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The map label for this gene is mog [H]

Identifier: 120610755

GI number: 120610755

Start: 2278783

End: 2279430

Strand: Reverse

Name: mog [H]

Synonym: Aave_2077

Alternate gene names: 120610755

Gene position: 2279430-2278783 (Counterclockwise)

Preceding gene: 120610756

Following gene: 120610751

Centisome position: 42.58

GC content: 69.14

Gene sequence:

>648_bases
ATGCCGCGCCCTGGAAGCAATGCAATGAACGAAGCACCTGGATTTTCCCTTCCCGCGCCCGAGCCGGTGCGCATCGGCAT
CGTGTCGGTGAGCGACCGCGCGAGCCGCGGCGTCTATGAGGACAAGGGCCTGCCCGCGCTGCGGCAGTGGCTGGAGCGGG
CGCTGCACAACCCGGTGCATTTCGAGGAGCGGCTCATCCCCGACGAGCAGGAGCGCATCAGTGCCACGCTCATCGATCTG
GTGGACGGCGCGGGCTGCCACCTGGTGCTGACCACCGGCGGCACGGGCCCCGCACCGCGCGACGTGACCCCCGAGGCCAC
GCTGGCCATCGCGCACCGCGAAATGCCAGGCTTCGGCGAGCAGATGCGGCAGATCAGCCTGCGCTTCGTGCCCACGGCCA
TCCTCTCGCGACAGGTGGCGGTGATCCGCCACGGCAGCCTGGTCATCAACCTGCCGGGGCAACCCAAGGCCATCGCGGAG
ACGCTCGAAGGGCTGAAGGACGAACAGGGAACAACGATCGTCCCGGGCATCTTCGCGGCCGTGCCCTACTGCATCGACCT
GATCGGCGGCCCCTACCTGGAGACGCGCGAGGCGGTGTGCAATGCGTTCAGGCCCAAGGACGCACGCAGGCCCGCACGGC
CGCAGTGA

Upstream 100 bases:

>100_bases
CGGGAGGACGACGCCAGTGGCCGGGCAAAGCCCGCTCCACGGCGCCTGCTGGCCTGGCCTGCTCCGCGGCCCTCTGACGG
ATGAGGCCGCGGTGAGCGAT

Downstream 100 bases:

>100_bases
ACCCTGGAACCAGCGCGGAACAAGCGCGAAGCCACCGGGGGAGGCGGGCCGGTGGACGCGCCCCGCCTACTTGCCCACCA
GCGCGTTGAGTTTCTCTGCC

Product: molybdopterin adenylyltransferase

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MPRPGSNAMNEAPGFSLPAPEPVRIGIVSVSDRASRGVYEDKGLPALRQWLERALHNPVHFEERLIPDEQERISATLIDL
VDGAGCHLVLTTGGTGPAPRDVTPEATLAIAHREMPGFGEQMRQISLRFVPTAILSRQVAVIRHGSLVINLPGQPKAIAE
TLEGLKDEQGTTIVPGIFAAVPYCIDLIGGPYLETREAVCNAFRPKDARRPARPQ

Sequences:

>Translated_215_residues
MPRPGSNAMNEAPGFSLPAPEPVRIGIVSVSDRASRGVYEDKGLPALRQWLERALHNPVHFEERLIPDEQERISATLIDL
VDGAGCHLVLTTGGTGPAPRDVTPEATLAIAHREMPGFGEQMRQISLRFVPTAILSRQVAVIRHGSLVINLPGQPKAIAE
TLEGLKDEQGTTIVPGIFAAVPYCIDLIGGPYLETREAVCNAFRPKDARRPARPQ
>Mature_214_residues
PRPGSNAMNEAPGFSLPAPEPVRIGIVSVSDRASRGVYEDKGLPALRQWLERALHNPVHFEERLIPDEQERISATLIDLV
DGAGCHLVLTTGGTGPAPRDVTPEATLAIAHREMPGFGEQMRQISLRFVPTAILSRQVAVIRHGSLVINLPGQPKAIAET
LEGLKDEQGTTIVPGIFAAVPYCIDLIGGPYLETREAVCNAFRPKDARRPARPQ

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=176, Percent_Identity=38.0681818181818, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI10880983, Length=176, Percent_Identity=38.0681818181818, Blast_Score=109, Evalue=2e-24,
Organism=Escherichia coli, GI1786190, Length=188, Percent_Identity=70.2127659574468, Blast_Score=272, Evalue=1e-74,
Organism=Escherichia coli, GI1787000, Length=145, Percent_Identity=33.7931034482759, Blast_Score=71, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17564954, Length=147, Percent_Identity=36.734693877551, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17136978, Length=169, Percent_Identity=32.5443786982249, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24638841, Length=169, Percent_Identity=32.5443786982249, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 23289; Mature: 23158

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPGSNAMNEAPGFSLPAPEPVRIGIVSVSDRASRGVYEDKGLPALRQWLERALHNPVH
CCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHCCCCCCCCCHHHHHHHHHHHCCCCC
FEERLIPDEQERISATLIDLVDGAGCHLVLTTGGTGPAPRDVTPEATLAIAHREMPGFGE
HHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHEEEHHCCCCCHHH
QMRQISLRFVPTAILSRQVAVIRHGSLVINLPGQPKAIAETLEGLKDEQGTTIVPGIFAA
HHHHHHHHHHHHHHHHHHHHEEECCEEEEECCCCCHHHHHHHHHHCCCCCCEECHHHHHH
VPYCIDLIGGPYLETREAVCNAFRPKDARRPARPQ
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PRPGSNAMNEAPGFSLPAPEPVRIGIVSVSDRASRGVYEDKGLPALRQWLERALHNPVH
CCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHCCCCCCCCCHHHHHHHHHHHCCCCC
FEERLIPDEQERISATLIDLVDGAGCHLVLTTGGTGPAPRDVTPEATLAIAHREMPGFGE
HHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHEEEHHCCCCCHHH
QMRQISLRFVPTAILSRQVAVIRHGSLVINLPGQPKAIAETLEGLKDEQGTTIVPGIFAA
HHHHHHHHHHHHHHHHHHHHEEECCEEEEECCCCCHHHHHHHHHHCCCCCCEECHHHHHH
VPYCIDLIGGPYLETREAVCNAFRPKDARRPARPQ
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]