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The map label for this gene is 121636414

Identifier: 121636414

GI number: 121636414

Start: 618175

End: 619107

Strand: Direct

Name: 121636414

Synonym: BCG_0539

Alternate gene names: NA

Gene position: 618175-619107 (Clockwise)

Preceding gene: 121636413

Following gene: 121636415

Centisome position: 14.13

GC content: 68.92

Gene sequence:

>933_bases
ATGACGGGACCACACCCCGAAACAGAGAGCTCCGGTAACCGGCAGATCTCGGTGGCCGAGTTGCTGGCCAGGCAAGGGGT
CACCGGCGCCCCGGCCCGACGGCGCCGGCGGCGACGCGGCGATAGTGACGCCATCACGGTCGCCGAGCTGACCGGTGAGA
TTCCGATCATTCGTGACGACCATCACCACGCCGGCCCGGACGCGCACGCGAGCCAGTCTCCGGCGGCTAACGGGCGAGTC
CAGGTTGGCGAAGCTGCCCCACAGTCGCCGGCGGAACCAGTCGCCGAGCAGGTTGCCGAAGAGCCAACGAGAACCGTGTA
CTGGTCGCAACCCGAGCCGCGCTGGCCCAAGTCCCCCCCGCAGGACCGGCGCGAGTCCGGGCCCGAGCTTAGCGAGTACC
CGCGGCCACTGCGCCACACGCATAGCGACAGAGCACCCGCGGGGCCGCCGTCCGGTGCCGAACACATGAGTCCGGATCCG
GTCGAGCACTACCCCGATCTCTGGGTGGATGTCCTGGACACCGAGGTGGGCGAAGCGGAAGCCGAGACCGAGGTGCGCGA
AGCGCAACCTGGGCGCGGCGAGCGCCACGCCGCAGCGGCTGCGGCCGGCACCGACGTCGAGGGTGATGGTGCGGCCGAGG
CGCGGGTTGCCCGTCGTGCCCTGGACGTGGTCCCGACGCTGTGGCGCGGCGCGTTGGTCGTGCTGCAGTCGATCCTGGCC
GTTGCCTTCGGTGCCGGGTTGTTCATCGCCTTCGACCAGTTGTGGCGCTGGAACAGCATAGTGGCGCTAGTGCTATCGGT
GATGGTCATCCTTGGCCTAGTGGTCTCGGTGCGGGCAGTCCGCAAGACCGAAGACATCGCCAGTACGTTGATCGCGGTTG
CGGTGGGGGCGCTGATTACCCTGGGACCGCTGGCCTTGTTGCAATCGGGCTAG

Upstream 100 bases:

>100_bases
CCGCCCTCATCGAGTCTTCGTCTGTGCACACTTCGGTGCGTGCCGTCGGAGGTCAGCCAGCTGATCGGAACGCGGCCAAC
CGATCGAGAGGCAGCAAACC

Downstream 100 bases:

>100_bases
CCGCCACCACACACAGTGCGCCCAGCAATCAAAGTCGGCTTGTCGACGGCCTCGGTGTACCCGTTGCGGGCCGAGGCCGC
GTTCGAGTACGCCGACAGGC

Product: putative transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTGPHPETESSGNRQISVAELLARQGVTGAPARRRRRRRGDSDAITVAELTGEIPIIRDDHHHAGPDAHASQSPAANGRV
QVGEAAPQSPAEPVAEQVAEEPTRTVYWSQPEPRWPKSPPQDRRESGPELSEYPRPLRHTHSDRAPAGPPSGAEHMSPDP
VEHYPDLWVDVLDTEVGEAEAETEVREAQPGRGERHAAAAAAGTDVEGDGAAEARVARRALDVVPTLWRGALVVLQSILA
VAFGAGLFIAFDQLWRWNSIVALVLSVMVILGLVVSVRAVRKTEDIASTLIAVAVGALITLGPLALLQSG

Sequences:

>Translated_310_residues
MTGPHPETESSGNRQISVAELLARQGVTGAPARRRRRRRGDSDAITVAELTGEIPIIRDDHHHAGPDAHASQSPAANGRV
QVGEAAPQSPAEPVAEQVAEEPTRTVYWSQPEPRWPKSPPQDRRESGPELSEYPRPLRHTHSDRAPAGPPSGAEHMSPDP
VEHYPDLWVDVLDTEVGEAEAETEVREAQPGRGERHAAAAAAGTDVEGDGAAEARVARRALDVVPTLWRGALVVLQSILA
VAFGAGLFIAFDQLWRWNSIVALVLSVMVILGLVVSVRAVRKTEDIASTLIAVAVGALITLGPLALLQSG
>Mature_309_residues
TGPHPETESSGNRQISVAELLARQGVTGAPARRRRRRRGDSDAITVAELTGEIPIIRDDHHHAGPDAHASQSPAANGRVQ
VGEAAPQSPAEPVAEQVAEEPTRTVYWSQPEPRWPKSPPQDRRESGPELSEYPRPLRHTHSDRAPAGPPSGAEHMSPDPV
EHYPDLWVDVLDTEVGEAEAETEVREAQPGRGERHAAAAAAGTDVEGDGAAEARVARRALDVVPTLWRGALVVLQSILAV
AFGAGLFIAFDQLWRWNSIVALVLSVMVILGLVVSVRAVRKTEDIASTLIAVAVGALITLGPLALLQSG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML2433

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y497_MYCTU (P64715)

Other databases:

- EMBL:   BX842573
- EMBL:   AE000516
- PIR:   D70745
- RefSeq:   NP_215011.1
- RefSeq:   NP_334926.1
- EnsemblBacteria:   EBMYCT00000000228
- EnsemblBacteria:   EBMYCT00000071752
- GeneID:   887240
- GeneID:   923893
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0517
- KEGG:   mtu:Rv0497
- TIGR:   MT0517
- TubercuList:   Rv0497
- GeneTree:   EBGT00050000014853
- HOGENOM:   HBG569847
- OMA:   YWSEPEP
- ProtClustDB:   CLSK790558

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 33092; Mature: 32961

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13116ce8)-; HASH(0x14063dc0)-; HASH(0x1321ce6c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGPHPETESSGNRQISVAELLARQGVTGAPARRRRRRRGDSDAITVAELTGEIPIIRDD
CCCCCCCCCCCCCCEEHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEHHHHCCCCCEEECC
HHHAGPDAHASQSPAANGRVQVGEAAPQSPAEPVAEQVAEEPTRTVYWSQPEPRWPKSPP
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCC
QDRRESGPELSEYPRPLRHTHSDRAPAGPPSGAEHMSPDPVEHYPDLWVDVLDTEVGEAE
HHHHHCCCCHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
AETEVREAQPGRGERHAAAAAAGTDVEGDGAAEARVARRALDVVPTLWRGALVVLQSILA
HHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAFGAGLFIAFDQLWRWNSIVALVLSVMVILGLVVSVRAVRKTEDIASTLIAVAVGALIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGPLALLQSG
HHHHHHHCCH
>Mature Secondary Structure 
TGPHPETESSGNRQISVAELLARQGVTGAPARRRRRRRGDSDAITVAELTGEIPIIRDD
CCCCCCCCCCCCCEEHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEHHHHCCCCCEEECC
HHHAGPDAHASQSPAANGRVQVGEAAPQSPAEPVAEQVAEEPTRTVYWSQPEPRWPKSPP
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCC
QDRRESGPELSEYPRPLRHTHSDRAPAGPPSGAEHMSPDPVEHYPDLWVDVLDTEVGEAE
HHHHHCCCCHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
AETEVREAQPGRGERHAAAAAAGTDVEGDGAAEARVARRALDVVPTLWRGALVVLQSILA
HHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAFGAGLFIAFDQLWRWNSIVALVLSVMVILGLVVSVRAVRKTEDIASTLIAVAVGALIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGPLALLQSG
HHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036