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The map label for this gene is scoA [H]

Identifier: 120599115

GI number: 120599115

Start: 2665661

End: 2666365

Strand: Direct

Name: scoA [H]

Synonym: Sputw3181_2311

Alternate gene names: 120599115

Gene position: 2665661-2666365 (Clockwise)

Preceding gene: 120599114

Following gene: 120599116

Centisome position: 56.62

GC content: 50.92

Gene sequence:

>705_bases
ATGGCAGGACTCAATAAAGTCGTCAGCAGCTATGAAGAAGCGTTAACAGGTTTATCCGATGATATGACCATTATGGTTGG
CGGTTTTGGCCTGTGCGGTATTCCTGAAGGCTTAATCAATCAAATGGTGAAGATGGGCGTTAAGGGCTTAACCGCCATTT
CGAACAATGCCGGCGTCGACGATTTCGGCTTGGGCTTATTGTTAAAACATCGCCAGATTTCAACCATGATCGCCTCTTAC
GTGGGTGAGAACGCCACCTTCGAGCAGCAAATGCTCTCGGGTGAATTGAATGTGATTTTAACGCCCCAAGGCACGCTGGC
GGAAAAAATCCGCGCGGGCGGCGCAGGCATTCCGGCGTTTTTCACCGCCACAGGCTACGGCACCCCCGTGGCTGAAGGCA
AAGAAACCCGCGAAATTAAAGGCCGTCACTATGTGTTAGAAGAATCACTGACCGCCAATTTTGCCTTAGTGCGCGCATGG
AAGGCCGATACTATGGGTAACTTAGTGTTCCGCAAAACCGCAGCTAACTTTAACCCTATGATGGCGACTGCGGGCAAAAT
CACTGTGGTGGAAGCCGAGTTTATTGTAGAGCCAGGCGAGCTAGACCCTGATCATATCCACACGCCGGGCATCTATGTTG
ACCGCGTTATTCAAGGCAAGTTCGAGAAACGTATCGAGCAGCGCACGGTAAAAGCCGCGAAATAA

Upstream 100 bases:

>100_bases
ATGGCTCTAAAGTCGCCAATGCAATCTTACAGGGCGCCAAAGCCTAGGTTCTAGGTTCTAGAAATGATTGGACACGAATA
ACAATTTAAAGGACATCAAA

Downstream 100 bases:

>100_bases
AAGGCGCTAGCAAAACCTTGAAACACAGTTAACGCAATTGGCACTTAGATCTCTAGAGTAAAAACTAAGGGTAAAAACCT
AAGAGTAAAGACCAAAGCGT

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MAGLNKVVSSYEEALTGLSDDMTIMVGGFGLCGIPEGLINQMVKMGVKGLTAISNNAGVDDFGLGLLLKHRQISTMIASY
VGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVAEGKETREIKGRHYVLEESLTANFALVRAW
KADTMGNLVFRKTAANFNPMMATAGKITVVEAEFIVEPGELDPDHIHTPGIYVDRVIQGKFEKRIEQRTVKAAK

Sequences:

>Translated_234_residues
MAGLNKVVSSYEEALTGLSDDMTIMVGGFGLCGIPEGLINQMVKMGVKGLTAISNNAGVDDFGLGLLLKHRQISTMIASY
VGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVAEGKETREIKGRHYVLEESLTANFALVRAW
KADTMGNLVFRKTAANFNPMMATAGKITVVEAEFIVEPGELDPDHIHTPGIYVDRVIQGKFEKRIEQRTVKAAK
>Mature_233_residues
AGLNKVVSSYEEALTGLSDDMTIMVGGFGLCGIPEGLINQMVKMGVKGLTAISNNAGVDDFGLGLLLKHRQISTMIASYV
GENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVAEGKETREIKGRHYVLEESLTANFALVRAWK
ADTMGNLVFRKTAANFNPMMATAGKITVVEAEFIVEPGELDPDHIHTPGIYVDRVIQGKFEKRIEQRTVKAAK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=238, Percent_Identity=58.4033613445378, Blast_Score=283, Evalue=1e-76,
Organism=Homo sapiens, GI11545841, Length=237, Percent_Identity=54.0084388185654, Blast_Score=245, Evalue=3e-65,
Organism=Escherichia coli, GI1788551, Length=214, Percent_Identity=45.3271028037383, Blast_Score=195, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17531517, Length=243, Percent_Identity=53.4979423868313, Blast_Score=263, Evalue=4e-71,
Organism=Drosophila melanogaster, GI21358325, Length=248, Percent_Identity=51.6129032258064, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24655794, Length=248, Percent_Identity=51.6129032258064, Blast_Score=248, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25152; Mature: 25021

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLNKVVSSYEEALTGLSDDMTIMVGGFGLCGIPEGLINQMVKMGVKGLTAISNNAGVD
CCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCHHHHEEECCCCCCC
DFGLGLLLKHRQISTMIASYVGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAF
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCCE
FTATGYGTPVAEGKETREIKGRHYVLEESLTANFALVRAWKADTMGNLVFRKTAANFNPM
EEECCCCCCCCCCCCHHHHCCCEEEEECCCCCCEEEEEEECCCCCCCEEEEECCCCCCCC
MATAGKITVVEAEFIVEPGELDPDHIHTPGIYVDRVIQGKFEKRIEQRTVKAAK
EECCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGLNKVVSSYEEALTGLSDDMTIMVGGFGLCGIPEGLINQMVKMGVKGLTAISNNAGVD
CCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCHHHHEEECCCCCCC
DFGLGLLLKHRQISTMIASYVGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAF
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCCE
FTATGYGTPVAEGKETREIKGRHYVLEESLTANFALVRAWKADTMGNLVFRKTAANFNPM
EEECCCCCCCCCCCCHHHHCCCEEEEECCCCCCEEEEEEECCCCCCCEEEEECCCCCCCC
MATAGKITVVEAEFIVEPGELDPDHIHTPGIYVDRVIQGKFEKRIEQRTVKAAK
EECCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]