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The map label for this gene is hsdR [H]

Identifier: 120608719

GI number: 120608719

Start: 7309

End: 7668

Strand: Reverse

Name: hsdR [H]

Synonym: Aave_0005

Alternate gene names: 120608719

Gene position: 7668-7309 (Counterclockwise)

Preceding gene: 120608720

Following gene: 120608718

Centisome position: 0.14

GC content: 62.78

Gene sequence:

>360_bases
ATGGACAAGAAAAACTGGAGCGAAACCGACGTTTGCGAGAAGCGCATCAGTCCGGCCATTGCCTGCGCTGGCTGGGATCT
GATCACCCAGGTGCTGCGCGAGTACACGTTGCGTGCAGGACGGGTGGTGGTGCGTGGAAATACTGCATTTCGCGACAAGA
ACAGTATCTTGCGTGCGGACTACGTCCTGTTCCACAAGCCCAAGGTTCCGCTGGCAGTGGTCGGCATCGTCACCCGCGTC
ACCGCCCTGCGCCGCCTGTGCGCCGACCTGCGCCAGCGCCTGGCCAAACGCCAGTCCGTGCAGGCCCGTCTGGCCGAGGC
GCTGGTGGAGACCGCTAGCTTTTCTTCGGAGCCTTGCTGA

Upstream 100 bases:

>100_bases
GCGGTGCGGGGGTAGGTGCCTGCATGCGGATTCCTCTCGGATAATGATCCTTCCTGCCGTGGATAGGTGAGGCCAGGGCT
GGAAGAACGGGCGAGGAGCC

Downstream 100 bases:

>100_bases
TGAATCCCACCGCCCTGCGAGCCATGTTGGAGTCCTTGCGGAGTCTGCCGCGTGAGCAGGCGGTGGTGGAGTTCAAGTCG
AATTTGGCCGATCCCGAGAA

Product: putative type I restriction enzyme, R subunit

Products: NA

Alternate protein names: R.EcoEI [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MDKKNWSETDVCEKRISPAIACAGWDLITQVLREYTLRAGRVVVRGNTAFRDKNSILRADYVLFHKPKVPLAVVGIVTRV
TALRRLCADLRQRLAKRQSVQARLAEALVETASFSSEPC

Sequences:

>Translated_119_residues
MDKKNWSETDVCEKRISPAIACAGWDLITQVLREYTLRAGRVVVRGNTAFRDKNSILRADYVLFHKPKVPLAVVGIVTRV
TALRRLCADLRQRLAKRQSVQARLAEALVETASFSSEPC
>Mature_119_residues
MDKKNWSETDVCEKRISPAIACAGWDLITQVLREYTLRAGRVVVRGNTAFRDKNSILRADYVLFHKPKVPLAVVGIVTRV
TALRRLCADLRQRLAKRQSVQARLAEALVETASFSSEPC

Specific function: The EcoEI enzyme recognizes 5'-GAGN(7)ATGC-3'. Subunit R is required for both nuclease and ATPase activities, but not for modification [H]

COG id: COG4096

COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR013670
- InterPro:   IPR007409 [H]

Pfam domain/function: PF08463 EcoEI_R_C; PF04313 HSDR_N; PF04851 ResIII [H]

EC number: =3.1.21.3 [H]

Molecular weight: Translated: 13385; Mature: 13385

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKNWSETDVCEKRISPAIACAGWDLITQVLREYTLRAGRVVVRGNTAFRDKNSILRAD
CCCCCCCHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHH
YVLFHKPKVPLAVVGIVTRVTALRRLCADLRQRLAKRQSVQARLAEALVETASFSSEPC
HHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDKKNWSETDVCEKRISPAIACAGWDLITQVLREYTLRAGRVVVRGNTAFRDKNSILRAD
CCCCCCCHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHH
YVLFHKPKVPLAVVGIVTRVTALRRLCADLRQRLAKRQSVQARLAEALVETASFSSEPC
HHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8412658 [H]