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The map label for this gene is perM [H]

Identifier: 120610682

GI number: 120610682

Start: 2178214

End: 2179518

Strand: Reverse

Name: perM [H]

Synonym: Aave_2002

Alternate gene names: 120610682

Gene position: 2179518-2178214 (Counterclockwise)

Preceding gene: 120610685

Following gene: 120610679

Centisome position: 40.72

GC content: 71.26

Gene sequence:

>1305_bases
ATGCAGCTTTCCGCCCCCGCCCCGGACTCCCCGCCCGACGCCACCGCCATGCGTGCCTCCGCGCCGCCGCCCGCGGGCGA
CCCGCCCGCCGAACCACCGCCCGCCGGGGATCCACCGCCGGCCTCGCCGCCGGCAGGCGACCCGCCCGCGCCGGCCCCCG
GCCCGGCGGAGCCTCCGCCGCCACCGGCAGGCGCCTCGCCACCGCCCCCCTTCGTGCTGCACATGCCCGTGGATGTGCGC
AACCTGTCGCTCGCCCTGCTGGCGCTCTTCGCCGCCGTGGCCCTCCTGCACTGGGCCAGCGCCGTCTTCATTCCATTGAT
GTTGAGCCTGCTGCTCACCATCGCGCTGCAGCCCATCGTGACGGCGCTGCGGCGCTGGTACATCCCGCGCTGGCTCAGTG
CCGGCGTTCTGCTGCTGGGCATCGTCGGCGGCCTCGGCGGCACGGCCTGGTCGCTCTCCGACGGCGCGGCCGAACTGGTG
GACTCGCTGCCCGTGGCCGCGCGCAAGGTACGGGATGCCATGCGGACGAACATGCGCGGGCCGAGCCCGCTCGACACCAT
GCAGAAGGCCGCCAGCCAGATCGAGCAGGCCGCCACCGAAAGCATCCCGCCCCAGACGCGGCGCGGCGTGCAGCGCGTGG
TGATCGAGCGCGCGCCCTTCAACATCCGCGATTACGTATGGACCGGCACCGTGGGCCTGGTATCGGCCGCGGGCCAGCTC
ACCGTGGTGGTCTTCCTCACCTTCTTCTCGCTGGCCTCGGGCAACCTCTTCCGCCGCAAGCTGGTGCGCATCGCGGGCCA
GAGCCTCGAGCGCCGCAAGATCACCATGGAAGTGCTCGACGACATCACCGGACAGATCCAGCGCTACCTGCTCGTGCAGG
TGGCCACCAGCGTCCTGGTGGGCATCGGCACCGGCGTGGCCTATGCCCTGCTCGGGCTGGAGAACGCGGCCGTCTGGGGC
GTGGTGGCCGGCGTGCTCAACCTCGCTCCCTACGTCGGCTCCATCGTCGTGACGGGCGCCTCCGCCCTCGTCGCCTTCCT
GCAGTTCGGCACCGTGGACATGGCCCTGGCCATCGGCGGCGCATCCCTGCTCATCCACACCATCGTAGGCAACCTGCTCA
CCCCCTGGCTCACCAGCCGCACCAGCCGCATGAGCCCCGTCGCGGTGTTCGTCAGCGTGCTGGCCTGGGGATGGCTGTGG
GGGTTGTGGGGAGTGTTGCTGGGGATTCCGGTGATGATGGTGGTGAAGGCTGTCTGCGATCGGGTGGAGGATCTGAGGCC
TATCGGGGAGTTGTTGGGGGATTGA

Upstream 100 bases:

>100_bases
GTCTGGCGCCTGCGTCCATCGCGCCGACCGCGCCCCGCCGATGCCATGGCCGGGTGCCCGCCTACGCCCGCACGGGCTCC
GGCCGCGCCACAATCCGCGC

Downstream 100 bases:

>100_bases
GGGTTTTTGTTTTGAGGGCGGGGGCCGGGTCTCGGCCCGGCGGCCGAGTCACTTTCTTTCGCTTCGCCGAAAGAAAGTAA
CCAAAGAACGGGGTCGCATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MQLSAPAPDSPPDATAMRASAPPPAGDPPAEPPPAGDPPPASPPAGDPPAPAPGPAEPPPPPAGASPPPPFVLHMPVDVR
NLSLALLALFAAVALLHWASAVFIPLMLSLLLTIALQPIVTALRRWYIPRWLSAGVLLLGIVGGLGGTAWSLSDGAAELV
DSLPVAARKVRDAMRTNMRGPSPLDTMQKAASQIEQAATESIPPQTRRGVQRVVIERAPFNIRDYVWTGTVGLVSAAGQL
TVVVFLTFFSLASGNLFRRKLVRIAGQSLERRKITMEVLDDITGQIQRYLLVQVATSVLVGIGTGVAYALLGLENAAVWG
VVAGVLNLAPYVGSIVVTGASALVAFLQFGTVDMALAIGGASLLIHTIVGNLLTPWLTSRTSRMSPVAVFVSVLAWGWLW
GLWGVLLGIPVMMVVKAVCDRVEDLRPIGELLGD

Sequences:

>Translated_434_residues
MQLSAPAPDSPPDATAMRASAPPPAGDPPAEPPPAGDPPPASPPAGDPPAPAPGPAEPPPPPAGASPPPPFVLHMPVDVR
NLSLALLALFAAVALLHWASAVFIPLMLSLLLTIALQPIVTALRRWYIPRWLSAGVLLLGIVGGLGGTAWSLSDGAAELV
DSLPVAARKVRDAMRTNMRGPSPLDTMQKAASQIEQAATESIPPQTRRGVQRVVIERAPFNIRDYVWTGTVGLVSAAGQL
TVVVFLTFFSLASGNLFRRKLVRIAGQSLERRKITMEVLDDITGQIQRYLLVQVATSVLVGIGTGVAYALLGLENAAVWG
VVAGVLNLAPYVGSIVVTGASALVAFLQFGTVDMALAIGGASLLIHTIVGNLLTPWLTSRTSRMSPVAVFVSVLAWGWLW
GLWGVLLGIPVMMVVKAVCDRVEDLRPIGELLGD
>Mature_434_residues
MQLSAPAPDSPPDATAMRASAPPPAGDPPAEPPPAGDPPPASPPAGDPPAPAPGPAEPPPPPAGASPPPPFVLHMPVDVR
NLSLALLALFAAVALLHWASAVFIPLMLSLLLTIALQPIVTALRRWYIPRWLSAGVLLLGIVGGLGGTAWSLSDGAAELV
DSLPVAARKVRDAMRTNMRGPSPLDTMQKAASQIEQAATESIPPQTRRGVQRVVIERAPFNIRDYVWTGTVGLVSAAGQL
TVVVFLTFFSLASGNLFRRKLVRIAGQSLERRKITMEVLDDITGQIQRYLLVQVATSVLVGIGTGVAYALLGLENAAVWG
VVAGVLNLAPYVGSIVVTGASALVAFLQFGTVDMALAIGGASLLIHTIVGNLLTPWLTSRTSRMSPVAVFVSVLAWGWLW
GLWGVLLGIPVMMVVKAVCDRVEDLRPIGELLGD

Specific function: Unknown

COG id: COG0628

COG function: function code R; Predicted permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0118 (perM) family [H]

Homologues:

Organism=Escherichia coli, GI1788838, Length=363, Percent_Identity=28.3746556473829, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87082271, Length=353, Percent_Identity=23.7960339943343, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787885, Length=149, Percent_Identity=32.8859060402685, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002549 [H]

Pfam domain/function: PF01594 UPF0118 [H]

EC number: NA

Molecular weight: Translated: 45456; Mature: 45456

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSAPAPDSPPDATAMRASAPPPAGDPPAEPPPAGDPPPASPPAGDPPAPAPGPAEPPP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPAGASPPPPFVLHMPVDVRNLSLALLALFAAVALLHWASAVFIPLMLSLLLTIALQPIV
CCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALRRWYIPRWLSAGVLLLGIVGGLGGTAWSLSDGAAELVDSLPVAARKVRDAMRTNMRG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHCCCC
PSPLDTMQKAASQIEQAATESIPPQTRRGVQRVVIERAPFNIRDYVWTGTVGLVSAAGQL
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHCCCHH
TVVVFLTFFSLASGNLFRRKLVRIAGQSLERRKITMEVLDDITGQIQRYLLVQVATSVLV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIGTGVAYALLGLENAAVWGVVAGVLNLAPYVGSIVVTGASALVAFLQFGTVDMALAIGG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLLIHTIVGNLLTPWLTSRTSRMSPVAVFVSVLAWGWLWGLWGVLLGIPVMMVVKAVCD
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVEDLRPIGELLGD
HHHHHHHHHHHHCC
>Mature Secondary Structure
MQLSAPAPDSPPDATAMRASAPPPAGDPPAEPPPAGDPPPASPPAGDPPAPAPGPAEPPP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPAGASPPPPFVLHMPVDVRNLSLALLALFAAVALLHWASAVFIPLMLSLLLTIALQPIV
CCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALRRWYIPRWLSAGVLLLGIVGGLGGTAWSLSDGAAELVDSLPVAARKVRDAMRTNMRG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHCCCC
PSPLDTMQKAASQIEQAATESIPPQTRRGVQRVVIERAPFNIRDYVWTGTVGLVSAAGQL
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHCCCHH
TVVVFLTFFSLASGNLFRRKLVRIAGQSLERRKITMEVLDDITGQIQRYLLVQVATSVLV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIGTGVAYALLGLENAAVWGVVAGVLNLAPYVGSIVVTGASALVAFLQFGTVDMALAIGG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLLIHTIVGNLLTPWLTSRTSRMSPVAVFVSVLAWGWLWGLWGVLLGIPVMMVVKAVCD
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVEDLRPIGELLGD
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]