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The map label for this gene is 120610624

Identifier: 120610624

GI number: 120610624

Start: 2105384

End: 2106334

Strand: Direct

Name: 120610624

Synonym: Aave_1944

Alternate gene names: NA

Gene position: 2105384-2106334 (Clockwise)

Preceding gene: 120610623

Following gene: 120610626

Centisome position: 39.33

GC content: 70.14

Gene sequence:

>951_bases
TTGCGCTTTCCTGGCGGGCCGGATGCCGGCCGCGGCAAGCCCTGTGTTTTCGAGAATCGAGCGCGTACAGCTATGACTTT
GATCGCAATCATCCTGGCCACCCTGGCCGCGGGTATCGGCAGCGTGTGGGTGGCGGCCCTGCTCATGCGGGCCGGCTGGG
GGGACGGCCGCTCGGGCATCGGCCCGCGGCACCTCCTGAGCTTCGCCGCCGGCGCGCTGCTGGCCACGGCCTTCATGCAT
TTGCTACCCGAGGCCTTCGAGAGCCAGGCCGGCGCGCACGAACTCTTCGCCACGCTGCTGGTGGGGCTGGTCTTCTTCTT
CCTGCTGGACAAGGCGGAGCTCTGGCACCACGGCCACGAGCACGGCGTGGGGCCGGCCAACGACGACCCGGGTACGGGGG
GAGGGCACGCGCACGCCCATGGACACACCCACGATGGCCACGGGCACGATGCACACGGCCATGGGCACCACTCCCACGCC
CATTCCCACTCGCATCGCGGCTCCGGCGGCTGGGCCCTGCTCACGGGCGACAGCGTCCACTGCTTCGGCGACGGTGTCCT
GATTGCCTCCGCCTTCCTGGCCGACCTGCGCCTGGGCGCCATCGCCGCGCTGGCCGTCCTGGCCCACGAAGTGCCGCACC
ACATGGGCGATCTGGTGGTGCTGCGCCAGTCCAGCGGCGACCGGCGCGCGGCCCTGGTCAAGGTGTCCCTGGCCGGAGCG
GTCACCGCGCTCGGGGGCGTGGTGGGCTATTTCCTGGTGGGCGAGCTGCAGGACTGGCTGCCGTATTTCCTGGCCATCGC
GTCCAGCAGCTTCGTCTATGTGGCGCTGGCCGACCTCATCCCCCAATTGCAAAAGCGCCTGACGGCCGCGCAGACGCTGG
CGCAGATCGCGTGGCTGCTGGGGGGCATGGCGGTGGTCACGCTGGTGAGCGGGATGGCGCACGCACATTAA

Upstream 100 bases:

>100_bases
GAAGCGCGCGCTGGCGTGGTTCAAGGCGCACGGCGTGGGCTGACGCGCCGCCCCGCCGGGCGCCGCGTTCCGCAGCAAAG
CCCTTCGGGGCTTTTTTCGT

Downstream 100 bases:

>100_bases
GGGGCACCCCCCTGAGCGGCTTCGCCGCCTCCCCCCTCTCTCGCCATGCTGCGCATGGCGGGCGGGGGGACGCAGCCCTC
GCTGCGGGGGGCCCTTGCTT

Product: zinc/iron permease

Products: NA

Alternate protein names: ZIP Zinc Transporter; Zinc Transporter ZIP; Metal Cation Transporter ZIP Family; Transmembrane Protein; Zinc Transporter; Zinc Transporter Foi; ZIP Zinc Transporter Family; Divalent Heavy-Metal Cations Transporter

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MRFPGGPDAGRGKPCVFENRARTAMTLIAIILATLAAGIGSVWVAALLMRAGWGDGRSGIGPRHLLSFAAGALLATAFMH
LLPEAFESQAGAHELFATLLVGLVFFFLLDKAELWHHGHEHGVGPANDDPGTGGGHAHAHGHTHDGHGHDAHGHGHHSHA
HSHSHRGSGGWALLTGDSVHCFGDGVLIASAFLADLRLGAIAALAVLAHEVPHHMGDLVVLRQSSGDRRAALVKVSLAGA
VTALGGVVGYFLVGELQDWLPYFLAIASSSFVYVALADLIPQLQKRLTAAQTLAQIAWLLGGMAVVTLVSGMAHAH

Sequences:

>Translated_316_residues
MRFPGGPDAGRGKPCVFENRARTAMTLIAIILATLAAGIGSVWVAALLMRAGWGDGRSGIGPRHLLSFAAGALLATAFMH
LLPEAFESQAGAHELFATLLVGLVFFFLLDKAELWHHGHEHGVGPANDDPGTGGGHAHAHGHTHDGHGHDAHGHGHHSHA
HSHSHRGSGGWALLTGDSVHCFGDGVLIASAFLADLRLGAIAALAVLAHEVPHHMGDLVVLRQSSGDRRAALVKVSLAGA
VTALGGVVGYFLVGELQDWLPYFLAIASSSFVYVALADLIPQLQKRLTAAQTLAQIAWLLGGMAVVTLVSGMAHAH
>Mature_316_residues
MRFPGGPDAGRGKPCVFENRARTAMTLIAIILATLAAGIGSVWVAALLMRAGWGDGRSGIGPRHLLSFAAGALLATAFMH
LLPEAFESQAGAHELFATLLVGLVFFFLLDKAELWHHGHEHGVGPANDDPGTGGGHAHAHGHTHDGHGHDAHGHGHHSHA
HSHSHRGSGGWALLTGDSVHCFGDGVLIASAFLADLRLGAIAALAVLAHEVPHHMGDLVVLRQSSGDRRAALVKVSLAGA
VTALGGVVGYFLVGELQDWLPYFLAIASSSFVYVALADLIPQLQKRLTAAQTLAQIAWLLGGMAVVTLVSGMAHAH

Specific function: Unknown

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40255101, Length=272, Percent_Identity=29.0441176470588, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI190014617, Length=279, Percent_Identity=28.3154121863799, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI187936949, Length=178, Percent_Identity=28.6516853932584, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI55741750, Length=178, Percent_Identity=28.6516853932584, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI153252201, Length=113, Percent_Identity=31.858407079646, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI223633937, Length=130, Percent_Identity=30, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI223633939, Length=269, Percent_Identity=24.1635687732342, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI205830407, Length=157, Percent_Identity=29.2993630573248, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI24586665, Length=157, Percent_Identity=29.2993630573248, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI205830403, Length=157, Percent_Identity=29.2993630573248, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71998183, Length=153, Percent_Identity=32.6797385620915, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71992548, Length=324, Percent_Identity=25.3086419753086, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538884, Length=219, Percent_Identity=22.3744292237443, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71994730, Length=304, Percent_Identity=25.9868421052632, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24651189, Length=290, Percent_Identity=25.8620689655172, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24651193, Length=290, Percent_Identity=25.8620689655172, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24651187, Length=290, Percent_Identity=25.8620689655172, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24651191, Length=290, Percent_Identity=25.8620689655172, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24651195, Length=290, Percent_Identity=25.8620689655172, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24651197, Length=290, Percent_Identity=25.8620689655172, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45549201, Length=141, Percent_Identity=31.2056737588652, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17864610, Length=167, Percent_Identity=26.3473053892216, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI161083817, Length=114, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24664383, Length=114, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 32912; Mature: 32912

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFPGGPDAGRGKPCVFENRARTAMTLIAIILATLAAGIGSVWVAALLMRAGWGDGRSGI
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GPRHLLSFAAGALLATAFMHLLPEAFESQAGAHELFATLLVGLVFFFLLDKAELWHHGHE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HGVGPANDDPGTGGGHAHAHGHTHDGHGHDAHGHGHHSHAHSHSHRGSGGWALLTGDSVH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEE
CFGDGVLIASAFLADLRLGAIAALAVLAHEVPHHMGDLVVLRQSSGDRRAALVKVSLAGA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHEEEHHHHHH
VTALGGVVGYFLVGELQDWLPYFLAIASSSFVYVALADLIPQLQKRLTAAQTLAQIAWLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGMAVVTLVSGMAHAH
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFPGGPDAGRGKPCVFENRARTAMTLIAIILATLAAGIGSVWVAALLMRAGWGDGRSGI
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GPRHLLSFAAGALLATAFMHLLPEAFESQAGAHELFATLLVGLVFFFLLDKAELWHHGHE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HGVGPANDDPGTGGGHAHAHGHTHDGHGHDAHGHGHHSHAHSHSHRGSGGWALLTGDSVH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEE
CFGDGVLIASAFLADLRLGAIAALAVLAHEVPHHMGDLVVLRQSSGDRRAALVKVSLAGA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHEEEHHHHHH
VTALGGVVGYFLVGELQDWLPYFLAIASSSFVYVALADLIPQLQKRLTAAQTLAQIAWLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGMAVVTLVSGMAHAH
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA