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The map label for this gene is cfr9IM [H]

Identifier: 120609261

GI number: 120609261

Start: 607126

End: 608097

Strand: Reverse

Name: cfr9IM [H]

Synonym: Aave_0560

Alternate gene names: 120609261

Gene position: 608097-607126 (Counterclockwise)

Preceding gene: 120609262

Following gene: 120609260

Centisome position: 11.36

GC content: 68.0

Gene sequence:

>972_bases
ATGCGGGAACAAGCCTCCCGGTGGCTGGACACGACGCATGCCGGCGACTGCCGCGTGCTGCTCAGTCGCATGCTTGCAGA
TGGCGTGCAGGTGCAGACCTGCATCACGAGCCCACCCTACTTCGGGCTGCGCTGCTACCTCCCGGACCACCATCCCGACA
AGCATCGGGAAATCGGCTGCGGCTCGACGCCCGAGCAGTACGTGGCCCAGTTGGTGGAGGTCTTCCAGATCGTGCGGCGT
CTGCTGGCCGATGACGGAACGCTGTGGATCGTGATCGGCGACAGCTACGCTGCCAACGGCGCCAGCGGACTCAACACCGG
CTGGGCCGAACGATCGCGGCGGTATGCCGGCGGAGGACGGCGAGCCGCACAGGCACGCAACCGCACGCGGAAATCCGTCC
CGGCCGGCCTGAAGGCCAAGGACCTGATCGGCGTGCCCTGGATGCTGGCCTTCGCCCTCCGCCGGGACGGATGGTATCTG
CGCCAGGAAGTGATCTGGCACAAGCCGAACCCGATGCCGGAGAGCGTGACCGACCGCTGCACACGCGCGCACGAATCCGT
GTTTCTTCTGTCGAAGCGGGCGCGCTACTACTTCGACGTGCAGGCGATAGCGGAGCCCGTCGCGCCGTCCACGGTCCTGC
GGCTTTCGCAGCCGCGGCTTGCGCAGCAGTCGGGCAGCACGCGCGTGCAGGGCAAGACGAACGGCAACATGCCGACCGTA
GGCTGCCTCGACATGCGTCGCCGCCGCAGCGTCTGGACCATCGCAACCAGAGCCAACAGGGGACCACACAACGCGACCTA
TCCGGCCGCGCTCATCGGCCCTTGCATCCTCGCCGGCAGCAGAGCCGGCGATGTCGTCCTGGACCCGTTCATGGGCAGCG
GCACCACCGGCACCACGGCTCTGCGGCTCCGGCGGCACTTCGTCGGCTGCGAGCTCGTTCGGTCGTACATCGACCCGACC
CACCTGCGCTGA

Upstream 100 bases:

>100_bases
TGGACTGCGCCAGCAAGATCGCCAGTGCCGAGACCGTTTACCTGCGCCGCAGGGCGCCTGAATCTGAGGGCCGCCAGCGC
GGCCGGGGGCCGGCGCCGTG

Downstream 100 bases:

>100_bases
CGTTCGCCGGCGCAGTTCCCACCACCACTACGGAGAAGACCATGAGCACCCATTTCCATGGCGAAGGCAACATCGGTTCG
CCACCGAAGTTCGACGAGTA

Product: DNA methylase N-4/N-6 domain-containing protein

Products: NA

Alternate protein names: M.Cfr9I; N(4)- cytosine-specific methyltransferase Cfr9I [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MREQASRWLDTTHAGDCRVLLSRMLADGVQVQTCITSPPYFGLRCYLPDHHPDKHREIGCGSTPEQYVAQLVEVFQIVRR
LLADDGTLWIVIGDSYAANGASGLNTGWAERSRRYAGGGRRAAQARNRTRKSVPAGLKAKDLIGVPWMLAFALRRDGWYL
RQEVIWHKPNPMPESVTDRCTRAHESVFLLSKRARYYFDVQAIAEPVAPSTVLRLSQPRLAQQSGSTRVQGKTNGNMPTV
GCLDMRRRRSVWTIATRANRGPHNATYPAALIGPCILAGSRAGDVVLDPFMGSGTTGTTALRLRRHFVGCELVRSYIDPT
HLR

Sequences:

>Translated_323_residues
MREQASRWLDTTHAGDCRVLLSRMLADGVQVQTCITSPPYFGLRCYLPDHHPDKHREIGCGSTPEQYVAQLVEVFQIVRR
LLADDGTLWIVIGDSYAANGASGLNTGWAERSRRYAGGGRRAAQARNRTRKSVPAGLKAKDLIGVPWMLAFALRRDGWYL
RQEVIWHKPNPMPESVTDRCTRAHESVFLLSKRARYYFDVQAIAEPVAPSTVLRLSQPRLAQQSGSTRVQGKTNGNMPTV
GCLDMRRRRSVWTIATRANRGPHNATYPAALIGPCILAGSRAGDVVLDPFMGSGTTGTTALRLRRHFVGCELVRSYIDPT
HLR
>Mature_323_residues
MREQASRWLDTTHAGDCRVLLSRMLADGVQVQTCITSPPYFGLRCYLPDHHPDKHREIGCGSTPEQYVAQLVEVFQIVRR
LLADDGTLWIVIGDSYAANGASGLNTGWAERSRRYAGGGRRAAQARNRTRKSVPAGLKAKDLIGVPWMLAFALRRDGWYL
RQEVIWHKPNPMPESVTDRCTRAHESVFLLSKRARYYFDVQAIAEPVAPSTVLRLSQPRLAQQSGSTRVQGKTNGNMPTV
GCLDMRRRRSVWTIATRANRGPHNATYPAALIGPCILAGSRAGDVVLDPFMGSGTTGTTALRLRRHFVGCELVRSYIDPT
HLR

Specific function: This methylase recognizes the double-stranded sequence CCCGGG, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the Cfr9I endonuclease [H]

COG id: COG0863

COG function: function code L; DNA modification methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002941
- InterPro:   IPR017985
- InterPro:   IPR001091 [H]

Pfam domain/function: PF01555 N6_N4_Mtase [H]

EC number: =2.1.1.113 [H]

Molecular weight: Translated: 35950; Mature: 35950

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: PS00093 N4_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREQASRWLDTTHAGDCRVLLSRMLADGVQVQTCITSPPYFGLRCYLPDHHPDKHREIGC
CCCHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCC
GSTPEQYVAQLVEVFQIVRRLLADDGTLWIVIGDSYAANGASGLNTGWAERSRRYAGGGR
CCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCH
RAAQARNRTRKSVPAGLKAKDLIGVPWMLAFALRRDGWYLRQEVIWHKPNPMPESVTDRC
HHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHCCCCEEHHHHHCCCCCCCCHHHHHHH
TRAHESVFLLSKRARYYFDVQAIAEPVAPSTVLRLSQPRLAQQSGSTRVQGKTNGNMPTV
HHHHHHHHHHHHCCHHEEEHHHHHCCCCCHHHHHCCCCHHHHHCCCCEEECCCCCCCCCC
GCLDMRRRRSVWTIATRANRGPHNATYPAALIGPCILAGSRAGDVVLDPFMGSGTTGTTA
HHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHH
LRLRRHFVGCELVRSYIDPTHLR
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MREQASRWLDTTHAGDCRVLLSRMLADGVQVQTCITSPPYFGLRCYLPDHHPDKHREIGC
CCCHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCC
GSTPEQYVAQLVEVFQIVRRLLADDGTLWIVIGDSYAANGASGLNTGWAERSRRYAGGGR
CCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCH
RAAQARNRTRKSVPAGLKAKDLIGVPWMLAFALRRDGWYLRQEVIWHKPNPMPESVTDRC
HHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHCCCCEEHHHHHCCCCCCCCHHHHHHH
TRAHESVFLLSKRARYYFDVQAIAEPVAPSTVLRLSQPRLAQQSGSTRVQGKTNGNMPTV
HHHHHHHHHHHHCCHHEEEHHHHHCCCCCHHHHHCCCCHHHHHCCCCEEECCCCCCCCCC
GCLDMRRRRSVWTIATRANRGPHNATYPAALIGPCILAGSRAGDVVLDPFMGSGTTGTTA
HHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHH
LRLRRHFVGCELVRSYIDPTHLR
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2690010; 8163180 [H]