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The map label for this gene is slyA [H]

Identifier: 120609027

GI number: 120609027

Start: 357400

End: 357894

Strand: Reverse

Name: slyA [H]

Synonym: Aave_0324

Alternate gene names: 120609027

Gene position: 357894-357400 (Counterclockwise)

Preceding gene: 120609028

Following gene: 120609026

Centisome position: 6.69

GC content: 70.71

Gene sequence:

>495_bases
ATGCACTCACCCCACGACGCCACGCCCTCCGTCCATCCAGAGCTGATCGAGCAGAGCATCGGCTACCAGATGCGCCGCAT
CGTCAGCCTGATGGGCAACGAGGTGGACCGCCGGGTGGAACCCCTGGGGCTGACCGATGCGCAATGGCGGCCCCTGCTGC
GCATCTTCCTGGCTTCGGGCCAGGAAAGCACGGTCGCGGCCCTGGCACGCGTCTGCCAGCTGGACGCAGGCGGCATGACG
CGGCTGCTGGACCGGCTGGAGGCCAAGGGCCTGTGCCGCCGCGAGCGCTCGCAGGAGGACCGCCGGGTGGTCAACCTCGC
CCTGACCGAAGAAGGCCAGGCCGCCGCGGCCCAGTTGCCGGAATTGCTGCAGGACCTGCAGCGCACCGCCCTGCACGGGT
TCAGCGATGCGGAAGCCGCCGCGCTGCGCCGCTACCTGGCCCGCATCTACGACAACCTGACCACGCGGCTCACGCCGCCG
CCGGACGCCCAGTAA

Upstream 100 bases:

>100_bases
TGCCGGAGGACACGCCTCCCACCGCTATGCCAACGGGCCGACCGGGGTGCCCTGTAATCAAAGACTTGACATTATTTGAT
TAGTCAATTAATGTCACGGC

Downstream 100 bases:

>100_bases
GACCCCCCGGCCCCTCTTTCCGAGAGCACGACACAACATGAAAAACCTTCTGGCTCCTTCCTCCTCCGTTGCGGCGGTGC
CGCATGCGCAGCCGGCTGGC

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MHSPHDATPSVHPELIEQSIGYQMRRIVSLMGNEVDRRVEPLGLTDAQWRPLLRIFLASGQESTVAALARVCQLDAGGMT
RLLDRLEAKGLCRRERSQEDRRVVNLALTEEGQAAAAQLPELLQDLQRTALHGFSDAEAAALRRYLARIYDNLTTRLTPP
PDAQ

Sequences:

>Translated_164_residues
MHSPHDATPSVHPELIEQSIGYQMRRIVSLMGNEVDRRVEPLGLTDAQWRPLLRIFLASGQESTVAALARVCQLDAGGMT
RLLDRLEAKGLCRRERSQEDRRVVNLALTEEGQAAAAQLPELLQDLQRTALHGFSDAEAAALRRYLARIYDNLTTRLTPP
PDAQ
>Mature_164_residues
MHSPHDATPSVHPELIEQSIGYQMRRIVSLMGNEVDRRVEPLGLTDAQWRPLLRIFLASGQESTVAALARVCQLDAGGMT
RLLDRLEAKGLCRRERSQEDRRVVNLALTEEGQAAAAQLPELLQDLQRTALHGFSDAEAAALRRYLARIYDNLTTRLTPP
PDAQ

Specific function: Transcription regulator that either activates or represses expression of target genes. Required to activate expression of virulent genes [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081950, Length=138, Percent_Identity=28.2608695652174, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023071
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 18306; Mature: 18306

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSPHDATPSVHPELIEQSIGYQMRRIVSLMGNEVDRRVEPLGLTDAQWRPLLRIFLASG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
QESTVAALARVCQLDAGGMTRLLDRLEAKGLCRRERSQEDRRVVNLALTEEGQAAAAQLP
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ELLQDLQRTALHGFSDAEAAALRRYLARIYDNLTTRLTPPPDAQ
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MHSPHDATPSVHPELIEQSIGYQMRRIVSLMGNEVDRRVEPLGLTDAQWRPLLRIFLASG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
QESTVAALARVCQLDAGGMTRLLDRLEAKGLCRRERSQEDRRVVNLALTEEGQAAAAQLP
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ELLQDLQRTALHGFSDAEAAALRRYLARIYDNLTTRLTPPPDAQ
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10385201; 11939575 [H]