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The map label for this gene is trkA [H]

Identifier: 120613177

GI number: 120613177

Start: 5061002

End: 5062480

Strand: Reverse

Name: trkA [H]

Synonym: Aave_4544

Alternate gene names: 120613177

Gene position: 5062480-5061002 (Counterclockwise)

Preceding gene: 120613178

Following gene: 120613176

Centisome position: 94.58

GC content: 69.1

Gene sequence:

>1479_bases
ATGAAGATCATCATCCTGGGCGCGGGCCGCGTGGGCGAGAGCGTGGCCGACAGCCTGGTGTCCGAGAAGAACGATATCAC
CGTCATCGACACCGATGCCGGGCGCCTGCGCGACCTGGAGTCGCGTTTCGACCTGCGTGGTGTCGTGGGTAGCGGCATCG
ACCCCGATGTGCTCGCAGAGGCTGGCGCCGCCGATACCGACCTGCTCATCGCCTGCGCCGCGCTCGACGAAACCAACCTG
GTCTGCTGCAAGATCGCCCAGCTGCTCTTCAACATTCCCACGCGCATCGCACGCGTCCGTTCGTCGGGTTTCGGCACCGG
CGACGATCAGGGCCGGGCCCTGCTCGGCAAGGAGGGCTTCGCGGTGGATCGCATCATTTGCCCGGAAGAGTCTCTCACGC
GCTACATCGGCAAGCTCGTGCAGTACCCCGAGGCCCTGCAGGTGCGTGAATTCGCGGGCGGCCGTGCCTGCCTGGCCTCC
GTCCGGGCGCGGGGCGGCGCCCCGGTCGTGGGCATGCGCATCGCCGACGTGCGGGCCAGCGCTCCCGAAGTCGCCATGCG
CGTGGTCGCGATCTACCGCCGCTTTCCGGAGGAGCCCGACCGCTTCGTCGCCTGCGACGGCACGACCCGGATCGAGGCAG
GCGATGAAGTCTTCGTGCTCGCTGCCCGCGAGCAGGTCCCGCGGGTGCTGGCGGCACTGCACCAGCGCGGCGGCGTGCCG
CCGCGGCCGGTACGCCGCATCATGATCGCGGGCGGCGGTCGGGTGGGGCTGCGGCTCGCACGCCAGCTGGCGGAGCAGGG
GGGCTTCCACGTCAAGATCCTGGAATCGAATGCCGATCGCTGTACGGAGCTGGCCTCGGTGCTGCCCGCGGAGGTGCTCG
TGCTGCACGGGGACGCCACCGACGAAGACCTGCTCGGCGACGAATGCATCGAAGAGGTGGACCTGTTCCTCGCCATCACC
GACGACGACGAGGACAACATCATGGCCTGCCTGCTCGCCAAACGCATGGGCGCGAGCCGGGTGTTGGCGCTCATCAACCG
CCGCTCCTACGCCGACCTCATGCACGGCACGCAGATCGACATCGCGCTCTCGCCGGCACAGGCCATGCTGGGCGAACTGC
TCGCCTACGTGCGCCGCGGCGACGTCCAGGCGGTGCACAGTCTGCGCCGCGGCGTGGCGGAGGCGCTGGAAATCGTCGCC
CGCGGAGACCGCAAGAGCTCGCGCGTGGTCGGCCGCCGCGTCGGCGAACTGCACCTGCCGCACGACGTGCACATGGGCCT
CATCGTGCGCGGGCTCGGCGAACACGCCACGGCCGACGCGGGCGAGGGCATGTCGGTGCCTGCCGGTGAGCCCGAGGTCA
TCATTCCGCACAGCCATACCGTGATCGAAAGCGGCGACCATGTCGTCTTCTTCCTCCCGAACAAGCGGCTGGTGCGCGAA
GTGGAAAAGGCCTTCCGCGTGAGCGCGACGTTTTTCTGA

Upstream 100 bases:

>100_bases
CACCTCGCTCAAATGGGTGGTGCTCGGCGAGGGCGACATCCGCGCCTGAGCGGCCGCCTGCGGGCCTCCAGCCTCCAAAC
CCCTTCATCGTTCCTGCCGC

Downstream 100 bases:

>100_bases
TCGCGATGTCCGTGCCTTCCGCGCTTTCCGAGGCCCTGCCGGATCTGCTGCCGGTGCTGCGCGTGTTCGGCGCGTTGCTC
GCGATGTTCTCCTGGGCCCT

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MKIIILGAGRVGESVADSLVSEKNDITVIDTDAGRLRDLESRFDLRGVVGSGIDPDVLAEAGAADTDLLIACAALDETNL
VCCKIAQLLFNIPTRIARVRSSGFGTGDDQGRALLGKEGFAVDRIICPEESLTRYIGKLVQYPEALQVREFAGGRACLAS
VRARGGAPVVGMRIADVRASAPEVAMRVVAIYRRFPEEPDRFVACDGTTRIEAGDEVFVLAAREQVPRVLAALHQRGGVP
PRPVRRIMIAGGGRVGLRLARQLAEQGGFHVKILESNADRCTELASVLPAEVLVLHGDATDEDLLGDECIEEVDLFLAIT
DDDEDNIMACLLAKRMGASRVLALINRRSYADLMHGTQIDIALSPAQAMLGELLAYVRRGDVQAVHSLRRGVAEALEIVA
RGDRKSSRVVGRRVGELHLPHDVHMGLIVRGLGEHATADAGEGMSVPAGEPEVIIPHSHTVIESGDHVVFFLPNKRLVRE
VEKAFRVSATFF

Sequences:

>Translated_492_residues
MKIIILGAGRVGESVADSLVSEKNDITVIDTDAGRLRDLESRFDLRGVVGSGIDPDVLAEAGAADTDLLIACAALDETNL
VCCKIAQLLFNIPTRIARVRSSGFGTGDDQGRALLGKEGFAVDRIICPEESLTRYIGKLVQYPEALQVREFAGGRACLAS
VRARGGAPVVGMRIADVRASAPEVAMRVVAIYRRFPEEPDRFVACDGTTRIEAGDEVFVLAAREQVPRVLAALHQRGGVP
PRPVRRIMIAGGGRVGLRLARQLAEQGGFHVKILESNADRCTELASVLPAEVLVLHGDATDEDLLGDECIEEVDLFLAIT
DDDEDNIMACLLAKRMGASRVLALINRRSYADLMHGTQIDIALSPAQAMLGELLAYVRRGDVQAVHSLRRGVAEALEIVA
RGDRKSSRVVGRRVGELHLPHDVHMGLIVRGLGEHATADAGEGMSVPAGEPEVIIPHSHTVIESGDHVVFFLPNKRLVRE
VEKAFRVSATFF
>Mature_492_residues
MKIIILGAGRVGESVADSLVSEKNDITVIDTDAGRLRDLESRFDLRGVVGSGIDPDVLAEAGAADTDLLIACAALDETNL
VCCKIAQLLFNIPTRIARVRSSGFGTGDDQGRALLGKEGFAVDRIICPEESLTRYIGKLVQYPEALQVREFAGGRACLAS
VRARGGAPVVGMRIADVRASAPEVAMRVVAIYRRFPEEPDRFVACDGTTRIEAGDEVFVLAAREQVPRVLAALHQRGGVP
PRPVRRIMIAGGGRVGLRLARQLAEQGGFHVKILESNADRCTELASVLPAEVLVLHGDATDEDLLGDECIEEVDLFLAIT
DDDEDNIMACLLAKRMGASRVLALINRRSYADLMHGTQIDIALSPAQAMLGELLAYVRRGDVQAVHSLRRGVAEALEIVA
RGDRKSSRVVGRRVGELHLPHDVHMGLIVRGLGEHATADAGEGMSVPAGEPEVIIPHSHTVIESGDHVVFFLPNKRLVRE
VEKAFRVSATFF

Specific function: Part of the constitutive potassium transport systems trkG and trkH. May regulate the transport activity of trkG and trkH systems. Binds to NAD+ and NADH [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Peripherally bound to the inner side of the inner membrane via the trkG and trkH proteins (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=492, Percent_Identity=45.1219512195122, Blast_Score=407, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 53039; Mature: 53039

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIILGAGRVGESVADSLVSEKNDITVIDTDAGRLRDLESRFDLRGVVGSGIDPDVLAE
CEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
AGAADTDLLIACAALDETNLVCCKIAQLLFNIPTRIARVRSSGFGTGDDQGRALLGKEGF
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCC
AVDRIICPEESLTRYIGKLVQYPEALQVREFAGGRACLASVRARGGAPVVGMRIADVRAS
EECEEECCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEECCCCC
APEVAMRVVAIYRRFPEEPDRFVACDGTTRIEAGDEVFVLAAREQVPRVLAALHQRGGVP
CHHHHHHHHHHHHHCCCCCCCEEEECCCEEECCCCCEEEEECHHHHHHHHHHHHHCCCCC
PRPVRRIMIAGGGRVGLRLARQLAEQGGFHVKILESNADRCTELASVLPAEVLVLHGDAT
CHHHHEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCEEEEEEECCCC
DEDLLGDECIEEVDLFLAITDDDEDNIMACLLAKRMGASRVLALINRRSYADLMHGTQID
CHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEE
IALSPAQAMLGELLAYVRRGDVQAVHSLRRGVAEALEIVARGDRKSSRVVGRRVGELHLP
EEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
HDVHMGLIVRGLGEHATADAGEGMSVPAGEPEVIIPHSHTVIESGDHVVFFLPNKRLVRE
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEECCCEEEEECCCHHHHHH
VEKAFRVSATFF
HHHHHHHHCCCC
>Mature Secondary Structure
MKIIILGAGRVGESVADSLVSEKNDITVIDTDAGRLRDLESRFDLRGVVGSGIDPDVLAE
CEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
AGAADTDLLIACAALDETNLVCCKIAQLLFNIPTRIARVRSSGFGTGDDQGRALLGKEGF
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCC
AVDRIICPEESLTRYIGKLVQYPEALQVREFAGGRACLASVRARGGAPVVGMRIADVRAS
EECEEECCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEECCCCC
APEVAMRVVAIYRRFPEEPDRFVACDGTTRIEAGDEVFVLAAREQVPRVLAALHQRGGVP
CHHHHHHHHHHHHHCCCCCCCEEEECCCEEECCCCCEEEEECHHHHHHHHHHHHHCCCCC
PRPVRRIMIAGGGRVGLRLARQLAEQGGFHVKILESNADRCTELASVLPAEVLVLHGDAT
CHHHHEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCEEEEEEECCCC
DEDLLGDECIEEVDLFLAITDDDEDNIMACLLAKRMGASRVLALINRRSYADLMHGTQID
CHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEE
IALSPAQAMLGELLAYVRRGDVQAVHSLRRGVAEALEIVARGDRKSSRVVGRRVGELHLP
EEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
HDVHMGLIVRGLGEHATADAGEGMSVPAGEPEVIIPHSHTVIESGDHVVFFLPNKRLVRE
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEECCCEEEEECCCHHHHHH
VEKAFRVSATFF
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]