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The map label for this gene is fadE3 [H]

Identifier: 121636127

GI number: 121636127

Start: 287622

End: 288788

Strand: Reverse

Name: fadE3 [H]

Synonym: BCG_0252c

Alternate gene names: 121636127

Gene position: 288788-287622 (Counterclockwise)

Preceding gene: 121636129

Following gene: 121636125

Centisome position: 6.6

GC content: 64.7

Gene sequence:

>1167_bases
GTGCGCAACGAGCTCAACGACGACGAAGCGATGCTGGTCGCCACCGTGCGGGCATTCATCGACCGAGACGTGAAGCCAAC
CGTCCGTGAGGTCGAGCATGCCAATAGCTACCCGGAGGCGTGGATCGAGCAGATGAAACACATCGGCATCTACGGCCTGG
CGATCGACGAACAGTACGGCGGGTCGCCGGTGTCGATGCCGTGCTATGTGCAAGTCACCCAGGAGCTGGCACGCGGCTGG
ATGAGCCTGGCCGGCGCGATGGGCGGGCACACCGTCGTCGCCAAATTGCTGACCCTGTTTGGCACCGAGGAACAGCGGCG
GACATATCTGCCCCCGATGGCCAGTGGCGAGCTGCGGGCCACCATGGCGCTAACCGAGCCCGGCGGTGGCTCGGATCTGC
AGAACATGTCGACCACGGCGTTGGCCGACGGCCCTGAAGGCTCTGCCGGGTTGTTGATCAACGGCTGCAAGACGTGGATC
AGCAACGCCCGCCGGTCCGGACTTTTCGCGGTGCTGTGCAAGACCGACCCGAACGCCACACCGCGGCACCAAGGCATGTC
GATCGTGCTCGTCGAACCCGGGCCGGGACTCACGGTGTCGCGGGACTTGCCGAAGTTGGGTTACAAGGGCGTCGAATCCT
GCGAGCTGTCGTTCGACAACCTCCGGGTGCCGGTCTCGGCGATCCTGGGCGGAGCCATGGGTCAAGGCTTTTCGCAGATG
ATGAAGGGCCTTGAAACGGGTCGCATCCAAGTGGCCGCGCGGGCGCTGGGCGTGGCGACGGCGGCACTCGAGGACTCGCT
GGCCTACGCTCAGCAACGGGAAAGCTTTGGCCGACCGATCTGGCAGCATCAGGCGGTCGGCAATTACCTGGCCGACATGG
CGACCAAGCTCACAGCGGCCCGTCAGCTGACCCGCTATGCCGCCGAGCGGTACGACAGCGGCCAACGCTGCGATATGGAG
GCCGGGATGGCCAAGTTGTTCGCCTCCGAGGTCGCGATGGAAATCGCCCTAAACGCCGTGCGTATCCACGGCGGCTACGG
CTACTCGACCGAGTACGACGTGGAACGGTACTTCCGCGACTCACCCTTGATGATCCTCGGTGAAGGCACCAACGAGATCC
AGCGCAACGTGATAGCCGGACAACTGGTGGCCCGGGGCGGGATATAG

Upstream 100 bases:

>100_bases
AAATAGGGCCCGCCGACGCGGATGCCCCCATACCCGCTAGCCACAACGCCACATTCTGGCAGGCTATCGGACAGGGGGTC
AATACGGAGGGCGACAAAAG

Downstream 100 bases:

