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The map label for this gene is ychM [C]

Identifier: 120611686

GI number: 120611686

Start: 3331838

End: 3333562

Strand: Direct

Name: ychM [C]

Synonym: Aave_3023

Alternate gene names: 120611686

Gene position: 3331838-3333562 (Clockwise)

Preceding gene: 120611683

Following gene: 120611687

Centisome position: 62.25

GC content: 70.14

Gene sequence:

>1725_bases
ATGTCCTCCGCCCCCTCCTCCGCGCCCTCCTCCGCGCCGCCGGAAGCCGGCACCTCCGGCCGCCTGCGCCTGCTCCAGCG
CTGGTTCCCTTTTCTCGCGTGGCCCCGGCCGGACGCCCAGTTGCTGCGGGGAGAGTTCTGGGCCGGCATGACCGTGGGGC
TGATGCTGGTGCCCCAGGGCGTGGCCTACGCGGCCCTGGCCGGCATGCCGCTGGTGACGGGGATCTACGCGTCGCTCGTG
CCCGCGTTGATCGCGGTGCTGTGGAGTTCATCCACCCGCCTGGGCGTGGGTCCCACGGCCCTCACCGCCCTGCTGATCGG
GGCCTCCCTCACCGGCATGGCGGAACCGGGCAGCGCCGAATGGGTGGCCCTGGCGGCCTGGATGGCCATCCTGTCGGGAC
TGGTGCAACTGCTGCTGGGCGCGGTGCGCTTCGGCTGGCTGCTCAACCTCGTCACGTCGCCCGTGCTCAACGGTTTCACC
CAGGCCGCCGCGCTGCTCATCCTGGCGTCGCAATTGCCCGCGCTGCTGGGGCTGCGCACCACCTGGCACGCGGTGGCCAC
CGCGCCGTCCATACACCACTTCGACGGCACGGCGGCGGCCTTCGGGCTCGGCAGCCTGGCCCTGCTGACCCTGGCGCGCC
GCTGGCGGCCCACCTTTCCCTCGGCCATCGTCATCGTCGGCATCGCGGCCCTGGTCAGCCGGGCCCTGGGCTACGCCGAC
CAGGACGGCGCGGTGGTGGGCCACCTGCCTTCCGGGCTGCCGCACTTCTACTGGCCGGGCTGGCTGGAGTGGGACCAGTT
CGGCCAGTTGCTGATGCCCGTGCTGGTGGTCACCCTCGTGAGCTTCCTGGAGACCGCCTCCTCCGCCAAGGTCGAGCACC
AGCAGGGCGGCACGCGCTGGAACGAGAACCAGGACCTCATCGCGCACGGTCTGGCGAAGATGGGGTCGGGTTTCTGCGGC
AGTTTCGCGACCAGCGCATCGTTCTCGCGCTCCGCGATCAACCTGTACGCGGGCGCGAAAAGCGGCTGGGCCACCCTGTT
CGCGCTGGCGCTGGTCCTGGCGGTGCTGCTGTGGCTCATGCCGGCGCTCTACCACGTGCCGCAGTCGGTGCTGGCGGCGG
TCGTGGTGGCGGCGGTCACCAGCCTCATCAGGCCGGCGGTGCTGCTGCGGCTCTGGCGCATTTCCCGGGTGGAGGCCCTC
ATCGGCGGGATGACGTTCTTCCTCACGCTCGCGACCGCGCCGCGCATGTACTGGGGAGTGCTGGCGGGACTGGTGCTGAA
CCTGAGCCATTTCCTCTACCAGCGGCTGCATCCGCGCATCATCGAAGTCGGGCTGCACCCGGACGGCAGCCTGCGCGACC
GCCACCTGTGGCAATTGCCGCCGCTCGCGCCCGGTCTTCTGGGTGTGCGGATGGACGCGGAACTGGATTTCGCGTCCGCT
GCTGCGCTGGAACAACGCATTTCGGAAGAACTTGCGGCACATTCCGAGGTGCGGCATATCTGCCTGTTCGCGCTGCCGAT
CAACCGCATCGACGTGACCGGCGTTGAGTGCTTCGGCCGGCTGCGGGCCCTGGCCCGCTCCCACGGTGGCGCACTGCACG
TGAGCGGCATGAAACTTCCTGTCGAGCAGGTGCTGCGCCGCGCGGGTTTGCTGGAGGGCCCGGGCCTGGTGCTCTACCGC
ACCGACGCCGAAGCCCTGCTGGCATTGCAACGTTTACCTTTGTAG

Upstream 100 bases:

>100_bases
TGGAGCGTCGGGAATATGACGAACTCTAGACTCGACCGTAGCGCGCCGCGGTCGGACAATGCCGAAGCTGGCGTAGGACG
CTTGAGGCGAGAATCCCCCC

Downstream 100 bases:

>100_bases
TTACCTATGGCGGGGCAGCCGCTGATACACTTCACGGACATTGTTTGTTGCATTTTGTGTCTGACTCCGCGACCCCCCCA
CTTGTGGACCTGCGCGACCT

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MSSAPSSAPSSAPPEAGTSGRLRLLQRWFPFLAWPRPDAQLLRGEFWAGMTVGLMLVPQGVAYAALAGMPLVTGIYASLV
PALIAVLWSSSTRLGVGPTALTALLIGASLTGMAEPGSAEWVALAAWMAILSGLVQLLLGAVRFGWLLNLVTSPVLNGFT
QAAALLILASQLPALLGLRTTWHAVATAPSIHHFDGTAAAFGLGSLALLTLARRWRPTFPSAIVIVGIAALVSRALGYAD
QDGAVVGHLPSGLPHFYWPGWLEWDQFGQLLMPVLVVTLVSFLETASSAKVEHQQGGTRWNENQDLIAHGLAKMGSGFCG
SFATSASFSRSAINLYAGAKSGWATLFALALVLAVLLWLMPALYHVPQSVLAAVVVAAVTSLIRPAVLLRLWRISRVEAL
IGGMTFFLTLATAPRMYWGVLAGLVLNLSHFLYQRLHPRIIEVGLHPDGSLRDRHLWQLPPLAPGLLGVRMDAELDFASA
AALEQRISEELAAHSEVRHICLFALPINRIDVTGVECFGRLRALARSHGGALHVSGMKLPVEQVLRRAGLLEGPGLVLYR
TDAEALLALQRLPL

Sequences:

>Translated_574_residues
MSSAPSSAPSSAPPEAGTSGRLRLLQRWFPFLAWPRPDAQLLRGEFWAGMTVGLMLVPQGVAYAALAGMPLVTGIYASLV
PALIAVLWSSSTRLGVGPTALTALLIGASLTGMAEPGSAEWVALAAWMAILSGLVQLLLGAVRFGWLLNLVTSPVLNGFT
QAAALLILASQLPALLGLRTTWHAVATAPSIHHFDGTAAAFGLGSLALLTLARRWRPTFPSAIVIVGIAALVSRALGYAD
QDGAVVGHLPSGLPHFYWPGWLEWDQFGQLLMPVLVVTLVSFLETASSAKVEHQQGGTRWNENQDLIAHGLAKMGSGFCG
SFATSASFSRSAINLYAGAKSGWATLFALALVLAVLLWLMPALYHVPQSVLAAVVVAAVTSLIRPAVLLRLWRISRVEAL
IGGMTFFLTLATAPRMYWGVLAGLVLNLSHFLYQRLHPRIIEVGLHPDGSLRDRHLWQLPPLAPGLLGVRMDAELDFASA
AALEQRISEELAAHSEVRHICLFALPINRIDVTGVECFGRLRALARSHGGALHVSGMKLPVEQVLRRAGLLEGPGLVLYR
TDAEALLALQRLPL
>Mature_573_residues
SSAPSSAPSSAPPEAGTSGRLRLLQRWFPFLAWPRPDAQLLRGEFWAGMTVGLMLVPQGVAYAALAGMPLVTGIYASLVP
ALIAVLWSSSTRLGVGPTALTALLIGASLTGMAEPGSAEWVALAAWMAILSGLVQLLLGAVRFGWLLNLVTSPVLNGFTQ
AAALLILASQLPALLGLRTTWHAVATAPSIHHFDGTAAAFGLGSLALLTLARRWRPTFPSAIVIVGIAALVSRALGYADQ
DGAVVGHLPSGLPHFYWPGWLEWDQFGQLLMPVLVVTLVSFLETASSAKVEHQQGGTRWNENQDLIAHGLAKMGSGFCGS
FATSASFSRSAINLYAGAKSGWATLFALALVLAVLLWLMPALYHVPQSVLAAVVVAAVTSLIRPAVLLRLWRISRVEALI
GGMTFFLTLATAPRMYWGVLAGLVLNLSHFLYQRLHPRIIEVGLHPDGSLRDRHLWQLPPLAPGLLGVRMDAELDFASAA
ALEQRISEELAAHSEVRHICLFALPINRIDVTGVECFGRLRALARSHGGALHVSGMKLPVEQVLRRAGLLEGPGLVLYRT
DAEALLALQRLPL

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI262206105, Length=614, Percent_Identity=29.9674267100977, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI262206075, Length=614, Percent_Identity=29.9674267100977, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI262206069, Length=614, Percent_Identity=29.9674267100977, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI262206063, Length=614, Percent_Identity=29.9674267100977, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI39752683, Length=492, Percent_Identity=25.2032520325203, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI45827800, Length=492, Percent_Identity=25.2032520325203, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI45827802, Length=453, Percent_Identity=26.0485651214128, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI4505697, Length=421, Percent_Identity=26.3657957244656, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI94721259, Length=500, Percent_Identity=26.8, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI94721253, Length=500, Percent_Identity=26.8, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI94721255, Length=500, Percent_Identity=26.8, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI94721257, Length=500, Percent_Identity=26.8, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4557535, Length=446, Percent_Identity=27.8026905829596, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI269784651, Length=380, Percent_Identity=26.3157894736842, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI47131207, Length=468, Percent_Identity=27.7777777777778, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI20336272, Length=468, Percent_Identity=27.7777777777778, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI100913030, Length=514, Percent_Identity=22.7626459143969, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI65506789, Length=377, Percent_Identity=29.973474801061, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI16306483, Length=449, Percent_Identity=24.0534521158129, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI20336282, Length=449, Percent_Identity=24.0534521158129, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI45827804, Length=263, Percent_Identity=25.8555133079848, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI217272867, Length=395, Percent_Identity=24.0506329113924, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI16418413, Length=412, Percent_Identity=24.0291262135922, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI16418457, Length=520, Percent_Identity=22.3076923076923, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI301601599, Length=520, Percent_Identity=22.3076923076923, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI87081859, Length=331, Percent_Identity=26.2839879154079, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17551690, Length=515, Percent_Identity=23.6893203883495, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17566848, Length=573, Percent_Identity=26.7015706806283, Blast_Score=138, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI86564196, Length=537, Percent_Identity=22.9050279329609, Blast_Score=129, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17562578, Length=508, Percent_Identity=24.8031496062992, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI86565215, Length=456, Percent_Identity=23.0263157894737, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI86564876, Length=470, Percent_Identity=21.9148936170213, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI86565213, Length=174, Percent_Identity=28.1609195402299, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319771, Length=438, Percent_Identity=26.9406392694064, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323121, Length=441, Percent_Identity=25.6235827664399, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6325260, Length=525, Percent_Identity=20.3809523809524, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24649801, Length=467, Percent_Identity=30.1927194860814, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI21358229, Length=474, Percent_Identity=27.8481012658228, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24651449, Length=506, Percent_Identity=24.5059288537549, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI19922482, Length=524, Percent_Identity=26.9083969465649, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI85815873, Length=457, Percent_Identity=28.2275711159737, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24663084, Length=458, Percent_Identity=29.2576419213974, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21357695, Length=458, Percent_Identity=29.2576419213974, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24647160, Length=471, Percent_Identity=26.1146496815287, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI21355087, Length=471, Percent_Identity=26.1146496815287, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI21358633, Length=435, Percent_Identity=26.8965517241379, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24666186, Length=447, Percent_Identity=23.7136465324385, Blast_Score=116, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 61252; Mature: 61120

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAPSSAPSSAPPEAGTSGRLRLLQRWFPFLAWPRPDAQLLRGEFWAGMTVGLMLVPQG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHCCC
VAYAALAGMPLVTGIYASLVPALIAVLWSSSTRLGVGPTALTALLIGASLTGMAEPGSAE
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCH
WVALAAWMAILSGLVQLLLGAVRFGWLLNLVTSPVLNGFTQAAALLILASQLPALLGLRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TWHAVATAPSIHHFDGTAAAFGLGSLALLTLARRWRPTFPSAIVIVGIAALVSRALGYAD
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
QDGAVVGHLPSGLPHFYWPGWLEWDQFGQLLMPVLVVTLVSFLETASSAKVEHQQGGTRW
CCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
NENQDLIAHGLAKMGSGFCGSFATSASFSRSAINLYAGAKSGWATLFALALVLAVLLWLM
CCCHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
PALYHVPQSVLAAVVVAAVTSLIRPAVLLRLWRISRVEALIGGMTFFLTLATAPRMYWGV
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LAGLVLNLSHFLYQRLHPRIIEVGLHPDGSLRDRHLWQLPPLAPGLLGVRMDAELDFASA
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHH
AALEQRISEELAAHSEVRHICLFALPINRIDVTGVECFGRLRALARSHGGALHVSGMKLP
HHHHHHHHHHHHHHHHHHHHHHEEECCCCEECHHHHHHHHHHHHHHCCCCEEEECCCCCC
VEQVLRRAGLLEGPGLVLYRTDAEALLALQRLPL
HHHHHHHCCCCCCCCEEEEECCHHHHHHHHHCCC
>Mature Secondary Structure 
SSAPSSAPSSAPPEAGTSGRLRLLQRWFPFLAWPRPDAQLLRGEFWAGMTVGLMLVPQG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHCCC
VAYAALAGMPLVTGIYASLVPALIAVLWSSSTRLGVGPTALTALLIGASLTGMAEPGSAE
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCH
WVALAAWMAILSGLVQLLLGAVRFGWLLNLVTSPVLNGFTQAAALLILASQLPALLGLRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TWHAVATAPSIHHFDGTAAAFGLGSLALLTLARRWRPTFPSAIVIVGIAALVSRALGYAD
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
QDGAVVGHLPSGLPHFYWPGWLEWDQFGQLLMPVLVVTLVSFLETASSAKVEHQQGGTRW
CCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
NENQDLIAHGLAKMGSGFCGSFATSASFSRSAINLYAGAKSGWATLFALALVLAVLLWLM
CCCHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
PALYHVPQSVLAAVVVAAVTSLIRPAVLLRLWRISRVEALIGGMTFFLTLATAPRMYWGV
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LAGLVLNLSHFLYQRLHPRIIEVGLHPDGSLRDRHLWQLPPLAPGLLGVRMDAELDFASA
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHH
AALEQRISEELAAHSEVRHICLFALPINRIDVTGVECFGRLRALARSHGGALHVSGMKLP
HHHHHHHHHHHHHHHHHHHHHHEEECCCCEECHHHHHHHHHHHHHHCCCCEEEECCCCCC
VEQVLRRAGLLEGPGLVLYRTDAEALLALQRLPL
HHHHHHHCCCCCCCCEEEEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]