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The map label for this gene is nreB [H]

Identifier: 120613017

GI number: 120613017

Start: 4873798

End: 4874916

Strand: Direct

Name: nreB [H]

Synonym: Aave_4381

Alternate gene names: 120613017

Gene position: 4873798-4874916 (Clockwise)

Preceding gene: 120613009

Following gene: 120613018

Centisome position: 91.05

GC content: 67.02

Gene sequence:

>1119_bases
ATGGCCTCAGGAGTAATGGTTAAACCCCTGCGCATCCTGCATCTCGAAGATTCCCTTGCGGACCATGCTTTGGCATGTAT
TACGTTGCGCCGCGCCAACGGGATGTATGAAATTCGCCACGCAGACACGATGGAATCCTTCGTGGCCTGGCTGGATGCGG
AGCGATTCGATCTCGTCCTCGCCGACTACCGGCTGCCGGGCTTCACGGCGCTGGATGCATGGCGCTGGGTGAGCGAGCGC
GGCGAGCCCCCGCCCTTCGTGCTGCTGTCCGGCGCCATCGGCGAGGCCGCCGCCGTGGATGCGATGCGCCTGGGCATGGC
GGACTACCTCCTGAAGGACGACATGGCCCGGCTGCCGCACGTGATCGGTCGCGCCATCGAGGTGCATGAGGCACGCAGGG
CGCGGGAGCAGGCGGTGCGCGACCTCGCGGCATCGGAGAGACAGCTGGCGGAACTGACCGAGCACCTGCAGATTTCCATC
GAGCGGGAGCGTGCGGCGATCGCCCGCGAGATCCACGACGACATCGGCGGTGCCCTGACGGCGGTGCGCTTCGACGTGGG
GTGGATCGCACGGCACTCCACGGAACCGGCGGTGCTCGGCCATGCCGGCAGCGCGACGGAGATGCTGCAGCATGCCATCG
AGGCGAGCCAGCGCATCATGATGAATCTGCGCCCGCCCATCCTCGACCAGGGGTTGGTGGCCGCGGTGCAGTGGCTGGCC
GAGAGCTTCGAGCGCCGCACGGGCATTCCCACCCGGCTGCATTCCAGTCGCGATGCGATCGAGGTGCCGGGCGACGTGCA
GCTGGTGGCCTACCGCACGGCGCAGGAGGCCCTGACCAACGTATCGAAATACGCACAGGCCAGCCAGGTGTCGATCGACC
TCTCGGACAGCGAGCGCGTGCTGACGCTGGAGGTGACGGACAATGGCTGCGGCATGGAACCTGCCATGCGGAACAAGCCG
AAGTCCTTCGGGCTCAAGGGCCTGCAGGAACGGGCGAGAACGGTCGGAGGGTGGCTGGACATCAGCAGCCAGCCGGGACG
CGGCACCTCGGTCATCGTGTCGATCCCGCTGGAGCCGCAGGACAGCCAGGGCGCCGAGGACCCAGGAGAATTGCCATGA

Upstream 100 bases:

>100_bases
CAACGACGCGTCGCCTGGTAGGCGATGCGCTCCCGCAGGGCGCAAACAGCGCATCTTGGCACGCTGTTTGTTCCAATATG
TATCCTATGATAGCGTTCAT

Downstream 100 bases:

>100_bases
TCCACGTCGTGCTGTGCGACGACCATGCCGTGCTGCGGCGCGGCATCCGCGACACGCTCACCGAAGCGCCGGACATCCAG
GTGACCGGGGAGGCCGGCGG

Product: response regulator receiver sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MASGVMVKPLRILHLEDSLADHALACITLRRANGMYEIRHADTMESFVAWLDAERFDLVLADYRLPGFTALDAWRWVSER
GEPPPFVLLSGAIGEAAAVDAMRLGMADYLLKDDMARLPHVIGRAIEVHEARRAREQAVRDLAASERQLAELTEHLQISI
ERERAAIAREIHDDIGGALTAVRFDVGWIARHSTEPAVLGHAGSATEMLQHAIEASQRIMMNLRPPILDQGLVAAVQWLA
ESFERRTGIPTRLHSSRDAIEVPGDVQLVAYRTAQEALTNVSKYAQASQVSIDLSDSERVLTLEVTDNGCGMEPAMRNKP
KSFGLKGLQERARTVGGWLDISSQPGRGTSVIVSIPLEPQDSQGAEDPGELP

Sequences:

>Translated_372_residues
MASGVMVKPLRILHLEDSLADHALACITLRRANGMYEIRHADTMESFVAWLDAERFDLVLADYRLPGFTALDAWRWVSER
GEPPPFVLLSGAIGEAAAVDAMRLGMADYLLKDDMARLPHVIGRAIEVHEARRAREQAVRDLAASERQLAELTEHLQISI
ERERAAIAREIHDDIGGALTAVRFDVGWIARHSTEPAVLGHAGSATEMLQHAIEASQRIMMNLRPPILDQGLVAAVQWLA
ESFERRTGIPTRLHSSRDAIEVPGDVQLVAYRTAQEALTNVSKYAQASQVSIDLSDSERVLTLEVTDNGCGMEPAMRNKP
KSFGLKGLQERARTVGGWLDISSQPGRGTSVIVSIPLEPQDSQGAEDPGELP
>Mature_371_residues
ASGVMVKPLRILHLEDSLADHALACITLRRANGMYEIRHADTMESFVAWLDAERFDLVLADYRLPGFTALDAWRWVSERG
EPPPFVLLSGAIGEAAAVDAMRLGMADYLLKDDMARLPHVIGRAIEVHEARRAREQAVRDLAASERQLAELTEHLQISIE
RERAAIAREIHDDIGGALTAVRFDVGWIARHSTEPAVLGHAGSATEMLQHAIEASQRIMMNLRPPILDQGLVAAVQWLAE
SFERRTGIPTRLHSSRDAIEVPGDVQLVAYRTAQEALTNVSKYAQASQVSIDLSDSERVLTLEVTDNGCGMEPAMRNKPK
SFGLKGLQERARTVGGWLDISSQPGRGTSVIVSIPLEPQDSQGAEDPGELP

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=227, Percent_Identity=31.7180616740088, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787474, Length=204, Percent_Identity=26.4705882352941, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788812, Length=203, Percent_Identity=25.1231527093596, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40840; Mature: 40709

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGVMVKPLRILHLEDSLADHALACITLRRANGMYEIRHADTMESFVAWLDAERFDLVL
CCCCCEECCEEEEEEHHHHHHHHHHHHEECCCCCEEEEHHHHHHHHHHHHHCCCHHEEEE
ADYRLPGFTALDAWRWVSERGEPPPFVLLSGAIGEAAAVDAMRLGMADYLLKDDMARLPH
ECCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VIGRAIEVHEARRAREQAVRDLAASERQLAELTEHLQISIERERAAIAREIHDDIGGALT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHH
AVRFDVGWIARHSTEPAVLGHAGSATEMLQHAIEASQRIMMNLRPPILDQGLVAAVQWLA
HEEECHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ESFERRTGIPTRLHSSRDAIEVPGDVQLVAYRTAQEALTNVSKYAQASQVSIDLSDSERV
HHHHHHCCCCCHHCCCCCCEECCCCEEEEEEHHHHHHHHHHHHHHHHHEEEEEECCCCEE
LTLEVTDNGCGMEPAMRNKPKSFGLKGLQERARTVGGWLDISSQPGRGTSVIVSIPLEPQ
EEEEEECCCCCCCCHHHCCCHHCCHHHHHHHHHHHCCEEECCCCCCCCCEEEEEECCCCC
DSQGAEDPGELP
CCCCCCCCCCCC
>Mature Secondary Structure 
ASGVMVKPLRILHLEDSLADHALACITLRRANGMYEIRHADTMESFVAWLDAERFDLVL
CCCCEECCEEEEEEHHHHHHHHHHHHEECCCCCEEEEHHHHHHHHHHHHHCCCHHEEEE
ADYRLPGFTALDAWRWVSERGEPPPFVLLSGAIGEAAAVDAMRLGMADYLLKDDMARLPH
ECCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VIGRAIEVHEARRAREQAVRDLAASERQLAELTEHLQISIERERAAIAREIHDDIGGALT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHH
AVRFDVGWIARHSTEPAVLGHAGSATEMLQHAIEASQRIMMNLRPPILDQGLVAAVQWLA
HEEECHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ESFERRTGIPTRLHSSRDAIEVPGDVQLVAYRTAQEALTNVSKYAQASQVSIDLSDSERV
HHHHHHCCCCCHHCCCCCCEECCCCEEEEEEHHHHHHHHHHHHHHHHHEEEEEECCCCEE
LTLEVTDNGCGMEPAMRNKPKSFGLKGLQERARTVGGWLDISSQPGRGTSVIVSIPLEPQ
EEEEEECCCCCCCCHHHCCCHHCCHHHHHHHHHHHCCEEECCCCCCCCCEEEEEECCCCC
DSQGAEDPGELP
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]