>100_bases
CCGGTGTCTGGGTGGACAGGTCGGGCCCCCGGCAGCATCGGTCACACCGAGTATTTTTCGACCAGCCCGCTCTTGTAGAG
CTTTCCGGTGTCGGTGCGCG

Product: putative acyl-CoA dehydrogenase fadE3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRNELNDDEAMLVATVRAFIDRDVKPTVREVEHANSYPEAWIEQMKHIGIYGLAIDEQYGGSPVSMPCYVQVTQELARGW
MSLAGAMGGHTVVAKLLTLFGTEEQRRTYLPPMASGELRATMALTEPGGGSDLQNMSTTALADGPEGSAGLLINGCKTWI
SNARRSGLFAVLCKTDPNATPRHQGMSIVLVEPGPGLTVSRDLPKLGYKGVESCELSFDNLRVPVSAILGGAMGQGFSQM
MKGLETGRIQVAARALGVATAALEDSLAYAQQRESFGRPIWQHQAVGNYLADMATKLTAARQLTRYAAERYDSGQRCDME
AGMAKLFASEVAMEIALNAVRIHGGYGYSTEYDVERYFRDSPLMILGEGTNEIQRNVIAGQLVARGGI

Sequences:

>Translated_388_residues
MRNELNDDEAMLVATVRAFIDRDVKPTVREVEHANSYPEAWIEQMKHIGIYGLAIDEQYGGSPVSMPCYVQVTQELARGW
MSLAGAMGGHTVVAKLLTLFGTEEQRRTYLPPMASGELRATMALTEPGGGSDLQNMSTTALADGPEGSAGLLINGCKTWI
SNARRSGLFAVLCKTDPNATPRHQGMSIVLVEPGPGLTVSRDLPKLGYKGVESCELSFDNLRVPVSAILGGAMGQGFSQM
MKGLETGRIQVAARALGVATAALEDSLAYAQQRESFGRPIWQHQAVGNYLADMATKLTAARQLTRYAAERYDSGQRCDME
AGMAKLFASEVAMEIALNAVRIHGGYGYSTEYDVERYFRDSPLMILGEGTNEIQRNVIAGQLVARGGI
>Mature_388_residues
MRNELNDDEAMLVATVRAFIDRDVKPTVREVEHANSYPEAWIEQMKHIGIYGLAIDEQYGGSPVSMPCYVQVTQELARGW
MSLAGAMGGHTVVAKLLTLFGTEEQRRTYLPPMASGELRATMALTEPGGGSDLQNMSTTALADGPEGSAGLLINGCKTWI
SNARRSGLFAVLCKTDPNATPRHQGMSIVLVEPGPGLTVSRDLPKLGYKGVESCELSFDNLRVPVSAILGGAMGQGFSQM
MKGLETGRIQVAARALGVATAALEDSLAYAQQRESFGRPIWQHQAVGNYLADMATKLTAARQLTRYAAERYDSGQRCDME
AGMAKLFASEVAMEIALNAVRIHGGYGYSTEYDVERYFRDSPLMILGEGTNEIQRNVIAGQLVARGGI

