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The map label for this gene is mdtI [H]

Identifier: 120609417

GI number: 120609417

Start: 776117

End: 776359

Strand: Direct

Name: mdtI [H]

Synonym: Aave_0721

Alternate gene names: 120609417

Gene position: 776117-776359 (Clockwise)

Preceding gene: 120609416

Following gene: 120609418

Centisome position: 14.5

GC content: 58.85

Gene sequence:

>243_bases
ATGCTCCGGAGCCGCCGGGTGCCGGGAATTATCGGGATCTTTTGCATCCTGGCGTCTTTTACAGCCTTAGCGCAGGCAGT
CAAGGGCATCGACCTATCAATCGCCTACGCCTTGTGGGGGGGCACCGGCATCGTGCTGACCAGCATGGCGGGATGGGCGT
TGTTTCGGCAAAGGCTGGGCCGCCAAGCCTTTGCAGGAATCTTGCTGATCGTAGCCGGCATATCACTACTCAAGCTCTCT
TGA

Upstream 100 bases:

>100_bases
GTCACGCTCAACCCTGAGCGCGACGGCATCTCCAATGCCGCGGCGACCGCATCGAATACGCAGCCTCGGGCTGCTTGATC
GACGCGACAACTACCTTGAC

Downstream 100 bases:

>100_bases
GTCAGGGTTGATGCCTTGCCACAAGGGCGCCCGGTCAGCGAATGAAGATGGAATGAGGGCTTCATGGAAATACGTCATCT
GCGCTGCTTTCTAGCTGTTG

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 80; Mature: 80

Protein sequence:

>80_residues
MLRSRRVPGIIGIFCILASFTALAQAVKGIDLSIAYALWGGTGIVLTSMAGWALFRQRLGRQAFAGILLIVAGISLLKLS

Sequences:

>Translated_80_residues
MLRSRRVPGIIGIFCILASFTALAQAVKGIDLSIAYALWGGTGIVLTSMAGWALFRQRLGRQAFAGILLIVAGISLLKLS
>Mature_80_residues
MLRSRRVPGIIGIFCILASFTALAQAVKGIDLSIAYALWGGTGIVLTSMAGWALFRQRLGRQAFAGILLIVAGISLLKLS

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787883, Length=76, Percent_Identity=53.9473684210526, Blast_Score=75, Evalue=6e-16,
Organism=Escherichia coli, GI1786755, Length=76, Percent_Identity=44.7368421052632, Blast_Score=62, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 8475; Mature: 8475

Theoretical pI: Translated: 12.22; Mature: 12.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRSRRVPGIIGIFCILASFTALAQAVKGIDLSIAYALWGGTGIVLTSMAGWALFRQRLG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
RQAFAGILLIVAGISLLKLS
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLRSRRVPGIIGIFCILASFTALAQAVKGIDLSIAYALWGGTGIVLTSMAGWALFRQRLG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
RQAFAGILLIVAGISLLKLS
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA