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The map label for this gene is panE [C]

Identifier: 120613365

GI number: 120613365

Start: 5284705

End: 5285697

Strand: Direct

Name: panE [C]

Synonym: Aave_4737

Alternate gene names: 120613365

Gene position: 5284705-5285697 (Clockwise)

Preceding gene: 120613358

Following gene: 120613369

Centisome position: 98.73

GC content: 74.82

Gene sequence:

>993_bases
ATGCATTTCATCGTCATGGGCGCGGGCGCCATCGGCCTCCATGTGGGCGGACGCCTGGCCGCGGCCGGGGAGGCGGTGAC
CCTGGTGGGCCGCCCCCGCATCCTGGATGCGATCGCACGGGACGGCCTGCGGGTGAGCGACCTGGAGGGAGCCGATGCGC
ACGTGCCCGCGCACGCGCTGCGGCTGGCCCCGTCGCTGGACGGCATGGAATGCCCCGGCGACGCCATCGTCCTGCTGTGC
GTGAAAGGCGGCGCCACGGCGCAGGCCGCGCGCGCCCTGGGCGCCGCCTGCCCGCCGGGCACGCCCGTGGTGTCGCTGCA
GAACGGCGTGGACAACGTGGCGCGCATCGCCGCCCATGCGCCAGCGCTGCGGCCCATCGGGGCCATGGTGCCCTACAACG
TGGTGCTGCGCGGCACGCATGTGCACCGCGCGACCGCCGGATGCATCCACCTGCAGCGCGACCCGGCCGCCGACGCGGTG
GCCGAAGCCTTCAGGGCGGCGGGACTGGGCACCACGGTCGTGGAGGACATTCGCCCGGTGCAGTGGGGCAAGCTGCTCCT
GAACCTCAACAACCCCGTGAATGCACTCTCGGACCTGCCGCTGCGCGAGGAACTGCAGGACCGCGACTGCCGCGCCGTGT
TCGCCGCGCTGCAGGCCGAAGCGCTGCGCGCCATGGCGCGCGCCGGCGTCCGCCCCGCGAAGGTCACGCCCGTGCCGCCG
GCACTGCTGCCGCACGTGCTGCGGCTGCCCGACGCGCTTTTCACCCGGCTCGCGCGCCGCATGCTGCGCATCGATCCGGC
GGCTCGCTCCTCGATGTGGGACGACCTGGAGGCCGGCCGCCCCACCGAGATCGACGACCTCTGCGGCGCCGTCGTGCGCC
TGGCCGCGGCGCATGGCCTGCGCGCGCCCTGCAACGAACGCATGTGCGCGCTACTGGCCGGCCCGCGCCAGCGGCTCACG
GGTGCGCAGATGCGCGAGGCCCTGGGGCTCTGA

Upstream 100 bases:

>100_bases
TGCGGGATGCGCGCCGCCGCTCCCTGCCGCCACCGGCCGCACAATCCGCCCACACCGTCACGGGCGCCGGGCCCCTGCAC
GGCCCTTCGGGAGGCTTCGC

Downstream 100 bases:

>100_bases
TGCAGACCGCGCCTGGCACGTCCCGCTCCAGCCAGGGCCTGCGCCATGCGGCACCGCTCACCCCCCGTGGATCGCCGCCG
CCACGATGATGCTGATGCCC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MHFIVMGAGAIGLHVGGRLAAAGEAVTLVGRPRILDAIARDGLRVSDLEGADAHVPAHALRLAPSLDGMECPGDAIVLLC
VKGGATAQAARALGAACPPGTPVVSLQNGVDNVARIAAHAPALRPIGAMVPYNVVLRGTHVHRATAGCIHLQRDPAADAV
AEAFRAAGLGTTVVEDIRPVQWGKLLLNLNNPVNALSDLPLREELQDRDCRAVFAALQAEALRAMARAGVRPAKVTPVPP
ALLPHVLRLPDALFTRLARRMLRIDPAARSSMWDDLEAGRPTEIDDLCGAVVRLAAAHGLRAPCNERMCALLAGPRQRLT
GAQMREALGL

Sequences:

>Translated_330_residues
MHFIVMGAGAIGLHVGGRLAAAGEAVTLVGRPRILDAIARDGLRVSDLEGADAHVPAHALRLAPSLDGMECPGDAIVLLC
VKGGATAQAARALGAACPPGTPVVSLQNGVDNVARIAAHAPALRPIGAMVPYNVVLRGTHVHRATAGCIHLQRDPAADAV
AEAFRAAGLGTTVVEDIRPVQWGKLLLNLNNPVNALSDLPLREELQDRDCRAVFAALQAEALRAMARAGVRPAKVTPVPP
ALLPHVLRLPDALFTRLARRMLRIDPAARSSMWDDLEAGRPTEIDDLCGAVVRLAAAHGLRAPCNERMCALLAGPRQRLT
GAQMREALGL
>Mature_330_residues
MHFIVMGAGAIGLHVGGRLAAAGEAVTLVGRPRILDAIARDGLRVSDLEGADAHVPAHALRLAPSLDGMECPGDAIVLLC
VKGGATAQAARALGAACPPGTPVVSLQNGVDNVARIAAHAPALRPIGAMVPYNVVLRGTHVHRATAGCIHLQRDPAADAV
AEAFRAAGLGTTVVEDIRPVQWGKLLLNLNNPVNALSDLPLREELQDRDCRAVFAALQAEALRAMARAGVRPAKVTPVPP
ALLPHVLRLPDALFTRLARRMLRIDPAARSSMWDDLEAGRPTEIDDLCGAVVRLAAAHGLRAPCNERMCALLAGPRQRLT
GAQMREALGL

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 34575; Mature: 34575

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFIVMGAGAIGLHVGGRLAAAGEAVTLVGRPRILDAIARDGLRVSDLEGADAHVPAHAL
CEEEEEECCEEEEECCCEEEECCCEEEEECCCHHHHHHHHCCCEEECCCCCCCCCCHHHH
RLAPSLDGMECPGDAIVLLCVKGGATAQAARALGAACPPGTPVVSLQNGVDNVARIAAHA
HHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHC
PALRPIGAMVPYNVVLRGTHVHRATAGCIHLQRDPAADAVAEAFRAAGLGTTVVEDIRPV
CCCCHHHHHCCCEEEEECCHHHHHHHCEEEECCCCHHHHHHHHHHHCCCCHHHHHHCCCC
QWGKLLLNLNNPVNALSDLPLREELQDRDCRAVFAALQAEALRAMARAGVRPAKVTPVPP
CCCEEEEECCCCHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
ALLPHVLRLPDALFTRLARRMLRIDPAARSSMWDDLEAGRPTEIDDLCGAVVRLAAAHGL
HHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
RAPCNERMCALLAGPRQRLTGAQMREALGL
CCCHHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHFIVMGAGAIGLHVGGRLAAAGEAVTLVGRPRILDAIARDGLRVSDLEGADAHVPAHAL
CEEEEEECCEEEEECCCEEEECCCEEEEECCCHHHHHHHHCCCEEECCCCCCCCCCHHHH
RLAPSLDGMECPGDAIVLLCVKGGATAQAARALGAACPPGTPVVSLQNGVDNVARIAAHA
HHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHC
PALRPIGAMVPYNVVLRGTHVHRATAGCIHLQRDPAADAVAEAFRAAGLGTTVVEDIRPV
CCCCHHHHHCCCEEEEECCHHHHHHHCEEEECCCCHHHHHHHHHHHCCCCHHHHHHCCCC
QWGKLLLNLNNPVNALSDLPLREELQDRDCRAVFAALQAEALRAMARAGVRPAKVTPVPP
CCCEEEEECCCCHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
ALLPHVLRLPDALFTRLARRMLRIDPAARSSMWDDLEAGRPTEIDDLCGAVVRLAAAHGL
HHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
RAPCNERMCALLAGPRQRLTGAQMREALGL
CCCHHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]