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=382, Percent_Identity=37.434554973822, Blast_Score=235, Evalue=5e-62,
Organism=Homo sapiens, GI4501859, Length=383, Percent_Identity=34.2036553524804, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI226958412, Length=381, Percent_Identity=32.2834645669291, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI7656849, Length=385, Percent_Identity=33.7662337662338, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI187960098, Length=384, Percent_Identity=31.5104166666667, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI4557231, Length=384, Percent_Identity=31.5104166666667, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI226958414, Length=342, Percent_Identity=33.6257309941521, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI4501857, Length=389, Percent_Identity=32.133676092545, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI21361497, Length=384, Percent_Identity=31.5104166666667, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI76496475, Length=378, Percent_Identity=30.4232804232804, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4557235, Length=378, Percent_Identity=30.4232804232804, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4503943, Length=381, Percent_Identity=28.6089238845144, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI7669494, Length=364, Percent_Identity=28.8461538461538, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI38505218, Length=393, Percent_Identity=25.9541984732824, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI48976061, Length=296, Percent_Identity=30.0675675675676, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI211971008, Length=296, Percent_Identity=30.0675675675676, Blast_Score=110, Evalue=3e-24,
Organism=Escherichia coli, GI87081958, Length=391, Percent_Identity=31.7135549872123, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1786223, Length=383, Percent_Identity=28.7206266318538, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI87081702, Length=403, Percent_Identity=24.5657568238213, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082384, Length=268, Percent_Identity=27.2388059701493, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17506239, Length=379, Percent_Identity=35.3562005277045, Blast_Score=219, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17570075, Length=387, Percent_Identity=35.1421188630491, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17508101, Length=379, Percent_Identity=35.3562005277045, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI17534899, Length=384, Percent_Identity=34.375, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=33.245382585752, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17569725, Length=360, Percent_Identity=33.3333333333333, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17533517, Length=383, Percent_Identity=28.4595300261097, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI71990804, Length=283, Percent_Identity=36.0424028268551, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI71985184, Length=364, Percent_Identity=28.8461538461538, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI32563615, Length=237, Percent_Identity=35.4430379746835, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17505929, Length=386, Percent_Identity=28.2383419689119, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17551932, Length=366, Percent_Identity=27.5956284153005, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17534353, Length=389, Percent_Identity=25.9640102827763, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71985192, Length=311, Percent_Identity=27.3311897106109, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=30.5454545454545, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17562446, Length=391, Percent_Identity=25.5754475703325, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17531909, Length=245, Percent_Identity=28.1632653061224, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646207, Length=380, Percent_Identity=35.7894736842105, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI21356377, Length=381, Percent_Identity=35.6955380577428, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=34.3007915567282, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI21355753, Length=382, Percent_Identity=31.413612565445, Blast_Score=193, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24660351, Length=377, Percent_Identity=32.6259946949602, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI281363737, Length=340, Percent_Identity=29.1176470588235, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI19920834, Length=375, Percent_Identity=26.6666666666667, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41964; Mature: 41964

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNELNDDEAMLVATVRAFIDRDVKPTVREVEHANSYPEAWIEQMKHIGIYGLAIDEQYG
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCEEEEEEECCCC
GSPVSMPCYVQVTQELARGWMSLAGAMGGHTVVAKLLTLFGTEEQRRTYLPPMASGELRA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEE
TMALTEPGGGSDLQNMSTTALADGPEGSAGLLINGCKTWISNARRSGLFAVLCKTDPNAT
EEEEECCCCCCCHHHCCHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCEEEEEEECCCCCC
PRHQGMSIVLVEPGPGLTVSRDLPKLGYKGVESCELSFDNLRVPVSAILGGAMGQGFSQM
CCCCCCEEEEECCCCCCEECCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHCCCHHHH
MKGLETGRIQVAARALGVATAALEDSLAYAQQRESFGRPIWQHQAVGNYLADMATKLTAA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RQLTRYAAERYDSGQRCDMEAGMAKLFASEVAMEIALNAVRIHGGYGYSTEYDVERYFRD
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHCC
SPLMILGEGTNEIQRNVIAGQLVARGGI
CCEEEEECCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRNELNDDEAMLVATVRAFIDRDVKPTVREVEHANSYPEAWIEQMKHIGIYGLAIDEQYG
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCEEEEEEECCCC
GSPVSMPCYVQVTQELARGWMSLAGAMGGHTVVAKLLTLFGTEEQRRTYLPPMASGELRA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEE
TMALTEPGGGSDLQNMSTTALADGPEGSAGLLINGCKTWISNARRSGLFAVLCKTDPNAT
EEEEECCCCCCCHHHCCHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCEEEEEEECCCCCC
PRHQGMSIVLVEPGPGLTVSRDLPKLGYKGVESCELSFDNLRVPVSAILGGAMGQGFSQM
CCCCCCEEEEECCCCCCEECCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHCCCHHHH
MKGLETGRIQVAARALGVATAALEDSLAYAQQRESFGRPIWQHQAVGNYLADMATKLTAA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RQLTRYAAERYDSGQRCDMEAGMAKLFASEVAMEIALNAVRIHGGYGYSTEYDVERYFRD
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHCC
SPLMILGEGTNEIQRNVIAGQLVARGGI
CCEEEEECCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]