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The map label for this gene is bioC [C]

Identifier: 121636002

GI number: 121636002

Start: 127499

End: 128092

Strand: Direct

Name: bioC [C]

Synonym: BCG_0122

Alternate gene names: 121636002

Gene position: 127499-128092 (Clockwise)

Preceding gene: 121636001

Following gene: 121636003

Centisome position: 2.91

GC content: 67.0

Gene sequence:

>594_bases
GTGGATCAACCGTGGAACGCCAACATCCACTACGACGCTCTGCTGGATGCCATGGTGCCGCTCGGTACCCAGTGCGTGCT
CGACGTCGGGTGCGGCGACGGGTTGCTGGCTGCCCGGCTGGCTCGGCGCATACCCTACGTCACGGCAGTGGACATCGATG
CGCCCGTCCTGCGACGTGCGCAGACACGGTTCGCCAACGCGCCGATCCGCTGGCTGCATGCCGACATCATGACGGCTGAG
CTGCCCAACGCGGGCTTCGACGCCGTGGTCTCCAATGCCGCCCTGCACCACATCGAGGACACTCGGACGGCGCTGAGCCG
GCTCGGCGGGCTGGTAACTCCCGGTGGGACGCTGGCCGTGGTCACCTTCGTGACGCCCTCGCTGCGAAACGGCTTATGGC
ACTTGACAAGCTGGGTTGCCTGCGGCATGGCCAATCGCGTCAAGGGCAAGTGGGAACATTCCGCTCCGATCAAGTGGCCG
CCCCCGCAGACGTTGCATGAGCTACGCAGCCACGTTCGCGCCCTGCTGCCCGGGGCGTGTATCCGTCGGCTGCTGTACGG
CCGGGTGCTCGTTACGTGGCGCGCACCCGTCTAA

Upstream 100 bases:

>100_bases
AGAAAAGATGTACCAGATCACCTGCCTGAATAGGATTTCTGGCCCGACGTAGCTTCGGGCTAGCGCGAGCGACGACTCCG
CCGTCGAGCAGGATGTCACC

Downstream 100 bases:

>100_bases
TCGGGAGAACCCAATGGCGGCGGCCGATATGACCAAGTGCGCGTTAGCTTGCGAGATTGGCTGCCCGCATCCAATGATCG
GCGGATACGGGTCGCAAACC

Product: putative methyltransferase/methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRFANAPIRWLHADIMTAE
LPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTFVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWP
PPQTLHELRSHVRALLPGACIRRLLYGRVLVTWRAPV

Sequences:

>Translated_197_residues
MDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRFANAPIRWLHADIMTAE
LPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTFVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWP
PPQTLHELRSHVRALLPGACIRRLLYGRVLVTWRAPV
>Mature_197_residues
MDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRFANAPIRWLHADIMTAE
LPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTFVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWP
PPQTLHELRSHVRALLPGACIRRLLYGRVLVTWRAPV

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y089_MYCTU (P65346)

Other databases:

- EMBL:   BX842572
- EMBL:   AE000516
- PIR:   A70750
- RefSeq:   NP_214603.1
- RefSeq:   NP_334506.1
- ProteinModelPortal:   P65346
- SMR:   P65346
- EnsemblBacteria:   EBMYCT00000002295
- EnsemblBacteria:   EBMYCT00000069897
- GeneID:   886949
- GeneID:   922900
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0098
- KEGG:   mtu:Rv0089
- TIGR:   MT0098
- TubercuList:   Rv0089
- GeneTree:   EBGT00050000014599
- HOGENOM:   HBG570206
- OMA:   YHRWILR
- ProtClustDB:   CLSK790254
- InterPro:   IPR013216

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 21596; Mature: 21596

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRA
CCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCHHHHHHH
QTRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAV
HHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
VTFVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGAC
EEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHH
IRRLLYGRVLVTWRAPV
HHHHHHHHEEEEEECCC
>Mature Secondary Structure
MDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRA
CCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCHHHHHHH
QTRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAV
HHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
VTFVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGAC
EEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHH
IRRLLYGRVLVTWRAPV
HHHHHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036