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The map label for this gene is yajO [H]

Identifier: 120610250

GI number: 120610250

Start: 1730861

End: 1731859

Strand: Direct

Name: yajO [H]

Synonym: Aave_1565

Alternate gene names: 120610250

Gene position: 1730861-1731859 (Clockwise)

Preceding gene: 120610249

Following gene: 120610251

Centisome position: 32.34

GC content: 71.17

Gene sequence:

>999_bases
ATGCAATACCGCCGCCTCGGCCGCAGCAACCTGCAGGTTTCCGCCCTCTGCCTGGGCACCATGATGTTCGGCGACCAGAC
CGGCCGGGACGAGGCCGCGGCCATCGTGGCCGATGCGCGGGAGCGCGGCGTGAATTTCATCGACACGGCGGACGTCTATA
CCAGGGGCGCCTCCGAATCGATGCTGGGCGACCTGCTGGCGGGCCAGCGGCACGACTGGGTGCTGGCCACCAAGCTGGGC
AACCGGATGTCCGACCGCGTGAACGAGAGCCACTATTCCCGCACCTGGATGCTGCGCGAGGTGGAGGCCAGCCTGGCGCG
CCTGCGCACCGACCATGTGGACATCCTCTACCTGCACCGCGATTTCCTGGGCATGGACCTCGAGGAGCCGCTCTTCGCCC
TCGATGCGCTGCTGCGCGCGGGCAAGATCCGCTACTGGGGCGTCTCCAACTTCCGCGCGTGGCGCATCGCCGAGCTGGTG
CACGGCGCCGCGCGCATCGGCATGCCCGGGCCCGTGGTCTGCCAGCCCTACTACAACCTGCTCAACCGTATGCCGGAGGT
CGAGATCCTGCCGGCCTGCGCGCACCACGGCCTGGGCGTGGTGCCCTACAGCCCCATCGCGCGCGGCGTGCTCACCGGCA
AGTACCTGCCGGGCGAGGCGCCGGCGGCGGGCACGCGCGCCGGGCGGGGCGACAGGCGCATCGCGGAAACCGAATTCCGC
CACGAATCGCTGGTGCTGGCGCAGGAGCTGAAGCGGCACGCCGAGGCCCGCGGCGTGACGCTGGCCCAGTTCGCCACCGC
CTGGGTATTGGCCCACCGGGCGGTCAGCGCCGTCATCGCGGGCCCGCGCACCCTGGCCCAGTGGCAGGACTACGCACCTG
CGCTCGAATACACCGTCACGCCGGAAGACGAAGCCCTGGTGGATGGCATGGTGGCGCCGGGCCACCCCTCCACGCCGGGC
TACACCGACCCGGCCTATCCCGCACCGCCGCGCGTTTAG

Upstream 100 bases:

>100_bases
CCGTCGCGCGGCGGCCTTGCATTGGGCCGTGGCGGTGAGGCGCCTCTTCTCGATATTCCCCGCGCCCTTCGGGCGCCTCA
TTCACTGAAAGGCCCGCCCC

Downstream 100 bases:

>100_bases
AGCCGCGCCGGGCCACCGCGAAGCTTTTCCATCCGTCGCGCGTTGCTATTGAAATCATAGTGCCCGGGCGCGGGCAGGTT
ACGATGGGCGCATGCGAAAG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MQYRRLGRSNLQVSALCLGTMMFGDQTGRDEAAAIVADARERGVNFIDTADVYTRGASESMLGDLLAGQRHDWVLATKLG
NRMSDRVNESHYSRTWMLREVEASLARLRTDHVDILYLHRDFLGMDLEEPLFALDALLRAGKIRYWGVSNFRAWRIAELV
HGAARIGMPGPVVCQPYYNLLNRMPEVEILPACAHHGLGVVPYSPIARGVLTGKYLPGEAPAAGTRAGRGDRRIAETEFR
HESLVLAQELKRHAEARGVTLAQFATAWVLAHRAVSAVIAGPRTLAQWQDYAPALEYTVTPEDEALVDGMVAPGHPSTPG
YTDPAYPAPPRV

Sequences:

>Translated_332_residues
MQYRRLGRSNLQVSALCLGTMMFGDQTGRDEAAAIVADARERGVNFIDTADVYTRGASESMLGDLLAGQRHDWVLATKLG
NRMSDRVNESHYSRTWMLREVEASLARLRTDHVDILYLHRDFLGMDLEEPLFALDALLRAGKIRYWGVSNFRAWRIAELV
HGAARIGMPGPVVCQPYYNLLNRMPEVEILPACAHHGLGVVPYSPIARGVLTGKYLPGEAPAAGTRAGRGDRRIAETEFR
HESLVLAQELKRHAEARGVTLAQFATAWVLAHRAVSAVIAGPRTLAQWQDYAPALEYTVTPEDEALVDGMVAPGHPSTPG
YTDPAYPAPPRV
>Mature_332_residues
MQYRRLGRSNLQVSALCLGTMMFGDQTGRDEAAAIVADARERGVNFIDTADVYTRGASESMLGDLLAGQRHDWVLATKLG
NRMSDRVNESHYSRTWMLREVEASLARLRTDHVDILYLHRDFLGMDLEEPLFALDALLRAGKIRYWGVSNFRAWRIAELV
HGAARIGMPGPVVCQPYYNLLNRMPEVEILPACAHHGLGVVPYSPIARGVLTGKYLPGEAPAAGTRAGRGDRRIAETEFR
HESLVLAQELKRHAEARGVTLAQFATAWVLAHRAVSAVIAGPRTLAQWQDYAPALEYTVTPEDEALVDGMVAPGHPSTPG
YTDPAYPAPPRV

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=298, Percent_Identity=35.2348993288591, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI27436962, Length=298, Percent_Identity=35.2348993288591, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI27436966, Length=298, Percent_Identity=34.8993288590604, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI27436969, Length=310, Percent_Identity=32.258064516129, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI27436971, Length=325, Percent_Identity=32, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI4504825, Length=308, Percent_Identity=32.1428571428571, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI223718702, Length=333, Percent_Identity=30.6306306306306, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI41327764, Length=317, Percent_Identity=31.2302839116719, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI41152114, Length=334, Percent_Identity=29.6407185628743, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI223718708, Length=178, Percent_Identity=32.5842696629214, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87081735, Length=326, Percent_Identity=35.8895705521472, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789375, Length=324, Percent_Identity=31.1728395061728, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789199, Length=342, Percent_Identity=30.9941520467836, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788081, Length=334, Percent_Identity=28.7425149700599, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788070, Length=339, Percent_Identity=28.6135693215339, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787674, Length=316, Percent_Identity=23.7341772151899, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=173, Percent_Identity=29.4797687861272, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=326, Percent_Identity=28.2208588957055, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323998, Length=340, Percent_Identity=27.3529411764706, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=315, Percent_Identity=26.031746031746, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=322, Percent_Identity=25.4658385093168, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322615, Length=235, Percent_Identity=27.6595744680851, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646159, Length=223, Percent_Identity=31.8385650224215, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45549126, Length=322, Percent_Identity=25.4658385093168, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640980, Length=322, Percent_Identity=25.4658385093168, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646155, Length=220, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36622; Mature: 36622

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYRRLGRSNLQVSALCLGTMMFGDQTGRDEAAAIVADARERGVNFIDTADVYTRGASES
CCCHHCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECHHHHHCCCCHH
MLGDLLAGQRHDWVLATKLGNRMSDRVNESHYSRTWMLREVEASLARLRTDHVDILYLHR
HHHHHHCCCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEH
DFLGMDLEEPLFALDALLRAGKIRYWGVSNFRAWRIAELVHGAARIGMPGPVVCQPYYNL
HHHCCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEECHHHHH
LNRMPEVEILPACAHHGLGVVPYSPIARGVLTGKYLPGEAPAAGTRAGRGDRRIAETEFR
HHCCCCCEEEHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
HESLVLAQELKRHAEARGVTLAQFATAWVLAHRAVSAVIAGPRTLAQWQDYAPALEYTVT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEC
PEDEALVDGMVAPGHPSTPGYTDPAYPAPPRV
CCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQYRRLGRSNLQVSALCLGTMMFGDQTGRDEAAAIVADARERGVNFIDTADVYTRGASES
CCCHHCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECHHHHHCCCCHH
MLGDLLAGQRHDWVLATKLGNRMSDRVNESHYSRTWMLREVEASLARLRTDHVDILYLHR
HHHHHHCCCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEH
DFLGMDLEEPLFALDALLRAGKIRYWGVSNFRAWRIAELVHGAARIGMPGPVVCQPYYNL
HHHCCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEECHHHHH
LNRMPEVEILPACAHHGLGVVPYSPIARGVLTGKYLPGEAPAAGTRAGRGDRRIAETEFR
HHCCCCCEEEHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
HESLVLAQELKRHAEARGVTLAQFATAWVLAHRAVSAVIAGPRTLAQWQDYAPALEYTVT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEC
PEDEALVDGMVAPGHPSTPGYTDPAYPAPPRV
CCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]