| Definition | Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome. |
|---|---|
| Accession | NC_008769 |
| Length | 4,374,522 |
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The map label for this gene is pstP [H]
Identifier: 121635928
GI number: 121635928
Start: 51303
End: 52847
Strand: Reverse
Name: pstP [H]
Synonym: BCG_0048c
Alternate gene names: 121635928
Gene position: 52847-51303 (Counterclockwise)
Preceding gene: 121635929
Following gene: 121635927
Centisome position: 1.21
GC content: 67.57
Gene sequence:
>1545_bases GTGGCGCTCGTGACCCTGGTCCTGCGATACGCGGCGCGCAGCGATCGCGGCTTGGTACGCGCCAACAACGAAGACTCGGT CTACGCTGGGGCACGGCTATTGGCCCTGGCCGACGGCATGGGTGGGCATGCGGCCGGCGAGGTGGCGTCCCAGTTGGTGA TTGCCGCATTGGCCCATCTCGATGACGACGAGCCCGGTGGCGATCTGCTGGCCAAGCTGGATGCCGCGGTGCGCGCCGGC AACTCGGCTATCGCAGCGCAAGTCGAGATGGAGCCCGATCTCGAAGGCATGGGTACCACGCTCACCGCAATCCTGTTCGC GGGCAACCGGCTCGGCCTGGTGCATATCGGTGACTCGCGCGGTTACCTGCTGCGCGACGGTGAGCTGACGCAGATCACCA AGGACGACACGTTTGTCCAAACGCTGGTCGACGAAGGCCGGATCACCCCGGAGGAGGCGCACAGCCACCCGCAACGCTCG TTGATCATGCGGGCGTTGACCGGCCATGAGGTCGAACCGACGCTGACCATGCGAGAAGCCCGCGCCGGTGATCGTTACCT GCTGTGCTCGGACGGGTTGTCCGATCCGGTTAGCGATGAAACTATCCTCGAGGCCCTGCAGATCCCCGAGGTTGCCGAGA GCGCTCACCGCCTCATTGAACTGGCGCTGCGCGGCGGCGGCCCCGACAACGTCACTGTCGTCGTCGCCGACGTCGTCGAC TACGACTACGGCCAGACCCAACCGATTCTGGCCGGGGCGGTCTCAGGCGACGACGACCAACTGACCCTGCCCAACACCGC CGCCGGCCGGGCCTCTGCCATCAGCCAGCGCAAGGAGATCGTTAAACGCGTTCCGCCACAGGCCGATACATTCAGTCGGC CACGGTGGTCGGGCCGACGGCTAGCATTCGTTGTCGCCCTGGTGACCGTGCTGATGACTGCGGGCCTGCTCATTGGTCGC GCGATCATCCGCAGCAACTACTACGTAGCGGACTACGCCGGCAGCGTGTCCATCATGCGGGGGATTCAAGGGTCGCTACT GGGCATGTCCCTGCACCAGCCTTACCTGATGGGCTGCCTCAGCCCGCGTAACGAGCTGTCGCAGATCAGCTACGGACAGT CTGGGGGCCCTCTCGACTGCCATCTGATGAAACTGGAGGATCTGCGACCGCCGGAGCGCGCACAGGTTCGGGCCGGTCTC CCGGCCGGCACTCTCGATGACGCCATCGGGCAGTTGCGCGAACTGGCGGCCAACTCCCTGCTGCCGCCTTGCCCGGCGCC GCGTGCCACGTCCCCGCCCGGGCGCCCGGCCCCACCCACCACCAGCGAGACAACCGAACCAAACGTCACCTCCTCGCCAG CCGCTCCATCACCCACCACCTCCGCGTCGGCCCCCACCGGAACTACTCCTGCCATCCCCACGAGTGCCTCCCCGGCAGCG CCCGCGTCGCCGCCGACGCCTTGGCCCGTCACCAGCTCGCCGACGATGGCCGCACTTCCGCCACCCCCGCCTCAGCCGGG CATCGACTGCCGGGCGGCGGCATGA
Upstream 100 bases:
>100_bases TTGCGCCCGTGACCCGCGCTGGCGACGATGCAGAGCGCAGAGAAGCGGTGGGGGCGCGCCCCCACAAGTGGGGGGTACCC CCACCCGCTTGCGGGGGAGA
Downstream 100 bases:
>100_bases CGACACGACTGCAAGCGCCGGTGGCCGTAACGCCCCCGTTGCCGACTCGGCGCAACGCTGAACTGCTGCTGCTGTGCTTT GCCGCCGTAATCACGTTTGC
Product: Serine/threonine phosphatase PPP
Products: NA
Alternate protein names: Mycobacterial Ser/Thr phosphatase; Mstp; Possible serine/threonine phosphatase Ppp [H]
Number of amino acids: Translated: 514; Mature: 513
Protein sequence:
>514_residues MALVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPGGDLLAKLDAAVRAG NSAIAAQVEMEPDLEGMGTTLTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITPEEAHSHPQRS LIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDETILEALQIPEVAESAHRLIELALRGGGPDNVTVVVADVVD YDYGQTQPILAGAVSGDDDQLTLPNTAAGRASAISQRKEIVKRVPPQADTFSRPRWSGRRLAFVVALVTVLMTAGLLIGR AIIRSNYYVADYAGSVSIMRGIQGSLLGMSLHQPYLMGCLSPRNELSQISYGQSGGPLDCHLMKLEDLRPPERAQVRAGL PAGTLDDAIGQLRELAANSLLPPCPAPRATSPPGRPAPPTTSETTEPNVTSSPAAPSPTTSASAPTGTTPAIPTSASPAA PASPPTPWPVTSSPTMAALPPPPPQPGIDCRAAA
Sequences:
