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The map label for this gene is lpqL [H]

Identifier: 121636332

GI number: 121636332

Start: 534311

End: 535813

Strand: Direct

Name: lpqL [H]

Synonym: BCG_0457

Alternate gene names: 121636332

Gene position: 534311-535813 (Clockwise)

Preceding gene: 121636331

Following gene: 121636333

Centisome position: 12.21

GC content: 64.67

Gene sequence:

>1503_bases
ATGGTGAACAAATCCAGGATGATGCCGGCGGTGCTGGCCGTGGCTGTGGTCGTCGCATTCCTGACGACGGGCTGTATCCG
GTGGTCTACGCAGTCGCGGCCCGTTGTTAACGGCCCCGCTGCCGCAGAGTTCGCCGTTGCGTTGCGCAACCGGGTGAGCA
CCGACGCGATGATGGCGCACCTATCGAAACTGCAGGACATCGCCAACGCCAACGACGGCACTCGCGCGGTGGGCACCCCT
GGCTATCAGGCCAGCGTCGACTATGTGGTAAACACACTGCGCAACAGCGGTTTTGATGTGCAAACCCCGGAGTTCTCCGC
TCGCGTGTTCAAGGCCGAAAAAGGGGTGGTGACCCTCGGCGGCAACACCGTGGAGGCGAGGGCGCTCGAGTACAGCCTCG
GCACACCGCCGGACGGGGTGACGGGCCCGCTGGTGGCTGCCCCCGCCGACGACAGTCCGGGCTGCAGTCCGTCGGACTAC
GACAGGCTGCCGGTGTCCGGTGCGGTGGTGCTGGTAGATCGCGGCGTCTGTCCTTTTGCCCAGAAGGAAGACGCAGCCGC
GCAGCGCGGTGCGGTGGCGCTGATCATTGCTGACAACATCGACGAGCAGGCGATGGGCGGCACCCTGGGGGCTAATACCG
ACGTCAAGATCCCGGTGGTGAGTGTCACCAAGTCGGTCGGATTCCAGCTACGCGGACAGTCTGGGCCAACCACCGTCAAG
CTCACGGCGAGCACCCAAAGTTTCAAGGCCCGCAACGTCATCGCGCAGACGAAGACGGGGTCGTCGGCCAACGTGGTGAT
GGCAGGTGCGCATTTGGACAGCGTTCCGGAAGGACCCGGCATCAACGACAACGGCTCGGGAGTGGCTGCGGTTCTGGAAA
CGGCAGTGCAGCTGGGGAACTCACCGCATGTGTCCAACGCGGTACGGTTCGCCTTCTGGGGCGCCGAGGAATTCGGCCTG
ATTGGGTCACGAAACTACGTCGAGTCGCTGGACATCGACGCGCTCAAAGGCATCGCGCTGTATCTGAACTTCGACATGTT
GGCGTCGCCGAACCCGGGTTACTTCACCTACGACGGTGACCAGTCGCTGCCGCTAGACGCCCGCGGTCAGCCGGTGGTGC
CCGAAGGCTCGGCCGGTATCGAGCGCACGTTCGTCGCCTATCTGAAGATGGCCGGCAAGACCGCGCAGGACACCTCGTTC
GACGGTCGGTCCGACTACGACGGCTTCACGCTGGCGGGTATCCCTTCGGGTGGCCTGTTCTCCGGCGCTGAGGTCAAGAA
GTCCGCCGAGCAAGCCGAGCTCTGGGGCGGCACCGCCGACGAGCCTTTCGATCCCAACTATCACCAGAAGACAGACACCC
TGGACCATATCGACCGCACCGCGCTCGGTATCAACGGCGCTGGCGTCGCGTACGCGGTGGGTTTGTATGCGCAGGACCTC
GGCGGCCCCAACGGGGTTCCGGTCATGGCGGACCGCACCCGCCACCTGATTGCCAAACCGTGA

Upstream 100 bases:

>100_bases
TGTGTAACCTCCGGTTTAGGCCATTCAACGCTCTGTTCGTTTGATTGGTCGGTGGGATGCGAAAGCTGCGCGGCGACAGG
CGCGGTCTAATCTGGGCGCG

Downstream 100 bases:

>100_bases
TCCGGGCCTGATCTCGCCACTGACCCCGCACCGACCGATCTAGAATGGGATTTCCTTGGTGCATGCCGGGCGGGACGGGG
TTAGGAGATGCATGGTCGCG

Product: putative lipoprotein aminopeptidase lpqL

Products: NA

Alternate protein names: LIE1 [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MVNKSRMMPAVLAVAVVVAFLTTGCIRWSTQSRPVVNGPAAAEFAVALRNRVSTDAMMAHLSKLQDIANANDGTRAVGTP
GYQASVDYVVNTLRNSGFDVQTPEFSARVFKAEKGVVTLGGNTVEARALEYSLGTPPDGVTGPLVAAPADDSPGCSPSDY
DRLPVSGAVVLVDRGVCPFAQKEDAAAQRGAVALIIADNIDEQAMGGTLGANTDVKIPVVSVTKSVGFQLRGQSGPTTVK
LTASTQSFKARNVIAQTKTGSSANVVMAGAHLDSVPEGPGINDNGSGVAAVLETAVQLGNSPHVSNAVRFAFWGAEEFGL
IGSRNYVESLDIDALKGIALYLNFDMLASPNPGYFTYDGDQSLPLDARGQPVVPEGSAGIERTFVAYLKMAGKTAQDTSF
DGRSDYDGFTLAGIPSGGLFSGAEVKKSAEQAELWGGTADEPFDPNYHQKTDTLDHIDRTALGINGAGVAYAVGLYAQDL
GGPNGVPVMADRTRHLIAKP

Sequences:

>Translated_500_residues
MVNKSRMMPAVLAVAVVVAFLTTGCIRWSTQSRPVVNGPAAAEFAVALRNRVSTDAMMAHLSKLQDIANANDGTRAVGTP
GYQASVDYVVNTLRNSGFDVQTPEFSARVFKAEKGVVTLGGNTVEARALEYSLGTPPDGVTGPLVAAPADDSPGCSPSDY
DRLPVSGAVVLVDRGVCPFAQKEDAAAQRGAVALIIADNIDEQAMGGTLGANTDVKIPVVSVTKSVGFQLRGQSGPTTVK
LTASTQSFKARNVIAQTKTGSSANVVMAGAHLDSVPEGPGINDNGSGVAAVLETAVQLGNSPHVSNAVRFAFWGAEEFGL
IGSRNYVESLDIDALKGIALYLNFDMLASPNPGYFTYDGDQSLPLDARGQPVVPEGSAGIERTFVAYLKMAGKTAQDTSF
DGRSDYDGFTLAGIPSGGLFSGAEVKKSAEQAELWGGTADEPFDPNYHQKTDTLDHIDRTALGINGAGVAYAVGLYAQDL
GGPNGVPVMADRTRHLIAKP
>Mature_500_residues
MVNKSRMMPAVLAVAVVVAFLTTGCIRWSTQSRPVVNGPAAAEFAVALRNRVSTDAMMAHLSKLQDIANANDGTRAVGTP
GYQASVDYVVNTLRNSGFDVQTPEFSARVFKAEKGVVTLGGNTVEARALEYSLGTPPDGVTGPLVAAPADDSPGCSPSDY
DRLPVSGAVVLVDRGVCPFAQKEDAAAQRGAVALIIADNIDEQAMGGTLGANTDVKIPVVSVTKSVGFQLRGQSGPTTVK
LTASTQSFKARNVIAQTKTGSSANVVMAGAHLDSVPEGPGINDNGSGVAAVLETAVQLGNSPHVSNAVRFAFWGAEEFGL
IGSRNYVESLDIDALKGIALYLNFDMLASPNPGYFTYDGDQSLPLDARGQPVVPEGSAGIERTFVAYLKMAGKTAQDTSF
DGRSDYDGFTLAGIPSGGLFSGAEVKKSAEQAELWGGTADEPFDPNYHQKTDTLDHIDRTALGINGAGVAYAVGLYAQDL
GGPNGVPVMADRTRHLIAKP

Specific function: A leucine-specific metalloprotease that plays a role in controlling the amount of leupeptin during colony development. Degrades leupeptin into three components, acetyl-leucine, leucine and argininal [H]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M28 family. M28A subfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319763, Length=458, Percent_Identity=31.6593886462882, Blast_Score=206, Evalue=8e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR007484
- InterPro:   IPR002884 [H]

Pfam domain/function: PF01483 P_proprotein; PF04389 Peptidase_M28 [H]

EC number: NA

Molecular weight: Translated: 52043; Mature: 52043

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKSRMMPAVLAVAVVVAFLTTGCIRWSTQSRPVVNGPAAAEFAVALRNRVSTDAMMAH
CCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHH
LSKLQDIANANDGTRAVGTPGYQASVDYVVNTLRNSGFDVQTPEFSARVFKAEKGVVTLG
HHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHEEEECCCCEEEEC
GNTVEARALEYSLGTPPDGVTGPLVAAPADDSPGCSPSDYDRLPVSGAVVLVDRGVCPFA
CCEEEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
QKEDAAAQRGAVALIIADNIDEQAMGGTLGANTDVKIPVVSVTKSVGFQLRGQSGPTTVK
CCCHHHHHCCCEEEEEECCCCHHHCCCCCCCCCCEEEEEEEEECCCCEEEECCCCCEEEE
LTASTQSFKARNVIAQTKTGSSANVVMAGAHLDSVPEGPGINDNGSGVAAVLETAVQLGN
EEECCCCHHHHHHEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
SPHVSNAVRFAFWGAEEFGLIGSRNYVESLDIDALKGIALYLNFDMLASPNPGYFTYDGD
CCCCCCEEEEEEECCHHHCCCCCCCHHHHCCHHHHCCEEEEEEEEEECCCCCCEEEECCC
QSLPLDARGQPVVPEGSAGIERTFVAYLKMAGKTAQDTSFDGRSDYDGFTLAGIPSGGLF
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCC
SGAEVKKSAEQAELWGGTADEPFDPNYHQKTDTLDHIDRTALGINGAGVAYAVGLYAQDL
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHC
GGPNGVPVMADRTRHLIAKP
CCCCCCCEEECCCCHHCCCC
>Mature Secondary Structure
MVNKSRMMPAVLAVAVVVAFLTTGCIRWSTQSRPVVNGPAAAEFAVALRNRVSTDAMMAH
CCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHH
LSKLQDIANANDGTRAVGTPGYQASVDYVVNTLRNSGFDVQTPEFSARVFKAEKGVVTLG
HHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHEEEECCCCEEEEC
GNTVEARALEYSLGTPPDGVTGPLVAAPADDSPGCSPSDYDRLPVSGAVVLVDRGVCPFA
CCEEEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
QKEDAAAQRGAVALIIADNIDEQAMGGTLGANTDVKIPVVSVTKSVGFQLRGQSGPTTVK
CCCHHHHHCCCEEEEEECCCCHHHCCCCCCCCCCEEEEEEEEECCCCEEEECCCCCEEEE
LTASTQSFKARNVIAQTKTGSSANVVMAGAHLDSVPEGPGINDNGSGVAAVLETAVQLGN
EEECCCCHHHHHHEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
SPHVSNAVRFAFWGAEEFGLIGSRNYVESLDIDALKGIALYLNFDMLASPNPGYFTYDGD
CCCCCCEEEEEEECCHHHCCCCCCCHHHHCCHHHHCCEEEEEEEEEECCCCCCEEEECCC
QSLPLDARGQPVVPEGSAGIERTFVAYLKMAGKTAQDTSFDGRSDYDGFTLAGIPSGGLF
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCC
SGAEVKKSAEQAELWGGTADEPFDPNYHQKTDTLDHIDRTALGINGAGVAYAVGLYAQDL
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHC
GGPNGVPVMADRTRHLIAKP
CCCCCCCEEECCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA