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The map label for this gene is pta [H]

Identifier: 121636322

GI number: 121636322

Start: 522601

End: 524673

Strand: Direct

Name: pta [H]

Synonym: BCG_0447

Alternate gene names: 121636322

Gene position: 522601-524673 (Clockwise)

Preceding gene: 121636321

Following gene: 121636323

Centisome position: 11.95

GC content: 64.21

Gene sequence:

>2073_bases
TTGGCTGACTCCTCGGCGATCTACCTCGCCGCACCAGAATCGCAGACGGGTAAGTCGACGATTGCACTGGGGCTTTTGCA
CCGACTGACCGCGATGGTCGCCAAAGTCGGTGTGTTCCGGCCGATTACGCGGCTCTCTGCGGAGCGGGACTACATCCTGG
AACTACTGCTCGCGCACACCAGTGCGGGCCTGCCCTATGAGCGGTGTGTTGGCGTGACCTACCAGCAGCTGCATGCTGAC
CGCGACGACGCGATCGCCGAAATTGTCGATTCGTATCACGCAATGGCCGACGAGTGTGACGCGGTGGTGGTCGTCGGCAG
TGACTACACCGACGTCACCAGCCCCACCGAGCTCTCGGTCAACGCCCGGATCGCGGTGAACCTCGGCGCGCCAGTGTTGT
TGACGGTTCGGGCGAAGGACCGCACCCCCGATCAGGTCGCCAGCGTCGTCGAGGTCTGCTTGGCCGAGCTGGACACCCAG
CGCGCTCATACCGCGGCGGTAGTGGCGAACCGGTGCGAGCTGTCCGCGATACCGGCCGTGACCGACGCGCTGCGCAGGTT
CACCCCGCCTAGCTATGTAGTGCCCGAGGAACCACTGCTGTCGGCGCCGACCGTTGCCGAGTTAACGCAGGCTGTGAACG
GGGCGGTGGTAAGCGGTGATGTTGCGCTGCGCGAACGTGAGGTGATGGGCGTGCTGGCCGCGGGTATGACCGCCGACCAT
GTGTTGGAGCGGCTGACCGATGGCATGGCGGTGATTACTCCCGGCGACCGCTCGGACGTGGTGTTGGCCGTCGCTAGCGC
CCATGCGGCCGAAGGGTTTCCGTCATTGTCATGCATCGTCCTCAATGGCGGGTTCCAGTTGCATCCGGCGATCGCCGCCC
TGGTTTCCGGCCTGCGATTGCGGTTACCTGTCATCGCCACCGCGTTGGGCACCTACGACACCGCCAGCGCTGCCGCGTCG
GCCCGCGGGCTGGTAACGGCGACGTCGCAACGCAAGATCGACACCGCGTTGGAGCTGATGGACCGCCACGTGGACGTCGC
CGGTCTATTGGCGCAGCTGACCATTCCCATCCCTACGGTCACTACACCACAGATGTTCACTTATCGGCTGCTGCAGCAGG
CCCGTTCGGACCTCATGCGCATCGTCCTTCCCGAAGGGGACGACGATCGCATCCTCAAATCGGCGGGCCGCCTGCTTCAG
CGCGGCATCGTCGACCTGACCATCCTGGGCGATGAAGCCAAAGTCCGTCTGCGGGCAGCGGAACTCGGTGTGGACCTGGA
CGGCGCCACGGTAATCGAGCCATGCGCAAGCGAACTGCACGATCAATTCGCCGACCAGTATGCGCAGTTGCGTAAGGCGA
AGGGAATCACCGTGGAGCATGCCCGCGAAATCATGAACGATGCCACATATTTCGGCACCATGCTGGTGCACAACTGTCAT
GCCGACGGCATGGTATCGGGTGCTGCTCACACCACGGCGCACACCGTTCGTCCGGCGCTGGAGATCATCAAGACCGTTCC
GGGCATATCCACCGTGTCCAGCATTTTCCTGATGTGTCTGCCGGATCGGGTACTGGCGTACGGCGACTGCGCGATCATCC
CGAACCCGACGGTGGAGCAGCTCGCTGATATCGCCATCTGCTCGGCACGCACCGCCGCACAGTTCGGCATCGAGCCCCGG
GTGGCCATGCTGTCCTACTCCACCGGTGACTCGGGGAAAGGTGCCGACGTCGACAAGGTCAGAGCGGCAACGGAGTTGGT
GCGCGCTCGGGAGCCGCAGCTGCCGGTCGAGGGTCCCATTCAATACGACGCCGCAGTGGAACCGTCGGTCGCGGCCACCA
AGTTGCGCGATTCGCCGGTGGCCGGCCGCGCGACGGTGCTGATCTTCCCCGATCTCAATACCGGCAACAACACCTACAAA
GCGGTGCAGCGTTCTGCGGGTGCGATCGCGATCGGCCCGGTGCTGCAGGGCTTACGCAAGCCGGTGAACGACCTATCTCG
GGGTGCACTGGTCGACGACATAGTCAACACCGTGGCCATCACGGCGATTCAGGCGCAGGGCGTCCATGAGTAG

Upstream 100 bases:

>100_bases
ACATGGGGCCTGAACCACCTGGTATTTCACGCACCAGGACATGACCAGCGCCGGTTCCTGGAGCTCTTCCAGTCGGACCT
GGCACCCAGGTTGCGGCGAC

Downstream 100 bases:

>100_bases
CACCGTGCTGGTGATCAATTCCGGCTCGTCGTCGCTGAAGTTCCAGCTCGTCGAGCCGGTCGCCGGCATGTCACGTGCCG
CCGGGATTGTCGAGCGGATC

Product: phosphate acetyltransferase

Products: NA

Alternate protein names: Phosphotransacetylase [H]

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MADSSAIYLAAPESQTGKSTIALGLLHRLTAMVAKVGVFRPITRLSAERDYILELLLAHTSAGLPYERCVGVTYQQLHAD
RDDAIAEIVDSYHAMADECDAVVVVGSDYTDVTSPTELSVNARIAVNLGAPVLLTVRAKDRTPDQVASVVEVCLAELDTQ
RAHTAAVVANRCELSAIPAVTDALRRFTPPSYVVPEEPLLSAPTVAELTQAVNGAVVSGDVALREREVMGVLAAGMTADH
VLERLTDGMAVITPGDRSDVVLAVASAHAAEGFPSLSCIVLNGGFQLHPAIAALVSGLRLRLPVIATALGTYDTASAAAS
ARGLVTATSQRKIDTALELMDRHVDVAGLLAQLTIPIPTVTTPQMFTYRLLQQARSDLMRIVLPEGDDDRILKSAGRLLQ
RGIVDLTILGDEAKVRLRAAELGVDLDGATVIEPCASELHDQFADQYAQLRKAKGITVEHAREIMNDATYFGTMLVHNCH
ADGMVSGAAHTTAHTVRPALEIIKTVPGISTVSSIFLMCLPDRVLAYGDCAIIPNPTVEQLADIAICSARTAAQFGIEPR
VAMLSYSTGDSGKGADVDKVRAATELVRAREPQLPVEGPIQYDAAVEPSVAATKLRDSPVAGRATVLIFPDLNTGNNTYK
AVQRSAGAIAIGPVLQGLRKPVNDLSRGALVDDIVNTVAITAIQAQGVHE

Sequences:

>Translated_690_residues
MADSSAIYLAAPESQTGKSTIALGLLHRLTAMVAKVGVFRPITRLSAERDYILELLLAHTSAGLPYERCVGVTYQQLHAD
RDDAIAEIVDSYHAMADECDAVVVVGSDYTDVTSPTELSVNARIAVNLGAPVLLTVRAKDRTPDQVASVVEVCLAELDTQ
RAHTAAVVANRCELSAIPAVTDALRRFTPPSYVVPEEPLLSAPTVAELTQAVNGAVVSGDVALREREVMGVLAAGMTADH
VLERLTDGMAVITPGDRSDVVLAVASAHAAEGFPSLSCIVLNGGFQLHPAIAALVSGLRLRLPVIATALGTYDTASAAAS
ARGLVTATSQRKIDTALELMDRHVDVAGLLAQLTIPIPTVTTPQMFTYRLLQQARSDLMRIVLPEGDDDRILKSAGRLLQ
RGIVDLTILGDEAKVRLRAAELGVDLDGATVIEPCASELHDQFADQYAQLRKAKGITVEHAREIMNDATYFGTMLVHNCH
ADGMVSGAAHTTAHTVRPALEIIKTVPGISTVSSIFLMCLPDRVLAYGDCAIIPNPTVEQLADIAICSARTAAQFGIEPR
VAMLSYSTGDSGKGADVDKVRAATELVRAREPQLPVEGPIQYDAAVEPSVAATKLRDSPVAGRATVLIFPDLNTGNNTYK
AVQRSAGAIAIGPVLQGLRKPVNDLSRGALVDDIVNTVAITAIQAQGVHE
>Mature_689_residues
ADSSAIYLAAPESQTGKSTIALGLLHRLTAMVAKVGVFRPITRLSAERDYILELLLAHTSAGLPYERCVGVTYQQLHADR
DDAIAEIVDSYHAMADECDAVVVVGSDYTDVTSPTELSVNARIAVNLGAPVLLTVRAKDRTPDQVASVVEVCLAELDTQR
AHTAAVVANRCELSAIPAVTDALRRFTPPSYVVPEEPLLSAPTVAELTQAVNGAVVSGDVALREREVMGVLAAGMTADHV
LERLTDGMAVITPGDRSDVVLAVASAHAAEGFPSLSCIVLNGGFQLHPAIAALVSGLRLRLPVIATALGTYDTASAAASA
RGLVTATSQRKIDTALELMDRHVDVAGLLAQLTIPIPTVTTPQMFTYRLLQQARSDLMRIVLPEGDDDRILKSAGRLLQR
GIVDLTILGDEAKVRLRAAELGVDLDGATVIEPCASELHDQFADQYAQLRKAKGITVEHAREIMNDATYFGTMLVHNCHA
DGMVSGAAHTTAHTVRPALEIIKTVPGISTVSSIFLMCLPDRVLAYGDCAIIPNPTVEQLADIAICSARTAAQFGIEPRV
AMLSYSTGDSGKGADVDKVRAATELVRAREPQLPVEGPIQYDAAVEPSVAATKLRDSPVAGRATVLIFPDLNTGNNTYKA
VQRSAGAIAIGPVLQGLRKPVNDLSRGALVDDIVNTVAITAIQAQGVHE

Specific function: Conversion of acetate to acetyl-CoA; second step. [C]

COG id: COG0857

COG function: function code R; BioD-like N-terminal domain of phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788635, Length=721, Percent_Identity=37.7253814147018, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI1788800, Length=312, Percent_Identity=41.3461538461538, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI1788806, Length=336, Percent_Identity=30.952380952381, Blast_Score=164, Evalue=2e-41,

Paralogues:

None

Copy number: 1420 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1250 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010766
- InterPro:   IPR016475
- InterPro:   IPR004614
- InterPro:   IPR002505 [H]

Pfam domain/function: PF07085 DRTGG; PF01515 PTA_PTB [H]

EC number: =2.3.1.8 [H]

Molecular weight: Translated: 72963; Mature: 72832

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADSSAIYLAAPESQTGKSTIALGLLHRLTAMVAKVGVFRPITRLSAERDYILELLLAHT
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SAGLPYERCVGVTYQQLHADRDDAIAEIVDSYHAMADECDAVVVVGSDYTDVTSPTELSV
CCCCCHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEE
NARIAVNLGAPVLLTVRAKDRTPDQVASVVEVCLAELDTQRAHTAAVVANRCELSAIPAV
EEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
TDALRRFTPPSYVVPEEPLLSAPTVAELTQAVNGAVVSGDVALREREVMGVLAAGMTADH
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCHHH
VLERLTDGMAVITPGDRSDVVLAVASAHAAEGFPSLSCIVLNGGFQLHPAIAALVSGLRL
HHHHHHCCEEEECCCCCCCEEEEEECHHHCCCCCCEEEEEEECCCEEHHHHHHHHCCHHH
RLPVIATALGTYDTASAAASARGLVTATSQRKIDTALELMDRHVDVAGLLAQLTIPIPTV
HHHHHHHHHCCCCCHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHEECCCCC
TTPQMFTYRLLQQARSDLMRIVLPEGDDDRILKSAGRLLQRGIVDLTILGDEAKVRLRAA
CCCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEEHH
ELGVDLDGATVIEPCASELHDQFADQYAQLRKAKGITVEHAREIMNDATYFGTMLVHNCH
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
ADGMVSGAAHTTAHTVRPALEIIKTVPGISTVSSIFLMCLPDRVLAYGDCAIIPNPTVEQ
CCCEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHEECCEEECCCCCHHH
LADIAICSARTAAQFGIEPRVAMLSYSTGDSGKGADVDKVRAATELVRAREPQLPVEGPI
HHHHHHHCCHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
QYDAAVEPSVAATKLRDSPVAGRATVLIFPDLNTGNNTYKAVQRSAGAIAIGPVLQGLRK
CCCCCCCCCHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEHHHHHHHHHH
PVNDLSRGALVDDIVNTVAITAIQAQGVHE
HHHHHHCCHHHHHHHHHHHHHHEECCCCCC
>Mature Secondary Structure 
ADSSAIYLAAPESQTGKSTIALGLLHRLTAMVAKVGVFRPITRLSAERDYILELLLAHT
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SAGLPYERCVGVTYQQLHADRDDAIAEIVDSYHAMADECDAVVVVGSDYTDVTSPTELSV
CCCCCHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEE
NARIAVNLGAPVLLTVRAKDRTPDQVASVVEVCLAELDTQRAHTAAVVANRCELSAIPAV
EEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
TDALRRFTPPSYVVPEEPLLSAPTVAELTQAVNGAVVSGDVALREREVMGVLAAGMTADH
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCHHH
VLERLTDGMAVITPGDRSDVVLAVASAHAAEGFPSLSCIVLNGGFQLHPAIAALVSGLRL
HHHHHHCCEEEECCCCCCCEEEEEECHHHCCCCCCEEEEEEECCCEEHHHHHHHHCCHHH
RLPVIATALGTYDTASAAASARGLVTATSQRKIDTALELMDRHVDVAGLLAQLTIPIPTV
HHHHHHHHHCCCCCHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHEECCCCC
TTPQMFTYRLLQQARSDLMRIVLPEGDDDRILKSAGRLLQRGIVDLTILGDEAKVRLRAA
CCCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEEHH
ELGVDLDGATVIEPCASELHDQFADQYAQLRKAKGITVEHAREIMNDATYFGTMLVHNCH
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
ADGMVSGAAHTTAHTVRPALEIIKTVPGISTVSSIFLMCLPDRVLAYGDCAIIPNPTVEQ
CCCEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHEECCEEECCCCCHHH
LADIAICSARTAAQFGIEPRVAMLSYSTGDSGKGADVDKVRAATELVRAREPQLPVEGPI
HHHHHHHCCHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
QYDAAVEPSVAATKLRDSPVAGRATVLIFPDLNTGNNTYKAVQRSAGAIAIGPVLQGLRK
CCCCCCCCCHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEHHHHHHHHHH
PVNDLSRGALVDDIVNTVAITAIQAQGVHE
HHHHHHCCHHHHHHHHHHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]