLIAHRDDVRLDAVDALAGHLVVSYRREALPRVQLWPIGPDGNYGEPEEISFDSELMSAGLGPNPNWDSPKLR
VGAGSFVTPVRIYDIDLVTGERTLLKEQPVLGGYRREDYVERRDWAYGDDGTRIPVSIVHRADIEFPAPALIYGYGAYEI
CEDPRFSIARLSLLDRGMVFVVAHVRGGGEMGRLWYENGKLLDKKNTFTDFIAVARHLVDTGLTSQQQLVALGGSAGGLL
MGAVANMAPDLFAGILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLNDSDVYAYVKSYSPYENVTAQKYPAILAMTSLN
DTRVYYVEPAKWVAALRHAKTDGNSVLLKTQMHAGHGGISGRYERWKETAFQYGWLLATADSDRYGGGQGNDLDGAAPA

Sequences:

>Translated_719_residues
MMHRTALPSPPVAKRVQTRREHHGDVFVDPYEWLRDKDSPEVIAYLEAENDYTERTTAHLEPLRQKIFHEIKARTKETDL
SVPTRRGNWWYYARTFEGKQYGVHCRCPVTDPDDWNPPEFDERTEIPGEQLLLDENVEADGHDFFALGAASVSLDDNLLA
YSVDVVGDERYTLRFKDLRTGEQYPDEIAGIGAGVTWAADNRTVYYTTVDAAWRPDTVWRYRLGSGESSERVYHEADDRF
WLAVGRTRSNAYLLIAAGSSITSEVRYAHAADPTAQFSVVLPRRDGVEYSVEHAVIAGQDRFLILHNDGAVNFTLVEAPV
EDPARQRTLIAHRDDVRLDAVDALAGHLVVSYRREALPRVQLWPIGPDGNYGEPEEISFDSELMSAGLGPNPNWDSPKLR
VGAGSFVTPVRIYDIDLVTGERTLLKEQPVLGGYRREDYVERRDWAYGDDGTRIPVSIVHRADIEFPAPALIYGYGAYEI
CEDPRFSIARLSLLDRGMVFVVAHVRGGGEMGRLWYENGKLLDKKNTFTDFIAVARHLVDTGLTSQQQLVALGGSAGGLL
MGAVANMAPDLFAGILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLNDSDVYAYVKSYSPYENVTAQKYPAILAMTSLN
DTRVYYVEPAKWVAALRHAKTDGNSVLLKTQMHAGHGGISGRYERWKETAFQYGWLLATADSDRYGGGQGNDLDGAAPA
>Mature_719_residues
MMHRTALPSPPVAKRVQTRREHHGDVFVDPYEWLRDKDSPEVIAYLEAENDYTERTTAHLEPLRQKIFHEIKARTKETDL
SVPTRRGNWWYYARTFEGKQYGVHCRCPVTDPDDWNPPEFDERTEIPGEQLLLDENVEADGHDFFALGAASVSLDDNLLA
YSVDVVGDERYTLRFKDLRTGEQYPDEIAGIGAGVTWAADNRTVYYTTVDAAWRPDTVWRYRLGSGESSERVYHEADDRF
WLAVGRTRSNAYLLIAAGSSITSEVRYAHAADPTAQFSVVLPRRDGVEYSVEHAVIAGQDRFLILHNDGAVNFTLVEAPV
EDPARQRTLIAHRDDVRLDAVDALAGHLVVSYRREALPRVQLWPIGPDGNYGEPEEISFDSELMSAGLGPNPNWDSPKLR
VGAGSFVTPVRIYDIDLVTGERTLLKEQPVLGGYRREDYVERRDWAYGDDGTRIPVSIVHRADIEFPAPALIYGYGAYEI
CEDPRFSIARLSLLDRGMVFVVAHVRGGGEMGRLWYENGKLLDKKNTFTDFIAVARHLVDTGLTSQQQLVALGGSAGGLL
MGAVANMAPDLFAGILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLNDSDVYAYVKSYSPYENVTAQKYPAILAMTSLN
DTRVYYVEPAKWVAALRHAKTDGNSVLLKTQMHAGHGGISGRYERWKETAFQYGWLLATADSDRYGGGQGNDLDGAAPA

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=713, Percent_Identity=24.9649368863955, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI284172420, Length=484, Percent_Identity=28.7190082644628, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI284172413, Length=484, Percent_Identity=28.7190082644628, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI70778815, Length=484, Percent_Identity=28.7190082644628, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI284172438, Length=502, Percent_Identity=28.2868525896414, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI284172431, Length=502, Percent_Identity=28.2868525896414, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI108860686, Length=302, Percent_Identity=33.4437086092715, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI108860692, Length=223, Percent_Identity=39.0134529147982, Blast_Score=132, Evalue=1e-30,
Organism=Escherichia coli, GI1788150, Length=696, Percent_Identity=38.2183908045977, Blast_Score=456, Evalue=1e-129,
Organism=Drosophila melanogaster, GI24583414, Length=710, Percent_Identity=26.7605633802817, Blast_Score=201, Evalue=2e-51,
Organism=Drosophila melanogaster, GI221510989, Length=701, Percent_Identity=25.8202567760342, Blast_Score=179, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 80382; Mature: 80382