>Translated_514_residues MALVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPGGDLLAKLDAAVRAG NSAIAAQVEMEPDLEGMGTTLTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITPEEAHSHPQRS LIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDETILEALQIPEVAESAHRLIELALRGGGPDNVTVVVADVVD YDYGQTQPILAGAVSGDDDQLTLPNTAAGRASAISQRKEIVKRVPPQADTFSRPRWSGRRLAFVVALVTVLMTAGLLIGR AIIRSNYYVADYAGSVSIMRGIQGSLLGMSLHQPYLMGCLSPRNELSQISYGQSGGPLDCHLMKLEDLRPPERAQVRAGL PAGTLDDAIGQLRELAANSLLPPCPAPRATSPPGRPAPPTTSETTEPNVTSSPAAPSPTTSASAPTGTTPAIPTSASPAA PASPPTPWPVTSSPTMAALPPPPPQPGIDCRAAA >Mature_513_residues ALVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPGGDLLAKLDAAVRAGN SAIAAQVEMEPDLEGMGTTLTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITPEEAHSHPQRSL IMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDETILEALQIPEVAESAHRLIELALRGGGPDNVTVVVADVVDY DYGQTQPILAGAVSGDDDQLTLPNTAAGRASAISQRKEIVKRVPPQADTFSRPRWSGRRLAFVVALVTVLMTAGLLIGRA IIRSNYYVADYAGSVSIMRGIQGSLLGMSLHQPYLMGCLSPRNELSQISYGQSGGPLDCHLMKLEDLRPPERAQVRAGLP AGTLDDAIGQLRELAANSLLPPCPAPRATSPPGRPAPPTTSETTEPNVTSSPAAPSPTTSASAPTGTTPAIPTSASPAAP ASPPTPWPVTSSPTMAALPPPPPQPGIDCRAAA
Specific function: The only predicted protein phosphatase in M.tuberculosis, it dephosphorylates at least 5 protein kinases (pknA, pknB, pknD, pknE and pknF) and the penicillin-binding protein PBPA [H]
COG id: COG0631
COG function: function code T; Serine/threonine protein phosphatase
Gene ontology:
Cell location: Cell membrane; Single-pass membrane protein (Potential). Note=May be localized to the outside of the cell [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PP2C-like domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015655 - InterPro: IPR001932 - InterPro: IPR014045 [H]
Pfam domain/function: PF00481 PP2C [H]
EC number: =3.1.3.16 [H]
Molecular weight: Translated: 53743; Mature: 53612
Theoretical pI: Translated: 4.78; Mature: 4.78
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MALVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHL CHHHHHHHHHHHCCCCCEEEECCCCCHHHCEEEEEEECCCCCCHHHHHHHHHHHHHHHHC DDDEPGGDLLAKLDAAVRAGNSAIAAQVEMEPDLEGMGTTLTAILFAGNRLGLVHIGDSR CCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCC GYLLRDGELTQITKDDTFVQTLVDEGRITPEEAHSHPQRSLIMRALTGHEVEPTLTMREA CEEEECCCEEEECCCHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCEEHHHH RAGDRYLLCSDGLSDPVSDETILEALQIPEVAESAHRLIELALRGGGPDNVTVVVADVVD CCCCCEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECC YDYGQTQPILAGAVSGDDDQLTLPNTAAGRASAISQRKEIVKRVPPQADTFSRPRWSGRR CCCCCCCCEEEEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH LAFVVALVTVLMTAGLLIGRAIIRSNYYVADYAGSVSIMRGIQGSLLGMSLHQPYLMGCL HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHCCCHHHCCHHHCCHHHHHHC SPRNELSQISYGQSGGPLDCHLMKLEDLRPPERAQVRAGLPAGTLDDAIGQLRELAANSL CCHHHHHHHCCCCCCCCCEEEEEEHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCC LPPCPAPRATSPPGRPAPPTTSETTEPNVTSSPAAPSPTTSASAPTGTTPAIPTSASPAA CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC PASPPTPWPVTSSPTMAALPPPPPQPGIDCRAAA CCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC >Mature Secondary Structure ALVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHL HHHHHHHHHHHCCCCCEEEECCCCCHHHCEEEEEEECCCCCCHHHHHHHHHHHHHHHHC DDDEPGGDLLAKLDAAVRAGNSAIAAQVEMEPDLEGMGTTLTAILFAGNRLGLVHIGDSR CCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCC GYLLRDGELTQITKDDTFVQTLVDEGRITPEEAHSHPQRSLIMRALTGHEVEPTLTMREA CEEEECCCEEEECCCHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCEEHHHH RAGDRYLLCSDGLSDPVSDETILEALQIPEVAESAHRLIELALRGGGPDNVTVVVADVVD CCCCCEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECC YDYGQTQPILAGAVSGDDDQLTLPNTAAGRASAISQRKEIVKRVPPQADTFSRPRWSGRR CCCCCCCCEEEEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH LAFVVALVTVLMTAGLLIGRAIIRSNYYVADYAGSVSIMRGIQGSLLGMSLHQPYLMGCL HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHCCCHHHCCHHHCCHHHHHHC SPRNELSQISYGQSGGPLDCHLMKLEDLRPPERAQVRAGLPAGTLDDAIGQLRELAANSL CCHHHHHHHCCCCCCCCCEEEEEEHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCC LPPCPAPRATSPPGRPAPPTTSETTEPNVTSSPAAPSPTTSASAPTGTTPAIPTSASPAA CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC PASPPTPWPVTSSPTMAALPPPPPQPGIDCRAAA CCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]