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The map label for this gene is virA [H]

Identifier: 120611809

GI number: 120611809

Start: 3476255

End: 3478507

Strand: Direct

Name: virA [H]

Synonym: Aave_3149

Alternate gene names: 120611809

Gene position: 3476255-3478507 (Clockwise)

Preceding gene: 120611808

Following gene: 120611810

Centisome position: 64.94

GC content: 72.79

Gene sequence:

>2253_bases
ATGAGCCGCCCCGACCTGTCCTTCCTGCTGCCGCCCGACCCGGAGGATGACCGCGGGACGGCGTCCGGCAGCGGGCCCGC
GGGCCCGGCCGGCGAGCCTGCCGGGCCTCCGGGCGACGGCGGCGACAACCGCCGCCAGCCCGGCCGTCCGGAAGGCCCCG
TGGCCGCGCTCATCGCGGAACTGCGCGCCTACCAGGCGGAACTGGAGGTGCAGAACAAGGTACTGCGCTACAGCCAGGCC
GCCGCGGAGAGCGCGTCCGAACGCTTCGAGACGCTGTTCGCCAGCGTGCCGCTGGCGCTCATGGTGCTGGACGAGCACGA
CATGGTGGTGCAGGCCAATTCGATGGCGCACCGCTGCTTCCAGCCCACCGAGTCGGACCGCCCCCTGACCTCGCTCATGC
CTTTCGTCAGTGCCGCGGACGCCGCCCGCGTGCGCGCCACGTTCGAGCAGGCCCGGGACCATGGCCACGGCGAGGCCAGC
GAGGTGGTGTTTCCCATCGGCGACGGGGACGCGGGCATCATCGGCGACCTGTATATCGCGCGCATCGAGGCCCCCCAGGC
GGACGGCGCCCCGGAGCAGTGGCAGTTCCTCTGCGCCGTGGTGGACCAGGGCCCGCTGGTGGCCGAGCGCCGCGCCCTGC
AGCAGAGCGCCACGGCCCTGCAGGAGCGCAACGTCCAGCTCTACGCCAGCGAGCGCCGCCTGGAGGCCGTCATCAATTCC
GCGCTGGACGCCATCATCTGCGTGGACCAGAACCAGCGCATCACCGTCTTCAACCCCACTGCCGCGGCCCTGTTCCAGTG
CGCCACGGCCGATGCGCTGGGCAGCCCCCTCGACCGTTTCCTGCCCGATGCCGTCCAGGCCCTGACCTTCGCCCAGCTGG
CCACCCAGGCCGTGCTCGGCGAGATGGTCGCGCTCACGGCCAGCGGCAAGGAACTGGCGGTGGAAGTGAGCGTGTCGTTC
GAGCGGCACGCCGAGGGAGAGACCACCACCGTGTTCGCGCGCGACCTCACCGGCCGCAAGAAGGCCGAGGCGCACCGCAA
CGAGCTGGAGGCGCAGCTGCGCGAATCCCACAAGATGCAGGCCGTGGGCACCATGGCCGGCGGGATCGCGCACGATTTCA
ACAACATCCTGAGCGCCATCCTCGGCAACGTGGAACTGGCCAAGGCGGACTGCGCCGCCGGCTCCCCGGTGCTGGAGAGC
CTGCGCGAGATCGAGAAGGCCGGCCGGCGCGCGCGCGACCTCGTCCGGCAGATCCTCACCTTCAGCCGCAACGAGCCGCC
CCGGCGCACCGCCGTGCCGGTGGCCGAGGCCATCCACGATACCGAGCGCCTGCTGCGCGTGACCCTGCCGCCGGCCATCG
AACTGCGGCTGCAGCTGGACCGCCACCTGCCCGCCATGCTGGCCGACGCCACCCAGGTGGAGCAGGCCCTGCTGAACCTC
TGCACGAACGCCATCCATGCCATCGGCGATGCGCGCGGCACGGTGTGCGTGGAGGCGTCGGCCGTGCAGCCCGATCACCG
CCTGTGCGAGCGCCTCGCGCTGCCGCACGGCGAATACGTGGCCATCAGCGTGGTGGACAACGGCCCCGGCATCGACCCGG
CCACGCAGCTGCGCATCTTCGAGCCGTTCTTCACCACCAAGCCCGTCGGCCAGGGCACCGGACTGGGCCTGGCCGTGGTG
CACGGCGTGATGCGCACCCACGGCGGCGCGGTGGACGTACAGAGCGCGCCCGGCGAGGGCAGCCGCTTCACGCTGTTTTT
CCCGGCGGCGGAGGCCGAACCCGAACCGGGGCCCGCTGCCGCCGCGCCAGCCGGCGATGCCGCACCGGCCGGCGCGGCCA
GCCCTGCCGCGCCTGCGGCGGGCGCACCCGACGAACGCCAGCGCCACGTGATGTACGTGGACGACGACCAGGCCCTGGTC
TTCCTCGTGCAGCGCCTGCTGCGCCGCCGCGGCTACCGCGTGACCGGCTTCACCGATCCGCGCGAGGCCGTGGTGGCGCT
GGGCGCGGACCCGCAGGCCTACGACCTGGTCGTGACCGACTACAACATGCCCGGCTACTGCGGCGTGGACCTGGTGCGCG
AGGCCAAGCGCATCCGCGCCGACCTGCCCGTGGCGCTCGCCTCGGGGCACGTGACGGCGGAGATCGAGCGCGAGGCGCTG
GCCGAAGGCGCGAGCGCGCTGATCCACAAGCCCAACGACGTGGATGAACTGTGCGCCACGGTGGACCGCCTGGTCCACGG
CGGGCCGGCGTGA

Upstream 100 bases:

>100_bases
GCCGGGCGGCTTCAGGGGCGTACACTGGCAGGCTCGCCCGCGGCACCGCCGCGTTCCGCACACCGCCCCGGCGTGAACCG
CCGGGCCGCCCGAGCCGCCC

Downstream 100 bases:

>100_bases
ACGCTGCCCTGCCGGCGCAGGCGCTGGCCGATGCCGATGCCGGCGCGCCCCCCGGCTGCCTGCATGCGGACGATGACCTG
CTGGTGCTGGCCAAGCCCTC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: WHR virA [H]

Number of amino acids: Translated: 750; Mature: 749

Protein sequence:

>750_residues
MSRPDLSFLLPPDPEDDRGTASGSGPAGPAGEPAGPPGDGGDNRRQPGRPEGPVAALIAELRAYQAELEVQNKVLRYSQA
AAESASERFETLFASVPLALMVLDEHDMVVQANSMAHRCFQPTESDRPLTSLMPFVSAADAARVRATFEQARDHGHGEAS
EVVFPIGDGDAGIIGDLYIARIEAPQADGAPEQWQFLCAVVDQGPLVAERRALQQSATALQERNVQLYASERRLEAVINS
ALDAIICVDQNQRITVFNPTAAALFQCATADALGSPLDRFLPDAVQALTFAQLATQAVLGEMVALTASGKELAVEVSVSF
ERHAEGETTTVFARDLTGRKKAEAHRNELEAQLRESHKMQAVGTMAGGIAHDFNNILSAILGNVELAKADCAAGSPVLES
LREIEKAGRRARDLVRQILTFSRNEPPRRTAVPVAEAIHDTERLLRVTLPPAIELRLQLDRHLPAMLADATQVEQALLNL
CTNAIHAIGDARGTVCVEASAVQPDHRLCERLALPHGEYVAISVVDNGPGIDPATQLRIFEPFFTTKPVGQGTGLGLAVV
HGVMRTHGGAVDVQSAPGEGSRFTLFFPAAEAEPEPGPAAAAPAGDAAPAGAASPAAPAAGAPDERQRHVMYVDDDQALV
FLVQRLLRRRGYRVTGFTDPREAVVALGADPQAYDLVVTDYNMPGYCGVDLVREAKRIRADLPVALASGHVTAEIEREAL
AEGASALIHKPNDVDELCATVDRLVHGGPA

Sequences:

>Translated_750_residues
MSRPDLSFLLPPDPEDDRGTASGSGPAGPAGEPAGPPGDGGDNRRQPGRPEGPVAALIAELRAYQAELEVQNKVLRYSQA
AAESASERFETLFASVPLALMVLDEHDMVVQANSMAHRCFQPTESDRPLTSLMPFVSAADAARVRATFEQARDHGHGEAS
EVVFPIGDGDAGIIGDLYIARIEAPQADGAPEQWQFLCAVVDQGPLVAERRALQQSATALQERNVQLYASERRLEAVINS
ALDAIICVDQNQRITVFNPTAAALFQCATADALGSPLDRFLPDAVQALTFAQLATQAVLGEMVALTASGKELAVEVSVSF
ERHAEGETTTVFARDLTGRKKAEAHRNELEAQLRESHKMQAVGTMAGGIAHDFNNILSAILGNVELAKADCAAGSPVLES
LREIEKAGRRARDLVRQILTFSRNEPPRRTAVPVAEAIHDTERLLRVTLPPAIELRLQLDRHLPAMLADATQVEQALLNL
CTNAIHAIGDARGTVCVEASAVQPDHRLCERLALPHGEYVAISVVDNGPGIDPATQLRIFEPFFTTKPVGQGTGLGLAVV
HGVMRTHGGAVDVQSAPGEGSRFTLFFPAAEAEPEPGPAAAAPAGDAAPAGAASPAAPAAGAPDERQRHVMYVDDDQALV
FLVQRLLRRRGYRVTGFTDPREAVVALGADPQAYDLVVTDYNMPGYCGVDLVREAKRIRADLPVALASGHVTAEIEREAL
AEGASALIHKPNDVDELCATVDRLVHGGPA
>Mature_749_residues
SRPDLSFLLPPDPEDDRGTASGSGPAGPAGEPAGPPGDGGDNRRQPGRPEGPVAALIAELRAYQAELEVQNKVLRYSQAA
AESASERFETLFASVPLALMVLDEHDMVVQANSMAHRCFQPTESDRPLTSLMPFVSAADAARVRATFEQARDHGHGEASE
VVFPIGDGDAGIIGDLYIARIEAPQADGAPEQWQFLCAVVDQGPLVAERRALQQSATALQERNVQLYASERRLEAVINSA
LDAIICVDQNQRITVFNPTAAALFQCATADALGSPLDRFLPDAVQALTFAQLATQAVLGEMVALTASGKELAVEVSVSFE
RHAEGETTTVFARDLTGRKKAEAHRNELEAQLRESHKMQAVGTMAGGIAHDFNNILSAILGNVELAKADCAAGSPVLESL
REIEKAGRRARDLVRQILTFSRNEPPRRTAVPVAEAIHDTERLLRVTLPPAIELRLQLDRHLPAMLADATQVEQALLNLC
TNAIHAIGDARGTVCVEASAVQPDHRLCERLALPHGEYVAISVVDNGPGIDPATQLRIFEPFFTTKPVGQGTGLGLAVVH
GVMRTHGGAVDVQSAPGEGSRFTLFFPAAEAEPEPGPAAAAPAGDAAPAGAASPAAPAAGAPDERQRHVMYVDDDQALVF
LVQRLLRRRGYRVTGFTDPREAVVALGADPQAYDLVVTDYNMPGYCGVDLVREAKRIRADLPVALASGHVTAEIEREALA
EGASALIHKPNDVDELCATVDRLVHGGPA

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=366, Percent_Identity=29.7814207650273, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=34.7826086956522, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1790300, Length=363, Percent_Identity=28.099173553719, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI48994928, Length=433, Percent_Identity=25.8660508083141, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI145693157, Length=360, Percent_Identity=24.7222222222222, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=424, Percent_Identity=24.0566037735849, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788713, Length=397, Percent_Identity=21.6624685138539, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=25, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787894, Length=241, Percent_Identity=26.5560165975104, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=27.1186440677966, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79767; Mature: 79635

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPDLSFLLPPDPEDDRGTASGSGPAGPAGEPAGPPGDGGDNRRQPGRPEGPVAALIAE
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LRAYQAELEVQNKVLRYSQAAAESASERFETLFASVPLALMVLDEHDMVVQANSMAHRCF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECHHHHHHC
QPTESDRPLTSLMPFVSAADAARVRATFEQARDHGHGEASEVVFPIGDGDAGIIGDLYIA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHCEEEE
RIEAPQADGAPEQWQFLCAVVDQGPLVAERRALQQSATALQERNVQLYASERRLEAVINS
EEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHH
ALDAIICVDQNQRITVFNPTAAALFQCATADALGSPLDRFLPDAVQALTFAQLATQAVLG
HHHEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
EMVALTASGKELAVEVSVSFERHAEGETTTVFARDLTGRKKAEAHRNELEAQLRESHKMQ
HHHHEEECCCEEEEEEEEEEHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
AVGTMAGGIAHDFNNILSAILGNVELAKADCAAGSPVLESLREIEKAGRRARDLVRQILT
HHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FSRNEPPRRTAVPVAEAIHDTERLLRVTLPPAIELRLQLDRHLPAMLADATQVEQALLNL
HCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHH
CTNAIHAIGDARGTVCVEASAVQPDHRLCERLALPHGEYVAISVVDNGPGIDPATQLRIF
HHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHEEEE
EPFFTTKPVGQGTGLGLAVVHGVMRTHGGAVDVQSAPGEGSRFTLFFPAAEAEPEPGPAA
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCC
AAPAGDAAPAGAASPAAPAAGAPDERQRHVMYVDDDQALVFLVQRLLRRRGYRVTGFTDP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCH
REAVVALGADPQAYDLVVTDYNMPGYCGVDLVREAKRIRADLPVALASGHVTAEIEREAL
HHHEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEECCCEEEHHHHHHH
AEGASALIHKPNDVDELCATVDRLVHGGPA
HCCCHHEEECCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SRPDLSFLLPPDPEDDRGTASGSGPAGPAGEPAGPPGDGGDNRRQPGRPEGPVAALIAE
CCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LRAYQAELEVQNKVLRYSQAAAESASERFETLFASVPLALMVLDEHDMVVQANSMAHRCF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECHHHHHHC
QPTESDRPLTSLMPFVSAADAARVRATFEQARDHGHGEASEVVFPIGDGDAGIIGDLYIA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHCEEEE
RIEAPQADGAPEQWQFLCAVVDQGPLVAERRALQQSATALQERNVQLYASERRLEAVINS
EEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHH
ALDAIICVDQNQRITVFNPTAAALFQCATADALGSPLDRFLPDAVQALTFAQLATQAVLG
HHHEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
EMVALTASGKELAVEVSVSFERHAEGETTTVFARDLTGRKKAEAHRNELEAQLRESHKMQ
HHHHEEECCCEEEEEEEEEEHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
AVGTMAGGIAHDFNNILSAILGNVELAKADCAAGSPVLESLREIEKAGRRARDLVRQILT
HHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FSRNEPPRRTAVPVAEAIHDTERLLRVTLPPAIELRLQLDRHLPAMLADATQVEQALLNL
HCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHH
CTNAIHAIGDARGTVCVEASAVQPDHRLCERLALPHGEYVAISVVDNGPGIDPATQLRIF
HHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHEEEE
EPFFTTKPVGQGTGLGLAVVHGVMRTHGGAVDVQSAPGEGSRFTLFFPAAEAEPEPGPAA
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCC
AAPAGDAAPAGAASPAAPAAGAPDERQRHVMYVDDDQALVFLVQRLLRRRGYRVTGFTDP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCH
REAVVALGADPQAYDLVVTDYNMPGYCGVDLVREAKRIRADLPVALASGHVTAEIEREAL
HHHEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEECCCEEEHHHHHHH
AEGASALIHKPNDVDELCATVDRLVHGGPA
HCCCHHEEECCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3595559 [H]