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The map label for this gene is msrB [H]

Identifier: 120611611

GI number: 120611611

Start: 3239136

End: 3239549

Strand: Direct

Name: msrB [H]

Synonym: Aave_2948

Alternate gene names: 120611611

Gene position: 3239136-3239549 (Clockwise)

Preceding gene: 120611610

Following gene: 120611612

Centisome position: 60.51

GC content: 69.08

Gene sequence:

>414_bases
ATGACCTACCCCATCCAGAAGACCGATGCCGAGTGGCAGGCACTGCTGCAGGACAAGGGCGCCGAACCCGCCGCCTGGCA
GGTGACGCGGCACGCCGCCACCGAGCGGCCCTTCACCGGAAAGTACGAAGCCCACTGGGCCGACGGCAGCTACCATTGCG
TCTGCTGCGGCGCGAAGCTGTTCGATTCGGACACCAAGTTCGACGCCGGCTGCGGCTGGCCCAGCTTCTCCCTGGCGGTG
CCCGGCGCCATCCGCGAAATCGTGGACCGCAGCCACGGCATGGTGCGCACCGAGACGGTGTGTGCACAATGCGGGGCCCA
TCTCGGCCATGTGTTCGAGGACGGGCCCGCGCCCACCGGGCTGCGCTACTGCATGAACTCCGCCTCGCTGGACTTCGAGC
CGGGCGGCGCCTGA

Upstream 100 bases:

>100_bases
AGGCCGTGCTGGCCCGGCCTTTCGACGAACATCCCGCGCATGCCGAGTGGGCGGGCTTCCCGCCCGACTGGGCCTCTTCC
ATCGAAATCAGCTGTTCATC

Downstream 100 bases:

>100_bases
CGCAGCGACGGCGCGCGGCCCACGCATGACGAGACCGGAAACCGCCCTGCCCCATCCATGAAACTGCTGATCGACTTTTT
CCCCATCATCCTGTTCTTCG

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MTYPIQKTDAEWQALLQDKGAEPAAWQVTRHAATERPFTGKYEAHWADGSYHCVCCGAKLFDSDTKFDAGCGWPSFSLAV
PGAIREIVDRSHGMVRTETVCAQCGAHLGHVFEDGPAPTGLRYCMNSASLDFEPGGA

Sequences:

>Translated_137_residues
MTYPIQKTDAEWQALLQDKGAEPAAWQVTRHAATERPFTGKYEAHWADGSYHCVCCGAKLFDSDTKFDAGCGWPSFSLAV
PGAIREIVDRSHGMVRTETVCAQCGAHLGHVFEDGPAPTGLRYCMNSASLDFEPGGA
>Mature_136_residues
TYPIQKTDAEWQALLQDKGAEPAAWQVTRHAATERPFTGKYEAHWADGSYHCVCCGAKLFDSDTKFDAGCGWPSFSLAVP
GAIREIVDRSHGMVRTETVCAQCGAHLGHVFEDGPAPTGLRYCMNSASLDFEPGGA

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=117, Percent_Identity=53.8461538461538, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI301336162, Length=117, Percent_Identity=53.8461538461538, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI73089054, Length=117, Percent_Identity=53.8461538461538, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI37620216, Length=117, Percent_Identity=53.8461538461538, Blast_Score=128, Evalue=1e-30,
Organism=Homo sapiens, GI117606353, Length=135, Percent_Identity=47.4074074074074, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1788077, Length=118, Percent_Identity=55.0847457627119, Blast_Score=129, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17553450, Length=133, Percent_Identity=49.6240601503759, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI115532676, Length=133, Percent_Identity=49.6240601503759, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6319816, Length=135, Percent_Identity=42.962962962963, Blast_Score=97, Evalue=7e-22,
Organism=Drosophila melanogaster, GI221378662, Length=123, Percent_Identity=47.9674796747967, Blast_Score=133, Evalue=3e-32,
Organism=Drosophila melanogaster, GI221378664, Length=116, Percent_Identity=51.7241379310345, Blast_Score=129, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24645804, Length=127, Percent_Identity=46.4566929133858, Blast_Score=128, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24645801, Length=127, Percent_Identity=46.4566929133858, Blast_Score=128, Evalue=9e-31,
Organism=Drosophila melanogaster, GI45553335, Length=116, Percent_Identity=51.7241379310345, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21356369, Length=116, Percent_Identity=51.7241379310345, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24645799, Length=116, Percent_Identity=51.7241379310345, Blast_Score=128, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 14839; Mature: 14707

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYPIQKTDAEWQALLQDKGAEPAAWQVTRHAATERPFTGKYEAHWADGSYHCVCCGAKL
CCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEECCHH
FDSDTKFDAGCGWPSFSLAVPGAIREIVDRSHGMVRTETVCAQCGAHLGHVFEDGPAPTG
CCCCCCCCCCCCCCCCCEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHH
LRYCMNSASLDFEPGGA
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TYPIQKTDAEWQALLQDKGAEPAAWQVTRHAATERPFTGKYEAHWADGSYHCVCCGAKL
CCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEECCHH
FDSDTKFDAGCGWPSFSLAVPGAIREIVDRSHGMVRTETVCAQCGAHLGHVFEDGPAPTG
CCCCCCCCCCCCCCCCCEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHH
LRYCMNSASLDFEPGGA
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA