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The map label for this gene is dhbF [H]

Identifier: 120613289

GI number: 120613289

Start: 5193956

End: 5198305

Strand: Direct

Name: dhbF [H]

Synonym: Aave_4658

Alternate gene names: 120613289

Gene position: 5193956-5198305 (Clockwise)

Preceding gene: 120613288

Following gene: 120613290

Centisome position: 97.03

GC content: 69.33

Gene sequence:

>4350_bases
ATGCGCGCCAGCCATTTCCCCGTCCAGACCCTTCCATTGACCGCGGCCCAGATGGGCATGTGGTTCGGTACACGCTTCGC
GTCGCCCGAGGCCAACTTCAATCTCGCGGAGGCCATCGAGATCTACGGGAGCTTCGAGCCCCGGTTGCTGCTGCAGGCCT
TGCGCACCCTGTGCGCAGAAGCCGATTCCATCCGCCTGCGTGTCGCGGACACGCCCCAGGGCCCGCGGCAGTGGCTCGAA
GCAGAGTTCTCGGGCAGCATCTCGATGCTCGATTTCAGCGGCGACGGCGATCCCCGGGCCTCGGCCGAGCAATGGATGGC
CGACGAATCCTCCCGCCGCATGGACGTCGAGCGGGAGCCCATGTGGTCCAGCGCGGTGCTCCGCATCGCTCCGGACCACC
ACATCTGGTATCAGCGCGGACACCACTACGCCTTCGACGGCTTCGCCGCCGTCGTTCTCGCGCGCCGGGCGGCAGACCTG
TACACGGCGCTGGTGAACGGCACGGCTGCGCCCGCGGATTCGGAACTGAAACCGCTGTCCGTCCTGATCGAGGAGGACCA
GGCCTATCGCGACTCCGCGCGTGCCCTGAAAGACCGCGAATACTGGATGGAGCGGATGCGTGACCGCCCCGAGCCGCTGA
CCCTCGCCGAACGGCGCAGCAACAACATCGGCGGACTGCTGCGGCACACGGCACACTGGCCGGCGGCGCGCGTCGCCGCG
CTGCGCGATACGGCCGCACTGCACGGCGGCACGCTGCCGCAGATCCTGATCGCGGCGACGGCCACCTATCTGTACCGGAT
GACAGGGGTTTCCGACCTGGTGATCGGCGTTCCCGTGACGGCGCGCTACAACGACCGCATGCGGCGCGTACCGGGCATGG
TCGCCAACGCGGTGCCCCTGCGCCTGTCCATGCGGCCCGAAATGCCCTTCACGGCCCTGCTGCGCGAGGTCAGCCAGCAG
ATGCGCAAGATCCTGCGCCACCAGGCCTACCGTTACGAGCGGCTGCGCACCGATCTGGAACTGCAGGCGAAGGACCACGA
ACTCTTCACCACCGTGGTCAACGTGGAGCCTTTCGACTACGCACTGCGCTTCGGCGACTGCCACACCGAGATCCGCAATC
TCACCAACGGCTCCCTCCGCGACCTCGGCATCTTCATGTATGAACGCGGTAACGGCCAGGACCTGCGGATCGATTTCGAC
GCCCATGCCGATCTCTACACCGCGCCCGAACTGGCGGCGCACCAGGCCCGGCTGCTCGGCGTGCTCGACGCCCTGGCGGA
TCGTCCCGCGCAGGCCATCGGCTGCGTGGAGGTCATCTCCGCAGATGAACGCGAGGCCTTCCTGTCCAGATGCAGCGGCA
CGGTCCGCGCGGAGCCCGCGGCCCACCTCGCCGAATTGCTGGATGCCGGCCTGTCGCGCGATCCCGGCGCGGTCGCGCTG
CGCTTCGAAGGCCGCTCCATGACCCGGGGCGAACTCGACCGCAAGGCCCTGGATTGGGCCCACCGCCTGGCGGCCATGGG
CGCAGGCCCGGAACGCATCGTCGCGCTGGCGATCCCACGGTCGCTGGAGCTGGTGGCGGCCCTCGTCGCGGTCCTGAGAA
GCGGGGCGGCGTACCTGCCGATCGACCCGGACTTTCCCGCCGACCGGCTCGCCTTCATGCTGGACGACGCGCAGCCCGTG
TGCCTCATGACCACGGAGGAACTCTCCGGGCGCTTCGATGGCGGCATTGCGCGCTTCATCGTCGATGCCGCGGAGCCGCA
GGCCGGCATCCAGCCGCCAGCGCCTGCCGGCGCCCTGGCGTCCGCGACCCTGCACCCATCGCACCCGGCCTATGTCATCT
ACACGTCGGGATCCACGGGCAGGCCCAAGGGCGTCGTGGTGCCCCACTCCGCCATCGTCAACCGGCTGCGCTGGATGCAG
GCGGAGTACGGGCTGGAATCCAGCGACCGCGTGCTGCAGAAGACACCTTCGAGCTTCGACGTCTCGGCATGGGAGTTCTT
CTGGCCGCTGCTCGCGGGCGCAACGCTCGTGATCGCCCGGCCCGGCGGGCACCGCGATCCACCGTACCTGGCGGACCTCA
TCGCGCGGGAAGCAGTCACCACCGTCCACTTCGTGCCCTCGATGCTCGAGTTGTTCCTGCAGGAGCCTGCAGCGGCCGCG
TGCCATACGCTGCGCCGGGTGGTCTGCAGCGGCGAGGCACTGTCTGCGCCCCTGGCTGCGCGGTTCCACGGCATGCTGGG
GTGGTGCGCACTGCACAACCTCTACGGCCCCACCGAGGCGGCGGTGGACGTCACCGCATGGGCCTGTACGCACGAGGCAT
GTGCCGGCCTGGCGCGCATCCCGATCGGACGCCCCATCTGGAACACCCGGATGTACGTGCTGGACCCGGGCCTGCAACCC
TTGCCGGTGGGCGCCACCGGCGAGCTGTATATCGCGGGCGACGGCCTGGCGCTGGGCTACCTGAACCGTCCCGCGCTCAC
CGCGGAGCGCTTCATCGCGGATCCATACGGGCCGGCGGGCAGCCGCATGTACCGCACCGGAGACCTCGCGCGGTGGTGCG
ACGACGGCACGCTCGAATTCCTCGGGCGCTCCGATCACCAGGTGAAGATACGGGGCCTGCGCATCGAGCCGGGCGAAATC
GAATCGGCGCTGATGCGCCATCCCGGCGTGCAACAGGCGGCGGTGGTGGTCCGGGAGGACGCCGGCGGAAGCAAGGTGCT
GGTGGCGTACTGCGTGCCCGTTGCTGGCGACCGGCTGGACGACTTCTCCCTGAGGGCCCATGTGGCGCAACGCGTGCCCG
AGTACATGGTGCCTTCCGCCTTCGTCGTCCTGGCGGAACTGCCGCTGGGGCCGAGCGGCAAGCTCGATCGCAGGGCGCTT
CCCGCTCCCGACACCTGCGTTCCAGGCCTGGACTACGCCGCTCCGCGCACGGCCGCCGAGAAGACCCTGGCAGAGTTGTG
GGCCAGCGCACTCCATGTGGAGAAGGTCGGAATCCACGACAACTTCTTCGACCTTGGCGGGCATTCGCTCATGGCCATCC
AGCTCGGCATGAAGATCCGCGAGTACATGCACCCGGATTTCCCGCCGGCCGAACTCTACAGCCGGCACACCATCGCGGAG
CTCGCGCTCTGGTTCGACAGCAACGGCGGCATGCGTCCCGCCACCGACCTGAGGGCCCAGATCGCGCTGCCCGAGCACAT
CCGCAAGCCGGACCTGCCCGCGCCACCCGCCCGCCCCCAGCGGGTCTTCCTGACTGGCGCGAGCGGCTTCGTCGGCAGCT
ACCTGCTCGCCACGCTGTTGCGTGAAACGTCCGCCACCATCATCTGCCATGTGCGCGCACCCGACGAGCGCGCGGGCCTG
CAACGCCTGCAGCAGGTGCTGGCGGAGCGCCGCCTCGGCGGGGCGTGGGATGCCTCGCGCGTCGAAATCGCCACCGGCGA
TCTCGCAGCGGAGCGGCTCGGCATGACCGACGACGCCATCCGGCGCGTGGCCGAATGCGACGCCATCTACCACTGCGCCG
CACAGGTGGACTACCTTCATCCCTACGAGACCCTCAAGCCGTCCAACGTGGACAGCGTCGTCACGCTGCTGGAATGGACG
GCCCAGGGCCGGCCGAAGGCGCTGCACTATGTCTCCACGCTGGCCGTGATCGGCATGAACCCCGAAACACCCGTGGTGAC
CGAGCGCTCCGCCCTGTCCACACCCGACGGACTGGGAAGCGGCTACGCGAAGAGCAAGTGGGTGGCCGACCACCTGGCAC
GGGCCGCCCAGGCGCGGGGCCTGCCGGTGGCGATCTACCGCCTGGGCGCCGTCACGGGAGACAAGGCGCAGGCCGCCTGC
AACGACACCGACATGTTCTGGCGCGTGGCCCGGCTGTATGCGGAACTGGGGATGTCGCCCCAGCTGGACCTTCCCATCAA
CCTGACGCCCGTGGACGAGGTGGCGCGGGCCATCGTGCGGCTCTCGCTCCGGCAGGACTCGTGGGGCGAAGTCTTCCACC
TGCTCGGTTCCGATCCCATGCATGTCAACGACATGGGCGACGTGTTCCAGCAGATCGGCAGGCCGCTGCAACCCACGGAT
CTCGGCAACTGGCTGCACCATGCGCAACAGCGTCTCGCGATCACCCAGGACCTGGACCTGGCGGCGCTCCTGACGATCCT
GGACGGCTACGACCTGCACAACGCGGTGCCAGCGATCGTCTGCGCCGCGGCCACCCAGGAACGGCTGGAAGCCGCCGGGG
CGCCGATCCGCTCGGCGGACCGTGATCTGCTGCGGCGCTACTTCGAGAACCTCGGCATCGGCGACGCGGCCGGAGCCCCC
GGTGCGCAACCCGCCGTGGCCCTGGGCTGA

Upstream 100 bases:

>100_bases
CGCGGCTGTACCAACGGACCACCATCGCGGGCCCATGCCCGCGGCGGTCTGCCGGTCCGCCTCCCATTCCATCGTTGTCA
ACGAGCCGAACGGAGCAACC

Downstream 100 bases:

>100_bases
CACATCGCAGGAGACACCCAGCCATGGCACGCTACCTGCTCGCCGCCACCGCCCTGCCCGGACATGTCATGCCGGTCCTG
GCCGTGGCACGGCATCTCGT

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1449; Mature: 1449

Protein sequence:

>1449_residues
MRASHFPVQTLPLTAAQMGMWFGTRFASPEANFNLAEAIEIYGSFEPRLLLQALRTLCAEADSIRLRVADTPQGPRQWLE
AEFSGSISMLDFSGDGDPRASAEQWMADESSRRMDVEREPMWSSAVLRIAPDHHIWYQRGHHYAFDGFAAVVLARRAADL
YTALVNGTAAPADSELKPLSVLIEEDQAYRDSARALKDREYWMERMRDRPEPLTLAERRSNNIGGLLRHTAHWPAARVAA
LRDTAALHGGTLPQILIAATATYLYRMTGVSDLVIGVPVTARYNDRMRRVPGMVANAVPLRLSMRPEMPFTALLREVSQQ
MRKILRHQAYRYERLRTDLELQAKDHELFTTVVNVEPFDYALRFGDCHTEIRNLTNGSLRDLGIFMYERGNGQDLRIDFD
AHADLYTAPELAAHQARLLGVLDALADRPAQAIGCVEVISADEREAFLSRCSGTVRAEPAAHLAELLDAGLSRDPGAVAL
RFEGRSMTRGELDRKALDWAHRLAAMGAGPERIVALAIPRSLELVAALVAVLRSGAAYLPIDPDFPADRLAFMLDDAQPV
CLMTTEELSGRFDGGIARFIVDAAEPQAGIQPPAPAGALASATLHPSHPAYVIYTSGSTGRPKGVVVPHSAIVNRLRWMQ
AEYGLESSDRVLQKTPSSFDVSAWEFFWPLLAGATLVIARPGGHRDPPYLADLIAREAVTTVHFVPSMLELFLQEPAAAA
CHTLRRVVCSGEALSAPLAARFHGMLGWCALHNLYGPTEAAVDVTAWACTHEACAGLARIPIGRPIWNTRMYVLDPGLQP
LPVGATGELYIAGDGLALGYLNRPALTAERFIADPYGPAGSRMYRTGDLARWCDDGTLEFLGRSDHQVKIRGLRIEPGEI
ESALMRHPGVQQAAVVVREDAGGSKVLVAYCVPVAGDRLDDFSLRAHVAQRVPEYMVPSAFVVLAELPLGPSGKLDRRAL
PAPDTCVPGLDYAAPRTAAEKTLAELWASALHVEKVGIHDNFFDLGGHSLMAIQLGMKIREYMHPDFPPAELYSRHTIAE
LALWFDSNGGMRPATDLRAQIALPEHIRKPDLPAPPARPQRVFLTGASGFVGSYLLATLLRETSATIICHVRAPDERAGL
QRLQQVLAERRLGGAWDASRVEIATGDLAAERLGMTDDAIRRVAECDAIYHCAAQVDYLHPYETLKPSNVDSVVTLLEWT
AQGRPKALHYVSTLAVIGMNPETPVVTERSALSTPDGLGSGYAKSKWVADHLARAAQARGLPVAIYRLGAVTGDKAQAAC
NDTDMFWRVARLYAELGMSPQLDLPINLTPVDEVARAIVRLSLRQDSWGEVFHLLGSDPMHVNDMGDVFQQIGRPLQPTD
LGNWLHHAQQRLAITQDLDLAALLTILDGYDLHNAVPAIVCAAATQERLEAAGAPIRSADRDLLRRYFENLGIGDAAGAP
GAQPAVALG

Sequences:

>Translated_1449_residues
MRASHFPVQTLPLTAAQMGMWFGTRFASPEANFNLAEAIEIYGSFEPRLLLQALRTLCAEADSIRLRVADTPQGPRQWLE
AEFSGSISMLDFSGDGDPRASAEQWMADESSRRMDVEREPMWSSAVLRIAPDHHIWYQRGHHYAFDGFAAVVLARRAADL
YTALVNGTAAPADSELKPLSVLIEEDQAYRDSARALKDREYWMERMRDRPEPLTLAERRSNNIGGLLRHTAHWPAARVAA
LRDTAALHGGTLPQILIAATATYLYRMTGVSDLVIGVPVTARYNDRMRRVPGMVANAVPLRLSMRPEMPFTALLREVSQQ
MRKILRHQAYRYERLRTDLELQAKDHELFTTVVNVEPFDYALRFGDCHTEIRNLTNGSLRDLGIFMYERGNGQDLRIDFD
AHADLYTAPELAAHQARLLGVLDALADRPAQAIGCVEVISADEREAFLSRCSGTVRAEPAAHLAELLDAGLSRDPGAVAL
RFEGRSMTRGELDRKALDWAHRLAAMGAGPERIVALAIPRSLELVAALVAVLRSGAAYLPIDPDFPADRLAFMLDDAQPV
CLMTTEELSGRFDGGIARFIVDAAEPQAGIQPPAPAGALASATLHPSHPAYVIYTSGSTGRPKGVVVPHSAIVNRLRWMQ
AEYGLESSDRVLQKTPSSFDVSAWEFFWPLLAGATLVIARPGGHRDPPYLADLIAREAVTTVHFVPSMLELFLQEPAAAA
CHTLRRVVCSGEALSAPLAARFHGMLGWCALHNLYGPTEAAVDVTAWACTHEACAGLARIPIGRPIWNTRMYVLDPGLQP
LPVGATGELYIAGDGLALGYLNRPALTAERFIADPYGPAGSRMYRTGDLARWCDDGTLEFLGRSDHQVKIRGLRIEPGEI
ESALMRHPGVQQAAVVVREDAGGSKVLVAYCVPVAGDRLDDFSLRAHVAQRVPEYMVPSAFVVLAELPLGPSGKLDRRAL
PAPDTCVPGLDYAAPRTAAEKTLAELWASALHVEKVGIHDNFFDLGGHSLMAIQLGMKIREYMHPDFPPAELYSRHTIAE
LALWFDSNGGMRPATDLRAQIALPEHIRKPDLPAPPARPQRVFLTGASGFVGSYLLATLLRETSATIICHVRAPDERAGL
QRLQQVLAERRLGGAWDASRVEIATGDLAAERLGMTDDAIRRVAECDAIYHCAAQVDYLHPYETLKPSNVDSVVTLLEWT
AQGRPKALHYVSTLAVIGMNPETPVVTERSALSTPDGLGSGYAKSKWVADHLARAAQARGLPVAIYRLGAVTGDKAQAAC
NDTDMFWRVARLYAELGMSPQLDLPINLTPVDEVARAIVRLSLRQDSWGEVFHLLGSDPMHVNDMGDVFQQIGRPLQPTD
LGNWLHHAQQRLAITQDLDLAALLTILDGYDLHNAVPAIVCAAATQERLEAAGAPIRSADRDLLRRYFENLGIGDAAGAP
GAQPAVALG
>Mature_1449_residues
MRASHFPVQTLPLTAAQMGMWFGTRFASPEANFNLAEAIEIYGSFEPRLLLQALRTLCAEADSIRLRVADTPQGPRQWLE
AEFSGSISMLDFSGDGDPRASAEQWMADESSRRMDVEREPMWSSAVLRIAPDHHIWYQRGHHYAFDGFAAVVLARRAADL
YTALVNGTAAPADSELKPLSVLIEEDQAYRDSARALKDREYWMERMRDRPEPLTLAERRSNNIGGLLRHTAHWPAARVAA
LRDTAALHGGTLPQILIAATATYLYRMTGVSDLVIGVPVTARYNDRMRRVPGMVANAVPLRLSMRPEMPFTALLREVSQQ
MRKILRHQAYRYERLRTDLELQAKDHELFTTVVNVEPFDYALRFGDCHTEIRNLTNGSLRDLGIFMYERGNGQDLRIDFD
AHADLYTAPELAAHQARLLGVLDALADRPAQAIGCVEVISADEREAFLSRCSGTVRAEPAAHLAELLDAGLSRDPGAVAL
RFEGRSMTRGELDRKALDWAHRLAAMGAGPERIVALAIPRSLELVAALVAVLRSGAAYLPIDPDFPADRLAFMLDDAQPV
CLMTTEELSGRFDGGIARFIVDAAEPQAGIQPPAPAGALASATLHPSHPAYVIYTSGSTGRPKGVVVPHSAIVNRLRWMQ
AEYGLESSDRVLQKTPSSFDVSAWEFFWPLLAGATLVIARPGGHRDPPYLADLIAREAVTTVHFVPSMLELFLQEPAAAA
CHTLRRVVCSGEALSAPLAARFHGMLGWCALHNLYGPTEAAVDVTAWACTHEACAGLARIPIGRPIWNTRMYVLDPGLQP
LPVGATGELYIAGDGLALGYLNRPALTAERFIADPYGPAGSRMYRTGDLARWCDDGTLEFLGRSDHQVKIRGLRIEPGEI
ESALMRHPGVQQAAVVVREDAGGSKVLVAYCVPVAGDRLDDFSLRAHVAQRVPEYMVPSAFVVLAELPLGPSGKLDRRAL
PAPDTCVPGLDYAAPRTAAEKTLAELWASALHVEKVGIHDNFFDLGGHSLMAIQLGMKIREYMHPDFPPAELYSRHTIAE
LALWFDSNGGMRPATDLRAQIALPEHIRKPDLPAPPARPQRVFLTGASGFVGSYLLATLLRETSATIICHVRAPDERAGL
QRLQQVLAERRLGGAWDASRVEIATGDLAAERLGMTDDAIRRVAECDAIYHCAAQVDYLHPYETLKPSNVDSVVTLLEWT
AQGRPKALHYVSTLAVIGMNPETPVVTERSALSTPDGLGSGYAKSKWVADHLARAAQARGLPVAIYRLGAVTGDKAQAAC
NDTDMFWRVARLYAELGMSPQLDLPINLTPVDEVARAIVRLSLRQDSWGEVFHLLGSDPMHVNDMGDVFQQIGRPLQPTD
LGNWLHHAQQRLAITQDLDLAALLTILDGYDLHNAVPAIVCAAATQERLEAAGAPIRSADRDLLRRYFENLGIGDAAGAP
GAQPAVALG

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI38505220, Length=500, Percent_Identity=24.8, Blast_Score=108, Evalue=5e-23,
Organism=Homo sapiens, GI42544132, Length=499, Percent_Identity=23.2464929859719, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI45580730, Length=451, Percent_Identity=25.9423503325942, Blast_Score=105, Evalue=4e-22,
Organism=Homo sapiens, GI122937307, Length=501, Percent_Identity=22.9540918163673, Blast_Score=95, Evalue=6e-19,
Organism=Homo sapiens, GI115511026, Length=535, Percent_Identity=24.6728971962617, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI156151445, Length=377, Percent_Identity=24.6684350132626, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI187761345, Length=500, Percent_Identity=23.4, Blast_Score=85, Evalue=5e-16,
Organism=Homo sapiens, GI187761343, Length=500, Percent_Identity=23.4, Blast_Score=85, Evalue=5e-16,
Organism=Homo sapiens, GI13375727, Length=382, Percent_Identity=26.1780104712042, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI157311624, Length=477, Percent_Identity=21.8029350104822, Blast_Score=78, Evalue=5e-14,
Organism=Homo sapiens, GI157311622, Length=477, Percent_Identity=21.8029350104822, Blast_Score=78, Evalue=5e-14,
Organism=Homo sapiens, GI58082049, Length=472, Percent_Identity=22.4576271186441, Blast_Score=77, Evalue=2e-13,
Organism=Escherichia coli, GI1786801, Length=1062, Percent_Identity=36.5348399246704, Blast_Score=584, Evalue=1e-167,
Organism=Escherichia coli, GI1788107, Length=544, Percent_Identity=24.8161764705882, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1786810, Length=507, Percent_Identity=26.6272189349112, Blast_Score=98, Evalue=3e-21,
Organism=Escherichia coli, GI145693145, Length=519, Percent_Identity=26.0115606936416, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI221142682, Length=492, Percent_Identity=23.5772357723577, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI1789201, Length=365, Percent_Identity=25.7534246575342, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1790505, Length=559, Percent_Identity=23.2558139534884, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1786529, Length=553, Percent_Identity=24.4122965641953, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17556356, Length=503, Percent_Identity=28.4294234592445, Blast_Score=142, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32563687, Length=524, Percent_Identity=25.763358778626, Blast_Score=119, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32564420, Length=510, Percent_Identity=24.9019607843137, Blast_Score=108, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32564422, Length=510, Percent_Identity=24.9019607843137, Blast_Score=108, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17558820, Length=529, Percent_Identity=24.952741020794, Blast_Score=106, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17550940, Length=524, Percent_Identity=22.3282442748092, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17557194, Length=497, Percent_Identity=23.3400402414487, Blast_Score=92, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538037, Length=500, Percent_Identity=23.8, Blast_Score=89, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560140, Length=360, Percent_Identity=25.2777777777778, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71985884, Length=466, Percent_Identity=23.175965665236, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559526, Length=370, Percent_Identity=23.5135135135135, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560308, Length=364, Percent_Identity=25.5494505494505, Blast_Score=79, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994690, Length=361, Percent_Identity=22.1606648199446, Blast_Score=73, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994694, Length=361, Percent_Identity=22.1606648199446, Blast_Score=73, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994703, Length=361, Percent_Identity=22.1606648199446, Blast_Score=72, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=1215, Percent_Identity=25.761316872428, Blast_Score=366, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6319264, Length=550, Percent_Identity=24.7272727272727, Blast_Score=90, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319699, Length=488, Percent_Identity=23.3606557377049, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24648676, Length=543, Percent_Identity=32.5966850828729, Blast_Score=245, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24656500, Length=503, Percent_Identity=23.6580516898608, Blast_Score=102, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19922652, Length=515, Percent_Identity=22.3300970873786, Blast_Score=99, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24582852, Length=464, Percent_Identity=23.9224137931034, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648260, Length=528, Percent_Identity=23.1060606060606, Blast_Score=91, Evalue=6e-18,
Organism=Drosophila melanogaster, GI18859661, Length=488, Percent_Identity=23.7704918032787, Blast_Score=80, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24581924, Length=529, Percent_Identity=22.3062381852552, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI161076582, Length=497, Percent_Identity=20.3219315895372, Blast_Score=77, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356947, Length=502, Percent_Identity=20.5179282868526, Blast_Score=75, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 158362; Mature: 158362

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRASHFPVQTLPLTAAQMGMWFGTRFASPEANFNLAEAIEIYGSFEPRLLLQALRTLCAE
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCC
ADSIRLRVADTPQGPRQWLEAEFSGSISMLDFSGDGDPRASAEQWMADESSRRMDVEREP
CCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCC
MWSSAVLRIAPDHHIWYQRGHHYAFDGFAAVVLARRAADLYTALVNGTAAPADSELKPLS
CCCCCEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
VLIEEDQAYRDSARALKDREYWMERMRDRPEPLTLAERRSNNIGGLLRHTAHWPAARVAA
EEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHCCCCHHHHHH
LRDTAALHGGTLPQILIAATATYLYRMTGVSDLVIGVPVTARYNDRMRRVPGMVANAVPL
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCEEECCCHHHHHCCCHHHCCCCE
RLSMRPEMPFTALLREVSQQMRKILRHQAYRYERLRTDLELQAKDHELFTTVVNVEPFDY
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEEECCCHHH
ALRFGDCHTEIRNLTNGSLRDLGIFMYERGNGQDLRIDFDAHADLYTAPELAAHQARLLG
HEEECHHHHHHHHCCCCCHHHEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
VLDALADRPAQAIGCVEVISADEREAFLSRCSGTVRAEPAAHLAELLDAGLSRDPGAVAL
HHHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEEE
RFEGRSMTRGELDRKALDWAHRLAAMGAGPERIVALAIPRSLELVAALVAVLRSGAAYLP
EECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCHHHHHHHHHHHHHCCCEEEC
IDPDFPADRLAFMLDDAQPVCLMTTEELSGRFDGGIARFIVDAAEPQAGIQPPAPAGALA
CCCCCCHHHHHEEECCCCCEEEEEHHHHCCCCCCCHHHHEEECCCCCCCCCCCCCCCCHH
SATLHPSHPAYVIYTSGSTGRPKGVVVPHSAIVNRLRWMQAEYGLESSDRVLQKTPSSFD
CCEECCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCC
VSAWEFFWPLLAGATLVIARPGGHRDPPYLADLIAREAVTTVHFVPSMLELFLQEPAAAA
CHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
CHTLRRVVCSGEALSAPLAARFHGMLGWCALHNLYGPTEAAVDVTAWACTHEACAGLARI
HHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHCC
PIGRPIWNTRMYVLDPGLQPLPVGATGELYIAGDGLALGYLNRPALTAERFIADPYGPAG
CCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCEEEECCCCCCHHHHHHHCCCCCCCC
SRMYRTGDLARWCDDGTLEFLGRSDHQVKIRGLRIEPGEIESALMRHPGVQQAAVVVRED
CCEEECCCHHHHCCCCCCEECCCCCCEEEEEEEEECCHHHHHHHHHCCCCCCEEEEEEEC
AGGSKVLVAYCVPVAGDRLDDFSLRAHVAQRVPEYMVPSAFVVLAELPLGPSGKLDRRAL
CCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCHHHHCCHHEEHEEECCCCCCCCCCCCCC
PAPDTCVPGLDYAAPRTAAEKTLAELWASALHVEKVGIHDNFFDLGGHSLMAIQLGMKIR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHCCCCEEEEHHHHHHHH
EYMHPDFPPAELYSRHTIAELALWFDSNGGMRPATDLRAQIALPEHIRKPDLPAPPARPQ
HHCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHEECCHHHCCCCCCCCCCCCCC
RVFLTGASGFVGSYLLATLLRETSATIICHVRAPDERAGLQRLQQVLAERRLGGAWDASR
EEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCE
VEIATGDLAAERLGMTDDAIRRVAECDAIYHCAAQVDYLHPYETLKPSNVDSVVTLLEWT
EEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHH
AQGRPKALHYVSTLAVIGMNPETPVVTERSALSTPDGLGSGYAKSKWVADHLARAAQARG
CCCCCHHHHHHHHHHEEECCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
LPVAIYRLGAVTGDKAQAACNDTDMFWRVARLYAELGMSPQLDLPINLTPVDEVARAIVR
CEEEEEEECCCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
LSLRQDSWGEVFHLLGSDPMHVNDMGDVFQQIGRPLQPTDLGNWLHHAQQRLAITQDLDL
HHCCCCCHHHHHHHHCCCCCEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHH
AALLTILDGYDLHNAVPAIVCAAATQERLEAAGAPIRSADRDLLRRYFENLGIGDAAGAP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GAQPAVALG
CCCCCCCCC
>Mature Secondary Structure
MRASHFPVQTLPLTAAQMGMWFGTRFASPEANFNLAEAIEIYGSFEPRLLLQALRTLCAE
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCC
ADSIRLRVADTPQGPRQWLEAEFSGSISMLDFSGDGDPRASAEQWMADESSRRMDVEREP
CCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCC
MWSSAVLRIAPDHHIWYQRGHHYAFDGFAAVVLARRAADLYTALVNGTAAPADSELKPLS
CCCCCEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
VLIEEDQAYRDSARALKDREYWMERMRDRPEPLTLAERRSNNIGGLLRHTAHWPAARVAA
EEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHCCCCHHHHHH
LRDTAALHGGTLPQILIAATATYLYRMTGVSDLVIGVPVTARYNDRMRRVPGMVANAVPL
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCEEECCCHHHHHCCCHHHCCCCE
RLSMRPEMPFTALLREVSQQMRKILRHQAYRYERLRTDLELQAKDHELFTTVVNVEPFDY
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEEECCCHHH
ALRFGDCHTEIRNLTNGSLRDLGIFMYERGNGQDLRIDFDAHADLYTAPELAAHQARLLG
HEEECHHHHHHHHCCCCCHHHEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
VLDALADRPAQAIGCVEVISADEREAFLSRCSGTVRAEPAAHLAELLDAGLSRDPGAVAL
HHHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEEE
RFEGRSMTRGELDRKALDWAHRLAAMGAGPERIVALAIPRSLELVAALVAVLRSGAAYLP
EECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCHHHHHHHHHHHHHCCCEEEC
IDPDFPADRLAFMLDDAQPVCLMTTEELSGRFDGGIARFIVDAAEPQAGIQPPAPAGALA
CCCCCCHHHHHEEECCCCCEEEEEHHHHCCCCCCCHHHHEEECCCCCCCCCCCCCCCCHH
SATLHPSHPAYVIYTSGSTGRPKGVVVPHSAIVNRLRWMQAEYGLESSDRVLQKTPSSFD
CCEECCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCC
VSAWEFFWPLLAGATLVIARPGGHRDPPYLADLIAREAVTTVHFVPSMLELFLQEPAAAA
CHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
CHTLRRVVCSGEALSAPLAARFHGMLGWCALHNLYGPTEAAVDVTAWACTHEACAGLARI
HHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHCC
PIGRPIWNTRMYVLDPGLQPLPVGATGELYIAGDGLALGYLNRPALTAERFIADPYGPAG
CCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCEEEECCCCCCHHHHHHHCCCCCCCC
SRMYRTGDLARWCDDGTLEFLGRSDHQVKIRGLRIEPGEIESALMRHPGVQQAAVVVRED
CCEEECCCHHHHCCCCCCEECCCCCCEEEEEEEEECCHHHHHHHHHCCCCCCEEEEEEEC
AGGSKVLVAYCVPVAGDRLDDFSLRAHVAQRVPEYMVPSAFVVLAELPLGPSGKLDRRAL
CCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCHHHHCCHHEEHEEECCCCCCCCCCCCCC
PAPDTCVPGLDYAAPRTAAEKTLAELWASALHVEKVGIHDNFFDLGGHSLMAIQLGMKIR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHCCCCEEEEHHHHHHHH
EYMHPDFPPAELYSRHTIAELALWFDSNGGMRPATDLRAQIALPEHIRKPDLPAPPARPQ
HHCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHEECCHHHCCCCCCCCCCCCCC
RVFLTGASGFVGSYLLATLLRETSATIICHVRAPDERAGLQRLQQVLAERRLGGAWDASR
EEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCE
VEIATGDLAAERLGMTDDAIRRVAECDAIYHCAAQVDYLHPYETLKPSNVDSVVTLLEWT
EEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHH
AQGRPKALHYVSTLAVIGMNPETPVVTERSALSTPDGLGSGYAKSKWVADHLARAAQARG
CCCCCHHHHHHHHHHEEECCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
LPVAIYRLGAVTGDKAQAACNDTDMFWRVARLYAELGMSPQLDLPINLTPVDEVARAIVR
CEEEEEEECCCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
LSLRQDSWGEVFHLLGSDPMHVNDMGDVFQQIGRPLQPTDLGNWLHHAQQRLAITQDLDL
HHCCCCCHHHHHHHHCCCCCEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHH
AALLTILDGYDLHNAVPAIVCAAATQERLEAAGAPIRSADRDLLRRYFENLGIGDAAGAP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GAQPAVALG
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]