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHRTALPSPPVAKRVQTRREHHGDVFVDPYEWLRDKDSPEVIAYLEAENDYTERTTAHL
CCCCCCCCCCHHHHHHHHHHHHCCCEEECHHHHHCCCCCCCEEEEEECCCCCCHHHHHHH
EPLRQKIFHEIKARTKETDLSVPTRRGNWWYYARTFEGKQYGVHCRCPVTDPDDWNPPEF
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCEECEEEECCCCCCCCCCCCCC
DERTEIPGEQLLLDENVEADGHDFFALGAASVSLDDNLLAYSVDVVGDERYTLRFKDLRT
CCCCCCCCHHEEEECCCCCCCCEEEEEEEEEEEECCCEEEEEEEEECCCEEEEEEEECCC
GEQYPDEIAGIGAGVTWAADNRTVYYTTVDAAWRPDTVWRYRLGSGESSERVYHEADDRF
CCCCCHHHHHCCCCEEEECCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCEECCCCEE
WLAVGRTRSNAYLLIAAGSSITSEVRYAHAADPTAQFSVVLPRRDGVEYSVEHAVIAGQD
EEEEECCCCCEEEEEECCCCHHHHHHEEECCCCCCEEEEEEECCCCCCEEEEEEEEECCC
RFLILHNDGAVNFTLVEAPVEDPARQRTLIAHRDDVRLDAVDALAGHLVVSYRREALPRV
CEEEEECCCCEEEEEEECCCCCCHHHCEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCCE
QLWPIGPDGNYGEPEEISFDSELMSAGLGPNPNWDSPKLRVGAGSFVTPVRIYDIDLVTG
EEEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEECCCCCCCEEEEEEEEEECC
ERTLLKEQPVLGGYRREDYVERRDWAYGDDGTRIPVSIVHRADIEFPAPALIYGYGAYEI
CHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCEEEEECCCHHH
CEDPRFSIARLSLLDRGMVFVVAHVRGGGEMGRLWYENGKLLDKKNTFTDFIAVARHLVD
CCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCCEEEECCCCHHHHHHHHHHHHH
TGLTSQQQLVALGGSAGGLLMGAVANMAPDLFAGILAQVPFVDPLTTILDPSLPLTVTEW
CCCCCCCEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHCCCCCEEEECH
DEWGNPLNDSDVYAYVKSYSPYENVTAQKYPAILAMTSLNDTRVYYVEPAKWVAALRHAK
HHCCCCCCCCCEEEEEECCCCCCCCCHHHCCEEEEEEECCCCEEEEECHHHHHHHHHHCC
TDGNSVLLKTQMHAGHGGISGRYERWKETAFQYGWLLATADSDRYGGGQGNDLDGAAPA
CCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMHRTALPSPPVAKRVQTRREHHGDVFVDPYEWLRDKDSPEVIAYLEAENDYTERTTAHL
CCCCCCCCCCHHHHHHHHHHHHCCCEEECHHHHHCCCCCCCEEEEEECCCCCCHHHHHHH
EPLRQKIFHEIKARTKETDLSVPTRRGNWWYYARTFEGKQYGVHCRCPVTDPDDWNPPEF
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCEECEEEECCCCCCCCCCCCCC
DERTEIPGEQLLLDENVEADGHDFFALGAASVSLDDNLLAYSVDVVGDERYTLRFKDLRT
CCCCCCCCHHEEEECCCCCCCCEEEEEEEEEEEECCCEEEEEEEEECCCEEEEEEEECCC
GEQYPDEIAGIGAGVTWAADNRTVYYTTVDAAWRPDTVWRYRLGSGESSERVYHEADDRF
CCCCCHHHHHCCCCEEEECCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCEECCCCEE
WLAVGRTRSNAYLLIAAGSSITSEVRYAHAADPTAQFSVVLPRRDGVEYSVEHAVIAGQD
EEEEECCCCCEEEEEECCCCHHHHHHEEECCCCCCEEEEEEECCCCCCEEEEEEEEECCC
RFLILHNDGAVNFTLVEAPVEDPARQRTLIAHRDDVRLDAVDALAGHLVVSYRREALPRV
CEEEEECCCCEEEEEEECCCCCCHHHCEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCCE
QLWPIGPDGNYGEPEEISFDSELMSAGLGPNPNWDSPKLRVGAGSFVTPVRIYDIDLVTG
EEEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEECCCCCCCEEEEEEEEEECC
ERTLLKEQPVLGGYRREDYVERRDWAYGDDGTRIPVSIVHRADIEFPAPALIYGYGAYEI
CHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCEEEEECCCHHH
CEDPRFSIARLSLLDRGMVFVVAHVRGGGEMGRLWYENGKLLDKKNTFTDFIAVARHLVD
CCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCCEEEECCCCHHHHHHHHHHHHH
TGLTSQQQLVALGGSAGGLLMGAVANMAPDLFAGILAQVPFVDPLTTILDPSLPLTVTEW
CCCCCCCEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHCCCCCEEEECH
DEWGNPLNDSDVYAYVKSYSPYENVTAQKYPAILAMTSLNDTRVYYVEPAKWVAALRHAK
HHCCCCCCCCCEEEEEECCCCCCCCCHHHCCEEEEEEECCCCEEEEECHHHHHHHHHHCC
TDGNSVLLKTQMHAGHGGISGRYERWKETAFQYGWLLATADSDRYGGGQGNDLDGAAPA
CCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]