Click here to switch to the map view.

The map label for this gene is mtrC [H]

Identifier: 120609092

GI number: 120609092

Start: 418782

End: 420086

Strand: Reverse

Name: mtrC [H]

Synonym: Aave_0389

Alternate gene names: 120609092

Gene position: 420086-418782 (Counterclockwise)

Preceding gene: 120609096

Following gene: 120609091

Centisome position: 7.85

GC content: 72.8

Gene sequence:

>1305_bases
ATGTACCGCTTGAGTGTCGAAACCGCCGTCTCCGCCGCCCCGCTCCGCCGCACAGCGCGGTCGGGGCTTTTCTGCCTGGC
CCTGCTCGCAGCCGCCACTCTGGCGGCCTGCGGCAAGTCCGGCGGGTCCGACCAGCAGGGCCAGGGCGGCACCCCTCCGC
CACCGCAGGTGGGCGTGGTGACCGTCTCGCCGGGGGACGTGGGCCTGGTGACGGAGCTTCCGGGCCGCCTGGAAGCATCG
CGGGTGGCCCAGGTCCGCGCCCGAGCGGCCGGCATCCTGCAAAAGCGGCTCTTCACGGAAGGCAGCGACGTCAAGGCGGG
CCAGCGCCTGTTCGCGATCGACGACGCGCCCTACCGCGCCTCGCTGGAAAGCGCCCAGGCGAGCGTCGCCCAGGCCGAAG
CCAATGTGGCCCAGGCCCGGGCCCTGGCCGAGCGCTACAAGCCACTGGTGGCCGTGAATGCCGTGAGCCGGCAGGAGTAC
GACAACGCGGTCGCGTCCCAGAAGACGGCCGAGGCCAACCTGGCGGCAGCGCGTGCATCCGTCACCACGGCCCGCATCAA
CCTGGGCTACGCGGCCGTGACGGCGCCCATCTCCGGCCGCATCGGCCGCGCGCTCGTCACCGAGGGCGCGCTGGTGGGCC
AGGGCGAGGCCACGCAGCTCGCGGTGATCCAGCAGATCGATCCGCTCTACGTCAACTTCACCCAGTCCGCCTCCGACGCC
CTGAAGCTCAAGGCCGGCCTCGCGAGCGGCAAGTACAAGCAGGCTGCAAAGGGCGCCGCCTCGGTCAGCGTGGTCATGGA
AGACGGCAGCGTGCATCCGCAGACGGGCAAGCTGCTGTTCACCGACCTGTCGGTGGACCCCACCAGCGGCCAGGTCACGC
TGCGCGCCGAAGTGCCCAATCCCGAACGGCAGCTGCTGCCCGGCCTGTACGTGCGCGTGCGCCTGGAGCAGGCCCAGGTG
GACAACGGTGTCCTGCTGCCCCAGCAGGCCGTGACGCGCTCCGCCAGGGGCGATACCGTCATGGTCGTGGGCCCGGACAA
CCACCTGGCGCCGCGCCCCGTGAAGCTCGGCCCGGCCCAGGGCACCAACTGGGTCGTGCTGGATGGCCTGAAGGCCGGCG
AGAAGGTCATGGTGGACGGCTTCCAGAAGCTGCCCCGCGGCAAGCCCGGCGACCCGATCGTGGTGCAGCCCGTGCCCTGG
CAGCCCGCCGGTGCCGCCCCCGCGGGCGGCGCATCGGCGCCCGCCGCCGGAGCTTCCGCCGCACAGGCCCCCGCCTCCAG
CGCCTCCGCCCCCGCGAAGCAGTAA

Upstream 100 bases:

>100_bases
TATGTATAATGCCCGCGAATTCAAGGGCTGCCGCATGGTTTTGACGTTGCTCAAGGTCCTGCGACAGCCTTTTCCCCTGC
GCCGATCCGGAAGGACTTCC

Downstream 100 bases:

>100_bases
CCCCCAGAACACGGAGCGCGGCACATGGCCAAGTTCTTCATCGAACGGCCCATCTTCGCATGGGTCATCACGATCTTCAT
CATGGTGATGGGGGGCCTCT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MYRLSVETAVSAAPLRRTARSGLFCLALLAAATLAACGKSGGSDQQGQGGTPPPPQVGVVTVSPGDVGLVTELPGRLEAS
RVAQVRARAAGILQKRLFTEGSDVKAGQRLFAIDDAPYRASLESAQASVAQAEANVAQARALAERYKPLVAVNAVSRQEY
DNAVASQKTAEANLAAARASVTTARINLGYAAVTAPISGRIGRALVTEGALVGQGEATQLAVIQQIDPLYVNFTQSASDA
LKLKAGLASGKYKQAAKGAASVSVVMEDGSVHPQTGKLLFTDLSVDPTSGQVTLRAEVPNPERQLLPGLYVRVRLEQAQV
DNGVLLPQQAVTRSARGDTVMVVGPDNHLAPRPVKLGPAQGTNWVVLDGLKAGEKVMVDGFQKLPRGKPGDPIVVQPVPW
QPAGAAPAGGASAPAAGASAAQAPASSASAPAKQ

Sequences:

>Translated_434_residues
MYRLSVETAVSAAPLRRTARSGLFCLALLAAATLAACGKSGGSDQQGQGGTPPPPQVGVVTVSPGDVGLVTELPGRLEAS
RVAQVRARAAGILQKRLFTEGSDVKAGQRLFAIDDAPYRASLESAQASVAQAEANVAQARALAERYKPLVAVNAVSRQEY
DNAVASQKTAEANLAAARASVTTARINLGYAAVTAPISGRIGRALVTEGALVGQGEATQLAVIQQIDPLYVNFTQSASDA
LKLKAGLASGKYKQAAKGAASVSVVMEDGSVHPQTGKLLFTDLSVDPTSGQVTLRAEVPNPERQLLPGLYVRVRLEQAQV
DNGVLLPQQAVTRSARGDTVMVVGPDNHLAPRPVKLGPAQGTNWVVLDGLKAGEKVMVDGFQKLPRGKPGDPIVVQPVPW
QPAGAAPAGGASAPAAGASAAQAPASSASAPAKQ
>Mature_434_residues
MYRLSVETAVSAAPLRRTARSGLFCLALLAAATLAACGKSGGSDQQGQGGTPPPPQVGVVTVSPGDVGLVTELPGRLEAS
RVAQVRARAAGILQKRLFTEGSDVKAGQRLFAIDDAPYRASLESAQASVAQAEANVAQARALAERYKPLVAVNAVSRQEY
DNAVASQKTAEANLAAARASVTTARINLGYAAVTAPISGRIGRALVTEGALVGQGEATQLAVIQQIDPLYVNFTQSASDA
LKLKAGLASGKYKQAAKGAASVSVVMEDGSVHPQTGKLLFTDLSVDPTSGQVTLRAEVPNPERQLLPGLYVRVRLEQAQV
DNGVLLPQQAVTRSARGDTVMVVGPDNHLAPRPVKLGPAQGTNWVVLDGLKAGEKVMVDGFQKLPRGKPGDPIVVQPVPW
QPAGAAPAGGASAPAAGASAAQAPASSASAPAKQ

Specific function: Cell membrane lipoprotein, involved in cell membrane permeability to hydrophobic compounds such as antibiotics, dyes and detergents [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786668, Length=376, Percent_Identity=47.6063829787234, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1789665, Length=381, Percent_Identity=43.5695538057743, Blast_Score=304, Evalue=8e-84,
Organism=Escherichia coli, GI1789929, Length=372, Percent_Identity=41.9354838709677, Blast_Score=279, Evalue=3e-76,
Organism=Escherichia coli, GI87082036, Length=313, Percent_Identity=31.3099041533546, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI87081796, Length=353, Percent_Identity=25.2124645892351, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44423; Mature: 44423

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRLSVETAVSAAPLRRTARSGLFCLALLAAATLAACGKSGGSDQQGQGGTPPPPQVGVV
CEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
TVSPGDVGLVTELPGRLEASRVAQVRARAAGILQKRLFTEGSDVKAGQRLFAIDDAPYRA
EECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHH
SLESAQASVAQAEANVAQARALAERYKPLVAVNAVSRQEYDNAVASQKTAEANLAAARAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHE
VTTARINLGYAAVTAPISGRIGRALVTEGALVGQGEATQLAVIQQIDPLYVNFTQSASDA
EEEEEEECCEEEEECCCCCCCCHHHHHCCCEECCCCCCEEHEEHHCCCEEEEECCCCCHH
LKLKAGLASGKYKQAAKGAASVSVVMEDGSVHPQTGKLLFTDLSVDPTSGQVTLRAEVPN
HHHHHCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEEECCC
PERQLLPGLYVRVRLEQAQVDNGVLLPQQAVTRSARGDTVMVVGPDNHLAPRPVKLGPAQ
CHHHHCCCEEEEEEEEHHCCCCCEECCHHHHHHCCCCCEEEEECCCCCCCCCCEEECCCC
GTNWVVLDGLKAGEKVMVDGFQKLPRGKPGDPIVVQPVPWQPAGAAPAGGASAPAAGASA
CCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCH
AQAPASSASAPAKQ
HCCCCCCCCCCCCC
>Mature Secondary Structure
MYRLSVETAVSAAPLRRTARSGLFCLALLAAATLAACGKSGGSDQQGQGGTPPPPQVGVV
CEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
TVSPGDVGLVTELPGRLEASRVAQVRARAAGILQKRLFTEGSDVKAGQRLFAIDDAPYRA
EECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHH
SLESAQASVAQAEANVAQARALAERYKPLVAVNAVSRQEYDNAVASQKTAEANLAAARAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHE
VTTARINLGYAAVTAPISGRIGRALVTEGALVGQGEATQLAVIQQIDPLYVNFTQSASDA
EEEEEEECCEEEEECCCCCCCCHHHHHCCCEECCCCCCEEHEEHHCCCEEEEECCCCCHH
LKLKAGLASGKYKQAAKGAASVSVVMEDGSVHPQTGKLLFTDLSVDPTSGQVTLRAEVPN
HHHHHCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEEECCC
PERQLLPGLYVRVRLEQAQVDNGVLLPQQAVTRSARGDTVMVVGPDNHLAPRPVKLGPAQ
CHHHHCCCEEEEEEEEHHCCCCCEECCHHHHHHCCCCCEEEEECCCCCCCCCCEEECCCC
GTNWVVLDGLKAGEKVMVDGFQKLPRGKPGDPIVVQPVPWQPAGAAPAGGASAPAAGASA
CCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCH
AQAPASSASAPAKQ
HCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8196548 [H]