Click here to switch to the map view.

The map label for this gene is paaK [H]

Identifier: 120609475

GI number: 120609475

Start: 838507

End: 839784

Strand: Reverse

Name: paaK [H]

Synonym: Aave_0781

Alternate gene names: 120609475

Gene position: 839784-838507 (Counterclockwise)

Preceding gene: 120609476

Following gene: 120609474

Centisome position: 15.69

GC content: 74.18

Gene sequence:

>1278_bases
TTGCACAACCGCATGGATGAAGGCATGAGCATGATGGATTCCTACGACGCCCTCGAAACCCGCGCGCCCGAGGAGCGCGA
GGCTGCGCTGATGGCGGCGCTGCCGGCGCAGGTGGCGCATGCGCGGTCGGCCACGGCGGCTTTCGGCGAGATCCTGGCGG
GGGTGGATCCGCGGGCCGTGACCAGCCGGGACGCGCTGGCCGCCCTGCCGGTGACGCGCAAGCACGAGCTGCTGGAGCGG
CAGCAGGCGGGCCGCGCCGCGAACCCGTTCGGGGGCTTCAGCGCGCTGGCATTCGGCCCGGCGATGCCGCGCGTGTTCGC
GAGCCCGGGCACGCTCTACGAGCCGGAAGGCCGGCGGGCGGACTATTGGCGCATGGCGCGCGCGATCCATGCCGCGGGAT
TCCGGCCCGGCGAGCTGGTCCACAACTGCTTCAGCTACCACTTCGTGCCCGCGGGCGCCATGATGGAAGGCGGGGCGCAG
GCCCTGGGCTGCACGGTGTTCGCGGGCGGCACGGGGCAGACGGAGCAGCAGGTGCAGGCCATGGCCGAGCTGCGCCCCGC
GGGCTATATCGGCACGCCGAGCTTCCTGCGCATCCTGCTGGAGAAGGCGGCGGAGACGGGCACGGCACTGCCGCACCTGG
GCAAGGCGCTGGTGTCGGGCGAGGCGCTGCCGCCCTCGCTGCGCGACTGGTTCGCCGGGCGCGGCGTCGCGGCCTACCAG
TGCTATGCCACGGCGGACCTGGGCCTGATCGCCTACGAGACCCGCGCCCGCGAGGGCCTGGTACTGGGCGAGGACGTGAT
CGTGGAGATCGTGCGGCCCGGCACCGGCGACCCGGTGCCCGACGGCGAGGTGGGCGAAGTGGTGGTGACCACGCTCAACC
CCGACTACCCCCTGGTGCGCTTCGGCACGGGCGACCTGTCGGCCGTGCTGCCCGGCCCCTGTCCCACCGGCCGCACGAAC
CGCCGCATCCGCGGCTGGATGGGCCGGGCCGACCAGACCACCAAGGTGCGCGGCATGTTCGTGCACCCCGGCCAGGTGGC
CGAGGTGGCGCGGCGCTTCCCGCAGGTGGGGCGCGCGCGCCTCGTCGTGGGCGGCGAGATGGCCAGCGACACCCTGGTGC
TGCGCGTGGAAACGCCGGAGACCGCCGGCGGGCTGGCCGACCAGCTGGCGGCCGCGGTGCGCGAGGTCACCAAGCTGCGC
GCCGAGGTGGAGATGCTGCCGCCGGGGAGCCTGCCCAACGACGGCCGCGTGATCGAGGATGCGCGCAGCTACCGGTGA

Upstream 100 bases:

>100_bases
CGATAGGTGGCGCTGCGCCTGTTCATGGGCAATGAGCTACAGGCAAATATGGGTGGCGGGGACATGTACATAGTTCCGCC
GCTGATGGTTACGACATGGA

Downstream 100 bases:

>100_bases
CCGCGGGAGCACGCATGCCACAGCTGGATTGCATGGGGCTTACACTCCTATTTCCATAGCAACGAATCCATTCAAGTCAA
TGGACCCAGCGCAAAAAAAC

Product: putative phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MHNRMDEGMSMMDSYDALETRAPEEREAALMAALPAQVAHARSATAAFGEILAGVDPRAVTSRDALAALPVTRKHELLER
QQAGRAANPFGGFSALAFGPAMPRVFASPGTLYEPEGRRADYWRMARAIHAAGFRPGELVHNCFSYHFVPAGAMMEGGAQ
ALGCTVFAGGTGQTEQQVQAMAELRPAGYIGTPSFLRILLEKAAETGTALPHLGKALVSGEALPPSLRDWFAGRGVAAYQ
CYATADLGLIAYETRAREGLVLGEDVIVEIVRPGTGDPVPDGEVGEVVVTTLNPDYPLVRFGTGDLSAVLPGPCPTGRTN
RRIRGWMGRADQTTKVRGMFVHPGQVAEVARRFPQVGRARLVVGGEMASDTLVLRVETPETAGGLADQLAAAVREVTKLR
AEVEMLPPGSLPNDGRVIEDARSYR

Sequences:

>Translated_425_residues
MHNRMDEGMSMMDSYDALETRAPEEREAALMAALPAQVAHARSATAAFGEILAGVDPRAVTSRDALAALPVTRKHELLER
QQAGRAANPFGGFSALAFGPAMPRVFASPGTLYEPEGRRADYWRMARAIHAAGFRPGELVHNCFSYHFVPAGAMMEGGAQ
ALGCTVFAGGTGQTEQQVQAMAELRPAGYIGTPSFLRILLEKAAETGTALPHLGKALVSGEALPPSLRDWFAGRGVAAYQ
CYATADLGLIAYETRAREGLVLGEDVIVEIVRPGTGDPVPDGEVGEVVVTTLNPDYPLVRFGTGDLSAVLPGPCPTGRTN
RRIRGWMGRADQTTKVRGMFVHPGQVAEVARRFPQVGRARLVVGGEMASDTLVLRVETPETAGGLADQLAAAVREVTKLR
AEVEMLPPGSLPNDGRVIEDARSYR
>Mature_425_residues
MHNRMDEGMSMMDSYDALETRAPEEREAALMAALPAQVAHARSATAAFGEILAGVDPRAVTSRDALAALPVTRKHELLER
QQAGRAANPFGGFSALAFGPAMPRVFASPGTLYEPEGRRADYWRMARAIHAAGFRPGELVHNCFSYHFVPAGAMMEGGAQ
ALGCTVFAGGTGQTEQQVQAMAELRPAGYIGTPSFLRILLEKAAETGTALPHLGKALVSGEALPPSLRDWFAGRGVAAYQ
CYATADLGLIAYETRAREGLVLGEDVIVEIVRPGTGDPVPDGEVGEVVVTTLNPDYPLVRFGTGDLSAVLPGPCPTGRTN
RRIRGWMGRADQTTKVRGMFVHPGQVAEVARRFPQVGRARLVVGGEMASDTLVLRVETPETAGGLADQLAAAVREVTKLR
AEVEMLPPGSLPNDGRVIEDARSYR

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=424, Percent_Identity=27.8301886792453, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 45327; Mature: 45327

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNRMDEGMSMMDSYDALETRAPEEREAALMAALPAQVAHARSATAAFGEILAGVDPRAV
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TSRDALAALPVTRKHELLERQQAGRAANPFGGFSALAFGPAMPRVFASPGTLYEPEGRRA
CCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCHHHCCCCCEECCCCCCH
DYWRMARAIHAAGFRPGELVHNCFSYHFVPAGAMMEGGAQALGCTVFAGGTGQTEQQVQA
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEEEECCCCCHHHHHHH
MAELRPAGYIGTPSFLRILLEKAAETGTALPHLGKALVSGEALPPSLRDWFAGRGVAAYQ
HHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEE
CYATADLGLIAYETRAREGLVLGEDVIVEIVRPGTGDPVPDGEVGEVVVTTLNPDYPLVR
EEEECCCCEEEEECCCCCCEEECCHHHEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEE
FGTGDLSAVLPGPCPTGRTNRRIRGWMGRADQTTKVRGMFVHPGQVAEVARRFPQVGRAR
ECCCCCCEECCCCCCCCCCCCHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCEE
LVVGGEMASDTLVLRVETPETAGGLADQLAAAVREVTKLRAEVEMLPPGSLPNDGRVIED
EEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHH
ARSYR
HHCCC
>Mature Secondary Structure
MHNRMDEGMSMMDSYDALETRAPEEREAALMAALPAQVAHARSATAAFGEILAGVDPRAV
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TSRDALAALPVTRKHELLERQQAGRAANPFGGFSALAFGPAMPRVFASPGTLYEPEGRRA
CCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCHHHCCCCCEECCCCCCH
DYWRMARAIHAAGFRPGELVHNCFSYHFVPAGAMMEGGAQALGCTVFAGGTGQTEQQVQA
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEEEECCCCCHHHHHHH
MAELRPAGYIGTPSFLRILLEKAAETGTALPHLGKALVSGEALPPSLRDWFAGRGVAAYQ
HHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEE
CYATADLGLIAYETRAREGLVLGEDVIVEIVRPGTGDPVPDGEVGEVVVTTLNPDYPLVR
EEEECCCCEEEEECCCCCCEEECCHHHEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEE
FGTGDLSAVLPGPCPTGRTNRRIRGWMGRADQTTKVRGMFVHPGQVAEVARRFPQVGRAR
ECCCCCCEECCCCCCCCCCCCHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCEE
LVVGGEMASDTLVLRVETPETAGGLADQLAAAVREVTKLRAEVEMLPPGSLPNDGRVIED
EEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHH
ARSYR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]