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The map label for this gene is tcp [H]

Identifier: 120610554

GI number: 120610554

Start: 2031743

End: 2033536

Strand: Direct

Name: tcp [H]

Synonym: Aave_1874

Alternate gene names: 120610554

Gene position: 2031743-2033536 (Clockwise)

Preceding gene: 120610553

Following gene: 120610555

Centisome position: 37.96

GC content: 64.44

Gene sequence:

>1794_bases
ATGTTGTCATCCATTCGCACCCGCGTCGTAGGTGTCTCGGTATTGCTGGTCGCGCTCTCGGTCATCGTCAGCACCGCGAC
CAATTACCTGATCGCAAAATCGAGCATGTCGGCGGCGGCCGATCAGGATTTGATCACTTCGGTCAACGAGCATGCGGTGG
TCATCGGCGACTGGGTCGCTGACAAGTCCCGCATGGTGGCTTCGCTGCAGGATGTGGTGCTGACGAGTAGCCCGGATATC
GCACTCAAGCAGATTGCCGTCGCCGGTGGTTTCTACGACGTCGGCGTCGGCTATCCGGACAAATCCGCGAAATTCACGGA
TTGGCCGAACATTCCGCCCACGTACGATCCGACCAGCCGCCCCTGGTACCAGGGCGCGGTCCAGGCCGGTAAACCCGTCG
CCATTCCGTACGTCAGCACCAGCAAGCTCCTGCTGGTGGCACTGGCCCTGCCGGTGATGCGCGAAGGGGCGCTCAAGGCC
GTCCTGGTCGGGGATATTGCGCTGGACAGCGTGGTGGAGAACATCAAGTCGATCCAGCCGACACCAGGAAGCTTCGGCAT
GTTGATCGACCGGAGCGGCCGCATCATCGCGCACGCTGATACAAAACTGCGATTCAGGCAGGTCACCGATATCGCGCCCG
ATTTTTCCCAGCTCTCCGTCGCTTCCACGGGCCCGGGCTCGGCGCAGATGAAGGTCGTCGTCGATGGCCGGGCAAAGCTG
GTGCGTGCGCAGGATGTCCGCGGCACCGACTGGCGCATCGTGATCGTCATGGATGAAGCCGAGGTGATGGCGGGCTCGCG
TTCCTTGCTGGTGGCCTCGCTGGTGTCGCTGCTCATCATCGTCGGCATCGCCTCCGTGATCGGCATCGCCATGACGGCGA
CCAGCTTCCGCCGGCTCGAGCAAGTCAGCCAGGCCATGACGGCCATCGGCTCGGGGTCCGGCGACCTGACGCAGCGCCTG
CCGGACCAGGGCAAGGACGAGGTCGCCACCATCGCCCGGTCGTTCAACCAGTTCGTCGGCAAAATACAGAGCGTGATGCT
GGAAGTCCGGGATGCCGGAGCGTCGGTCCTGACTGCCGCCGATGAAATCGCGAGCGCCAGCCAGGACTTGTCCGCCCGTA
CCGAGCTGGCTGCCGCCAATCTCGAGGAAACCGCTGCCTCGATGGCCCACATCTCGGGAACGGTCGACAGCTCCGCCGCG
GCGGCCCTGGAGGCCGACCAGCGTTCCAGTGCCGCGACGGAAATGGCCTCGCAGGGGGGCAGAATCGTCTCCGAGGCGGT
CGGTACGATGGAAGAGATCGAAAAGGTCTCGGGACAGATCGGTGCCATCATCACGGTCATCGACGGCATCGCATTCCAGA
CCAACATTCTCGCGCTCAATGCAGCGGTGGAAGCCGCCCGTGCCGGGGAGCAGGGGCGCGGTTTTGCCGTCGTCGCCCAT
GAAGTGCGCAACCTGGCGCAGCGCAGTGCAGAGTCCGCACGCGAGGTCAAGCAGCTGGTGGAGTCCACGGTGTCGCGCGT
TTCCGCCGGGTCGGTCCAGGTGCGCCGGGCCGGCAAGACCATGAGCGAGATCATCTCCCATTCCGCCGAAGTGCAATCCG
TCATTTCCGGGATCGCGCGTGCCGCCGCAGAGCAGACGCGCGGCATCCAGGAAGTCAATCAGGCGGTCGTCCAGCTGGAT
GCGATGGTGCAGCAGAACGCTTCGCTGGTGGAGCAATCCGCTGCCGCCTCGGGCACCTTGCAGACGCAGGCCAATGCACT
GGCCGCGACCATCGGCCGGTTCAAGATCGCCTGA

Upstream 100 bases:

>100_bases
GATGCACAGCACGCATGCGCATAACGTTTTCCCTGTGGTATGTTTGTTTTTGTAAGAATGCAGTCAATTGGTTTGATTGC
AAAAACAAAACTCCACCAAA

Downstream 100 bases:

>100_bases
CCTTCTCCACTGCCGGGAAGGGCGGGAGACGGCTGCCGCCTCCGCTCCACCAGCGCCCCGCCGGCACCGCGTCCATGCGT
GAATGGATCAGCGCGCCTAA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MLSSIRTRVVGVSVLLVALSVIVSTATNYLIAKSSMSAAADQDLITSVNEHAVVIGDWVADKSRMVASLQDVVLTSSPDI
ALKQIAVAGGFYDVGVGYPDKSAKFTDWPNIPPTYDPTSRPWYQGAVQAGKPVAIPYVSTSKLLLVALALPVMREGALKA
VLVGDIALDSVVENIKSIQPTPGSFGMLIDRSGRIIAHADTKLRFRQVTDIAPDFSQLSVASTGPGSAQMKVVVDGRAKL
VRAQDVRGTDWRIVIVMDEAEVMAGSRSLLVASLVSLLIIVGIASVIGIAMTATSFRRLEQVSQAMTAIGSGSGDLTQRL
PDQGKDEVATIARSFNQFVGKIQSVMLEVRDAGASVLTAADEIASASQDLSARTELAAANLEETAASMAHISGTVDSSAA
AALEADQRSSAATEMASQGGRIVSEAVGTMEEIEKVSGQIGAIITVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAH
EVRNLAQRSAESAREVKQLVESTVSRVSAGSVQVRRAGKTMSEIISHSAEVQSVISGIARAAAEQTRGIQEVNQAVVQLD
AMVQQNASLVEQSAAASGTLQTQANALAATIGRFKIA

Sequences:

>Translated_597_residues
MLSSIRTRVVGVSVLLVALSVIVSTATNYLIAKSSMSAAADQDLITSVNEHAVVIGDWVADKSRMVASLQDVVLTSSPDI
ALKQIAVAGGFYDVGVGYPDKSAKFTDWPNIPPTYDPTSRPWYQGAVQAGKPVAIPYVSTSKLLLVALALPVMREGALKA
VLVGDIALDSVVENIKSIQPTPGSFGMLIDRSGRIIAHADTKLRFRQVTDIAPDFSQLSVASTGPGSAQMKVVVDGRAKL
VRAQDVRGTDWRIVIVMDEAEVMAGSRSLLVASLVSLLIIVGIASVIGIAMTATSFRRLEQVSQAMTAIGSGSGDLTQRL
PDQGKDEVATIARSFNQFVGKIQSVMLEVRDAGASVLTAADEIASASQDLSARTELAAANLEETAASMAHISGTVDSSAA
AALEADQRSSAATEMASQGGRIVSEAVGTMEEIEKVSGQIGAIITVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAH
EVRNLAQRSAESAREVKQLVESTVSRVSAGSVQVRRAGKTMSEIISHSAEVQSVISGIARAAAEQTRGIQEVNQAVVQLD
AMVQQNASLVEQSAAASGTLQTQANALAATIGRFKIA
>Mature_597_residues
MLSSIRTRVVGVSVLLVALSVIVSTATNYLIAKSSMSAAADQDLITSVNEHAVVIGDWVADKSRMVASLQDVVLTSSPDI
ALKQIAVAGGFYDVGVGYPDKSAKFTDWPNIPPTYDPTSRPWYQGAVQAGKPVAIPYVSTSKLLLVALALPVMREGALKA
VLVGDIALDSVVENIKSIQPTPGSFGMLIDRSGRIIAHADTKLRFRQVTDIAPDFSQLSVASTGPGSAQMKVVVDGRAKL
VRAQDVRGTDWRIVIVMDEAEVMAGSRSLLVASLVSLLIIVGIASVIGIAMTATSFRRLEQVSQAMTAIGSGSGDLTQRL
PDQGKDEVATIARSFNQFVGKIQSVMLEVRDAGASVLTAADEIASASQDLSARTELAAANLEETAASMAHISGTVDSSAA
AALEADQRSSAATEMASQGGRIVSEAVGTMEEIEKVSGQIGAIITVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAH
EVRNLAQRSAESAREVKQLVESTVSRVSAGSVQVRRAGKTMSEIISHSAEVQSVISGIARAAAEQTRGIQEVNQAVVQLD
AMVQQNASLVEQSAAASGTLQTQANALAATIGRFKIA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=253, Percent_Identity=50.197628458498, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1788195, Length=284, Percent_Identity=48.5915492957746, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1788194, Length=359, Percent_Identity=42.3398328690808, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1787690, Length=414, Percent_Identity=37.9227053140097, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1789453, Length=400, Percent_Identity=31.5, Blast_Score=182, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 62275; Mature: 62275

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSIRTRVVGVSVLLVALSVIVSTATNYLIAKSSMSAAADQDLITSVNEHAVVIGDWVA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHCCCCCEEEEEECCC
DKSRMVASLQDVVLTSSPDIALKQIAVAGGFYDVGVGYPDKSAKFTDWPNIPPTYDPTSR
CHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCC
PWYQGAVQAGKPVAIPYVSTSKLLLVALALPVMREGALKAVLVGDIALDSVVENIKSIQP
CHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCC
TPGSFGMLIDRSGRIIAHADTKLRFRQVTDIAPDFSQLSVASTGPGSAQMKVVVDGRAKL
CCCCCCEEEECCCCEEEECCCHHHHHHHHHCCCCHHHEEECCCCCCCCEEEEEECCCHHE
VRAQDVRGTDWRIVIVMDEAEVMAGSRSLLVASLVSLLIIVGIASVIGIAMTATSFRRLE
EEECCCCCCCEEEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVSQAMTAIGSGSGDLTQRLPDQGKDEVATIARSFNQFVGKIQSVMLEVRDAGASVLTAA
HHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
DEIASASQDLSARTELAAANLEETAASMAHISGTVDSSAAAALEADQRSSAATEMASQGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
RIVSEAVGTMEEIEKVSGQIGAIITVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAH
HHHHHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHEEHHHHHHHHHCCCCCCCHHHHHH
EVRNLAQRSAESAREVKQLVESTVSRVSAGSVQVRRAGKTMSEIISHSAEVQSVISGIAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAEQTRGIQEVNQAVVQLDAMVQQNASLVEQSAAASGTLQTQANALAATIGRFKIA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSSIRTRVVGVSVLLVALSVIVSTATNYLIAKSSMSAAADQDLITSVNEHAVVIGDWVA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHCCCCCEEEEEECCC
DKSRMVASLQDVVLTSSPDIALKQIAVAGGFYDVGVGYPDKSAKFTDWPNIPPTYDPTSR
CHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCC
PWYQGAVQAGKPVAIPYVSTSKLLLVALALPVMREGALKAVLVGDIALDSVVENIKSIQP
CHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCC
TPGSFGMLIDRSGRIIAHADTKLRFRQVTDIAPDFSQLSVASTGPGSAQMKVVVDGRAKL
CCCCCCEEEECCCCEEEECCCHHHHHHHHHCCCCHHHEEECCCCCCCCEEEEEECCCHHE
VRAQDVRGTDWRIVIVMDEAEVMAGSRSLLVASLVSLLIIVGIASVIGIAMTATSFRRLE
EEECCCCCCCEEEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVSQAMTAIGSGSGDLTQRLPDQGKDEVATIARSFNQFVGKIQSVMLEVRDAGASVLTAA
HHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
DEIASASQDLSARTELAAANLEETAASMAHISGTVDSSAAAALEADQRSSAATEMASQGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
RIVSEAVGTMEEIEKVSGQIGAIITVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAH
HHHHHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHEEHHHHHHHHHCCCCCCCHHHHHH
EVRNLAQRSAESAREVKQLVESTVSRVSAGSVQVRRAGKTMSEIISHSAEVQSVISGIAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAEQTRGIQEVNQAVVQLDAMVQQNASLVEQSAAASGTLQTQANALAATIGRFKIA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]