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The map label for this gene is baeS [H]

Identifier: 120611664

GI number: 120611664

Start: 3308786

End: 3310462

Strand: Direct

Name: baeS [H]

Synonym: Aave_3001

Alternate gene names: 120611664

Gene position: 3308786-3310462 (Clockwise)

Preceding gene: 120611663

Following gene: 120611665

Centisome position: 61.81

GC content: 73.05

Gene sequence:

>1677_bases
ATGTTCCGATTGCGCCTGTCCCTGGCTTTCGCCACCCTGGTCGCGCTGGTGTGCGCGCAGGCGGCCTTCGTCTATTGGGG
CGCGAACCGCGTCTATAACTTCGCCCAGCACAGCCGCCTGGCGAGCGACATCCTCACCGAGCTGAACGAACTGGCGGCCA
ACAAGCAGCGGCTGCGGGTCTGGGCTTCGCAGCGGCTCATGAACGTGGATGCCTCGGTGGAGGTGCGCGACACCCTGCTG
TCCAGCATGCGCAGGAACGCCGCGCAGCTGCGGCAGTTGACGGAGCGCGACGGCGCCCTGTGGGCCGAGATGGCCGAGAA
CGAGGGGATCGCGATACCGCCCGAGGTGCGCGAGCTCGGCGCCGCAGCGCGGCTTTTCGACGACAACATCGCGGCCGTGC
AGGCCCGGCTGGTGCGCCTGCAGCCGCTGCAGCCGGGGTCGGAGTTCTCGTCCGTCTGGCAGGAGCTGAACCAGGTGTTC
GACATGGCCGACGGCCGCGACCTGCGCGAGCTGCTGAGCGGCGCCATCGCGCGCCAGCGCCGCGCCGTGCCGATCGCCCG
CGCCGATACGGAGCGCGGCCTGCGGGAGCTGCGCACGCAGGCCGTGGGCATGGCCCTCCTGACGCTGGCCACCGCCATCG
TGCTGGCGCAGCAGCTGACGCGCCGCCTGCAGCGCCCCCTGGACCGCCTGCTGGCGGGCACGCGCGCGCTGCAGGCCGGT
GCGCTGGACCACCGCGTGGAAACCGGTTCGCGGGACGAATTCGACCGGGTCGCCGAGCATTTCAACGCCATGGCCGCCGA
ACTCCAGGAACACCGCCGCGCGGCGGATGCGGCCCGCCGCCGCCTGGAGGATGCCGTCGAGGCACGCACGGCCGAACTGC
GCACCGCCCACGAGGCGCTGCAGCGCAACGACGAGCGGCGCCGGCAACTCTTCGCCGACCTGAGCCATGAGTTGCGCACC
CCCGCCACGGCCATCCGCGGCGAGGCGGAGATCGCGCTGCGCGGCGGCGTGCGACCGGCGGAGGAATACCGGCAGACCCT
GGAGCGCATCGTCGGCGCCGTGGAGCAGCTCACCGGGACCGTGGACGACCTGATGCTCGTGGCACGCACGGAAGCCGATC
CGCTCGCCATGCGGCCCGGCCCGGTCGCGCTGCACGGATTGCTGCGCGATGCGGCCGAACAGGCCGAGGCGCTGTGCGCC
CTGTACGGGGTGCATCTGCGGCTGCAGGAGCCGGCCGCATGGCCCGGCGGGCAGGCGGGCCCCACGCTGCACGCGGATGC
CGACCGCCTGCGCCAGGCCCTGATGATCGTTCTGGACAACGCCGCGCGCTATTCCCATGCCGGCGGCACCGTCCACCTCG
GATGGCACGCGGAGAACGCAGGCGGCGTCGCCATCGAGGTGCGCGACGAAGGCATCGGCATCGACGCGGAGGAATTGCCG
CAGGTGTTCGACCGGTTCATGCGCGGCAGCCGGGCCCGGGCGCACCGCGCCGACGGCACGGGCATCGGCCTGTCCATCGC
CCGCGCCATCGTGGAAGCACACGGCGGATCCATGTCCATCGGGCCCGTGCACCCCCGCGGCACCCTCGTCGGCATCCACC
TGCCGGCCGCATGCGTGGCCGGCGTGCACGCGTCCCCGGCGCCTGCGAGCGCCGCACGGGCGGAGGACGGCCGATGA

Upstream 100 bases:

>100_bases
TCGCGCAGGAGCACCTGTCGGGCTGGGATACGGGGGCACCGGGCGGAGCGGCAGCGCCCGGCCTGGCCCGCTGAGCGAGC
CGCACCGCGAGGCCCGCGCC

Downstream 100 bases:

>100_bases
GCACCGCGCAGATCCTGGTCGTGGAGGACGATCCCCGCGTTGCCGATTTCCTGCAGCGTGGCCTGCGCGCGGAAGGCTAC
GGCGTGCAGATGGCGCGCAC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MFRLRLSLAFATLVALVCAQAAFVYWGANRVYNFAQHSRLASDILTELNELAANKQRLRVWASQRLMNVDASVEVRDTLL
SSMRRNAAQLRQLTERDGALWAEMAENEGIAIPPEVRELGAAARLFDDNIAAVQARLVRLQPLQPGSEFSSVWQELNQVF
DMADGRDLRELLSGAIARQRRAVPIARADTERGLRELRTQAVGMALLTLATAIVLAQQLTRRLQRPLDRLLAGTRALQAG
ALDHRVETGSRDEFDRVAEHFNAMAAELQEHRRAADAARRRLEDAVEARTAELRTAHEALQRNDERRRQLFADLSHELRT
PATAIRGEAEIALRGGVRPAEEYRQTLERIVGAVEQLTGTVDDLMLVARTEADPLAMRPGPVALHGLLRDAAEQAEALCA
LYGVHLRLQEPAAWPGGQAGPTLHADADRLRQALMIVLDNAARYSHAGGTVHLGWHAENAGGVAIEVRDEGIGIDAEELP
QVFDRFMRGSRARAHRADGTGIGLSIARAIVEAHGGSMSIGPVHPRGTLVGIHLPAACVAGVHASPAPASAARAEDGR

Sequences:

>Translated_558_residues
MFRLRLSLAFATLVALVCAQAAFVYWGANRVYNFAQHSRLASDILTELNELAANKQRLRVWASQRLMNVDASVEVRDTLL
SSMRRNAAQLRQLTERDGALWAEMAENEGIAIPPEVRELGAAARLFDDNIAAVQARLVRLQPLQPGSEFSSVWQELNQVF
DMADGRDLRELLSGAIARQRRAVPIARADTERGLRELRTQAVGMALLTLATAIVLAQQLTRRLQRPLDRLLAGTRALQAG
ALDHRVETGSRDEFDRVAEHFNAMAAELQEHRRAADAARRRLEDAVEARTAELRTAHEALQRNDERRRQLFADLSHELRT
PATAIRGEAEIALRGGVRPAEEYRQTLERIVGAVEQLTGTVDDLMLVARTEADPLAMRPGPVALHGLLRDAAEQAEALCA
LYGVHLRLQEPAAWPGGQAGPTLHADADRLRQALMIVLDNAARYSHAGGTVHLGWHAENAGGVAIEVRDEGIGIDAEELP
QVFDRFMRGSRARAHRADGTGIGLSIARAIVEAHGGSMSIGPVHPRGTLVGIHLPAACVAGVHASPAPASAARAEDGR
>Mature_558_residues
MFRLRLSLAFATLVALVCAQAAFVYWGANRVYNFAQHSRLASDILTELNELAANKQRLRVWASQRLMNVDASVEVRDTLL
SSMRRNAAQLRQLTERDGALWAEMAENEGIAIPPEVRELGAAARLFDDNIAAVQARLVRLQPLQPGSEFSSVWQELNQVF
DMADGRDLRELLSGAIARQRRAVPIARADTERGLRELRTQAVGMALLTLATAIVLAQQLTRRLQRPLDRLLAGTRALQAG
ALDHRVETGSRDEFDRVAEHFNAMAAELQEHRRAADAARRRLEDAVEARTAELRTAHEALQRNDERRRQLFADLSHELRT
PATAIRGEAEIALRGGVRPAEEYRQTLERIVGAVEQLTGTVDDLMLVARTEADPLAMRPGPVALHGLLRDAAEQAEALCA
LYGVHLRLQEPAAWPGGQAGPTLHADADRLRQALMIVLDNAARYSHAGGTVHLGWHAENAGGVAIEVRDEGIGIDAEELP
QVFDRFMRGSRARAHRADGTGIGLSIARAIVEAHGGSMSIGPVHPRGTLVGIHLPAACVAGVHASPAPASAARAEDGR

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=315, Percent_Identity=30.1587301587302, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1789149, Length=351, Percent_Identity=25.3561253561254, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788279, Length=225, Percent_Identity=27.1111111111111, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=31.1688311688312, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=30.9417040358744, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1786600, Length=239, Percent_Identity=27.1966527196653, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=216, Percent_Identity=28.2407407407407, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI48994928, Length=252, Percent_Identity=25.7936507936508, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87081816, Length=364, Percent_Identity=26.0989010989011, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788713, Length=234, Percent_Identity=25.2136752136752, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1788549, Length=228, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=23.4126984126984, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=26.6393442622951, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789403, Length=216, Percent_Identity=27.3148148148148, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790551, Length=328, Percent_Identity=24.0853658536585, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789808, Length=216, Percent_Identity=31.9444444444444, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60888; Mature: 60888

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRLRLSLAFATLVALVCAQAAFVYWGANRVYNFAQHSRLASDILTELNELAANKQRLRV
CEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WASQRLMNVDASVEVRDTLLSSMRRNAAQLRQLTERDGALWAEMAENEGIAIPPEVRELG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHH
AAARLFDDNIAAVQARLVRLQPLQPGSEFSSVWQELNQVFDMADGRDLRELLSGAIARQR
HHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
RAVPIARADTERGLRELRTQAVGMALLTLATAIVLAQQLTRRLQRPLDRLLAGTRALQAG
CCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ALDHRVETGSRDEFDRVAEHFNAMAAELQEHRRAADAARRRLEDAVEARTAELRTAHEAL
CHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRNDERRRQLFADLSHELRTPATAIRGEAEIALRGGVRPAEEYRQTLERIVGAVEQLTGT
HCCHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
VDDLMLVARTEADPLAMRPGPVALHGLLRDAAEQAEALCALYGVHLRLQEPAAWPGGQAG
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
PTLHADADRLRQALMIVLDNAARYSHAGGTVHLGWHAENAGGVAIEVRDEGIGIDAEELP
CCCCCCHHHHHHHHHHHHHCCHHHCCCCCEEEEEEEECCCCCEEEEEECCCCCCCHHHHH
QVFDRFMRGSRARAHRADGTGIGLSIARAIVEAHGGSMSIGPVHPRGTLVGIHLPAACVA
HHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHH
GVHASPAPASAARAEDGR
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFRLRLSLAFATLVALVCAQAAFVYWGANRVYNFAQHSRLASDILTELNELAANKQRLRV
CEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WASQRLMNVDASVEVRDTLLSSMRRNAAQLRQLTERDGALWAEMAENEGIAIPPEVRELG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHH
AAARLFDDNIAAVQARLVRLQPLQPGSEFSSVWQELNQVFDMADGRDLRELLSGAIARQR
HHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
RAVPIARADTERGLRELRTQAVGMALLTLATAIVLAQQLTRRLQRPLDRLLAGTRALQAG
CCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ALDHRVETGSRDEFDRVAEHFNAMAAELQEHRRAADAARRRLEDAVEARTAELRTAHEAL
CHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRNDERRRQLFADLSHELRTPATAIRGEAEIALRGGVRPAEEYRQTLERIVGAVEQLTGT
HCCHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
VDDLMLVARTEADPLAMRPGPVALHGLLRDAAEQAEALCALYGVHLRLQEPAAWPGGQAG
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
PTLHADADRLRQALMIVLDNAARYSHAGGTVHLGWHAENAGGVAIEVRDEGIGIDAEELP
CCCCCCHHHHHHHHHHHHHCCHHHCCCCCEEEEEEEECCCCCEEEEEECCCCCCCHHHHH
QVFDRFMRGSRARAHRADGTGIGLSIARAIVEAHGGSMSIGPVHPRGTLVGIHLPAACVA
HHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHH
GVHASPAPASAARAEDGR
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]