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The map label for this gene is pepN [H]

Identifier: 120610524

GI number: 120610524

Start: 1998935

End: 2001646

Strand: Reverse

Name: pepN [H]

Synonym: Aave_1844

Alternate gene names: 120610524

Gene position: 2001646-1998935 (Counterclockwise)

Preceding gene: 120610525

Following gene: 120610523

Centisome position: 37.39

GC content: 69.73

Gene sequence:

>2712_bases
ATGCGTGAAGGACAACCCGCCACGGCCATCCACCGTGCCGACTACACCGCCCCCGCGTTCTGGATCGACAGCGTGGACCT
CACGTTCGACCTGGACCCCGCCAAGACCCGCGTGCTCAGCCGCCTGCGCGTGCGCCGCAACGCCGACGTGCCGCCGGCGC
CCCTGCGCCTGGACGGCGAGGAGCTGAACCTCGCGCGGGTGCTGGTCAACGGGGCGGGCACGTCCTTCAAGCTCGAAGGC
AGCCAGCTCGTGCTGGAGAACCTGCCCGAGGGCCACGAGCCCTTCGATCTGGAGATCTTCACCACCTGCTGCCCCGCCAA
GAACACCCAGCTCTCGGGCCTCTACGTGAGCCAGGGCACCTTCTTCACGCAGTGCGAGGCCGAGGGCTTCCGCCGCATCA
CCTACTTCCTCGACCGCCCCGACGTGATGGCGAGCTACACCGTCACGCTGCGCGCCGACAAGGCAGAGTACCCGGTGCTG
CTGTCCAACGGCAACCTGGTGGACCAGGGCCTGCTCGACGACGGCCGGCACTTCGCCAGGTGGGTCGATCCGCACAAGAA
GCCCTGCTACCTGTTCGCGCTGGTGGCCGGCAAGCTGGTGGCGCGCGAGCAGCGCATCCGCGCCCGGTCGGGCAATGACC
ACCTGCTGCAGATCTTCGTGCGCCCGGGCGACCTGGAGAAGACCGAGCACGCGATGAATTCGCTCATGGCCAGCATCGCC
TGGGACGAGGCGCGCTTCGGCCTGCCGCTCGACCTGGAGCGCTTCATGATCGTCGCCACCAGCGACTTCAACATGGGCGC
GATGGAGAACAAGGGCCTGAACATCTTCAACACGAAGTACGTGCTGGCGAGCCAGTCCACGGCCACGGATGCCGATTTCG
GGAACATCGAATCGGTGGTGGGCCATGAATACTTCCACAACTGGACCGGCAACCGCGTGACCTGCCGCGACTGGTTCCAG
CTATCGCTCAAGGAAGGCCTCACCGTCTTCCGCGACCAGGAATTCAGCCAGGATCTCTCGGGCAGCCCGTCGGCCCGCGC
CGTCAAGCGCATCGAGGACGTGCGCGTGCTGCGCACCGTGCAGTTCCCCGAGGACGCCGGCCCGATGGCGCATCCGGTGC
GCCCCGACAGCTACGTCGAGATCAACAACTTCTACACCGTCACCATCTACGAGAAGGGTGCCGAGGTCGTGCGCATGATG
CACACGCTCGTCGGCCGCGACGGTTTCGCCGCGGGCATGAAGCTCTACTTCGAGCGCCACGACGGCCAGGCCGTGACGTG
CGACGACTTCGCCCAGGCCATCGCCGACGCCAACCCGGACAGCGAGCTCGCGCGCCTGCTGCCGCAGTTCAAACGCTGGT
ACGCCCAGGCCGGCACGCCGCGCGTGCGCGCCCGCGGAGCCTACGACGCCGGCGCACGCACCTACACGCTCACGCTGGAG
CAAAGCATCGCGCCCACACCCGGCCAGCCCGTGAAGGAACCGATGGTGATACCCGTGGCGCTGGGACTGCTCGGCGCCGA
CGGCAGCGCCCTGCCCCTGCAGCTGGAAGGCGAGGCCGAAGCCGGCGGACCGGACCGCACCGTGGTGCTCACCGAGCCGG
TACACACCTACACGTTCGTGAACGTGCCGTCGGAGCCGGTGCCGTCGCTGCTGCGCGGCTTCAGCGCCCCGGTGCTGCTG
GACATCGAGGCCACAGACGCGCAATTGCTCGCGCTGCTCGCGCACGACACCGACCCGTTCAACCGCTGGGAGGCCGGCCA
GCGCCTCGCGCTGCGCATCGCCATCCAGGCCATCGGCGACACGTCGCTGGACGTCCCCGCCGACGGCGTGCTGCAGCGGG
AACTGCTGCCGGCGAGCTTCGTCGCCGCGATGCGCGACGTGCTGCGCCATCCAGCGCTGGACGCCGCCTTCAAGGAACTG
GTACTCGCCCTGCCCTCCGAGGGCTACATCGCCGAGCAGCTCGACGTGGTCGATCCGCAGCGCGTGCACGCGGTGCGCGA
GGCCATGCGCCAGCAACTGGCCGTGGCGCTGCAGGCGGACTGGGAATGGACATGGGAGCAGCACCACGACACCGGCGCCT
ACCGCCCTGACGCGATCTCCTCCGGCCGCCGCGCGCTGGCGGGCATGGCGCTGTCGATGCTGTGCCTGGCGGCGCGCCGC
ACGGGTGATGCCGTCTGGCCGGGCAAGGCCTACCAGCGCTTCAAGGACGCGGGCAACATGACCGACCGCTTCAACGCGCT
GACCGCCCTGGTGGCCAGCGGCCAGCCCCTCGCCGCGCAGGCCCTGGCGCGCTTCCATGCGATGTTCAAGGACGAGGCGC
TGGTGCTGGACAAGTGGTTCTCGCTGCAGGCCGGCGCGCCGGACCGCGGCGGCGACGTGCTGCCCGCCGTGAAGCAGCTG
ATGAAGCACCCGGACTTCAGCCTCAAGAACCCGAACCGCGCGCGCAGCCTGATCTTCAGCTACTGCAGCGCCAACCCCGG
AGCCTTCCATCGCCAGGACGCCGCGGGCTACGCCTTCTGGGCGGACCGCGTGATCGAACTCGACGCGCTGAACCCGCAGG
TGGCGGCCCGCCTCGCGCGGGCCCTCGACCGCTGGAGCAAGCTCGCCGAGCCCTACCGGACGGCCGCGCGCGACGCCATC
GCCCGCGTGGCGGCGAAGCCCGACCTGTCCAACGACGTGCGCGAGGTGGTCGGCCGCGCGCTCGCCGACTGA

Upstream 100 bases:

>100_bases
CCAGCGCCTCGACCGCGCAGTCCTGAACCTCGTCCAATGACCCCCATTTACCCCATCCCCGCCGTGAGACGGCTCGTGCC
CAACCTGGAGATTACGCCCC

Downstream 100 bases:

>100_bases
TCCGGCAGGCCGGACACCCCTTTCGAAAAAGAACCGAGAGATCCCACCGAACATGGCACAACGCATCAGCCTCACCCGCT
ACCTCGTCGAGCAGCAGCGC

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 903; Mature: 903

Protein sequence:

>903_residues
MREGQPATAIHRADYTAPAFWIDSVDLTFDLDPAKTRVLSRLRVRRNADVPPAPLRLDGEELNLARVLVNGAGTSFKLEG
SQLVLENLPEGHEPFDLEIFTTCCPAKNTQLSGLYVSQGTFFTQCEAEGFRRITYFLDRPDVMASYTVTLRADKAEYPVL
LSNGNLVDQGLLDDGRHFARWVDPHKKPCYLFALVAGKLVAREQRIRARSGNDHLLQIFVRPGDLEKTEHAMNSLMASIA
WDEARFGLPLDLERFMIVATSDFNMGAMENKGLNIFNTKYVLASQSTATDADFGNIESVVGHEYFHNWTGNRVTCRDWFQ
LSLKEGLTVFRDQEFSQDLSGSPSARAVKRIEDVRVLRTVQFPEDAGPMAHPVRPDSYVEINNFYTVTIYEKGAEVVRMM
HTLVGRDGFAAGMKLYFERHDGQAVTCDDFAQAIADANPDSELARLLPQFKRWYAQAGTPRVRARGAYDAGARTYTLTLE
QSIAPTPGQPVKEPMVIPVALGLLGADGSALPLQLEGEAEAGGPDRTVVLTEPVHTYTFVNVPSEPVPSLLRGFSAPVLL
DIEATDAQLLALLAHDTDPFNRWEAGQRLALRIAIQAIGDTSLDVPADGVLQRELLPASFVAAMRDVLRHPALDAAFKEL
VLALPSEGYIAEQLDVVDPQRVHAVREAMRQQLAVALQADWEWTWEQHHDTGAYRPDAISSGRRALAGMALSMLCLAARR
TGDAVWPGKAYQRFKDAGNMTDRFNALTALVASGQPLAAQALARFHAMFKDEALVLDKWFSLQAGAPDRGGDVLPAVKQL
MKHPDFSLKNPNRARSLIFSYCSANPGAFHRQDAAGYAFWADRVIELDALNPQVAARLARALDRWSKLAEPYRTAARDAI
ARVAAKPDLSNDVREVVGRALAD

Sequences:

>Translated_903_residues
MREGQPATAIHRADYTAPAFWIDSVDLTFDLDPAKTRVLSRLRVRRNADVPPAPLRLDGEELNLARVLVNGAGTSFKLEG
SQLVLENLPEGHEPFDLEIFTTCCPAKNTQLSGLYVSQGTFFTQCEAEGFRRITYFLDRPDVMASYTVTLRADKAEYPVL
LSNGNLVDQGLLDDGRHFARWVDPHKKPCYLFALVAGKLVAREQRIRARSGNDHLLQIFVRPGDLEKTEHAMNSLMASIA
WDEARFGLPLDLERFMIVATSDFNMGAMENKGLNIFNTKYVLASQSTATDADFGNIESVVGHEYFHNWTGNRVTCRDWFQ
LSLKEGLTVFRDQEFSQDLSGSPSARAVKRIEDVRVLRTVQFPEDAGPMAHPVRPDSYVEINNFYTVTIYEKGAEVVRMM
HTLVGRDGFAAGMKLYFERHDGQAVTCDDFAQAIADANPDSELARLLPQFKRWYAQAGTPRVRARGAYDAGARTYTLTLE
QSIAPTPGQPVKEPMVIPVALGLLGADGSALPLQLEGEAEAGGPDRTVVLTEPVHTYTFVNVPSEPVPSLLRGFSAPVLL
DIEATDAQLLALLAHDTDPFNRWEAGQRLALRIAIQAIGDTSLDVPADGVLQRELLPASFVAAMRDVLRHPALDAAFKEL
VLALPSEGYIAEQLDVVDPQRVHAVREAMRQQLAVALQADWEWTWEQHHDTGAYRPDAISSGRRALAGMALSMLCLAARR
TGDAVWPGKAYQRFKDAGNMTDRFNALTALVASGQPLAAQALARFHAMFKDEALVLDKWFSLQAGAPDRGGDVLPAVKQL
MKHPDFSLKNPNRARSLIFSYCSANPGAFHRQDAAGYAFWADRVIELDALNPQVAARLARALDRWSKLAEPYRTAARDAI
ARVAAKPDLSNDVREVVGRALAD
>Mature_903_residues
MREGQPATAIHRADYTAPAFWIDSVDLTFDLDPAKTRVLSRLRVRRNADVPPAPLRLDGEELNLARVLVNGAGTSFKLEG
SQLVLENLPEGHEPFDLEIFTTCCPAKNTQLSGLYVSQGTFFTQCEAEGFRRITYFLDRPDVMASYTVTLRADKAEYPVL
LSNGNLVDQGLLDDGRHFARWVDPHKKPCYLFALVAGKLVAREQRIRARSGNDHLLQIFVRPGDLEKTEHAMNSLMASIA
WDEARFGLPLDLERFMIVATSDFNMGAMENKGLNIFNTKYVLASQSTATDADFGNIESVVGHEYFHNWTGNRVTCRDWFQ
LSLKEGLTVFRDQEFSQDLSGSPSARAVKRIEDVRVLRTVQFPEDAGPMAHPVRPDSYVEINNFYTVTIYEKGAEVVRMM
HTLVGRDGFAAGMKLYFERHDGQAVTCDDFAQAIADANPDSELARLLPQFKRWYAQAGTPRVRARGAYDAGARTYTLTLE
QSIAPTPGQPVKEPMVIPVALGLLGADGSALPLQLEGEAEAGGPDRTVVLTEPVHTYTFVNVPSEPVPSLLRGFSAPVLL
DIEATDAQLLALLAHDTDPFNRWEAGQRLALRIAIQAIGDTSLDVPADGVLQRELLPASFVAAMRDVLRHPALDAAFKEL
VLALPSEGYIAEQLDVVDPQRVHAVREAMRQQLAVALQADWEWTWEQHHDTGAYRPDAISSGRRALAGMALSMLCLAARR
TGDAVWPGKAYQRFKDAGNMTDRFNALTALVASGQPLAAQALARFHAMFKDEALVLDKWFSLQAGAPDRGGDVLPAVKQL
MKHPDFSLKNPNRARSLIFSYCSANPGAFHRQDAAGYAFWADRVIELDALNPQVAARLARALDRWSKLAEPYRTAARDAI
ARVAAKPDLSNDVREVVGRALAD

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI61742777, Length=332, Percent_Identity=25.3012048192771, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI61742775, Length=332, Percent_Identity=25.3012048192771, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI158937236, Length=373, Percent_Identity=25.201072386059, Blast_Score=107, Evalue=5e-23,
Organism=Homo sapiens, GI132814467, Length=351, Percent_Identity=25.3561253561254, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI310123622, Length=330, Percent_Identity=26.0606060606061, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI310133497, Length=330, Percent_Identity=26.0606060606061, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI4505029, Length=449, Percent_Identity=24.9443207126949, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI94818901, Length=325, Percent_Identity=24.6153846153846, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI94818891, Length=325, Percent_Identity=24.6153846153846, Blast_Score=87, Evalue=9e-17,
Organism=Homo sapiens, GI157266300, Length=359, Percent_Identity=23.9554317548747, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI40316915, Length=347, Percent_Identity=25.0720461095101, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI194306629, Length=316, Percent_Identity=22.7848101265823, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI11641261, Length=316, Percent_Identity=22.7848101265823, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI7019561, Length=371, Percent_Identity=23.7196765498652, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI194239713, Length=426, Percent_Identity=23.943661971831, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI1787163, Length=901, Percent_Identity=46.2819089900111, Blast_Score=748, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989071, Length=482, Percent_Identity=25.103734439834, Blast_Score=109, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71989076, Length=482, Percent_Identity=25.103734439834, Blast_Score=109, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17569221, Length=364, Percent_Identity=25.8241758241758, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI115533276, Length=473, Percent_Identity=24.5243128964059, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI115533278, Length=473, Percent_Identity=24.5243128964059, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193206928, Length=465, Percent_Identity=24.0860215053763, Blast_Score=94, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193206926, Length=465, Percent_Identity=24.0860215053763, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17569225, Length=372, Percent_Identity=25, Blast_Score=91, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71984353, Length=509, Percent_Identity=23.5756385068762, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71984339, Length=510, Percent_Identity=23.5294117647059, Blast_Score=76, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71990873, Length=313, Percent_Identity=23.961661341853, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565628, Length=310, Percent_Identity=25.1612903225806, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI9755335, Length=427, Percent_Identity=24.1217798594848, Blast_Score=104, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6321837, Length=447, Percent_Identity=22.8187919463087, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324283, Length=426, Percent_Identity=21.830985915493, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646518, Length=353, Percent_Identity=26.9121813031161, Blast_Score=117, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24646514, Length=353, Percent_Identity=26.9121813031161, Blast_Score=117, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24646516, Length=353, Percent_Identity=26.9121813031161, Blast_Score=117, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24655257, Length=344, Percent_Identity=28.4883720930233, Blast_Score=116, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24655252, Length=344, Percent_Identity=28.4883720930233, Blast_Score=116, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24655274, Length=318, Percent_Identity=29.2452830188679, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24655260, Length=318, Percent_Identity=29.2452830188679, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24655265, Length=318, Percent_Identity=29.2452830188679, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24655268, Length=318, Percent_Identity=29.2452830188679, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24651025, Length=357, Percent_Identity=27.1708683473389, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24651023, Length=357, Percent_Identity=27.1708683473389, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24651021, Length=357, Percent_Identity=27.1708683473389, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24646512, Length=340, Percent_Identity=24.1176470588235, Blast_Score=103, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24646510, Length=340, Percent_Identity=24.1176470588235, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24648786, Length=387, Percent_Identity=26.6149870801034, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24651016, Length=247, Percent_Identity=29.1497975708502, Blast_Score=96, Evalue=9e-20,
Organism=Drosophila melanogaster, GI21358341, Length=228, Percent_Identity=26.7543859649123, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221379089, Length=345, Percent_Identity=24.9275362318841, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI161078673, Length=397, Percent_Identity=24.1813602015113, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571901, Length=397, Percent_Identity=24.1813602015113, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571792, Length=383, Percent_Identity=25.5874673629243, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648790, Length=358, Percent_Identity=24.3016759776536, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650973, Length=355, Percent_Identity=24.7887323943662, Blast_Score=78, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550850, Length=355, Percent_Identity=24.7887323943662, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221330574, Length=284, Percent_Identity=26.056338028169, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 99789; Mature: 99789

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREGQPATAIHRADYTAPAFWIDSVDLTFDLDPAKTRVLSRLRVRRNADVPPAPLRLDGE
CCCCCCCCEEECCCCCCCEEEEECEEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEECCC
ELNLARVLVNGAGTSFKLEGSQLVLENLPEGHEPFDLEIFTTCCPAKNTQLSGLYVSQGT
CCCEEEEEEECCCCEEEECCCHHHHHCCCCCCCCCEEEEEEEECCCCCCEECEEEEECCC
FFTQCEAEGFRRITYFLDRPDVMASYTVTLRADKAEYPVLLSNGNLVDQGLLDDGRHFAR
EEEEECCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCEEECCCCEECCCCCCCCHHHHH
WVDPHKKPCYLFALVAGKLVAREQRIRARSGNDHLLQIFVRPGDLEKTEHAMNSLMASIA
HCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
WDEARFGLPLDLERFMIVATSDFNMGAMENKGLNIFNTKYVLASQSTATDADFGNIESVV
HHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEECEEEEEECCCCCCCCCCCHHHHH
GHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSQDLSGSPSARAVKRIEDVRVLRTV
HHHHHHCCCCCEEEEHHHHHHHHHCCCCEECCCHHHHCCCCCCHHHHHHHHHHHHHHHEE
QFPEDAGPMAHPVRPDSYVEINNFYTVTIYEKGAEVVRMMHTLVGRDGFAAGMKLYFERH
CCCCCCCCCCCCCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHCCCCHHHCEEEEEEEC
DGQAVTCDDFAQAIADANPDSELARLLPQFKRWYAQAGTPRVRARGAYDAGARTYTLTLE
CCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEEEE
QSIAPTPGQPVKEPMVIPVALGLLGADGSALPLQLEGEAEAGGPDRTVVLTEPVHTYTFV
CCCCCCCCCCCCCCEEEEEEHEEECCCCCCCEEEECCCCCCCCCCCEEEEECCCEEEEEE
NVPSEPVPSLLRGFSAPVLLDIEATDAQLLALLAHDTDPFNRWEAGQRLALRIAIQAIGD
ECCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHCCCEEEEEEEEHHCC
TSLDVPADGVLQRELLPASFVAAMRDVLRHPALDAAFKELVLALPSEGYIAEQLDVVDPQ
CCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHCCCCHH
RVHAVREAMRQQLAVALQADWEWTWEQHHDTGAYRPDAISSGRRALAGMALSMLCLAARR
HHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
TGDAVWPGKAYQRFKDAGNMTDRFNALTALVASGQPLAAQALARFHAMFKDEALVLDKWF
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEHHH
SLQAGAPDRGGDVLPAVKQLMKHPDFSLKNPNRARSLIFSYCSANPGAFHRQDAAGYAFW
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEH
ADRVIELDALNPQVAARLARALDRWSKLAEPYRTAARDAIARVAAKPDLSNDVREVVGRA
HCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LAD
HCC
>Mature Secondary Structure
MREGQPATAIHRADYTAPAFWIDSVDLTFDLDPAKTRVLSRLRVRRNADVPPAPLRLDGE
CCCCCCCCEEECCCCCCCEEEEECEEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEECCC
ELNLARVLVNGAGTSFKLEGSQLVLENLPEGHEPFDLEIFTTCCPAKNTQLSGLYVSQGT
CCCEEEEEEECCCCEEEECCCHHHHHCCCCCCCCCEEEEEEEECCCCCCEECEEEEECCC
FFTQCEAEGFRRITYFLDRPDVMASYTVTLRADKAEYPVLLSNGNLVDQGLLDDGRHFAR
EEEEECCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCEEECCCCEECCCCCCCCHHHHH
WVDPHKKPCYLFALVAGKLVAREQRIRARSGNDHLLQIFVRPGDLEKTEHAMNSLMASIA
HCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
WDEARFGLPLDLERFMIVATSDFNMGAMENKGLNIFNTKYVLASQSTATDADFGNIESVV
HHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEECEEEEEECCCCCCCCCCCHHHHH
GHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSQDLSGSPSARAVKRIEDVRVLRTV
HHHHHHCCCCCEEEEHHHHHHHHHCCCCEECCCHHHHCCCCCCHHHHHHHHHHHHHHHEE
QFPEDAGPMAHPVRPDSYVEINNFYTVTIYEKGAEVVRMMHTLVGRDGFAAGMKLYFERH
CCCCCCCCCCCCCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHCCCCHHHCEEEEEEEC
DGQAVTCDDFAQAIADANPDSELARLLPQFKRWYAQAGTPRVRARGAYDAGARTYTLTLE
CCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEEEE
QSIAPTPGQPVKEPMVIPVALGLLGADGSALPLQLEGEAEAGGPDRTVVLTEPVHTYTFV
CCCCCCCCCCCCCCEEEEEEHEEECCCCCCCEEEECCCCCCCCCCCEEEEECCCEEEEEE
NVPSEPVPSLLRGFSAPVLLDIEATDAQLLALLAHDTDPFNRWEAGQRLALRIAIQAIGD
ECCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHCCCEEEEEEEEHHCC
TSLDVPADGVLQRELLPASFVAAMRDVLRHPALDAAFKELVLALPSEGYIAEQLDVVDPQ
CCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHCCCCHH
RVHAVREAMRQQLAVALQADWEWTWEQHHDTGAYRPDAISSGRRALAGMALSMLCLAARR
HHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
TGDAVWPGKAYQRFKDAGNMTDRFNALTALVASGQPLAAQALARFHAMFKDEALVLDKWF
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEHHH
SLQAGAPDRGGDVLPAVKQLMKHPDFSLKNPNRARSLIFSYCSANPGAFHRQDAAGYAFW
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEH
ADRVIELDALNPQVAARLARALDRWSKLAEPYRTAARDAIARVAAKPDLSNDVREVVGRA
HCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LAD
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]