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The map label for this gene is zraS [C]

Identifier: 120611639

GI number: 120611639

Start: 3266553

End: 3269222

Strand: Direct

Name: zraS [C]

Synonym: Aave_2976

Alternate gene names: 120611639

Gene position: 3266553-3269222 (Clockwise)

Preceding gene: 120611638

Following gene: 120611640

Centisome position: 61.03

GC content: 70.0

Gene sequence:

>2670_bases
ATGACGATCCCACCGACCCCGCCCGCCGAGCGCCATGCCGACATCTTCATCGGCCAGAGCGAGATGGCACGGCGCATGCG
CCAGCACGACTGGGAAGCGACGCCGCTCGGGCCGCCCGAACGCTGGCCCCAGGGGCTCAAGGCCGCGCTGCGCATCCTGC
TGACCTCCCGCTTCGAAATGTGGGTGGGCTGGGGCCCGGACATCGCTTTCTTCTACAACGACGCCTACCGCCCCACGCTG
GGCACCAAGCATCCCCAAGCGCTGGGCCGGCCCACTTCGCAGATCTGGGCAGAAATCTGGGACGACGTGAAGGACCGGAT
GCACGCGGTGTACCAGCGTGGCGAATCCACCTGGGATTCCTCCCTGATGCTGCTCATCGACCGTGCAGGAACGGGCACCC
TCGAGGAGACCTACCACACCTTCTCGTACAGCCCGCTGCTGGACGACGACGGGCGCGTGAACGGCCTGTTCTGCGCGGTG
TCCGAAGAGACGCGCCGCGTCATCAGCGAGCGGCGCCTGGCGGTGCTGCACGAACTGAGCGCGGCGATGTCGCTGGGCGG
CACCCGCCAGCAGGTCGTGGACGGCGCCTGCGCCACCCTGGCGAACGCGCAGCACGACCTGCCCTTCTCGCTGATCTATC
TCCACGATGCCCACGGCACGGCGCGGCTGGCCTGCAATGCCGGCGTGCCCTCGGGCCACCGGCTGGCGCCGCGCGAAATC
GCGCCCGGCGCGCCGTGGCCCTGGCGCCTGGACCGGCTCGCGGCCGGCGAGGCCGCATTCGCAGTCCCACTGGAGCCGGC
GGCCGACACGCCCACCGGCGCGTGGCAGGTTCCGCCACACACCGCGTTCGTGGTGGCGCTGCCCCCGCAAGGGGACGCCC
GGTCCGCGGGCTTCCTCGTGTGCGGTGCGAATCCGCACCGCCCCGGGGACGACGCCGAGACCCGGTCGTTCGTGCAACTG
CTCGCCGGGCAGGTGGCGCCGGCCGTCGCGCAGGCCGAGGCGCTGGAATCCCGCACGGCCGAGCGCGACCGCCTGCGCGA
ACTGTTCAGCAAGGCGCCGGGCTTCATGTGCGTGCTGCGCGGGCCCGACCACGTTTTCGAGTTCGTCAACGATTCATACC
AGCAGCTCATCGGCCGCAGGGACCTCGAAGGCAAGTCCATCCGCGACGCCATGCCGGAACTGCAGGGCCAGGGCATCCAC
GAACTGCTCGACGAGGTGTACCGCACCGGCAGGCCCTACATCGGCAAGAACCTCAAGGTCATGCTGCAGCGCGATCCCGG
CGGTCCGCTGACCGAGCACTACCTGAACTTCATCTACCAGCCCACGCTGGACGGCACGGGGGCGGTGAACGGCATCTTCG
CCGAAGGCTACGACGTGACCGACCAGCGCGTCGCGGAACAGGAACTGCGCGCCCTCAACAGCCACCTGGAAAGCCGGGTG
GCCGAGCGCACCCGCGACCTGGAGGACGCTCTGGCGCGCCTCACCGCGGAATCCCGCGAGCGCGAGGCCGCCCAGGAGGC
GCTGCGGCAGTCGCAGAAGATGGAAGCCGTAGGCCAGCTCACCGGCGGTCTCGCGCATGATTTCAACAATCTGCTGGCCA
CCATCAGCGGCAGCCTCGAGTTGCTCAACCGGCGCGTGGCACAGGGGCGCTTCGACGACCTCGCCCGCTACGTGGCGGTC
GGCCAGGGGGCCGCGCGGCGCGCCGCCTCCCTCACCCACCGCATGCTGGCCTTCTCGCGGCGGCAGACGCTCGACCCCAA
GCCCACCGATGTGAACCGTCTGGTGCGCGGCATGGAGGAGCTCATCCGGCGCACCATCGGCCCCGAGACCGAACTGGAGG
TCGTGAACGCGGTGGGCCTGTGGACCACCCATGTGGACCCCCACCAGCTCGAAAGCGCTCTCCTGAACCTGTGCATCAAT
TCCCGCGATGCCATGCCCGGCGGCGGCCGGCTCACCATAGAGACCGCCAATGCCTGGATGGACGAGCGCGCCGGACGCGA
GCGCGACCTTCCGCCGGGCCAGTACGTGTCGCTGTGCGTGACCGATACCGGCACGGGCATGGCACCCGAGGTGATGCGCC
GGATCTTCGAGCCCTTCTTCACCACCAAGCCGATCGGCATGGGCACGGGCCTGGGCCTTTCGATGGTGTACGGGTTCGCC
CGGCAATCCGGCGGGCAGGTGCGCGCTTATTCCGAGCCCGGCATGGGCACGACGATGTGCATCTACCTGCCCCGCCACGA
AGCGCCGCCCGAGGATTCCGACCTGCCGGCCCTGCAGCCCGCGGAGGCCGGCGAGGGATCGGGCACGGTGCTCGTGGTGG
ACGACGAGCCCAGCGTGCGCGCCCTGGTGGTGGAGGTGCTGCACGAAATGGGCTACCAGACCATCGAGGCGCACGACGGC
CCCTCCGCACTGCAGGTGCTGCAATCGCGCACCCACCTGGATCTGCTGATCACCGACGTCGGCCTGCCCGGCGGCATGAA
CGGGCGCCAGCTCGCCGATGGCGGGCGCCTCACGCGGCCCGACCTGCAGATCCTCTTCATCACCGGCTATGCCGAGAACG
CGGCCGTGGGCAACGGCCATCTGGAGCGGGGCATGCACGTGCTGACCAAGCCCTTCACGCTCGATGCGCTGGCCCACCGC
GTGCGCACCCTCATCCCGCAACCGTCATGA

Upstream 100 bases:

>100_bases
CGCACACCTGGGCAAGCCCCTGCAGCCCCATGCCCTGATGGCCACGATCGCGCGCCTGATGGCCGCCCGCCCGGCCTAGA
CACCGACGTCCCCTGACGCC

Downstream 100 bases:

>100_bases
GGCCTGCCGTGCTCCGTCCTCCTGGCCCGCCCGGCGACGCCATCCACGCGCAGGGCGGGCCCGCGGCCGACTGCCTGGGC
GCCCTGCGGGACGCCACGCG

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 889; Mature: 888

Protein sequence:

>889_residues
MTIPPTPPAERHADIFIGQSEMARRMRQHDWEATPLGPPERWPQGLKAALRILLTSRFEMWVGWGPDIAFFYNDAYRPTL
GTKHPQALGRPTSQIWAEIWDDVKDRMHAVYQRGESTWDSSLMLLIDRAGTGTLEETYHTFSYSPLLDDDGRVNGLFCAV
SEETRRVISERRLAVLHELSAAMSLGGTRQQVVDGACATLANAQHDLPFSLIYLHDAHGTARLACNAGVPSGHRLAPREI
APGAPWPWRLDRLAAGEAAFAVPLEPAADTPTGAWQVPPHTAFVVALPPQGDARSAGFLVCGANPHRPGDDAETRSFVQL
LAGQVAPAVAQAEALESRTAERDRLRELFSKAPGFMCVLRGPDHVFEFVNDSYQQLIGRRDLEGKSIRDAMPELQGQGIH
ELLDEVYRTGRPYIGKNLKVMLQRDPGGPLTEHYLNFIYQPTLDGTGAVNGIFAEGYDVTDQRVAEQELRALNSHLESRV
AERTRDLEDALARLTAESREREAAQEALRQSQKMEAVGQLTGGLAHDFNNLLATISGSLELLNRRVAQGRFDDLARYVAV
GQGAARRAASLTHRMLAFSRRQTLDPKPTDVNRLVRGMEELIRRTIGPETELEVVNAVGLWTTHVDPHQLESALLNLCIN
SRDAMPGGGRLTIETANAWMDERAGRERDLPPGQYVSLCVTDTGTGMAPEVMRRIFEPFFTTKPIGMGTGLGLSMVYGFA
RQSGGQVRAYSEPGMGTTMCIYLPRHEAPPEDSDLPALQPAEAGEGSGTVLVVDDEPSVRALVVEVLHEMGYQTIEAHDG
PSALQVLQSRTHLDLLITDVGLPGGMNGRQLADGGRLTRPDLQILFITGYAENAAVGNGHLERGMHVLTKPFTLDALAHR
VRTLIPQPS

Sequences:

>Translated_889_residues
MTIPPTPPAERHADIFIGQSEMARRMRQHDWEATPLGPPERWPQGLKAALRILLTSRFEMWVGWGPDIAFFYNDAYRPTL
GTKHPQALGRPTSQIWAEIWDDVKDRMHAVYQRGESTWDSSLMLLIDRAGTGTLEETYHTFSYSPLLDDDGRVNGLFCAV
SEETRRVISERRLAVLHELSAAMSLGGTRQQVVDGACATLANAQHDLPFSLIYLHDAHGTARLACNAGVPSGHRLAPREI
APGAPWPWRLDRLAAGEAAFAVPLEPAADTPTGAWQVPPHTAFVVALPPQGDARSAGFLVCGANPHRPGDDAETRSFVQL
LAGQVAPAVAQAEALESRTAERDRLRELFSKAPGFMCVLRGPDHVFEFVNDSYQQLIGRRDLEGKSIRDAMPELQGQGIH
ELLDEVYRTGRPYIGKNLKVMLQRDPGGPLTEHYLNFIYQPTLDGTGAVNGIFAEGYDVTDQRVAEQELRALNSHLESRV
AERTRDLEDALARLTAESREREAAQEALRQSQKMEAVGQLTGGLAHDFNNLLATISGSLELLNRRVAQGRFDDLARYVAV
GQGAARRAASLTHRMLAFSRRQTLDPKPTDVNRLVRGMEELIRRTIGPETELEVVNAVGLWTTHVDPHQLESALLNLCIN
SRDAMPGGGRLTIETANAWMDERAGRERDLPPGQYVSLCVTDTGTGMAPEVMRRIFEPFFTTKPIGMGTGLGLSMVYGFA
RQSGGQVRAYSEPGMGTTMCIYLPRHEAPPEDSDLPALQPAEAGEGSGTVLVVDDEPSVRALVVEVLHEMGYQTIEAHDG
PSALQVLQSRTHLDLLITDVGLPGGMNGRQLADGGRLTRPDLQILFITGYAENAAVGNGHLERGMHVLTKPFTLDALAHR
VRTLIPQPS
>Mature_888_residues
TIPPTPPAERHADIFIGQSEMARRMRQHDWEATPLGPPERWPQGLKAALRILLTSRFEMWVGWGPDIAFFYNDAYRPTLG
TKHPQALGRPTSQIWAEIWDDVKDRMHAVYQRGESTWDSSLMLLIDRAGTGTLEETYHTFSYSPLLDDDGRVNGLFCAVS
EETRRVISERRLAVLHELSAAMSLGGTRQQVVDGACATLANAQHDLPFSLIYLHDAHGTARLACNAGVPSGHRLAPREIA
PGAPWPWRLDRLAAGEAAFAVPLEPAADTPTGAWQVPPHTAFVVALPPQGDARSAGFLVCGANPHRPGDDAETRSFVQLL
AGQVAPAVAQAEALESRTAERDRLRELFSKAPGFMCVLRGPDHVFEFVNDSYQQLIGRRDLEGKSIRDAMPELQGQGIHE
LLDEVYRTGRPYIGKNLKVMLQRDPGGPLTEHYLNFIYQPTLDGTGAVNGIFAEGYDVTDQRVAEQELRALNSHLESRVA
ERTRDLEDALARLTAESREREAAQEALRQSQKMEAVGQLTGGLAHDFNNLLATISGSLELLNRRVAQGRFDDLARYVAVG
QGAARRAASLTHRMLAFSRRQTLDPKPTDVNRLVRGMEELIRRTIGPETELEVVNAVGLWTTHVDPHQLESALLNLCINS
RDAMPGGGRLTIETANAWMDERAGRERDLPPGQYVSLCVTDTGTGMAPEVMRRIFEPFFTTKPIGMGTGLGLSMVYGFAR
QSGGQVRAYSEPGMGTTMCIYLPRHEAPPEDSDLPALQPAEAGEGSGTVLVVDDEPSVRALVVEVLHEMGYQTIEAHDGP
SALQVLQSRTHLDLLITDVGLPGGMNGRQLADGGRLTRPDLQILFITGYAENAAVGNGHLERGMHVLTKPFTLDALAHRV
RTLIPQPS

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=29.0322580645161, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788713, Length=426, Percent_Identity=26.056338028169, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=26.8292682926829, Blast_Score=90, Evalue=7e-19,
Organism=Escherichia coli, GI145693157, Length=155, Percent_Identity=36.1290322580645, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=280, Percent_Identity=27.1428571428571, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=156, Percent_Identity=29.4871794871795, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 97578; Mature: 97446

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPPTPPAERHADIFIGQSEMARRMRQHDWEATPLGPPERWPQGLKAALRILLTSRFEM
CCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHE
WVGWGPDIAFFYNDAYRPTLGTKHPQALGRPTSQIWAEIWDDVKDRMHAVYQRGESTWDS
EECCCCCEEEEECCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SLMLLIDRAGTGTLEETYHTFSYSPLLDDDGRVNGLFCAVSEETRRVISERRLAVLHELS
CEEEEEECCCCCCHHHHHHHEECCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHH
AAMSLGGTRQQVVDGACATLANAQHDLPFSLIYLHDAHGTARLACNAGVPSGHRLAPREI
HHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCHHC
APGAPWPWRLDRLAAGEAAFAVPLEPAADTPTGAWQVPPHTAFVVALPPQGDARSAGFLV
CCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCEECCCCCEEEEEECCCCCCCCCCEEE
CGANPHRPGDDAETRSFVQLLAGQVAPAVAQAEALESRTAERDRLRELFSKAPGFMCVLR
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GPDHVFEFVNDSYQQLIGRRDLEGKSIRDAMPELQGQGIHELLDEVYRTGRPYIGKNLKV
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEE
MLQRDPGGPLTEHYLNFIYQPTLDGTGAVNGIFAEGYDVTDQRVAEQELRALNSHLESRV
EEEECCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHH
AERTRDLEDALARLTAESREREAAQEALRQSQKMEAVGQLTGGLAHDFNNLLATISGSLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLNRRVAQGRFDDLARYVAVGQGAARRAASLTHRMLAFSRRQTLDPKPTDVNRLVRGMEE
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LIRRTIGPETELEVVNAVGLWTTHVDPHQLESALLNLCINSRDAMPGGGRLTIETANAWM
HHHHHCCCCCHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHH
DERAGRERDLPPGQYVSLCVTDTGTGMAPEVMRRIFEPFFTTKPIGMGTGLGLSMVYGFA
HHHCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
RQSGGQVRAYSEPGMGTTMCIYLPRHEAPPEDSDLPALQPAEAGEGSGTVLVVDDEPSVR
HCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHH
ALVVEVLHEMGYQTIEAHDGPSALQVLQSRTHLDLLITDVGLPGGMNGRQLADGGRLTRP
HHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCEECCCCCCCCC
DLQILFITGYAENAAVGNGHLERGMHVLTKPFTLDALAHRVRTLIPQPS
CEEEEEEECCCCCCCCCCCHHHHCHHHHCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TIPPTPPAERHADIFIGQSEMARRMRQHDWEATPLGPPERWPQGLKAALRILLTSRFEM
CCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHE
WVGWGPDIAFFYNDAYRPTLGTKHPQALGRPTSQIWAEIWDDVKDRMHAVYQRGESTWDS
EECCCCCEEEEECCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SLMLLIDRAGTGTLEETYHTFSYSPLLDDDGRVNGLFCAVSEETRRVISERRLAVLHELS
CEEEEEECCCCCCHHHHHHHEECCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHH
AAMSLGGTRQQVVDGACATLANAQHDLPFSLIYLHDAHGTARLACNAGVPSGHRLAPREI
HHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCHHC
APGAPWPWRLDRLAAGEAAFAVPLEPAADTPTGAWQVPPHTAFVVALPPQGDARSAGFLV
CCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCEECCCCCEEEEEECCCCCCCCCCEEE
CGANPHRPGDDAETRSFVQLLAGQVAPAVAQAEALESRTAERDRLRELFSKAPGFMCVLR
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GPDHVFEFVNDSYQQLIGRRDLEGKSIRDAMPELQGQGIHELLDEVYRTGRPYIGKNLKV
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEE
MLQRDPGGPLTEHYLNFIYQPTLDGTGAVNGIFAEGYDVTDQRVAEQELRALNSHLESRV
EEEECCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHH
AERTRDLEDALARLTAESREREAAQEALRQSQKMEAVGQLTGGLAHDFNNLLATISGSLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLNRRVAQGRFDDLARYVAVGQGAARRAASLTHRMLAFSRRQTLDPKPTDVNRLVRGMEE
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LIRRTIGPETELEVVNAVGLWTTHVDPHQLESALLNLCINSRDAMPGGGRLTIETANAWM
HHHHHCCCCCHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHH
DERAGRERDLPPGQYVSLCVTDTGTGMAPEVMRRIFEPFFTTKPIGMGTGLGLSMVYGFA
HHHCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
RQSGGQVRAYSEPGMGTTMCIYLPRHEAPPEDSDLPALQPAEAGEGSGTVLVVDDEPSVR
HCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHH
ALVVEVLHEMGYQTIEAHDGPSALQVLQSRTHLDLLITDVGLPGGMNGRQLADGGRLTRP
HHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCEECCCCCCCCC
DLQILFITGYAENAAVGNGHLERGMHVLTKPFTLDALAHRVRTLIPQPS
CEEEEEEECCCCCCCCCCCHHHHCHHHHCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA