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The map label for this gene is dam [C]

Identifier: 120610321

GI number: 120610321

Start: 1798144

End: 1798938

Strand: Direct

Name: dam [C]

Synonym: Aave_1638

Alternate gene names: 120610321

Gene position: 1798144-1798938 (Clockwise)

Preceding gene: 120610320

Following gene: 120610322

Centisome position: 33.59

GC content: 62.26

Gene sequence:

>795_bases
ATGGCAATGCCAATCATCCCCTGGCTTGGCGGCAAACGACGCCTGGCTGACATCATCATCCCGCGCTTTCCCGCGCACAC
CTGTTACGTGGAGGTTTTCGCCGGCGGCGCCGCGTTGTATTTCATGCGTCCGCCGGCGCAGGTGGAAGTCATCAACGACA
TCAACGGCGAGCTGGTCAACCTCTATCGCGTGGTCCAGCGGCACCTCGAGGAGTTTGTCCGCCAATTCAAGTGGGCGCTG
AGCAGTCGCGAGGTTTTTAGGTGGATGCAGATCACCGAGCCAGAGACGCTCACCGACATCGAGCGCGCGGCGCGGTTTTA
CTACTTGCAGAACCAGGCGTTTGGAGGCCGGGTGGAGGGCCAGACCTGGGGGACAGCGACGACAGCACCCGCACCCACCG
TCAACTTGCTTCGACTCGAGGAGACCCTCAGCGCGGCACATCTGCGGCTTCATGGTGCCTACATCGAGCGGCTGGACTGG
CAGGCGTGCGTCAGGCGCTATGACCGCTCGCACACCCTGTTTTACCTGGACCCTCCGTACTGGCAAACGGAGGGGTATGG
TGTGCCGTTCGCGTGGGCCGAATACGAGAGCATGGCGGTTGCGATGCGCTCGATAAAGGGGAAGGCTGTCCTGAGCATCA
ACGACCATCCCGACATCCGCAAGTGCTTCGCCGGCCTGCAGATGGAGGAGGTGCCGATCACTTACCAGGTGGGAGGTGGT
GGCAAGGGCGTGGACCGCACAGAACTCGTGATCTACAGCTGGGATCGGGACGCCGAGCACCCGGGCCTTTTCTGA

Upstream 100 bases:

>100_bases
CCTGACGGCCACCAGACACACAGAACCAGCCTGTGAGCCCAGCCAAGGCCCCGCCCACCTGTACAGGCGGGGGCGAGTGT
ATCAACCCCTGGAGCCCACT

Downstream 100 bases:

>100_bases
CGCGCAGCGATCGCCTGGCGAAAAGTGCTTGACGCTCTTTGGTGTGCGCCTAAAATTAGGCGCATGGGCAAGGCAATCGG
GCCGGCCTAAATGCCAGAAA

Product: D12 class N6 adenine-specific DNA methyltransferase

Products: S-adenosyl-L-homocysteine; DNA methylaminopurine [C]

Alternate protein names: DNA Adenine Methylase; Methyltransferase; Adenine-Specific DNA Methyltransferase; Site-Specific DNA-Methyltransferase; Site-Specific DNA Methylase; N6 Adenine-Specific DNA Methyltransferase; Methylase; Methylase LlaDCHIA; Adenine-Specific DNA-Methyltransferase; DNA Adenine Methyltransferase; Adenine Specific DNA Methyltransferase; N6 Adenine-Specific DNA Methyltransferase Protein; Phage DNA Adenine Methylase; Type II DNA Methyltransferase; Prophage; DNA Adenine Methylase Subfamily; Phage Associated Type II DNA-Methyltransferase; Ype IIs Methyltransferase M.AlwI; Phage-Related Methylase; Prophage DNA Adenine Methylase; Adenine-Specific Methyltransferase; Phage Methylase; DNA Methyltransferase; DNA Methylase; Phage_related Methylase; Prophage DNA Methylase; Type IIs Methyltransferase; LOW QUALITY PROTEIN DNA Adenine Methylase; Phage DNA Methyltransferase; Dam Methylase; Site-Specific DNA Methylase Protein

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MAMPIIPWLGGKRRLADIIIPRFPAHTCYVEVFAGGAALYFMRPPAQVEVINDINGELVNLYRVVQRHLEEFVRQFKWAL
SSREVFRWMQITEPETLTDIERAARFYYLQNQAFGGRVEGQTWGTATTAPAPTVNLLRLEETLSAAHLRLHGAYIERLDW
QACVRRYDRSHTLFYLDPPYWQTEGYGVPFAWAEYESMAVAMRSIKGKAVLSINDHPDIRKCFAGLQMEEVPITYQVGGG
GKGVDRTELVIYSWDRDAEHPGLF

Sequences:

>Translated_264_residues
MAMPIIPWLGGKRRLADIIIPRFPAHTCYVEVFAGGAALYFMRPPAQVEVINDINGELVNLYRVVQRHLEEFVRQFKWAL
SSREVFRWMQITEPETLTDIERAARFYYLQNQAFGGRVEGQTWGTATTAPAPTVNLLRLEETLSAAHLRLHGAYIERLDW
QACVRRYDRSHTLFYLDPPYWQTEGYGVPFAWAEYESMAVAMRSIKGKAVLSINDHPDIRKCFAGLQMEEVPITYQVGGG
GKGVDRTELVIYSWDRDAEHPGLF
>Mature_263_residues
AMPIIPWLGGKRRLADIIIPRFPAHTCYVEVFAGGAALYFMRPPAQVEVINDINGELVNLYRVVQRHLEEFVRQFKWALS
SREVFRWMQITEPETLTDIERAARFYYLQNQAFGGRVEGQTWGTATTAPAPTVNLLRLEETLSAAHLRLHGAYIERLDWQ
ACVRRYDRSHTLFYLDPPYWQTEGYGVPFAWAEYESMAVAMRSIKGKAVLSINDHPDIRKCFAGLQMEEVPITYQVGGGG
KGVDRTELVIYSWDRDAEHPGLF

Specific function: Methylates DNA Within The Sequence GATC And Protects The DNA From Cleavage By The Restriction Endonuclease Mboi. Although It Shares Sequence Specificity With A Number Of Type II Restriction Endonucleases And Methylases, It Is Thought To Act In Postreplica

COG id: COG0338

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.72 [C]

Molecular weight: Translated: 30288; Mature: 30157

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMPIIPWLGGKRRLADIIIPRFPAHTCYVEVFAGGAALYFMRPPAQVEVINDINGELVN
CCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEEECCEEEEEECCCCEEEEECCCCHHHHH
LYRVVQRHLEEFVRQFKWALSSREVFRWMQITEPETLTDIERAARFYYLQNQAFGGRVEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEEECCCCCCEECC
QTWGTATTAPAPTVNLLRLEETLSAAHLRLHGAYIERLDWQACVRRYDRSHTLFYLDPPY
CCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCC
WQTEGYGVPFAWAEYESMAVAMRSIKGKAVLSINDHPDIRKCFAGLQMEEVPITYQVGGG
CCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCEEECCCEEEEECCC
GKGVDRTELVIYSWDRDAEHPGLF
CCCCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
AMPIIPWLGGKRRLADIIIPRFPAHTCYVEVFAGGAALYFMRPPAQVEVINDINGELVN
CCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEEECCEEEEEECCCCEEEEECCCCHHHHH
LYRVVQRHLEEFVRQFKWALSSREVFRWMQITEPETLTDIERAARFYYLQNQAFGGRVEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEEECCCCCCEECC
QTWGTATTAPAPTVNLLRLEETLSAAHLRLHGAYIERLDWQACVRRYDRSHTLFYLDPPY
CCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCC
WQTEGYGVPFAWAEYESMAVAMRSIKGKAVLSINDHPDIRKCFAGLQMEEVPITYQVGGG
CCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCEEECCCEEEEECCC
GKGVDRTELVIYSWDRDAEHPGLF
CCCCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; DNA adenine; DNA [C]

Specific reaction: S-Adenosyl-L-methionine + DNA adenine =S-adenosyl-L-homocysteine + DNA methylaminopurine Protein + DNA = Protein-DNA [C]

General reaction: Methyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA