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The map label for this gene is dprE1 [H]

Identifier: 120608774

GI number: 120608774

Start: 68878

End: 70185

Strand: Reverse

Name: dprE1 [H]

Synonym: Aave_0063

Alternate gene names: 120608774

Gene position: 70185-68878 (Counterclockwise)

Preceding gene: 120608775

Following gene: 120608773

Centisome position: 1.31

GC content: 71.56

Gene sequence:

>1308_bases
GTGGTAGCAGTGCACTCCTGGGGCCGGCTGCGGGCGGCCGAGCATGCGCTGCGCGCGCTGTCGGAGCATCCACCCGCGCG
GCTGCCGCTGCCGGCCGGCCAGCACGGCCTGGCCTACGGCATGGGCCGCAGCTATGGCGACGTCTGCCTGAACCCTGGCG
GCACACTCTGGGCCACGCGCGGGCAGGACCGCTTCATCGCCTGGGACGAGGCCACGGGCGAACTCACCTGCGAAGCCGGC
GTGCTGCTGCGCGACATCCAGCGCACCTTCATCCCGCGCGGCTGGATGCTGCCCGTCACGCCCGGCACGCAGTTCGCCAC
CGTGGGCGGCGCCATCGCCAACGATGTCCATGGCAAGAACCACCACGTCCACGGCAGCTTCGGCGACCACGTGCTGGCGC
TGCACCTGCTGCGCACCGACGGCCTGCTGGTGCGCTGCGGGCCCGACCTGCGGCCCGACTGGTTCTGCGCCACGGTCGGC
GGGCTGGGCCTGACGGGCGTGGTCACGCAGGCCACGCTGCGGCTGCGCAGGGTGGCCGGCCCGTGGCTCGATACCGAAAC
GCTGCCCTACGGCAGCCTGCGGGAGTTCTTCACCCTCGCGGACGCCTCGGAAGCCGGATGGGAATACACGGTTTCGTGGA
TCGACTGCCTCGCCGGTGCCGATGCGCGCGGCATCTTCATGCGCGGCAACCACGTGCCCGGCCCGGTGGCGAAGCCGCCT
CCCGAGCCCCGGGGCGGCAAGCGCACCGTGCAGTTCGTTCCTCCCGTCTCGCTGGTGAACCGCTGGAGCCTGCGGCCCTT
CAACACCGCCTATTACCACCTGCACAAGCGGCGGGCGGGCCGGGCGCTGCAGCACTACGAACCCTTTTTCTACCCGCTGG
ACAACCTCCTGGAATGGAACCGCATCTACGGCCGCCGGGGCTTCTACCAGTACCAGTGCGTCGTCCCCCGCGAAGGCGGC
GAGGACGCCGTGGCCGCGCTGCTGCGCGAGATCGCGGCATCGGGGCAGGGCTCGTTCCTGGGGGTGCTCAAGACCTTCGG
GCAGCGCCGGCCCCTGGGCATGCTGAGCTTTCCCATGCCCGGCGTCACCCTCGCCCTGGACTTCCCCAACCTGGGCGAGC
CGACGCTGCGGCTCTTCGAACGCCTCGATGCCGTGGTGGCTTCGGCGGGCGGCCGGCTCTATGCGGCCAAGGACGCGCGC
ATGCCGCGCACACTGTTCGAGGCCGGCTATCCCCGGCTGCCTGAATTCCTGCCCTACCGCGACCCCCGCATCCGCTCCGC
CATGTCGCTGCGGCTGCTCGGCGACTGA

Upstream 100 bases:

>100_bases
ACGATCCGCTCGTCTTCGCGTTCAAGGATCGCGCCAGCCTGGTGGCCGGCGCGGTGTTCGTGGCGGCGCTCGCGGCCGCC
GCCACGGGACCGGGGTGGCC

Downstream 100 bases:

>100_bases
CCGCCGGGGGCATTCCGCGCCCTCCCCTCTTTTTCCGCCCGCTCCGCCAACGGCACCAACCCATCGCCCGCCATGCCCGA
TACCTCTTCCCCCCGCACCA

Product: FAD linked oxidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MVAVHSWGRLRAAEHALRALSEHPPARLPLPAGQHGLAYGMGRSYGDVCLNPGGTLWATRGQDRFIAWDEATGELTCEAG
VLLRDIQRTFIPRGWMLPVTPGTQFATVGGAIANDVHGKNHHVHGSFGDHVLALHLLRTDGLLVRCGPDLRPDWFCATVG
GLGLTGVVTQATLRLRRVAGPWLDTETLPYGSLREFFTLADASEAGWEYTVSWIDCLAGADARGIFMRGNHVPGPVAKPP
PEPRGGKRTVQFVPPVSLVNRWSLRPFNTAYYHLHKRRAGRALQHYEPFFYPLDNLLEWNRIYGRRGFYQYQCVVPREGG
EDAVAALLREIAASGQGSFLGVLKTFGQRRPLGMLSFPMPGVTLALDFPNLGEPTLRLFERLDAVVASAGGRLYAAKDAR
MPRTLFEAGYPRLPEFLPYRDPRIRSAMSLRLLGD

Sequences:

>Translated_435_residues
MVAVHSWGRLRAAEHALRALSEHPPARLPLPAGQHGLAYGMGRSYGDVCLNPGGTLWATRGQDRFIAWDEATGELTCEAG
VLLRDIQRTFIPRGWMLPVTPGTQFATVGGAIANDVHGKNHHVHGSFGDHVLALHLLRTDGLLVRCGPDLRPDWFCATVG
GLGLTGVVTQATLRLRRVAGPWLDTETLPYGSLREFFTLADASEAGWEYTVSWIDCLAGADARGIFMRGNHVPGPVAKPP
PEPRGGKRTVQFVPPVSLVNRWSLRPFNTAYYHLHKRRAGRALQHYEPFFYPLDNLLEWNRIYGRRGFYQYQCVVPREGG
EDAVAALLREIAASGQGSFLGVLKTFGQRRPLGMLSFPMPGVTLALDFPNLGEPTLRLFERLDAVVASAGGRLYAAKDAR
MPRTLFEAGYPRLPEFLPYRDPRIRSAMSLRLLGD
>Mature_435_residues
MVAVHSWGRLRAAEHALRALSEHPPARLPLPAGQHGLAYGMGRSYGDVCLNPGGTLWATRGQDRFIAWDEATGELTCEAG
VLLRDIQRTFIPRGWMLPVTPGTQFATVGGAIANDVHGKNHHVHGSFGDHVLALHLLRTDGLLVRCGPDLRPDWFCATVG
GLGLTGVVTQATLRLRRVAGPWLDTETLPYGSLREFFTLADASEAGWEYTVSWIDCLAGADARGIFMRGNHVPGPVAKPP
PEPRGGKRTVQFVPPVSLVNRWSLRPFNTAYYHLHKRRAGRALQHYEPFFYPLDNLLEWNRIYGRRGFYQYQCVVPREGG
EDAVAALLREIAASGQGSFLGVLKTFGQRRPLGMLSFPMPGVTLALDFPNLGEPTLRLFERLDAVVASAGGRLYAAKDAR
MPRTLFEAGYPRLPEFLPYRDPRIRSAMSLRLLGD

Specific function: Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007173
- InterPro:   IPR016166
- InterPro:   IPR016168
- InterPro:   IPR006094 [H]

Pfam domain/function: PF04030 ALO; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 48064; Mature: 48064

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAVHSWGRLRAAEHALRALSEHPPARLPLPAGQHGLAYGMGRSYGDVCLNPGGTLWATR
CEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCEEECCCCCEEEEC
GQDRFIAWDEATGELTCEAGVLLRDIQRTFIPRGWMLPVTPGTQFATVGGAIANDVHGKN
CCCCEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCEEECCCCCCEEHHCCHHHHCCCCCC
HHVHGSFGDHVLALHLLRTDGLLVRCGPDLRPDWFCATVGGLGLTGVVTQATLRLRRVAG
CEECCCCCCCEEEEEEECCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
PWLDTETLPYGSLREFFTLADASEAGWEYTVSWIDCLAGADARGIFMRGNHVPGPVAKPP
CCCCCCCCCCCHHHHHHHHCCCCCCCCEEEHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
PEPRGGKRTVQFVPPVSLVNRWSLRPFNTAYYHLHKRRAGRALQHYEPFFYPLDNLLEWN
CCCCCCCEEEEEECCHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHCCCCHHCHHHHHHHH
RIYGRRGFYQYQCVVPREGGEDAVAALLREIAASGQGSFLGVLKTFGQRRPLGMLSFPMP
HHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEECCCC
GVTLALDFPNLGEPTLRLFERLDAVVASAGGRLYAAKDARMPRTLFEAGYPRLPEFLPYR
CEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCC
DPRIRSAMSLRLLGD
CCHHHHHEEEEEECC
>Mature Secondary Structure
MVAVHSWGRLRAAEHALRALSEHPPARLPLPAGQHGLAYGMGRSYGDVCLNPGGTLWATR
CEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCEEECCCCCEEEEC
GQDRFIAWDEATGELTCEAGVLLRDIQRTFIPRGWMLPVTPGTQFATVGGAIANDVHGKN
CCCCEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCEEECCCCCCEEHHCCHHHHCCCCCC
HHVHGSFGDHVLALHLLRTDGLLVRCGPDLRPDWFCATVGGLGLTGVVTQATLRLRRVAG
CEECCCCCCCEEEEEEECCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
PWLDTETLPYGSLREFFTLADASEAGWEYTVSWIDCLAGADARGIFMRGNHVPGPVAKPP
CCCCCCCCCCCHHHHHHHHCCCCCCCCEEEHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
PEPRGGKRTVQFVPPVSLVNRWSLRPFNTAYYHLHKRRAGRALQHYEPFFYPLDNLLEWN
CCCCCCCEEEEEECCHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHCCCCHHCHHHHHHHH
RIYGRRGFYQYQCVVPREGGEDAVAALLREIAASGQGSFLGVLKTFGQRRPLGMLSFPMP
HHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEECCCC
GVTLALDFPNLGEPTLRLFERLDAVVASAGGRLYAAKDARMPRTLFEAGYPRLPEFLPYR
CEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCC
DPRIRSAMSLRLLGD
CCHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]