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The map label for this gene is regX3 [H]

Identifier: 121636407

GI number: 121636407

Start: 611607

End: 612290

Strand: Direct

Name: regX3 [H]

Synonym: BCG_0532

Alternate gene names: 121636407

Gene position: 611607-612290 (Clockwise)

Preceding gene: 121636406

Following gene: 121636411

Centisome position: 13.98

GC content: 64.18

Gene sequence:

>684_bases
ATGACCAGTGTGTTGATTGTGGAGGACGAGGAGTCGCTGGCCGATCCGCTGACGTTTCTGCTGCGCAAGGAGGGCTTTGA
GGCCACGGTGGTGACCGATGGTCCGGCAGCTCTCGCCGAGTTCGACCGGGCCGGCGCCGACATCGTCCTGCTCGATCTGA
TGCTGCCTGGGATGTCGGGTACCGATGTATGCAAGCAGTTGCGCGCTCGGTCCAGCGTTCCGGTGATCATGGTGACCGCC
CGGGATAGCGAGATCGACAAGGTGGTCGGCCTGGAGCTGGGCGCTGACGACTACGTGACCAAGCCCTATTCGGCACGCGA
GTTGATCGCACGCATCCGCGCGGTGCTGCGCCGTGGCGGCGACGACGACTCGGAGATGAGCGATGGCGTGCTGGAGTCCG
GGCCGGTTCGCATGGATGTGGAGCGCCATGTCGTCTCGGTGAACGGTGACACCATCACGCTGCCGCTCAAGGAGTTCGAC
CTGCTGGAATACCTGATGCGCAACAGCGGGCGGGTGTTGACTCGCGGACAACTGATCGACCGGGTCTGGGGTGCGGACTA
CGTGGGCGACACCAAGACGCTCGACGTCCATGTCAAGCGGCTGCGCTCCAAGATCGAAGCCGACCCGGCTAACCCGGTTC
ACTTGGTGACGGTGCGCGGGCTGGGCTACAAACTCGAGGGCTAG

Upstream 100 bases:

>100_bases
GCTTGCGGGGGAGAGTGGCGCTGATGACCTGCGCCGACGACGATGCAGAGCGTAGCGATGAGGTGGGGGCACCACCCGCT
TGCGGGGGAGAGTGGCGCTG

Downstream 100 bases:

>100_bases
CGGACGCCGACAACCTTGGCGACTGTCTGGTCGGCTACGGCCAGTGCCATCGCCATGATGGACAGCTGCGGGTTCACTTC
CGGGCAGCTGGGCAGGATCG

Product: two component sensory transduction protein RegX3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTSVLIVEDEESLADPLTFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTA
RDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFD
LLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG

Sequences:

>Translated_227_residues
MTSVLIVEDEESLADPLTFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTA
RDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFD
LLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
>Mature_226_residues
TSVLIVEDEESLADPLTFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTAR
DSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDL
LEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=39.647577092511, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=38.8392857142857, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=38.0530973451327, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=36, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=38.5964912280702, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=37.8378378378378, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=38.6666666666667, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=37.5, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=32.3275862068966, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=39.2070484581498, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=35.6828193832599, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=34.375, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=34.8214285714286, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=31.6017316017316, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=34.8623853211009, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24880; Mature: 24749

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVLIVEDEESLADPLTFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG
CCEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCEEEEEECCCCCCH
TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
HHHHHHHHHCCCCCEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID
CCCHHHHCCCCCCCCEEEEEEEEEEEECCCEEEEEHHHHHHHHHHHHCCCCEEEHHHHHH
RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEECC
>Mature Secondary Structure 
TSVLIVEDEESLADPLTFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG
CEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCEEEEEECCCCCCH
TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
HHHHHHHHHCCCCCEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID
CCCHHHHCCCCCCCCEEEEEEEEEEEECCCEEEEEHHHHHHHHHHHHCCCCEEEHHHHHH
RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA