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The map label for this gene is ntrY [H]

Identifier: 120613159

GI number: 120613159

Start: 5028908

End: 5031226

Strand: Reverse

Name: ntrY [H]

Synonym: Aave_4526

Alternate gene names: 120613159

Gene position: 5031226-5028908 (Counterclockwise)

Preceding gene: 120613160

Following gene: 120613158

Centisome position: 93.99

GC content: 70.98

Gene sequence:

>2319_bases
ATGAGCCCCTCTCCTTCCGATCCCGCCTCGCCCCGGGAACCCGTGACGGTCCGTAGCGGCCGGCAGGCCCGCGCCGCGCG
CTGGGCGCTGGGCGTGTCCGTCGCCGTGATGAGCGCCATCGGCCTCGTGCTGCTGTTCCTGCTCACCGTCTCGACGAACA
ACCGGGCGATGTACGAACGCAACTACGCGTGGCTTTTCGGGCTGAACGTGCTGGTGGCGCTGCTGCTCTTCGCGGTGCTG
GCCTGGGTGGCCGTGCGCCTGGCGGTGCGGCTGCGCAAGGGCCGCTTCGGCAGCCGGCTGCTGGTGAAGCTGGCGGGCAT
CTTCGGGCTGGTGGGGCTGGTGCCCGGGCTGCTGATCTACGTGGTGTCCTACCAGTTCGTGTCGCGGTCCATCGAGAGCT
GGTTCGACGTGAAGGTGGAGGGTGCCCTGTCGGCTGGCGTGAGCCTGGCCCGGGCCACGCTGGACACGCTGGCCAGCGAC
ATGGCGGCGCAGGCGCGCACGGCCAGCATCCAGCTGGCGCCGGTGCCGGATGCCGCCGCGGGCCTGGTGCTGGAACGCAT
TCGCGACCAGCTGGGCGCGACGGACGTGGTGCTTTTCAACTCGGCGGGGCAGGCGGTGGCGAGCGCCGGCCAGTCCCGCT
TCGACCTCAATCCGGAGCGGCCGGCCCCGCAGCTGCTGCGCAATGCCCGGCAGCAGCGCTCCGCCTTCCAGATCGAGGGG
CTGGACGAAGCCGCCGACCCGCAGGCCGTGCAGAACGCGCGGGTGAAGACGCTGGTGATGGTGGGCACCACGAGCGTGGG
CCTGCTGGAAGAGCCGCGCTACCTGCAGGCCACGATGCGCCTGCCGCAGGTGGTGGTGGCCAACGCCCTGGCCGTGCAGG
AGGCGAACCGTGAGTACCAGGAGCGCGCGCTGGCCCGCGGCGGGCTGCGGCGCATGTACATCGGCACGCTCACGCTCAGC
CTGTTCCTGGCGGTGTTCGGCGCCGTGCTGCTGGCCGTTCTGCTGGGCCGGCATCTGGCGAGGCCGCTGCTGGTGCTCGC
CGAGGGCGTGCGCGAGGTGGCCTCGGGCAACCTGAGCCCCAAGGCGGTACTGCAGACGGGCGACGAACTCGGCGGGCTGA
CACGCTCCTTCGCGGTCATGACGCAGCAGCTGGCCGATGCGCGGTCCGCGGTGGAGCGCAGCATGGGCGAGGTGGATGCC
GCGCGCGCGCGCCTGCAGACCATCCTGGACAACCTGACGGCCGGCGTGATCGTGCTGGACGCGCAGGGCCGCATCCAGTC
CACCAACCCGGGTGCCACCCGCATCCTGCGTGCGCCCATGGCGGCGTTCGAGGGCCGGCCGCTGGCGGAGGTGCCGGGGC
TGGCGGCGTTCGCGGCGGCCGTGCAGGCACATTTCGACGCCTTCCTGGGCGACCGCGAGCAGCAGCACGGGCTGGACCAC
TGGCAGCACCCGTTCGACCTGCACGTGGGGGGAGGGGATCCCACCCATGCGGGGCCGGCCGGCAACGGAACGAGCCTGGT
GGCGCGGGGCGCGGAGCTGCCCGACGCGCTGCGGCTGCTGGTGTTCGACGACATCTCCGAGATCGTCTCCGCCCAGCGGG
CCCAGGCGTGGGGCGAGGTCGCGCGCCGGCTGGCGCACGAGATCAAGAACCCGCTCACGCCGATCCAGCTGTCGGCCGAG
CGGCTGGAGATGAAGCTGACCGGCAAGCTGGGCGCCGCGGAGGAGGCGGTGCTGGCCAAGTCGGTCAAGACCATCGTCGA
TCAGGTGGATGCCATGAAGCGCCTGGTCAACGAGTTCCGCGACTATGCGCGGTTGCCCGCTGCCGAACTGCAGCGCCTGG
ACCTGAACGCGCTGGTGGGCGACATCCTGCACCTGTATGGAGCGGAGACCGCCACGGTGCCGGTGGAGTCCGAGCTCGAC
CCGCGGTGCCCGGCGATCGCCGGCGACGCCCAGCAACTGCGGCAGGTGATCCACAACCTGCTGCAGAACGCACAGGATGC
GAGCGAGCAGCGTGCCCGTGAAGAGGGGGTGGCGCCCGCCCCGGTGCGCATCGCCACGCGCTGGAGCGAGACCTCGCGCC
GGGTGCGCCTGACGGTGAGCGATGCCGGTACGGGCTTCCCGGCTCACATCCTGCAAAGGGCCTTCGAGCCCTATGTCACC
ACCAAGCCGCGTGGCACCGGCCTGGGCCTGGCGGTGGTGAAAAAAATCGCCGACGAACATGGGGCGCGCATCGATCTTTC
CAATCGCGTGGAAGACGGCGTGGTCCGGGGGGCACAAGTGTCGCTATCATTCGCGCCTGAAACCCCCGTGGTTTATTAA

Upstream 100 bases:

>100_bases
TGTCGCAGCTGCCGAGGCCGTTCCAGATCGGCGCCATGGGGCGCTCCGGATGGGACCTCGCGATTTCCCGCGCCGAACGC
CTGGTCATCGAGCCGCAGCC

Downstream 100 bases:

>100_bases
CAACACGTTACACGCAGCCCGCAGCAGCATCCGTACCCATGGCAAATATATTGGTGGTTGACGACGAACTCGGTATCCGC
GACTTGCTGTCCGAAATCCT

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 772; Mature: 771

Protein sequence:

>772_residues
MSPSPSDPASPREPVTVRSGRQARAARWALGVSVAVMSAIGLVLLFLLTVSTNNRAMYERNYAWLFGLNVLVALLLFAVL
AWVAVRLAVRLRKGRFGSRLLVKLAGIFGLVGLVPGLLIYVVSYQFVSRSIESWFDVKVEGALSAGVSLARATLDTLASD
MAAQARTASIQLAPVPDAAAGLVLERIRDQLGATDVVLFNSAGQAVASAGQSRFDLNPERPAPQLLRNARQQRSAFQIEG
LDEAADPQAVQNARVKTLVMVGTTSVGLLEEPRYLQATMRLPQVVVANALAVQEANREYQERALARGGLRRMYIGTLTLS
LFLAVFGAVLLAVLLGRHLARPLLVLAEGVREVASGNLSPKAVLQTGDELGGLTRSFAVMTQQLADARSAVERSMGEVDA
ARARLQTILDNLTAGVIVLDAQGRIQSTNPGATRILRAPMAAFEGRPLAEVPGLAAFAAAVQAHFDAFLGDREQQHGLDH
WQHPFDLHVGGGDPTHAGPAGNGTSLVARGAELPDALRLLVFDDISEIVSAQRAQAWGEVARRLAHEIKNPLTPIQLSAE
RLEMKLTGKLGAAEEAVLAKSVKTIVDQVDAMKRLVNEFRDYARLPAAELQRLDLNALVGDILHLYGAETATVPVESELD
PRCPAIAGDAQQLRQVIHNLLQNAQDASEQRAREEGVAPAPVRIATRWSETSRRVRLTVSDAGTGFPAHILQRAFEPYVT
TKPRGTGLGLAVVKKIADEHGARIDLSNRVEDGVVRGAQVSLSFAPETPVVY

Sequences:

>Translated_772_residues
MSPSPSDPASPREPVTVRSGRQARAARWALGVSVAVMSAIGLVLLFLLTVSTNNRAMYERNYAWLFGLNVLVALLLFAVL
AWVAVRLAVRLRKGRFGSRLLVKLAGIFGLVGLVPGLLIYVVSYQFVSRSIESWFDVKVEGALSAGVSLARATLDTLASD
MAAQARTASIQLAPVPDAAAGLVLERIRDQLGATDVVLFNSAGQAVASAGQSRFDLNPERPAPQLLRNARQQRSAFQIEG
LDEAADPQAVQNARVKTLVMVGTTSVGLLEEPRYLQATMRLPQVVVANALAVQEANREYQERALARGGLRRMYIGTLTLS
LFLAVFGAVLLAVLLGRHLARPLLVLAEGVREVASGNLSPKAVLQTGDELGGLTRSFAVMTQQLADARSAVERSMGEVDA
ARARLQTILDNLTAGVIVLDAQGRIQSTNPGATRILRAPMAAFEGRPLAEVPGLAAFAAAVQAHFDAFLGDREQQHGLDH
WQHPFDLHVGGGDPTHAGPAGNGTSLVARGAELPDALRLLVFDDISEIVSAQRAQAWGEVARRLAHEIKNPLTPIQLSAE
RLEMKLTGKLGAAEEAVLAKSVKTIVDQVDAMKRLVNEFRDYARLPAAELQRLDLNALVGDILHLYGAETATVPVESELD
PRCPAIAGDAQQLRQVIHNLLQNAQDASEQRAREEGVAPAPVRIATRWSETSRRVRLTVSDAGTGFPAHILQRAFEPYVT
TKPRGTGLGLAVVKKIADEHGARIDLSNRVEDGVVRGAQVSLSFAPETPVVY
>Mature_771_residues
SPSPSDPASPREPVTVRSGRQARAARWALGVSVAVMSAIGLVLLFLLTVSTNNRAMYERNYAWLFGLNVLVALLLFAVLA
WVAVRLAVRLRKGRFGSRLLVKLAGIFGLVGLVPGLLIYVVSYQFVSRSIESWFDVKVEGALSAGVSLARATLDTLASDM
AAQARTASIQLAPVPDAAAGLVLERIRDQLGATDVVLFNSAGQAVASAGQSRFDLNPERPAPQLLRNARQQRSAFQIEGL
DEAADPQAVQNARVKTLVMVGTTSVGLLEEPRYLQATMRLPQVVVANALAVQEANREYQERALARGGLRRMYIGTLTLSL
FLAVFGAVLLAVLLGRHLARPLLVLAEGVREVASGNLSPKAVLQTGDELGGLTRSFAVMTQQLADARSAVERSMGEVDAA
RARLQTILDNLTAGVIVLDAQGRIQSTNPGATRILRAPMAAFEGRPLAEVPGLAAFAAAVQAHFDAFLGDREQQHGLDHW
QHPFDLHVGGGDPTHAGPAGNGTSLVARGAELPDALRLLVFDDISEIVSAQRAQAWGEVARRLAHEIKNPLTPIQLSAER
LEMKLTGKLGAAEEAVLAKSVKTIVDQVDAMKRLVNEFRDYARLPAAELQRLDLNALVGDILHLYGAETATVPVESELDP
RCPAIAGDAQQLRQVIHNLLQNAQDASEQRAREEGVAPAPVRIATRWSETSRRVRLTVSDAGTGFPAHILQRAFEPYVTT
KPRGTGLGLAVVKKIADEHGARIDLSNRVEDGVVRGAQVSLSFAPETPVVY

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=419, Percent_Identity=24.582338902148, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=32.6086956521739, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1790300, Length=362, Percent_Identity=25.9668508287293, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=27.027027027027, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82866; Mature: 82735

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPSPSDPASPREPVTVRSGRQARAARWALGVSVAVMSAIGLVLLFLLTVSTNNRAMYER
CCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
NYAWLFGLNVLVALLLFAVLAWVAVRLAVRLRKGRFGSRLLVKLAGIFGLVGLVPGLLIY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VVSYQFVSRSIESWFDVKVEGALSAGVSLARATLDTLASDMAAQARTASIQLAPVPDAAA
HHHHHHHHHHHHHHHCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHH
GLVLERIRDQLGATDVVLFNSAGQAVASAGQSRFDLNPERPAPQLLRNARQQRSAFQIEG
HHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECC
LDEAADPQAVQNARVKTLVMVGTTSVGLLEEPRYLQATMRLPQVVVANALAVQEANREYQ
CCCCCCCHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERALARGGLRRMYIGTLTLSLFLAVFGAVLLAVLLGRHLARPLLVLAEGVREVASGNLSP
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KAVLQTGDELGGLTRSFAVMTQQLADARSAVERSMGEVDAARARLQTILDNLTAGVIVLD
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
AQGRIQSTNPGATRILRAPMAAFEGRPLAEVPGLAAFAAAVQAHFDAFLGDREQQHGLDH
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHCCCHHHCCCHH
WQHPFDLHVGGGDPTHAGPAGNGTSLVARGAELPDALRLLVFDDISEIVSAQRAQAWGEV
CCCCCEEEECCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRLAHEIKNPLTPIQLSAERLEMKLTGKLGAAEEAVLAKSVKTIVDQVDAMKRLVNEFR
HHHHHHHHHCCCCCCEECHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYARLPAAELQRLDLNALVGDILHLYGAETATVPVESELDPRCPAIAGDAQQLRQVIHNL
HHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
LQNAQDASEQRAREEGVAPAPVRIATRWSETSRRVRLTVSDAGTGFPAHILQRAFEPYVT
HHHHHHHHHHHHHHCCCCCCCEEEEECHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCCC
TKPRGTGLGLAVVKKIADEHGARIDLSNRVEDGVVRGAQVSLSFAPETPVVY
CCCCCCCHHHHHHHHHHHHCCCEEECHHHHHHHHCCCCEEEEEECCCCCCCC
>Mature Secondary Structure 
SPSPSDPASPREPVTVRSGRQARAARWALGVSVAVMSAIGLVLLFLLTVSTNNRAMYER
CCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
NYAWLFGLNVLVALLLFAVLAWVAVRLAVRLRKGRFGSRLLVKLAGIFGLVGLVPGLLIY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VVSYQFVSRSIESWFDVKVEGALSAGVSLARATLDTLASDMAAQARTASIQLAPVPDAAA
HHHHHHHHHHHHHHHCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHH
GLVLERIRDQLGATDVVLFNSAGQAVASAGQSRFDLNPERPAPQLLRNARQQRSAFQIEG
HHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECC
LDEAADPQAVQNARVKTLVMVGTTSVGLLEEPRYLQATMRLPQVVVANALAVQEANREYQ
CCCCCCCHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERALARGGLRRMYIGTLTLSLFLAVFGAVLLAVLLGRHLARPLLVLAEGVREVASGNLSP
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KAVLQTGDELGGLTRSFAVMTQQLADARSAVERSMGEVDAARARLQTILDNLTAGVIVLD
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
AQGRIQSTNPGATRILRAPMAAFEGRPLAEVPGLAAFAAAVQAHFDAFLGDREQQHGLDH
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHCCCHHHCCCHH
WQHPFDLHVGGGDPTHAGPAGNGTSLVARGAELPDALRLLVFDDISEIVSAQRAQAWGEV
CCCCCEEEECCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRLAHEIKNPLTPIQLSAERLEMKLTGKLGAAEEAVLAKSVKTIVDQVDAMKRLVNEFR
HHHHHHHHHCCCCCCEECHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYARLPAAELQRLDLNALVGDILHLYGAETATVPVESELDPRCPAIAGDAQQLRQVIHNL
HHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
LQNAQDASEQRAREEGVAPAPVRIATRWSETSRRVRLTVSDAGTGFPAHILQRAFEPYVT
HHHHHHHHHHHHHHCCCCCCCEEEEECHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCCC
TKPRGTGLGLAVVKKIADEHGARIDLSNRVEDGVVRGAQVSLSFAPETPVVY
CCCCCCCHHHHHHHHHHHHCCCEEECHHHHHHHHCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]